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fluid structure interaction

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https://www.readbyqxmd.com/read/29156541/effect-of-alumina-incorporation-on-the-surface-mineralization-and-degradation-of-a-bioactive-glass-cao-mgo-sio%C3%A2-na%C3%A2-o-p%C3%A2-o%C3%A2-caf%C3%A2-glycerol-paste
#1
Dilshat Tulyaganov, Khasan Abdukayumov, Olim Ruzimuradov, Mirabbos Hojamberdiev, Emanuel Ionescu, Ralf Riedel
This study investigates the dissolution behavior as well as the surface biomineralization in simulated body fluid (SBF) of a paste composed of glycerol (gly) and a bioactive glass in the system CaO-MgO-SiO₂-Na₂O-P₂O₅-CaF₂ (BG). The synthesis of the bioactive glass in an alumina crucible has been shown to significantly affect its bioactivity due to the incorporation of aluminum (ca. 1.3-1.4 wt %) into the glass network. Thus, the kinetics of the hydroxyapatite (HA) mineralization on the glass prepared in the alumina crucible was found to be slower than that reported for the same glass composition prepared in a Pt crucible...
November 18, 2017: Materials
https://www.readbyqxmd.com/read/29154418/measuring-non-polyaminated-lipocalin-2-for-cardiometabolic-risk-assessment
#2
Kangmin Yang, Han-Bing Deng, Andy W C Man, Erfei Song, Jialiang Zhang, Cuiting Luo, Bernard M Y Cheung, Kwok-Yung Yuen, Pia Søndergaard Jensen, Akhmadjon Irmukhamedov, Atlanta G I M Elie, Paul M Vanhoutte, Aimin Xu, Jo G R De Mey, Yu Wang
AIMS: Lipocalin-2 is a pro-inflammatory molecule characterized by a highly diversified pattern of expression and structure-functional relationships. In vivo, this molecule exists as multiple variants due to post-translational modifications and/or protein-protein interactions. Lipocalin-2 is modified by polyamination, which enhances the clearance of this protein from the circulation and prevents its excessive accumulation in tissues. On the other hand, animal studies suggest that non-polyaminated lipocalin-2 (npLcn2) plays a causal role in the pathogenesis of obesity-associated medical complications...
November 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/29151673/the-perfectly-matched-layer-absorbing-boundary-for-fluid-structure-interactions-using-the-immersed-finite-element-method
#3
Jubiao Yang, Feimi Yu, Michael Krane, Lucy T Zhang
In this work, a non-reflective boundary condition, the Perfectly Matched Layer (PML) technique, is adapted and implemented in a fluid-structure interaction numerical framework to demonstrate that proper boundary conditions are not only necessary to capture correct wave propagations in a flow field, but also its interacted solid behavior and responses. While most research on the topics of the non-reflective boundary conditions are focused on fluids, little effort has been done in a fluid-structure interaction setting...
January 2018: Journal of Fluids and Structures
https://www.readbyqxmd.com/read/29148023/fluid-structure-interaction-model-analysis-of-cerebrospinal-fluid-circulation-in-patients-with-continuous-flow-left-ventricular-assist-devices
#4
Jessica G Y Luc, Clifford A Pierre, Kevin Phan, Yashar S Vahedein, Alexander S Liberson, William K Cornwell, Steven J Phillips, Vakhtang Tchantchaleishvili
PURPOSE: The current 1-dimensional fluid structure interaction model (FSI) for understanding cerebrospinal fluid (CSF) circulation requires pulsatility as a precondition and has not been applied to patients with continuous-flow left ventricular assist devices (CF-LVAD) where pulsatility is chronically reduced. Our study aims to characterize the behavior of CSF pressure and flow in patients with CF-LVADs using a computational FSI model. METHODS: Utilizing the computational FSI model, CSF production in choroid plexuses of the 4 ventricles was specified as a boundary condition for the model...
November 16, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/29147132/numerical-investigation-of-pulse-wave-propagation-in-arteries-using-fluid-structure-interaction-capabilities
#5
Hisham Elkenani, Essam Al-Bahkali, Mhamed Souli
The aim of this study is to present a reliable computational scheme to serve in pulse wave velocity (PWV) assessment in large arteries. Clinicians considered it as an indication of human blood vessels' stiffness. The simulation of PWV was conducted using a 3D elastic tube representing an artery. The constitutive material model specific for vascular applications was applied to the tube material. The fluid was defined with an equation of state representing the blood material. The onset of a velocity pulse was applied at the tube inlet to produce wave propagation...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/29139052/a-validated-patient-specific-fsi-model-for-vascular-access-in-haemodialysis
#6
A M de Villiers, A T McBride, B D Reddy, T Franz, B S Spottiswoode
The flow rate inside arteriovenous fistulas is many times higher than physiological flow and is accompanied by high wall shear stress resulting in low patency rates. A fluid-structure interaction finite element model is developed to analyse the blood flow and vessel mechanics to elucidate the mechanisms that can lead to failure. The simulations are validated against flow measurements obtained from magnetic resonance imaging data.
November 14, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/29136310/brain-networks-of-the-imaginative-mind-dynamic-functional-connectivity-of-default-and-cognitive-control-networks-relates-to-openness-to-experience
#7
Roger E Beaty, Qunlin Chen, Alexander P Christensen, Jiang Qiu, Paul J Silvia, Daniel L Schacter
Imagination and creative cognition are often associated with the brain's default network (DN). Recent evidence has also linked cognitive control systems to performance on tasks involving imagination and creativity, with a growing number of studies reporting functional interactions between cognitive control and DN regions. We sought to extend the emerging literature on brain dynamics supporting imagination by examining individual differences in large-scale network connectivity in relation to Openness to Experience, a personality trait typified by imagination and creativity...
November 14, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29136034/a-fast-stochastic-framework-for-automatic-mr-brain-images-segmentation
#8
Marwa Ismail, Ahmed Soliman, Mohammed Ghazal, Andrew E Switala, Georgy Gimel'farb, Gregory N Barnes, Ashraf Khalil, Ayman El-Baz
This paper introduces a new framework for the segmentation of different brain structures (white matter, gray matter, and cerebrospinal fluid) from 3D MR brain images at different life stages. The proposed segmentation framework is based on a shape prior built using a subset of co-aligned training images that is adapted during the segmentation process based on first- and second-order visual appearance characteristics of MR images. These characteristics are described using voxel-wise image intensities and their spatial interaction features...
2017: PloS One
https://www.readbyqxmd.com/read/29131228/3d-printing-in-chemical-engineering-and-catalytic-technology-structured-catalysts-mixers-and-reactors
#9
REVIEW
Cesar Parra-Cabrera, Clement Achille, Simon Kuhn, Rob Ameloot
Computer-aided fabrication technologies combined with simulation and data processing approaches are changing our way of manufacturing and designing functional objects. Also in the field of catalytic technology and chemical engineering the impact of additive manufacturing, also referred to as 3D printing, is steadily increasing thanks to a rapidly decreasing equipment threshold. Although still in an early stage, the rapid and seamless transition between digital data and physical objects enabled by these fabrication tools will benefit both research and manufacture of reactors and structured catalysts...
November 13, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/29127405/atomistic-structure-of-mineral-nano-aggregates-from-simulated-compaction-and-dewatering
#10
Tuan Anh Ho, Jeffery A Greathouse, Yifeng Wang, Louise J Criscenti
The porosity of clay aggregates is an important property governing chemical reactions and fluid flow in low-permeability geologic formations and clay-based engineered barrier systems. Pore spaces in clays include interlayer and interparticle pores. Under compaction and dewatering, the size and geometry of such pore spaces may vary significantly (sub-nanometer to microns) depending on ambient physical and chemical conditions. Here we report a molecular dynamics simulation method to construct a complex and realistic clay-like nanoparticle aggregate with interparticle pores and grain boundaries...
November 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29127272/structural-integrity-of-normal-appearing-white-matter-and-sex-specific-outcomes-after-acute-ischemic-stroke
#11
Mark R Etherton, Ona Wu, Pedro Cougo, Anne-Katrin Giese, Lisa Cloonan, Kaitlin M Fitzpatrick, Allison S Kanakis, Gregoire Boulouis, Hasan H Karadeli, Arne Lauer, Jonathan Rosand, Karen L Furie, Natalia S Rost
BACKGROUND AND PURPOSE: Women have worse poststroke outcomes than men. We evaluated sex-specific clinical and neuroimaging characteristics of white matter in association with functional recovery after acute ischemic stroke. METHODS: We performed a retrospective analysis of acute ischemic stroke patients with admission brain MRI and 3- to 6-month modified Rankin Scale score. White matter hyperintensity and acute infarct volume were quantified on fluid-attenuated inversion recovery and diffusion tensor imaging MRI, respectively...
November 10, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29127067/understanding-the-structural-drivers-governing-glass-water-interactions-in-borosilicate-based-model-bioactive-glasses
#12
Nicholas Stone-Weiss, Eric M Pierce, Randall E Youngman, Ozgur Gulbiten, Nicholas J Smith, Jincheng Du, Ashutosh Goel
The past decade has witnessed a significant upsurge in the development of borate and borosilicate based resorbable bioactive glasses owing to their faster degradation rate in comparison to their silicate counterparts. However, due to our lack of understanding about the fundamental science governing the aqueous corrosion of these glasses, most of the borate/borosilicate based bioactive glasses reported in the literature have been designed by "trial-and-error" approach. With an ever-increasing demand for their application in treating a broad spectrum of non-skeletal health problems, it is becoming increasingly difficult to design advanced glass formulations using the same conventional approach...
November 7, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29125174/self-assembly-of-cubic-colloidal-particles-at-fluid-fluid-interfaces-by-hexapolar-capillary-interactions
#13
Giuseppe Soligno, Marjolein Dijkstra, René van Roij
Colloidal particles adsorbed at fluid-fluid interfaces can self-assemble, thanks to capillary interactions, into 2D ordered structures. Recently, it has been predicted by theoretical and numerical calculations [G. Soligno et al., Phys. Rev. Lett., 2016, 116, 258001] that cubes with smooth edges adsorbed at a flat fluid-fluid interface generate hexapolar capillary deformations that cause the particles to self-assemble into honeycomb and hexagonal lattices, at equilibrium and for Young's contact angle π/2. Here we extend these results...
November 10, 2017: Soft Matter
https://www.readbyqxmd.com/read/29124548/development-of-an-experimental-and-digital-cardiovascular-arterial-model-for-transient-hemodynamic-and-postural-change-studies-a-preliminary-framework-analysis
#14
Rodward L Hewlin, John P Kizito
The ultimate goal of the present work is to aid in the development of tools to assist in the treatment of cardiovascular disease. Gaining an understanding of hemodynamic parameters for medical implants allow clinicians to have some patient-specific proposals for intervention planning. In the present work an experimental and digital computational fluid dynamics (CFD) arterial model consisting of a number of major arteries (aorta, carotid bifurcation, cranial, femoral, jejunal, and subclavian arteries) were fabricated to study: (1) the effects of local hemodynamics (flow parameters) on global hemodynamics (2) the effects of transition from bedrest to upright position (postural change) on hemodynamics, and (3) diffusion of dye (medical drug diffusion simulation) in the arterial system via experimental and numerical techniques...
November 9, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/29122627/glial-function-and-dysfunction-in-the-normal-ischemic-brain
#15
REVIEW
Shino D Magaki, Christopher K Williams, Harry V Vinters
Astrocytes are the most abundant cell type in the central nervous system (CNS). Once considered to be of fairly homogeneous phenotype throughout the brain and spinal cord, they are now understood to be heterogeneous in both structure and function. They are important in brain functions as diverse as ion and fluid balance in the interstitial space, contributing to integrity of the neurovascular unit (blood-brain barrier), neurotransmitter regulation, metabolism of energy substrates and possibly even axonal regeneration...
November 6, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29120962/endothelial-factors-in-the-pathogenesis-and-treatment-of-chronic-kidney-disease-part-i-general-mechanisms-a-joint-consensus-statement-from-the-european-society-of-hypertension-working-group-on-endothelin-and-endothelial-factors-and-the-japanese-society-of-hypertension
#16
Gian Paolo Rossi, Teresa M Seccia, Matthias Barton, A H Jan Danser, Peter W de Leeuw, Neeraj Dhaun, Damiano Rizzoni, Patrick Rossignol, Luis-Miguel Ruilope, Anton H van den Meiracker, Sadayoshi Ito, Naoyuki Hasebe, David J Webb
: Kidney damage is a common consequence of arterial hypertension, but is also a cause of atherogenesis. Dysfunction and/or harm of the endothelium in glomeruli and tubular interstitium damage the function of these structures and translates into dynamic changes of filtration fraction, with progressive reduction in glomerular filtration rate, expansion of extracellular fluid volume, abnormal ion balance, and hypoxia, ultimately leading to chronic kidney disease. Considering the key role played by endothelial dysfunction in chronic kidney disease, the Working Group on Endothelin and Endothelial Factors of the European Society of Hypertension and the Japanese Society of Hypertension have critically reviewed available knowledge on the mechanisms underlying endothelial cell injury...
November 7, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/29119728/a-framework-for-designing-patient-specific-bioprosthetic-heart-valves-using-immersogeometric-fluid-structure-interaction-analysis
#17
Fei Xu, Simone Morganti, Rana Zakerzadeh, David Kamensky, Ferdinando Auricchio, Alessandro Reali, Thomas J R Hughes, Michael S Sacks, Ming-Chen Hsu
Numerous studies have suggested that medical image derived computational mechanics models could be developed to reduce mortality and morbidity due to cardiovascular diseases by allowing for patient-specific surgical planning and customized medical device design. In this work, we present a novel framework for designing prosthetic heart valves using a parametric design platform and immersogeometric fluid-structure interaction (FSI) analysis. We parameterize the leaflet geometry using several key design parameters...
November 9, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29118121/hiv-1-r5-macrophage-tropic-envelope-glycoprotein-trimers-bind-cd4-with-high-affinity-while-the-cd4-binding-site-on-non-macrophage-tropic-t-tropic-r5-envelopes-is-occluded
#18
Briana Quitadamo, Paul J Peters, Alexander Repik, Olivia O'Connell, Zhongming Mou, Matthew Koch, Mohan Somasundaran, Robin Brody, Katherine Luzuriaga, Aaron Wallace, Shixia Wang, Shan Lu, Sean McCauley, Jeremy Luban, Maria Duenas-Decamp, Maria Paz Gonzalez-Perez, Paul Clapham
HIV-1 R5 viruses exploit CCR5 as a coreceptor to infect both T-cells and macrophages. R5 viruses that are transmitted or derived from immune tissue and peripheral blood are mainly inefficient at mediating infection of macrophages. In contrast, highly macrophage-tropic R5 viruses predominate in brain tissue and can be detected in cerebral spinal fluid, but are infrequent in immune tissue or blood even in late disease. These mac-tropic R5 variants carry envelope glycoproteins (Envs) adapted to exploit low levels of CD4 on macrophages to induce infection...
November 8, 2017: Journal of Virology
https://www.readbyqxmd.com/read/29113079/synthesis-of-ferrofluids-made-of-iron-oxide-nanoflowers-interplay-between-carrier-fluid-and-magnetic-properties
#19
Federico Spizzo, Paolo Sgarbossa, Elisabetta Sieni, Alessandra Semenzato, Fabrizio Dughiero, Michele Forzan, Roberta Bertani, Lucia Del Bianco
Ferrofluids are nanomaterials consisting of magnetic nanoparticles that are dispersed in a carrier fluid. Their physical properties, and hence their field of application are determined by intertwined compositional, structural, and magnetic characteristics, including interparticle magnetic interactions. Magnetic nanoparticles were prepared by thermal decomposition of iron(III) chloride hexahydrate (FeCl₃·6H₂O) in 2-pyrrolidone, and were then dispersed in two different fluids, water and polyethylene glycol 400 (PEG)...
November 5, 2017: Nanomaterials
https://www.readbyqxmd.com/read/29107725/proximal-stenosis-is-associated-with-rupture-status-in-middle-cerebral-artery-aneurysms
#20
Alexei Antonov, Kenichi Kono, Kilian Greim-Kuczewski, James E Hippelheuser, Alexandra Lauric, Adel M Malek
BACKGROUND: Hemodynamic factors impact cerebral aneurysm development and progression. Parent vessel architectural features, such as caliber, curvature and angle can affect downstream pressure and shear stress. OBJECTIVE: Investigate the association between proximal parent vessel stenosis and aneurysm rupture status at the middle cerebral artery (MCA) bifurcation. METHODS: Catheter 3D rotational angiographic datasets from 69 Japanese patients with MCA aneurysms (58 unruptured/11 ruptured) were analyzed...
October 28, 2017: World Neurosurgery
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