keyword
MENU ▼
Read by QxMD icon Read
search

fluid structure interaction

keyword
https://www.readbyqxmd.com/read/28227065/fea-modeling-and-fluid-flow-simulation-of-human-rectum-with-inserted-bowel-catheters
#1
Yong Zhang, Tina VanRiper, Brian Rague, Drew Weidman, Yong Zhang, Tina VanRiper, Brian Rague, Drew Weidman, Tina VanRiper, Drew Weidman, Brian Rague, Yong Zhang
In this project, fluid flow and fluid-structure interaction are studied for the human lower gastrointestinal (GI) region. The study consists of two steps. First, we apply meshing methods to discretize both the human lower GI model and the catheter model at sufficient resolution suitable for importing into a Finite Element Analysis (FEA) tool. For model discretization, 3D models of the colon reconstructed from human MRI slices are used to obtain the valid inlet and outlet boundary surfaces. To resolve the viscous boundary layer in flow studies, a special structure of the near-wall volumetric mesh is built by triangular prisms that construct quasi-structured, multiple near-boundary sub-layers...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226778/simulation-of-motor-current-waveforms-in-monitoring-aortic-valve-state-during-ventricular-assist-device-support
#2
Khalid A Alonazi, Nigel H Lovell, Socrates Dokos, Khalid A Alonazi, Nigel H Lovell, Socrates Dokos, Khalid A Alonazi, Socrates Dokos, Nigel H Lovell
Monitoring of aortic valve (AV) opening and closure during left ventricular assist device (LVAD) heart pump support is crucial in preventing AV abnormalities and remodeling caused by anomalous resirculation. In this study, simulations of LVAD motor current waveforms were undertaken to investigate AV response to rotary blood pump assistance, as well as to detect AV open and close status under heart failure conditions. A two-dimensional fluid-structure interaction finite-element model is presented to predict AV state during LVAD outflow...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28220320/a-novel-method-for-non-invasively-detecting-the-severity-and-location-of-aortic-aneurysms
#3
Igor Sazonov, Ashraf W Khir, Wisam S Hacham, Etienne Boileau, Jason M Carson, Raoul van Loon, Colin Ferguson, Perumal Nithiarasu
The influence of an aortic aneurysm on blood flow waveforms is well established, but how to exploit this link for diagnostic purposes still remains challenging. This work uses a combination of experimental and computational modelling to study how aneurysms of various size affect the waveforms. Experimental studies are carried out on fusiform-type aneurysm models, and a comparison of results with those from a one-dimensional fluid-structure interaction model shows close agreement. Further mathematical analysis of these results allows the definition of several indicators that characterize the impact of an aneurysm on waveforms...
February 21, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28219008/nanoroughness-strongly-impacts-lipid-mobility-in-supported-membranes
#4
Florence Sarah Blachon, Frederic F Harb, Bogdan Munteanu, Agnès Piednoir, Remy Fulcrand, Thierry Charitat, Giovanna Fragneto, Olivier Pierre-Louis, Bernard Tinland, Jean-Paul Rieu
In vivo lipid membranes interact with rough supramolecular structures such as protein clusters and fibrils. How these features whose size ranges from a few nanometers to a few tens of nanometers impact lipid and protein mobility is still investigated. Here, we study supported phospholipid bilayers, a unique biomimetic model, deposited on etched surfaces bearing nanometric corrugations. Surface roughness and mean curvature are carefully characterized by AFM imaging using ultrasharp tips. Neutron specular reflectivity supplements this surface characterization, and indicates that the bilayers follow the large scale corrugations of the substrate...
February 20, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28215089/structure-and-property-changes-in-self-assembled-lubricin-layers-induced-by-calcium-ion-interactions
#5
George W Greene, Rajiv Thapa, Stephen Andrew Holt, Xiaoen Wang, Christopher J Garvey, Rico F Tabor
Lubricin is a "mucin-like" glycoprotein found in synovial fluids and coating the cartilage surfaces of articular joints which is now generally accepted as one of the body's primary boundary lubricants and anti-adhesive agents. Lubricin's superior lubrication and anti-adhesion are believed to derive from its unique interfacial properties by which lubricin molecules adhere to surfaces (and biomolecules, including hyaluronic acid and collagen) through discrete interactions localized to its two terminal end-domains...
February 18, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28210959/glass-transition-in-hard-core-fluids-and-beyond-using-an-effective-static-structure-in-the-mode-coupling-theory
#6
S Amokrane, F Tchangnwa Nya, J M Ndjaka
The dynamical arrest in classical fluids is studied using a simple modification of the mode coupling theory (MCT) aimed at correcting its overestimation of the tendency to glass formation while preserving its overall structure. As in previous attempts, the modification is based on the idea of tempering the static pair correlations used as input. It is implemented in this work by computing the static structure at a different state point than the one used to solve the MCT equation for the intermediate scattering function, using the pure hard-sphere glass for calibration...
February 2017: European Physical Journal. E, Soft Matter
https://www.readbyqxmd.com/read/28198901/a-nonlinear-dynamical-system-approach-for-the-yielding-behaviour-of-a-viscoplastic-material
#7
Teodor Burghelea, Miguel Moyers-Gonzalez, Raazesh Sainudiin
A nonlinear dynamical system model that approximates a microscopic Gibbs field model for the yielding of a viscoplastic material subjected to varying external stresses recently reported in R. Sainudiin, M. Moyers-Gonzalez and T. Burghelea, Soft Matter, 2015, 11(27), 5531-5545 is presented. The predictions of the model are in fair agreement with microscopic simulations and are in very good agreement with the micro-structural semi-empirical model reported in A. M. V. Putz and T. I. Burghelea, Rheol. Acta, 2009, 48, 673-689...
February 15, 2017: Soft Matter
https://www.readbyqxmd.com/read/28194537/strain-induced-inflammation-in-pulmonary-alveolar-tissue-due-to-mechanical-ventilation
#8
Parya Aghasafari, Israr Bin M Ibrahim, Ramana Pidaparti
Inflammation is the body's attempt at self-protection to remove harmful stimuli, including damaged cells, irritants, or pathogens and begin the healing process. In this study, strain-induced inflammation in pulmonary alveolar tissue under high tidal volume is investigated through a combination of an inflammation model and fluid structure interaction (FSI) analysis. A realistic three-dimensional organ model for alveolar sacs is built, and FSI is employed to evaluate strain distribution in alveolar tissue for different tidal volume (TV) values under the mechanical ventilation (MV) condition...
February 13, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28178789/corresponding-states-behavior-of-spc-e-based-modified-bent-and-hybrid-water-models
#9
Volker C Weiss
The remarkable and sometimes anomalous properties of water can be traced back at the molecular level to the tetrahedral coordination of molecules due to the ability of a water molecule to form four hydrogen bonds to its neighbors; this feature allows for the formation of a network that greatly influences the thermodynamic behavior. Computer simulations are becoming increasingly important for our understanding of water. Molecular models of water, such as SPC/E, are needed for this purpose, and they have proved to capture many important features of real water...
February 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28177574/characterization-of-protein-interactions-with-molecularly-imprinted-hydrogels-that-possess-engineered-affinity-for-high-isoelectric-point-biomarkers
#10
John R Clegg, Justin X Zhong, Afshan S Irani, Joann Gu, David S Spencer, Nicholas A Peppas
Molecularly imprinted polymers (MIPs) with selective affinity for protein biomarkers could find extensive utility as environmentally robust, cost-efficient biomaterials for diagnostic and therapeutic applications. In order to develop recognitive, synthetic biomaterials for prohibitively expensive protein biomarkers, we have developed a molecular imprinting technique that utilizes structurally similar, analogue proteins. Hydrogel microparticles synthesized by molecular imprinting with trypsin, lysozyme, and cytochrome c possessed an increased affinity for alternate high isoelectric point biomarkers both in isolation and plasma-mimicking adsorption conditions...
February 8, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28176941/bioglass-implant-coating-interactions-in-synthetic-physiological-fluids-with-varying-degrees-of-biomimicry
#11
A C Popa, G E Stan, M A Husanu, I Mercioniu, L F Santos, H R Fernandes, Jmf Ferreira
Synthetic physiological fluids are currently used as a first in vitro bioactivity assessment for bone grafts. Our understanding about the interactions taking place at the fluid-implant interface has evolved remarkably during the last decade, and does not comply with the traditional International Organization for Standardization/final draft International Standard 23317 protocol in purely inorganic simulated body fluid. The advances in our knowledge point to the need of a true paradigm shift toward testing physiological fluids with enhanced biomimicry and a better understanding of the materials' structure-dissolution behavior...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28168669/multiscale-modelling-of-bionano-interface
#12
Hender Lopez, Erik G Brandt, Alexander Mirzoev, Dmitry Zhurkin, Alexander Lyubartsev, Vladimir Lobaskin
We present a framework for coarse-grained modelling of the interface between foreign nanoparticles (NP) and biological fluids and membranes. Our model includes united-atom presentations of membrane lipids and globular proteins in implicit solvent, which are based on all-atom structures of the corresponding molecules and parameterised using experimental data or atomistic simulation results. The NPs are modelled by homogeneous spheres that interact with the beads of biomolecules via a central force that depends on the NP size...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28167603/at-home-with-mastomys-and-rattus-human-rodent-interactions-and-potential-for-primary-transmission-of-lassa-virus-in-domestic-spaces
#13
Jesse Bonwitt, Almudena Mari Sáez, Joseph Lamin, Rashid Ansumana, Michael Dawson, Jacob Buanie, Joyce Lamin, Diana Sondufu, Matthias Borchert, Foday Sahr, Elisabeth Fichet-Calvet, Hannah Brown
The multimammate mouse (Mastomys natalensis) is the reservoir for Lassa virus (LASV). Zoonotic transmission occurs when humans are directly or indirectly exposed to fluids of the multimammate mouse, such as urine, saliva, and blood. Housing characteristics and domestic organization affect rodent density in and around households and villages, and are likely to be a risk factor for Lassa fever in humans where the reservoir exists. We use semi-structured interviews (N = 51), a quantitative survey (N = 429), direct observations, and a rodent ecology study to provide new insights into how the organization of domestic spaces brings together humans and rodents and creates pathways for infection in rural settlements in Bo District, Sierra Leone...
February 6, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28159225/microwave-induced-production-of-boron-doped-hap-b-hap-and-b-hap-coated-composite-scaffolds
#14
Ekin Ö Tunçay, T Tolga Demirtaş, Menemşe Gümüşderelioğlu
The aim of the present study is to produce boron (B) doped hydroxyapatite (B-HAp), which has an osteoinductive property, and investigate in-vitro osteogenesis potential of B-HAp coated chitosan (B-HAp/Ch) scaffolds. At first, B-HAp was produced by the interaction of ions within the concentrated synthetic body fluid containing boron (B-SBF) with microwave energy. Boron incorporation into HAp structure was performed by the substitution of borate ions with phosphate and hydroxyl ions. Experiments were carried out with different microwave powers and exposure times, and optimum conditions for the production of B-HAp were determined...
March 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/28155850/integral-equation-study-of-soft-repulsive-dimeric-fluids
#15
Gianmarco Munaò, Franz Saija
We study fluid structure and water-like anomalies of a system constituted by dimeric particles interacting via a purely repulsive core-softened potential by means of integral equation theories. In our model, dimers interact through a repulsive pair potential of inverse-power form with a softened repulsion strength. By employing the Ornstein-Zernike approach and the reference interaction site model (RISM) theory, we study the behavior of water-like anomalies upon progressively increasing the elongation λ of the dimers from the monomeric case ([Formula: see text]) to the tangent configuration ([Formula: see text])...
March 22, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28155692/fluid-and-structure-coupling-analysis-of-the-interaction-between-aqueous-humor-and-iris
#16
Wenjia Wang, Xiuqing Qian, Hongfang Song, Mindi Zhang, Zhicheng Liu
BACKGROUND: Glaucoma is the primary cause of irreversible blindness worldwide associated with high intraocular pressure (IOP). Elevated intraocular pressure will affect the normal aqueous humor outflow, resulting in deformation of iris. However, the deformation ability of iris is closely related to its material properties. Meanwhile, the passive deformation of the iris aggravates the pupillary block and angle closure. The nature of the interaction mechanism of iris deformation and aqueous humor fluid flow has not been fully understood and has been somewhat a controversial issue...
December 28, 2016: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28154609/reconstruction-of-intima-and-adventitia-models-into-a-state-undeformed-by-a-catheter-by-using-ct-ivus-and-biplane-x-ray-angiogram-images
#17
Jinwon Son, Young Choi
The number of studies on blood flow analysis using fluid-structure interaction (FSI) analysis is increasing. Though a 3D blood vessel model that includes intima and adventitia is required for FSI analysis, there are difficulties in generating it using only one type of medical imaging. In this paper, we propose a 3D modeling method for accurate FSI analysis. An intravascular ultrasound (IVUS) image is used with biplane X-ray angiogram images to calculate the position and orientation of the blood vessel. However, these images show that the blood vessel is deformed by the catheter inserted into the blood vessel for IVUS imaging...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28154309/design-of-highly-dispersible-plga-microparticles-in-aqueous-fluid-for-the-development-of-long-acting-release-injectables
#18
Atsushi Nakashima, Tomohisa Izumi, Kazutomi Ohya, Keita Kondo, Toshiyuki Niwa
In this study, we developed highly dispersible polylactic glycolic acid (PLGA) copolymer microparticles (MRPs) in aqueous fluid. A solution containing both dissolved aripiprazole as a model drug and PLGA were spray-dried to make MRPs. The resultant MRPs were further co-processed with water-soluble additives and a surfactant to improve their dispersion behavior. The granules containing MRPs and additives, termed granulated microparticles (G-MRPs) were prepared by a newly established drop freeze-drying technique...
2017: Chemical & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28149943/the-apoe-%C3%AE%C2%B54-genotype-modulates-csf-ykl-40-levels-and-their-structural-brain-correlates-in-the-continuum-of-alzheimer-s-disease-but-not-those-of-strem2
#19
Juan Domingo Gispert, Gemma C Monté, Marc Suárez-Calvet, Carles Falcon, Alan Tucholka, Santiago Rojas, Lorena Rami, Raquel Sánchez-Valle, Albert Lladó, Gernot Kleinberger, Christian Haass, José Luis Molinuevo
INTRODUCTION: Among other metabolic functions, the apolipoprotein E (APOE) plays a crucial role in neuroinflammation. We aimed at assessing whether APOE ε4 modulates levels of glial cerebrospinal fluid (CSF) biomarkers and their structural cerebral correlates along the continuum of Alzheimer's disease (AD). METHODS: Brain magnetic resonance imaging (MRI) scans were acquired in 110 participants (49 control; 19 preclinical; 27 mild cognitive impairment [MCI] due to AD; 15 mild AD dementia) and CSF concentrations of YKL-40 and sTREM2 were determined...
2017: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
https://www.readbyqxmd.com/read/28149528/construction-of-physical-crosslink-based-chitosan-liquid-crystal-composite-hydrogel-and-evaluation-on-their-cytocompatibility
#20
Lin Du, Xiaohui Yang, Wenqiang Li, Xuhui Luo, Hao Wu, Jiaqing Zhang, Mei Tu
In order to provide a novel biomimetic composite substrate for tissue engineering and explore the interaction between cells and this type of material, we developed chitosan/liquid crystal (CS/LC) composite hydrogel with embedded LC phases by composing of cholesterol hydroxypropyl cellulose ester liquid crystalline material and CS. The micromorphology of CS/LC composite hydrogels exhibited 'islands-sea' phase separation structures similar to the 'fluid mosaic model' of biomembrane. In vitro cell compatibility study suggested that 3T3 is fibroblasts exhibited better initial cell adhesions and higher proliferation rates on the composite hydrogel than on the polystyrene control plate and the pure LC membrane...
February 2017: Regenerative Biomaterials
keyword
keyword
98238
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"