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https://www.readbyqxmd.com/read/28635981/patient-perceived-access-to-care-when-actively-seeking-treatment
#1
Zachary Pruitt, Susan Sportsman
PURPOSE/OBJECTIVES: To examine predictors of perceived access to care and reported barriers to care of patients with cancer actively seeking treatment.
. DESIGN: Retrospective secondary data analysis.
. SETTING: U.S. Medical Expenditure Panel Survey, a national survey with questions about healthcare coverage and access.
. SAMPLE: 1,170 adults with cancer actively seeking treatment.
. METHODS: A retrospective analysis of data...
May 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28635555/personality-disorders-patient-characteristics-and-level-of-outpatient-treatment-service
#2
Sebastian Simonsen, Torben Heinskou, Per Sørensen, Sofie Folke, Marianne Engelbrecht Lau
BACKGROUND: In this naturalistic study, patients with personality disorders (N = 388) treated at Stolpegaard Psychotherapy Center, Mental Health Services, Capital Region of Denmark were allocated to two different kinds of treatment: a standardized treatment package with a preset number of treatment hours (basic hospital service) and 2: a specialized treatment program for the most severely affected patients without a predetermined restricted number of treatment hours and significantly more individual psychotherapy (regional specialized hospital services)...
February 13, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28633106/selective-photocytotoxicity-of-anthrols-on-cancer-stem-like-cells-the-effect-of-quinone-methides-or-reactive-oxygen-species
#3
Lidija Uzelac, Đani Škalamera, Kata Mlinarić-Majerski, Nikola Basarić, Marijeta Kralj
Cancer stem cells (CSCs) are a subpopulation of cancer cells that share properties of embryonic stem cells like pluripotency and self-renewal and show increased resistance to chemo- and radiotherapy. Targeting CSC, rather than cancer cells in general, is a novel and promising strategy for cancer treatment. Novel therapeutic approaches, such as photodynamic therapy (PDT) have been investigated. A promising group of phototherapeutic agents are reactive intermediates - quinone methides (QMs). This study describes preparation of QM precursor, 2-hydroxy-3-hydroxymethylanthracene (2) and a detailed photochemical and photobiological investigation on similar anthracene derivatives 3 and 4...
June 3, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28632867/effect-of-an-internet-based-program-on-weight-loss-for-low-income-postpartum-women-a-randomized-clinical-trial
#4
Suzanne Phelan, Todd Hagobian, Anna Brannen, Karen E Hatley, Andrew Schaffner, Karen Muñoz-Christian, Deborah F Tate
Importance: Postpartum weight retention increases lifetime risk of obesity and related morbidity. Few effective interventions exist for multicultural, low-income women. Objective: To test whether an internet-based weight loss program in addition to the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC program) for low-income postpartum women could produce greater weight loss than the WIC program alone over 12 months. Design, Setting, and Participants: A 12-month, cluster randomized, assessor-blind, clinical trial enrolling 371 adult postpartum women at 12 clinics in WIC programs from the California central coast between July 2011 and May 2015 with data collection completed in May 2016...
June 20, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28632093/allergic-contact-dermatitis-from-ophthalmics
#5
Yue Zheng, Paru R Chaudhari, Howard I Maibach
In this article we summarize the recently described allergens responsible for allergic contact dermatitis due to ophthalmic drugs and contact lens solutions, and emphaage the need on how to perform diagnostic testing in this special clinical entity.
March 6, 2017: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/28632075/-is-marijuana-even-a-drug-a-qualitative-study-of-how-teens-view-marijuana-use-and-why-they-use-it
#6
Bettina Friese
This qualitative study examines how youth in the San Francisco Bay Area perceive marijuana and their motives for using or not using marijuana. Current regular users were more likely to perceive marijuana smoking as an enjoyable activity, comparable to a hobby or sport. Current occasional users commonly reported smoking marijuana when it was offered to them, on special occasions, and sometimes as a result of not wanting to be left out. Most former regular users reported quitting marijuana use due to getting into trouble, being ordered into drug treatment and/or being drug tested...
February 26, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28631828/development-of-a-colloidal-gold-immunochromatographic-assay-gica-for-the-rapid-detection-of-spiroplasma-eriocheiris-in-commercially-exploited-crustaceans-from-china
#7
H Liu, Y Xiu, Y Xu, M Tang, S Li, W Gu, Q Meng, W Wang
Spiroplasma eriocheiris is an emerging pathogen in freshwater crustaceans. In recent years, Eriocheir sinensis, Procambarus clarkii, Litopenaeus vannamei, Macrobrachium rosenbergii and Macrobrachium nipponense had been infected by this pathogen in China. An immunochromatographic strip test using gold nanoparticles was developed for rapidly detecting this pathogen. The strip test based on the principle of sandwich immunoassay by the specific combination between the pathogen and polyclonal antibody on a nitrocellulose membrane...
June 20, 2017: Journal of Fish Diseases
https://www.readbyqxmd.com/read/28631692/-multidisciplinary-problems-of-rheumatology-and-pulmonology
#8
L P Ananyeva
Damage to the respiratory system worsens prognosis and increases mortality in all systemic immunoinflammatory rheumatic diseases (SIRDs). Leading pulmonary manifestations in each disease are different, so the typical picture of each nosological entity is very peculiar. In all SIRDs, the disease starts with lung involvement in 10-20% of cases, preceding the expanded clinical presentation of a systemic disease. At a certain stage, lung damage may be the only manifestation of the disease or predominate in its clinical picture, determining the severity of a condition...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28631328/phenotypic-characterisation-of-coagulase-negative-staphylococci-isolated-from-blood-cultures-in-newborn-infants-with-a-special-focus-on-staphylococcus-capitis
#9
Gustaf Ehlersson, Bengt Hellmark, Olov Svartström, Bianca Stenmark, Bo Söderquist
AIM: This Swedish study determined which species of coagulase-negative staphylococci (CoNS) were found in neonatal blood cultures and whether they included Staphylococcus capitis clones with decreased susceptibility to vancomycin. METHODS: CoNS isolates (n=332) from neonatal blood cultures collected at Örebro University Hospital during 1987-2014 were identified to species level with matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF MS)...
June 20, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28631124/toxicity-evaluation-of-cypermethrin-glyphosate-and-malathion-on-two-indigenous-zooplanktonic-species
#10
Carlos Vicente Garza-León, Mario Alberto Arzate-Cárdenas, Roberto Rico-Martínez
In Aguascalientes, Mexico, there is a special concern about pesticides because of their intensive use on guava production areas, which are located in the vicinity of water reservoirs; thus, non-target organisms could be exposed. Thereafter, the aim of this work was to assess the effect of cypermethrin, Faena® (glyphosate), and malathion, which are the most used pesticides in Aguascalientes' guava production, on the indigenous freshwater species Alona guttata (cladoceran) and Lecane papuana (rotifer). Acute 48-h toxicity tests were carried out, and LC50 values were calculated...
June 19, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28630257/contrasting-effects-of-medial-and-lateral-orbitofrontal-cortex-lesions-on-credit-assignment-and-decision-making-in-humans
#11
MaryAnn P Noonan, Bolton Chau, Matthew Fs Rushworth, Lesley K Fellows
The orbitofrontal cortex is critical for goal-directed behavior. Recent work in macaques has suggested the lateral orbitofrontal cortex (lOFC) is relatively more concerned with assignment of credit for rewards to particular choices during value-guided learning, while the medial orbitofrontal cortex (often referred to as ventromedial prefrontal cortex in humans; vmPFC/mOFC) is involved in constraining the decision to the relevant options. We examined whether people with damage restricted to sub-regions of prefrontal cortex showed the patterns of impairment observed in prior investigations of the effects of lesions to homologous regions in macaques...
June 19, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28629555/evaluating-the-ability-to-detect-pancreatic-lesions-using-a-special-ultrasonography-examination-focusing-on-the-pancreas
#12
Miho Nakao, Kazuhiro Katayama, Junko Fukuda, Suetsumi Okagaki, Kozo Misu, Sayako Miyazaki, Noritoshi Matsuno, Reiko Ashida, Tatsuya Ioka, Yuri Ito, Kazuyoshi Ohkawa
PURPOSE: The ability to detect pancreatic cysts was compared between special ultrasonography (US) examination focusing on the pancreas (special pancreatic US) and routine upper abdominal ultrasonography to objectively assess the ability of the former to detect cysts. SUBJECTS AND METHODS: Of 3704 patients who underwent special pancreatic US at our hospital, 186 underwent routine upper abdominal US within six months, had pancreatic cysts, and underwent magnetic resonance imaging (MRI)...
June 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28629163/%C3%AE-cyanoalanine-synthases-and-their-possible-role-in-pierid-host-plant-adaptation
#13
Anna-Maria Herfurth, Maike van Ohlen, Ute Wittstock
Cyanide is generated in larvae of the glucosinolate-specialist Pieris rapae (Lepidoptera:Pieridae) upon ingestion of plant material containing phenylalanine-derived glucosinolates as chemical defenses. As these glucosinolates were widespread within ancient Brassicales, the ability to detoxify cyanide may therefore have been essential for the host plant shift of Pierid species from Fabales to Brassicales species giving rise to the Pierinae subfamily. Previous research identified β-cyanoalanine and thiocyanate as products of cyanide detoxification in P...
June 18, 2017: Insects
https://www.readbyqxmd.com/read/28628800/increased-internal-femoral-torsion-can-be-regarded-as-a-risk-factor-for-patellar-instability-a-biomechanical-study
#14
Peter Kaiser, Werner Schmoelz, Philip Schoettle, Marit Zwierzina, Christian Heinrichs, Rene Attal
BACKGROUND: Increased internal femoral torsion is regarded as a risk factor for patellar instability. Biomechanical investigations confirming this hypothesis are missing. METHODS: Eight fresh-frozen cadaver knees were tested on a specially designed simulator. Patellar motion and patellofemoral pressure were evaluated for 0°, 10°, and 20° of increased internal and external femoral torsion with native and with transected medial patellofemoral ligaments used to simulate patellar instability...
June 10, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28628480/kernel-based-measure-of-variable-importance-for-genetic-association-studies
#15
Vicente Gallego, M Luz Calle, Ramon Oller
The identification of genetic variants that are associated with disease risk is an important goal of genetic association studies. Standard approaches perform univariate analysis where each genetic variant, usually Single Nucleotide Polymorphisms (SNPs), is tested for association with disease status. Though many genetic variants have been identified and validated so far using this univariate approach, for most complex diseases a large part of their genetic component is still unknown, the so called missing heritability...
June 17, 2017: International Journal of Biostatistics
https://www.readbyqxmd.com/read/28628021/correlation-between-spirometry-dates-and-special-allergen-specific-ige-in-patients-with-bronchial-asthma-in-west-georgia
#16
R Sepiashvili, M Chikhladze, D Khachapuridze, S Gamkrelidze
The study aimed to establish correlation between airway obstruction and specific IgE specificity, managing future treatment in the patients with bronchial asthma, among the population of west Georgia. In the study have been involved 56 patients (among them 24 males and 32 females) of different ages, with diagnostic bronchial asthma (according to GINA recommendation). On the ground of the aim the study included the following steps of allegro-diagnostics: I step - Computerized spirometry by apparatus ,,SPIROLAB 3"...
May 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28627411/impact-of-procedural-training-on-pregnancy-outcomes-and-career-satisfaction-in-female-post-graduate-medical-trainees-in-the-united-states
#17
Jennifer S Davids, Rebecca E Scully, Nelya Melnitchouk
BACKGROUND: Compared to non-procedural fields, procedural specialization requires longer training, less flexible schedules, and greater physical demands. The impact of these factors on pregnancy, maternity outcomes, and career satisfaction has not been well described. STUDY DESIGN: Data were gathered from 738 United States postgraduate medical trainee mothers via an anonymous, IRB-approved online survey. Univariate analysis was performed using Chi-squared tests...
June 13, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28626361/molecular-biomarkers-of-colorectal-cancer-and-cancer-disparities-current-status-and-perspective
#18
Upender Manne, Trafina Jadhav, Balananda-Dhurjati Kumar Putcha, Temesgen Samuel, Shivani Soni, Chandrakumar Shanmugam, Esther A Suswam
This review provides updates on the efforts for the development of prognostic and predictive markers in colorectal cancer based on the race/ethnicity of patients. Since the clinical consequences of genetic and molecular alterations differ with patient race and ethnicity, the usefulness of these molecular alterations as biomarkers needs to be evaluated in different racial/ethnic groups. To accomplish personalized patient care, a combined analysis of multiple molecular alterations in DNA, RNA, microRNAs (miRNAs), metabolites, and proteins in a single test is required to assess disease status in a precise way...
December 2016: Current Colorectal Cancer Reports
https://www.readbyqxmd.com/read/28625988/modification-of-a-pollen-trap-design-to-capture-airborne-conidia-of-entomophaga-maimaiga-and-detection-by-quantitative-pcr
#19
Tonya D Bittner, Ann E Hajek, Andrew M Liebhold, Harold Thistle
The goal of this study was to develop effective and practical field sampling methods for quantifying aerial deposition of airborne conidia of Entomophaga maimaiga over space and time. This important fungal pathogen is a major cause of larval mortality in invasive gypsy moth (Lymantria dispar) populations in the United States. Airborne conidia of this pathogen are relatively large (similar in size to pollen) with unusual characteristics, requiring specialized methods for collection and quantification. Initially, dry sampling (settling of spores from the air onto a dry surface) was used to confirm the detectability of E...
June 16, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28625936/do-medical-french-students-know-how-to-properly-score-a-mini-mental-state-examination
#20
Intza Hernandorena, Sophie Chauvelier, Jean-Sébastien Vidal, Matthieu Piccoli, Joséphine Coulon, Laurence Hugonot-Diener, Anne-Sophie Rigaud, Olivier Hanon, Emmanuelle Duron
The mini mental state examination (MMSE) is a validated tool to assess global cognitive function. Training is required before scoring. Inaccurate scoring can lead to inappropriate medical decisions. In France, MMSE is usually scored by medical students. To assess if medical French students know how to properly score a mini mental state examination. Two « physician-patient » role playings performed by 2 specialized physicians, were performed in front of University Paris V medical students. Role playing A: Scoring of a MMSE according to a script containing five tricks; Role playing B: Find the 5 errors committed in a pre-filled MMSE form, according to the second script...
June 1, 2017: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
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