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https://www.readbyqxmd.com/read/29777643/infertility-psychological-distress-and-coping-strategies-among-women-in-mali-west-africa-a-mixed-methods-study
#1
Rosanna F Hess, Ratchneewan Ross, John L GilillandJr
Relatively little is known about infertility and its consequences in Mali, West Africa where the context and culture are different from those of previously studied settings. This study therefore aimed to specifically examine infertility induced psychological distress and coping strategies among women in Mali. A convergent mixed-methods design-correlational cross-sectional and qualitative descriptive-guided the study. Fifty-eight infertile Malian women participated: 52 completed the Psychological Evaluation Test specific for infertility and a question on general health status, and 26 were interviewed in-depth...
March 2018: African Journal of Reproductive Health
https://www.readbyqxmd.com/read/29773386/electroconductive-3d-polymeric-network-production-by-using-polyaniline-chitosan-based-hydrogel
#2
Celil Ulutürk, Neslihan Alemdar
Herein, polyaniline/chitosan(PANI/CTS)-based electroconductive hydrogel was produced by photocrosslinked network in which CTS was used as a main component. Firstly, glycidyl methacrylate (GMA) was grafted on the CTS backbone to form CTS-g-GMA. Then, a three-dimensional polymeric network consisting of CTS-g-GMA and poly(ethylene glycol)diacrylate (PEGDA) was obtained by using photocrosslinking technique. At last, aniline monomer solution prepared by utilizing three different aniline concentrations (0.08, 0.16 and 0,32 M) was absorbed into (CTS-g-GMA)-PEGDA crosslinked structure to form [(CTS-g-GMA)-PEGDA]-PANI electroconductive semi interpenetrating network...
August 1, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29773361/degradation-properties-of-chitosan-microspheres-poly-l-lactic-acid-composite-in-vitro-and-in-vivo
#3
Zhenzhao Guo, Dongying Bo, Yuan He, Xueshi Luo, Hong Li
Poly(L-lactic acid) (PLLA) is a popular biodegradable polymer, but the accumulated acid production by degradation is a bottleneck for its extended utilization. In this study, chitosan microspheres (CSMs) were introduced into PLLA porous matrices to manipulate the acid microclimate from PLLA degradation. In vitro and in vivo degradation were, respectively, performed in PBS and implanted into rat's subcutaneous. The results indicated that pH of CSMs/PLLA composites remained stable of around 7.50 in vitro until six weeks...
August 1, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29772346/tackling-bioactive-glass-excessive-in-vitro-bioreactivity-preconditioning-approaches-for-cell-culture-tests
#4
REVIEW
Francesca E Ciraldo, Elena Boccardi, Virginia Melli, Fabian Westhauser, Aldo R Boccaccini
Bioactive glasses (BGs) are being increasingly considered for biomedical applications in bone and soft tissue replacement approaches thanks to their ability to form strong bonding with tissues. However, due to their high reactivity once in contact with water-based solutions BGs rapidly exchange ions with the surrounding environment leading in most cases to an undesired increase of the pH under static in vitro conditions (due to alkaline ion "burst release"), making difficult or even impossible to perform cell culture studies...
May 14, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29771925/in-vitro-and-in-vivo-biological-performance-of-porous-ti-alloys-prepared-by-powder-metallurgy
#5
Renata Falchete do Prado, Gabriela Campos Esteves, Evelyn Luzia De Souza Santos, Daiane Acácia Griti Bueno, Carlos Alberto Alves Cairo, Luis Gustavo Oliveira De Vasconcellos, Renata Silveira Sagnori, Fernanda Bastos Pereira Tessarin, Felipe Eduardo Oliveira, Luciane Dias De Oliveira, Maria Fernanda Lima Villaça-Carvalho, Vinicius André Rodrigues Henriques, Yasmin Rodarte Carvalho, Luana Marotta Reis De Vasconcellos
Titanium (Ti) and Ti-6 Aluminium-4 Vanadium alloys are the most common materials in implants composition but β type alloys are promising biomaterials because they present better mechanical properties. Besides the composition of biomaterial, many factors influence the performance of the biomaterial. For example, porous surface may modify the functional cellular response and accelerate osseointegration. This paper presents in vitro and in vivo evaluations of powder metallurgy-processed porous samples composed by different titanium alloys and pure Ti, aiming to show their potential for biomedical applications...
2018: PloS One
https://www.readbyqxmd.com/read/29770191/electrolytically-generated-hydrogen-warm-water-cleanses-the-keratin-plug-clogged-hair-pores-and-promotes-the-capillary-blood-streams-more-markedly-than-normal-warm-water-does
#6
Yoshiharu Tanaka, Yasukazu Saitoh, Nobuhiko Miwa
Biomedical properties of hydrogen water have been extensively investigated, but the effect of hydrogen on good healthy subjects remains unclear. This study was designed to explore the hygiene improvement by electrolytically generated hydrogen warm water (40°C) on capillary blood streams, skin moisture, and keratin plugs in skin pores in normal good healthy subjects with their informed consents. Fingertip-capillary blood stream was estimated after hand-immersing in hydrogen warm water by videography using a CCD-based microscope, and the blood flow levels increased to about 120% versus normal warm water, after 60 minutes of the hand-immersing termination...
January 2018: Medical Gas Research
https://www.readbyqxmd.com/read/29767347/enhanced-plasmonic-biosensors-of-hybrid-gold-nanoparticle-graphene-oxide-based-label-free-immunoassay
#7
Nan-Fu Chiu, Chi-Chu Chen, Cheng-Du Yang, Yu-Sheng Kao, Wei-Ren Wu
In this study, we propose a modified gold nanoparticle-graphene oxide sheet (AuNP-GO) nanocomposite to detect two different interactions between proteins and hybrid nanocomposites for use in biomedical applications. GO sheets have high bioaffinity, which facilitates the attachment of biomolecules to carboxyl groups and has led to its use in the development of sensing mechanisms. When GO sheets are decorated with AuNPs, they introduce localized surface plasmon resonance (LSPR) in the resonance energy transfer of spectral changes...
May 16, 2018: Nanoscale Research Letters
https://www.readbyqxmd.com/read/29766712/highly-sensitive-membrane-based-pressure-sensors-meps-for-real-time-monitoring-of-catalytic-reactions
#8
Alessandra Zizzari, Monica Bianco, Loretta L Del Mercato, Antonio Sorarù, Mauro Carraro, Paolo Pellegrino, Elisabetta Perrone, Anna Grazia Monteduro, Marcella Bonchio, Rosaria Rinaldi, Ilenia Viola, Valentina Arima
Functional, flexible and integrated lab-on-chips, based on elastic membranes, are capable of fine response to external stimuli, so to pave the way for many applications as multiplexed sensors for a wide range of chemical, physical and biomedical processes. Here, we report on the use of elastic thin membranes (TMs), integrated with a reaction chamber, to fabricate a Membrane-based Pressure Sensor (MePS) for reaction monitoring. In particular, the TM becomes the key-element in the design of a highly sensitive MePS capable to monitor gaseous species production in dynamic and temporally fast processes with high resolution and reproducibility...
May 16, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29765680/the-relationship-between-substrate-morphology-and-biological-performances-of-nano-silver-loaded-dopamine-coatings-on-titanium-surfaces
#9
Weibo Zhang, Shuang Wang, Shaohua Ge, Jialong Chen, Ping Ji
Biomedical device-associated infection (BAI) and lack of osseointegration are the main causes of implant failure. Therefore, it is imperative for implants not only to depress microbial activity and biofilm colonization but also to prompt osteoblast functions and osseointegration. As part of the coating development for implants, the interest of in vitro studies on the interaction between implant substrate morphology and the coating's biological performances is growing. In this study, by harnessing the adhesion and reactivity of bioinspired polydopamine, nano-silver was successfully anchored onto micro/nanoporous as well as smooth titanium surfaces to analyse the effect of substrate morphology on biological performances of the coatings...
April 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29763706/exploiting-semantic-patterns-over-biomedical-knowledge-graphs-for-predicting-treatment-and-causative-relations
#10
Gokhan Bakal, Preetham Talari, Elijah V Kakani, Ramakanth Kavuluru
BACKGROUND: Identifying new potential treatment options for medical conditions that cause human disease burden is a central task of biomedical research. Since all candidate drugs cannot be tested with animal and clinical trials, in vitro approaches are first attempted to identify promising candidates. Likewise, identifying different causal relations between biomedical entities is also critical to understand biomedical processes. Generally, natural language processing (NLP) and machine learning are used to predict specific relations between any given pair of entities using the distant supervision approach...
May 12, 2018: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29763548/zein-increases-the-cytoaffinity-and-biodegradability-of-scaffolds-3d-printed-with-zein-and-poly-%C3%AE%C2%B5-caprolactone-composite-ink
#11
Linzhi Jing, Xiang Wang, Hang Liu, Yuyun Lu, Jinsong Bian, Jie Sun, Dejian Huang
Electrohydrodynamic printing (EHDP) has attracted extensive interests as a powerful technology to fabricate micro to nanoscale fibrous scaffolds in a custom-tailored manner for biomedical applications. A few synthetic biopolymer inks are applicable to this EHDP technology, but the fabricated scaffolds suffered from low mechanical strength, biocompatibility and biodegradability. In this study, a series of poly(ε-caprolactone)(PCL)/zein composite inks were developed and their printability was examined on a solution-based EHDP system for scaffold fabrication...
May 15, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29760988/intra-class-variability-in-diffuse-reflectance-spectroscopy-application-to-porcine-adipose-tissue
#12
Félix Fanjul-Vélez, Laura Arévalo-Díaz, José L Arce-Diego
Optical diffuse reflectance spectroscopy (DRS) has great potential in the study, diagnosis, and discrimination of biological tissues. Discrimination is based on massive measurements that conform training sets. These sets are then used to classify tissues according to the biomedical application. Classification accuracy depends strongly on the training dataset, which typically comes from different samples of the same class, and from different points of the same sample. The variability of these measurements is not usually considered and is assumed to be purely random, although it could greatly influence the results...
May 1, 2018: Biomedical Optics Express
https://www.readbyqxmd.com/read/29760549/nanostructured-ag-substituted-fluorhydroxyapatite-tio-2-coatings-for-enhanced-bactericidal-effects-and-osteoinductivity-of-ti-for-biomedical-applications
#13
Yong Huang, Guiqin Song, Xiaotong Chang, Zhenhui Wang, Xuejiao Zhang, Shuguang Han, Zhuobin Su, Hejie Yang, Dongdong Yang, Xiaojun Zhang
Background: Poor mechanical properties, undesirable fast dissolution rate, and lack of antibacterial activity limit the application of hydroxyapatite (HA) as an implant coating material. To overcome these limitations, a hybrid coating of Ag+ -substituted fluorhydroxyapatite and titania nanotube (TNT) was prepared. Methods: The incorporation of silver into the HA-TiO2 hybrid coating improves its antimicrobial properties. The addition of F as a second binary element increases the structural stability of the coating...
2018: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29757744/-block-chain-reaction-a-blockchain-revolution-sweeps-into-health-care-offering-the-possibility-for-a-much-needed-data-solution
#14
Leslie Mertz
Electronic health records may have digitized patient data, but getting that data from one clinician to another remains a huge challenge, especially since patients often have multiple doctors ordering tests, prescribing drugs, and providing treatment. Many experts now believe that blockchain technology might be just the thing to get a patient's pertinent medical information from where it is stored to where it is needed, as well as to allow patients to easily view their own medical histories. In addition, blockchain technology might also be able to help with other aspects of health care, such as improving the insurance claim or other administrative processes within healthcare networks and making health-related population data available to biomedical researchers...
May 2018: IEEE Pulse
https://www.readbyqxmd.com/read/29753964/a-web-based-system-for-neural-network-based-classification-in-temporomandibular-joint-osteoarthritis
#15
Priscille de Dumast, Clément Mirabel, Lucia Cevidanes, Antonio Ruellas, Marilia Yatabe, Marcos Ioshida, Nina Tubau Ribera, Loic Michoud, Liliane Gomes, Chao Huang, Hongtu Zhu, Luciana Muniz, Brandon Shoukri, Beatriz Paniagua, Martin Styner, Steve Pieper, Francois Budin, Jean-Baptiste Vimort, Laura Pascal, Juan Carlos Prieto
OBJECTIVE: The purpose of this study is to describe the methodological innovations of a web-based system for storage, integration and computation of biomedical data, using a training imaging dataset to remotely compute a deep neural network classifier of temporomandibular joint osteoarthritis (TMJOA). METHODS: This study imaging dataset consisted of three-dimensional (3D) surface meshes of mandibular condyles constructed from cone beam computed tomography (CBCT) scans...
May 1, 2018: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/29752159/predictors-of-falls-and-fractures-leading-to-hospitalization-in-people-with-dementia-a-representative-cohort-study
#16
Shalini Sharma, Christoph Mueller, Robert Stewart, Nicola Veronese, Davy Vancampfort, Ai Koyanagi, Sarah E Lamb, Gayan Perera, Brendon Stubbs
OBJECTIVES: Investigate predictors of falls and fractures leading to hospitalization in a large cohort of people with dementia. DESIGN: A retrospective cohort study. SETTING AND PARTICIPANTS: People with diagnosed dementia between January 2007 and March 2013, aged >65 years, were assembled using data from the Maudsley Biomedical Research Centre Case Register, from 4 boroughs in London serving a population of 1.3 million people. MEASURES: Falls and/or fractures leading to hospitalization were ascertained from linked national records...
May 2, 2018: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29752090/one-step-preparation-of-polymeric-maltitol-particles-from-a-sugar-molecule-maltitol-for-biomedical-applications
#17
Nurettin Sahiner
Here, a facile method for the preparation of polymeric particles from a sugar molecule, maltitol (ML) in single step was reported via microemulsion polymerization/crosslinking technique with a high yield, 89 ± 6%. Furthermore, poly(Maltitol) (p(ML)) particles were chemically modified to induce different physicochemical characteristic using different anionic and cationic modifying agents such as taurine (TA) and diethylenetriamine (DETA) to prepare m-p(ML)/TA and m-p(ML)/DETA. The blood compatibility of the p(ML) particles and their modified forms were tested with fresh blood, and found that p(ML) and m-(ML)/DETA particles are blood compatible with about 5% hemolysis, and above 80% blood clotting indices...
August 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29751681/biometric-authentication-using-the-ppg-a-long-term-feasibility-study
#18
Jorge Sancho, Álvaro Alesanco, José García
The photoplethysmogram (PPG) is a biomedical signal that can be used to estimate volumetric blood flow changes in the peripheral circulation. During the past few years, several works have been published in order to assess the potential for PPGs to be used in biometric authentication systems, but results are inconclusive. In this paper we perform an analysis of the feasibility of using the PPG as a realistic biometric alternative in the long term. Several feature extractors (based on the time domain and the Karhunen⁻Loève transform) and matching metrics (Manhattan and Euclidean distances) have been tested using four different PPG databases (PRRB, MIMIC-II, Berry, and Nonin)...
May 11, 2018: Sensors
https://www.readbyqxmd.com/read/29751344/development-of-ph-responsive-biopolymer-silica-composites-loaded-with-larrea-divaricata-cav-extract-with-antioxidant-activity
#19
María Inés Alvarez Echazú, Christian Ezequiel Olivetti, Ignacio Peralta, Maria Rosario Alonso, Claudia Anesini, Claudio Javier Perez, Gisela Solange Alvarez, Martin Federico Desimone
A detailed study of biomaterials is mandatory to comprehend their feasible biomedical applications in terms of drug delivery and tissue regeneration. Particularly, mucoadhesive biopolymers such as chitosan (chi) and carboxymethylcellulose (CMC) have become interesting biomaterials regards to their biocompatibility and non-toxicity for oral mucosal drug delivery. In this work, pH-responsive biopolymer-silica composites (Chi-SiO2 , Chi-CMC-SiO2 ) were developed. These two types of composites presented a different swelling behavior due to the environmental pH...
May 7, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29750034/physiologically-based-pharmacokinetic-modeling-of-nanoceria-systemic-distribution-in-rats-suggests-dose-and-route-dependent-biokinetics
#20
Ulrika Carlander, Tshepo Paulsen Moto, Anteneh Assefa Desalegn, Robert A Yokel, Gunnar Johanson
Background: Cerium dioxide nanoparticles (nanoceria) are increasingly being used in a variety of products as catalysts, coatings, and polishing agents. Furthermore, their antioxidant properties make nanoceria potential candidates for biomedical applications. To predict and avoid toxicity, information about their biokinetics is essential. A useful tool to explore such associations between exposure and internal target dose is physiologically based pharmacokinetic (PBPK) modeling. The aim of this study was to test the appropriateness of our previously published PBPK model developed for intravenous (IV) administration when applied to various sizes of nanoceria and to exposure routes relevant for humans...
2018: International Journal of Nanomedicine
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