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abdominal aortic dissection

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https://www.readbyqxmd.com/read/29036197/morphometric-measurements-of-systemic-atherosclerosis-and-visceral-fat-evidence-from-an-autopsy-study
#1
Aline Nishizawa, Claudia K Suemoto, Daniela S Farias-Itao, Fernanda M Campos, Karen C S Silva, Marcio S Bittencourt, Lea T Grinberg, Renata E P Leite, Renata E L Ferretti-Rebustini, Jose M Farfel, Wilson Jacob-Filho, Carlos A Pasqualucci
BACKGROUND: Morphometric measurements of systemic atherosclerosis and direct quantification of visceral fat are only possible using materials from autopsy studies. However, the few autopsy studies that have investigated the association of visceral fat with atherosclerosis had small sample sizes and focused on coronary arteries of young or middle-aged White subjects. We aimed to investigate the association of pericardial fat (PF) and abdominal visceral fat (AVF) with atherosclerosis in the aorta, coronary, carotid, and cerebral arteries in a large autopsy study...
2017: PloS One
https://www.readbyqxmd.com/read/29034037/characteristics-of-abdominal-aortic-aneurysm-in-japanese-patients-aged-50-years-or-younger
#2
Mitsunori Nakano, Naoyuki Kimura, Harunobu Matsumoto, Tomoyasu Hirano, Koichi Adachi, Koichi Yuri, Atsushi Yamaguchi, Hideo Adachi
Objective: We investigated the characteristics and surgical outcomes of abdominal aortic aneurysm (AAA), which typically occurs in elderly persons, in Japanese patients aged 50 years or younger. Materials and Methods: Clinical records of 999 patients who underwent open or endovascular repair for AAA at our hospital between 2007 and 2015 were reviewed to identify the clinical characteristics and surgical outcomes of young patients with AAA. The cohort included 14 patients aged 50 years or younger (mean, 40.4 years; young group) and 985 patients aged older than 50 years (mean, 72...
June 25, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29030346/diagnostic-accuracy-of-the-aortic-dissection-detection-risk-score-plus-d-dimer-for-acute-aortic-syndromes-the-advised-prospective-multicenter-study
#3
Peiman Nazerian, Christian Mueller, Alexandre de Matos Soeiro, Bernd A Leidel, Sibilla Anna Teresa Salvadeo, Francesca Giachino, Simone Vanni, Karin Grimm, Múcio T Oliveira, Emanuele E Pivetta, Enrico Lupia, Stefano Grifoni, Fulvio Morello
Background -Acute aortic syndromes (AAS) are rare and severe cardiovascular emergencies with unspecific symptoms. For AAS, both misdiagnosis and over-testing are key concerns, and standardized diagnostic strategies may help physicians to balance these risks. D-dimer (DD) is highly sensitive for AAS, but is inadequate as a standalone test. Integration of pre-test probability assessment (PPA) with D-dimer (DD) testing is feasible, but the safety and efficiency of such diagnostic strategy are currently unknown...
October 13, 2017: Circulation
https://www.readbyqxmd.com/read/29022854/single-center-mid-term-experience-with-chimney-graft-technique-for-the-preservation-of-flow-to-the-supra-aortic-branches
#4
Robert Shahverdyan, Spyridon Mylonas, Michael Gawenda, Jan Brunkwall
Objectives To investigate the feasibility and the mid-term outcomes of the chimney-graft technique for the revascularization of supra-aortic branches in patients with thoracic aortic pathologies involving the aortic arch. Methods A retrospective analysis of a prospectively maintained database between January 2010 and July 2016 was performed. Primary endpoints were 30-day and overall mortality. Secondary endpoints were technical success, target vessel patency, stroke/transitory ischemic attack and type I/III endoleak rate...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/29019592/the-influence-of-allopurinol-and-post-conditioning-on-lung-injuries-induced-by-lower-limb-ischemia-and-reperfusion-in-wistar-rats
#5
Hugo Genki Kagawa Akahane, Ricardo Zanetti Gomes, Katia Sabrina Paludo, Filipe Linhares, Luana Lopes
PURPOSE: To analyze the effects of allopurinol and of post-conditioning on lung injuries induced by lower-limb ischemia and reperfusion. METHODS: Thirty rats were used. They were divided in 5 groups: (1) group A: abdominal aortic dissection only, (2) group B: ischemia and reperfusion, (3) group C: administered allopurinol (100mg/Kg) a few hours before procedure, (4) group D: post-conditioned and (5) group E: administered allopurinol and post-conditioned. With the exception of group A, all groups were submitted to infrarenal aortic ischemia for 2 hours, and reperfusion for 72 hours...
September 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28982024/alcohol-consumption-and-mortality-from-aortic-disease-among-japanese-men-the-japan-collaborative-cohort-study
#6
Toru Shirakawa, Kazumasa Yamagishi, Hiroshi Yatsuya, Naohito Tanabe, Akiko Tamakoshi, Hiroyasu Iso
BACKGROUND AND AIMS: Only a few population-based prospective studies have examined the association between alcohol consumption and abdominal aortic aneurysm, and the results are inconsistent. Moreover, no evidence exists for aortic dissection. We examined the effect of alcohol consumption on risk of mortality from aortic diseases. METHODS: A total of 34,720 men from the Japan Collaborative Cohort study, aged 40-79 years, without history of cardiovascular disease and cancer at baseline 1988 and 1990 were followed up until the end of 2009 for their mortality and its underlying cause...
September 21, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28977379/single-centre-experience-with-the-frozen-elephant-trunk-technique-in-251-patients-over-15%C3%A2-years
#7
Malakh Shrestha, Andreas Martens, Tim Kaufeld, Erik Beckmann, Sebastian Bertele, Heike Krueger, Julia Neuser, Felix Fleissner, Fabio Ius, Firas Abd Alhadi, Jasmin Hanke, Jan D Schmitto, Serghei Cebotari, Matthias Karck, Axel Haverich, Ajay Chavan
OBJECTIVES: Our goal was to present our 15-year experience (2001-2015) with the frozen elephant trunk (FET) technique. METHODS: A total of 251 patients (82 with aortic aneurysms, 96 with acute aortic dissection type A, 4 with acute type B dissections, 52 with chronic aortic dissection type A, 17 with chronic type B dissection and 67 redo cases) underwent FET implantation with either the custom-made Chavan-Haverich ( n  = 66), the Jotec E-vita ( n  = 31) or the Vascutek Thoraflex hybrid ( n  = 154) prosthesis...
August 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28974246/surgical-repair-and-reconstruction-of-aortic-arch-in-debakey-type-i-aortic-dissection-recent-advances-and-single-center-experience-in-the-application-of-branched-stent-graft
#8
Qian Zhang, Xiaochun Ma, Wenlong Zhang, Zhengjun Wang, Haizhou Zhang, Xiaofeng Zhang, Jian Song, Chengwei Zou
BACKGROUND: Aortic dissection (AD) represents a clinically uncommon aortic pathology which predicts a dismal prognosis if not promptly treated. In acute Debakey type I AD (ADIAD), aortic lesion extends from aortic root to even distal abdominal aorta among which aortic arch and its three main branches still remain a great surgical challenge for repair and reconstruction. Several decades have witnessed the painstaking efforts of cardiovascular surgeons across the globe for optimizing the surgical procedures, from total or hemi-arch replacement, "elephant trunk" technique to branched stent graft...
October 3, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28973148/a-constitutive-bcl2-down-regulation-aggravates-the-phenotype-of-pkd1-mutant-induced-polycystic-kidney-disease
#9
Laurence Duplomb, Nathalie Droin, Olivier Bouchot, Christel Robinet Thauvin, Ange-Line Bruel, Julien Thevenon, Patrick Callier, Guillaume Meurice, Noémie Pata-Merci, Romaric Loffroy, David Vandroux, Romain Da Costa, Virginie Carmignac, Eric Solary, Laurence Faivre
The main identified function of BCL2 protein is to prevent cell death by apoptosis. Mice knock-out for Bcl2 demonstrate growth retardation, severe polycystic kidney disease (PKD), gray hair and lymphopenia, and die prematurely after birth. Here, we report a 40-year-old male referred to for abdominal and thoracic aortic dissection with associated aortic root aneurysm, PKD, lymphocytopenia with a history of T cell lymphoblastic lymphoma, white hair since the age of 20, and learning difficulties. PKD, which was also detected in the father and sister, was related to an inherited PKD1 mutation...
September 11, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28965981/laparoscopic-transperitoneal-para-aortic-lymphadenectomy-in-10-steps
#10
Camille Martel-Billard, Vinciane Goillot, Alice Jacquin, Lise Lecointre, Emilie Faller, Thomas Boisramé, Jean-Jacques Baldauf, Cherif Youssef Akladios, Arnaud Wattiez
OBJECTIVE: Laparoscopic transperitoneal lymphadenectomy has a few advantages. First, it is a minimally invasive approach, and transperitoneal approach is also the best option when an intra abdominal surgery is indicated. Although the procedure was described more than two decades ago, there is a lack of diffusion of the technique. The main objective of this video is standardization and a simple description of the technique. We described this procedure in 10 logical steps which should help to understand and perform this procedure...
September 28, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28963936/experimental-and-numerical-studies-of-two-arterial-wall-delamination-modes
#11
Xiaochang Leng, Boran Zhou, Xiaomin Deng, Lindsey Davis, Susan M Lessner, Michael A Sutton, Tarek Shazly
Arterial wall dissection, which results from various pathophysiological processes, can lead to the occurrence of large area delamination in the aortic wall that can potentially block blood flow and lead to deleterious clinical conditions. Despite its critical clinical relevance, few studies have focused on investigating the failure mode of delamination in the arterial wall. In this study, we quantify the energy release rate of the medial layer of a porcine abdominal aorta via two delamination experiments: the mixed-mode delamination experiment and the "T"-shaped delamination experiment...
September 19, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28957999/medium-term-survival-after-surgery-for-acute-type-a-aortic-dissection-is-improving
#12
Christian Olsson, Anders Ahlsson, Simon Fuglsang, Arnar Geirsson, Jarmo Gunn, Emma C Hansson, Vibeke Hjortdal, Kati Jarvela, Anders Jeppsson, Ari Mennander, Shahab Nozohoor, Anders Wickbom, Igor Zindovic, Tomas Gudbjartsson
OBJECTIVES: To report long-term survival and predictors of mortality in patients included in a large, contemporary, multicentre, multinational database: Nordic Consortium for Acute Type A Aortic Dissection (NORCAAD), which consists of 8 centres in 4 Nordic countries. METHODS: Currently, NORCAAD includes 1159 patients operated between 2005 and 2014. In 30-day survivors ( n  = 955, 82%), the Kaplan-Meier and Cox proportional hazard methods were used to analyse medium-term (up to 8 years) survival and relative survival versus a matched normal population...
September 18, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28947217/management-and-evolution-of-a-wallstent-migration-in-a-paediatric-blunt-traumatic-abdominal-aortic-injury
#13
A Apodaka Diez, E Mikelarena Monteiro, Y Gallardo Hoyos, J L Fonseca Legrand
Blunt traumatic abdominal aortic injury (BTAAI) in children is a rare but severe condition. The clinical manifestation often involves other intra-abdominal visceral injuries and vertebral fractures. The best therapeutic management is still unclear with few reported endovascular cases treated. The following is the case of a 13-year-old male with an aortic abdominal dissection, spleen laceration, yeyunal contusion and haemoperitoneum after a motor vehicle collision. An endovascular approach was decided upon after progression of the intimal aortic tear...
September 22, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28939111/open-descending-thoracic-or-thoracoabdominal-aortic-approaches-for-complications-of-endovascular-aortic-procedures-19-year-experience
#14
Konstantinos Spiliotopoulos, Ourania Preventza, Susan Y Green, Matt D Price, Hiruni S Amarasekara, Brittany M Davis, Kim I de la Cruz, Scott A LeMaire, Joseph S Coselli
OBJECTIVES: Endovascular aortic repair is increasingly being used to treat aneurysms, dissections, and traumatic injuries, despite its unknown long-term durability. We describe our 19-year experience with open descending thoracic and thoracoabdominal aortic repair after endovascular aortic repair. METHODS: Between 1996 and 2015, 67 patients were treated with open distal arch, descending thoracic, or thoracoabdominal aortic repair, or extra-anatomic bypass repair with aortic extirpation for complications after endovascular repair of the thoracic (n = 45, 67%) or abdominal (n = 22, 33%) aorta...
August 26, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28932545/effects-of-preemptive-cerebrospinal-fluid-drainage-on-spinal-cord-protection-during-thoracic-endovascular-aortic-repair
#15
Seungjun Song, Suk-Won Song, Tae Hoon Kim, Kwang-Hun Lee, Kyung-Jong Yoo
BACKGROUND: Spinal cord injury (SCI) is reported to occur in 3-12% of thoracic endovascular aortic repair (TEVAR) cases, but is a potentially preventable complication of TEVAR for thoracoabdominal pathologies. Although many strategies have been devised to reduce the incidence of SCI, the effectiveness of prophylactic cerebrospinal fluid drainage (CSFD) and left subclavian artery (LSA) revascularization remains controversial. METHODS: From 2012 to 2014, 162 patients underwent TEVAR at a single institution...
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28912363/tgf%C3%AE-transforming-growth-factor-%C3%AE-blockade-induces-a-human-like-disease-in-a-nondissecting-mouse-model-of-abdominal-aortic-aneurysm
#16
Fabien Lareyre, Marc Clément, Juliette Raffort, Stefanie Pohlod, Meghana Patel, Bruno Esposito, Leanne Master, Alison Finigan, Marie Vandestienne, Nikolaos Stergiopulos, Soraya Taleb, Bram Trachet, Ziad Mallat
OBJECTIVE: Current experimental models of abdominal aortic aneurysm (AAA) do not accurately reproduce the major features of human AAA. We hypothesized that blockade of TGFβ (transforming growth factor-β) activity-a guardian of vascular integrity and immune homeostasis-would impair vascular healing in models of nondissecting AAA and would lead to sustained aneurysmal growth until rupture. APPROACH AND RESULTS: Here, we test this hypothesis in the elastase-induced AAA model in mice...
September 14, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/28898997/angiotensin-ii-infusion-into-apoe-mice-a-model-for-aortic-dissection-rather-than-abdominal-aortic-aneurysm
#17
Bram Trachet, Lydia Aslanidou, Alessandra Piersigilli, Rodrigo A Fraga-Silva, Jessica Sordet-Dessimoz, Pablo Villanueva-Perez, Marco F M Stampanoni, Nikolaos Stergiopulos, Patrick Segers
Aims: Angiotensin II-infused ApoE-/- mice are a popular mouse model for preclinical aneurysm research. Here, we provide insight in the often-reported but seldom-explained variability in shape of dissecting aneurysms in these mice. Methods and results: N = 45 excised aortas were scanned ex vivo with phase-contrast X-ray tomographic microscopy. Micro-ruptures were detected near the ostium of celiac and mesenteric arteries in 8/11 mice that were sacrificed after 3 days of angiotensin II-infusion...
August 1, 2017: Cardiovascular Research
https://www.readbyqxmd.com/read/28890304/hemodynamic-parameters-that-may-predict-false-lumen-growth-in-type-b-aortic-dissection-after-endovascular-repair-a-preliminary-study-on-long-term-multiple-follow-ups
#18
Huanming Xu, Zhenfeng Li, Huiwu Dong, Yilun Zhang, Jianyong Wei, Paul N Watton, Wei Guo, Duanduan Chen, Jiang Xiong
Thoracic endovascular aortic repair (TEVAR) is commonly applied in type-B aortic dissection. For patients with dissection affects descending aorta and extends downward to involve abdominal aorta and possibly iliac arteries, false lumen (FL) expansion might occur post-TEVAR. Predictions of dissection development may assist in medical decision on re-intervention or surgery. In this study, two patients are selected with similar morphological features at initial presentation but with different long-term FL development post-TEVAR (stable and enlarged FL)...
September 7, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28887258/case-report-severe-acute-type-b-aortic-dissection-complicated-by-acute-pancreatitis
#19
Jin Jie, Wu Yongfa, Wang Yuxin, Liao Mingfang, Qu Lefeng
A 52 year-old man presented with sudden abdominal pain and intermittent vomiting. The patient underwent contrast-enhanced computed tomography scan (CT) and was diagnosed with an acute type B aortic dissection (ABAD) involving the celiac trunk superior mesenteric artery (SMA), and extending to the renal artery. The patient was treated with thoracic endovascular aortic repair (TEVAR). After the procedure, the patient still complained of left upper abdomen abdominal pain, and an abdominal mass was detected on physical examination...
September 5, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28887246/novel-morphological-features-for-prediction-of-distal-thoracic-aortic-enlargement-after-thoracic-endovascular-aortic-repair-of-debakey-iiib-aortic-dissection
#20
Yang Yang Ge, Yan Xue, Wei Guo, Hong Peng Zhang, Xiao Ping Liu, Jiang Xiong, Xin Jia, Xiao Hui Ma, Li Jun Wang
OBJECTIVE: To assess the novel morphological features for DeBakey IIIb aortic dissection in predicting distal thoracic aortic enlargement after thoracic endovascular aortic repair (TEVAR). METHODS: Sixty-seven patients who underwent TEVAR for DeBakey IIIb aortic dissection between January 2011 and December 2013 at our center were divided based on preoperative computer tomography angiography (CTA) features into 3 groups: I (n = 27) and III (n = 9), with true and false lumen, respectively, coursing closely along thoracic vertebral bodies; and II, spiral configuration (n = 31)...
September 5, 2017: Annals of Vascular Surgery
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