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Vit E

Jae Cheol Kim, Bruce P Mullan, John L Black, Robert J E Hewitt, Robert J van Barneveld, John R Pluske
BACKGROUND: This experiment was conducted to test the hypothesis that vitamin E (Vit E) and acetylsalicylic acid (ASA), a cyclooxygenase-2 (COX-2) inhibitor, will additively reduce the production of the immunosuppressive molecule prostaglandin E2 (PGE2) and hence reduce inflammatory responses in weaner pigs experimentally infected with an enterotoxigenic strain of E. coli. METHODS: The experiment was conducted in a research facility with 192 individually-housed male weaner pigs (Landrace × Large White) weighing 6...
2016: Journal of Animal Science and Biotechnology
Parmida Beigi, Paul Malenfant, Abtin Rasoulian, Robert Rohling, Alison Dube, Vit Gunka
Current 2-D ultrasound technology is unable to perform a midline neuraxial needle insertion under real-time ultrasound guidance using a standard needle and without an assistant. The aim of the work described here was to determine the feasibility of a new technology providing such capability, starting with a study evaluating the selected puncture site. A novel 3-D ultrasound imaging technique was designed using thick-slice rendering in conjunction with a custom needle guide (3DUS + Epiguide). A clinical feasibility study evaluated the ability of 3DUS + Epiguide to identify the epidural needle puncture site for a midline insertion in the lumbar spine...
October 6, 2016: Ultrasound in Medicine & Biology
Anne Mößeler, Marion Schmicke, Martin Höltershinken, Martin Beyerbach, Josef Kamphues
Pancreatic exocrine insufficiency (PEI) is a disease of diverse aetiology-e.g., majority of patients suffering from cystic fibrosis (CF) show PEI congenitally. Malnutrition and malabsorption of nutrients impair growth and nutritional status. As reduced fat digestion leads to a deficiency of fat-soluble vitamins the supplementation is standard, but absorption is a critical point in PEI-patients. The pancreatic duct ligated (PL) pig is an established model for PEI in humans and has been proven to be a suitable model to compare different vitamin additives for supplementation...
2016: International Journal of Molecular Sciences
Abdulrahman Khazim Al-Asmari, Abdul Quaiyoom Khan, Sarah A Al-Asmari, Abdulqadir Al-Rawi, Saud Al-Omani
BACKGROUND: Intestinal mucositis is a major concern related with cancer therapy. It is well established that overproduction of reactive oxygen species and inflammatory mediators plays vital role in the pathogenesis of mucositis. The aim of the study was to investigate the modulatory effect of vitamin E (vit. E) on 5-fluorouracil (5-FU)-induced intestinal mucositis by targeting oxidative stress and inflammatory markers in rats. METHODS: Rats were randomly divided into four groups of six animals each...
September 2, 2016: Journal of Complementary & Integrative Medicine
Fatma I Abo El-Ela, S A S Shany, Manal B El-Deen, H A El-Banna, A A El-Gendy, K Hendy, M A Tohamy
Tylvalosin (TVS) is a third-generation macrolide drug used for prophylaxis and treatment of mycoplasma, however; it is supposed to possess an immunosuppressive effect. In the current study, the immunosuppressive effect of TVS and florfenicol (FFC) and the potential immunomodulatory role of Vit E were investigated. The experiment included one day old chick groups treated with either TVS, FFC, Vit E, TVS/Vit E, FFC/Vit E and control non-treated group. Chicks were vaccinated with inactivated H9N2 avian influenza (AI) vaccine and humoral antibody titers to viral antigen as well as innate immunity (serum lysozyme activity and nitric oxide levels) were evaluated...
October 2016: Research in Veterinary Science
Soroush Safa, Gholamali Moghaddam, Raziallah Jafari Jozani, Hossein Daghigh Kia, Hossein Janmohammadi
This study was conducted to determine the combined effects of adding vitamin E (VitE) and selenium nanoparticle (Nano-Se) as antioxidant supplements to rooster semen extender for freezing. Semen samples were collected from 12 White Leghorn roosters and pooled. Subsequently, the samples were divided into nine equal groups using modified Beltsville extender. Extenders were supplemented with either two amounts of VitE (5 and 10μg/mL) or two amounts of Nano-Se (1% and 2%) or a combination of both VitE and Nano-Se, and no antioxidants extender (control group)...
September 15, 2016: Animal Reproduction Science
Jirakrit Leelarungrayub, Araya Yankai, Decha Pinkaew, Rungthip Puntumetakul, James J Laskin, Richard J Bloomer
OBJECTIVE: The aims of this preliminary study were to evaluate the antioxidant and lipid status before and after star fruit juice consumption in healthy elderly subjects, and the vitamins in star fruit extracts. METHODS: A preliminary designated protocol was performed in 27 elderly individuals with a mean (±SD) age of 69.5±5.3 years, by planning a 2-week control period before 4 weeks of consumption of star fruit twice daily. Oxidative stress parameters such as total antioxidant capacity, glutathione, malondialdehyde, protein hydroperoxide, multivitamins such as l-ascorbic acid (Vit C), retinoic acid (Vit A), and tocopherol (Vit E), and the lipid profile parameters such as cholesterol, triglyceride, high-density lipoprotein-cholesterol (HDL-C) and low-density lipoprotein-cholesterol (LDL-C) were analyzed...
2016: Clinical Interventions in Aging
Milan Balaz, Radek Jupa, Steven Jansen, Alexander Cobb, Vít Gloser
Vessels with simple perforation plates, found in the majority of angiosperms, are considered the evolutionarily most advanced conduits, least impeding the xylem sap flow. Nevertheless, when measured, their hydraulic resistivity (R, i.e., inverse value of hydraulic conductivity) is significantly higher than resistivity predicted using Hagen-Poiseuille equation (RHP). In our study we aimed (i) to quantify two basic components of the total vessel resistivity - vessel lumen resistivity and end wall resistivity, and (ii) to analyze how the variable inner diameter of the vessel along its longitudinal axis affects resistivity...
September 8, 2016: Tree Physiology
Mostafa A Darwish, Amira M Abo-Youssef, Marwa M Khalaf, Ali A Abo-Saif, Ibrahim G Saleh, Tamer M Abdelghany
Cisplatin (CP) is one of the most effective chemotherapeutic agents. Unfortunately, CP-induced nephrotoxicity hampered its use. This study aims to investigate the effect of vitamin E (Vit E) on CP-induced nephrotoxicity. Male white albino rats were divided to four group's six rats each and received either, 1% tween 80 in normal saline or Vit E (75 mg/kg) per day for 14 consecutive days or a single injection of CP (6 mg/kg) alone or CP (6 mg/kg) together with Vit E (75 mg/kg per day for 14 consecutive days)...
August 23, 2016: Journal of Biochemical and Molecular Toxicology
Karol Krak, Petr Vít, Alexander Belyayev, Jan Douda, Lucia Hreusová, Bohumil Mandák
Reticulate evolution is characterized by occasional hybridization between two species, creating a network of closely related taxa below and at the species level. In the present research, we aimed to verify the hypothesis of the allopolyploid origin of hexaploid C. album s. str., identify its putative parents and estimate the frequency of allopolyploidization events. We sampled 122 individuals of the C. album aggregate, covering most of its distribution range in Eurasia. Our samples included putative progenitors of C...
2016: PloS One
C Souza, T C Santos, A E Murakami, L C V Iwaki, J F Mello
The aim of this study was to evaluate the effect of dietary supplementation of vitamin K (vit K) and Ca in the diets of laying hens on bone and blood parameters and performance during the growing phase and the effects on the laying phase up to 32 weeks. The study utilized 120 Hy-Line W-36 pullets in the growing phase (13-18 weeks), 80 laying hens in the production phase (20-32 weeks), distributed in a completely randomized design in a 2 × 5 factorial arrangement, two levels of Ca (0.8 and 1.4%) and five levels of vit K supplementation (0, 2, 8, 16 and 32 mg/kg) with four experimental units...
July 20, 2016: Journal of Animal Physiology and Animal Nutrition
Haikuo Xue, Huijun Ren, Lei Zhang, Xiaoxu Sun, Wanhai Wang, Shijie Zhang, Junwei Zhao, Liang Ming
OBJECTIVES: Multiple sclerosis (MS) is a serious neurological autoimmune disease, it commonly affects young adults. Vitamin E (Vit E) is an important component of human diet with antioxidant activity, which protects the body's biological systems. In order to assess the effect of Vit E treatment on this autoimmune disease, we established experimental autoimmune encephalomyelitis (EAE), the animal model of MS, and treated EAE with α-tocopherol (AT) which is the main content of Vit E. MATERIALS AND METHODS: Twenty C57BL/6 adult female mice were used and divided into two groups randomly...
May 2016: Iranian Journal of Basic Medical Sciences
Busra Burcu, Mehmet Kanter, Zeynep Nur Orhon, Oguzhan Yarali, Rukiye Karabacak
OBJECTIVE: To investigate the possible protective effects of Vitamin E (Vit E) on oxidative stress and jejunal damage in the rat intestinal mucosa after methotrexate (MTX)-induced enterotoxicity. STUDY DESIGN: Rats were divided into 3 groups: control, MTX, and MTX+ Vit E; each group contained 8 animals. The control group was given physiological serum in addition to sunflower oil for 3 days. The second group was given sunflower oil with intragastric tube daily, followed by MTX injection (20 mg/kg intraperitoneally)...
April 2016: Analytical and Quantitative Cytopathology and Histopathology
Florian J Wegehaupt, Nancy Lunghi, Vanessa M G Hogger, Thomas Attin
The extrinsic sources for erosion-causing acids are primarily acidic beverages and foodstuffs. Effervescent tablets also contain organic acids (e.g. citric, tartaric, malic) in order to form carbon dioxide by contact with water – with the help of the carbonate salts of the tablets. To adequately inform patients about the possible erosive potential of effervescent tablets, this study was undertaken in order to investigate the erosive potential of effervescent tablets (ET), containing either a combination of vitamins and minerals or vitamins only, commercially available in Switzerland...
2016: Swiss Dental Journal
Halil Ozkol, Gulay Bulut, Ragıp Balahoroglu, Yasin Tuluce, Hatice Uce Ozkol
The aim of this study was to determine possible protective influences of selenium (Se), N-acetylcysteine (NAC), and vitamin E (Vit E) against acute ethanol (EtOH) intoxication. Thirty-six rats were divided into six groups: I (control), II (EtOH), III (EtOH + Se), IV (EtOH + Vit E), V (EtOH + NAC), and VI (EtOH + mix). Except group I, EtOH was given the other pretreated (groups III, IV, V, and VI) and untreated groups (group II). Compared with the EtOH group, serum aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, lactate dehydrogenase, creatine kinase, and creatine kinase-MB levels were significantly decreased in all pretreated groups, whereas slightly diminished amylase and lipase were observed...
June 1, 2016: Biological Trace Element Research
Giorgia Vici, Luca Belli, Massimiliano Biondi, Valeria Polzonetti
BACKGROUND & AIMS: The only available treatment for celiac disease (CD) is lifelong adherence to gluten free (GF)-diet. However, GF-diet may lead to possible nutrient unbalance resulting in improper nutritional quality of diet. The aim of this study is to evaluate the nutritional quality of GF-diet. METHODS: MEDLINE(®)/PubMed and Cochrane Library were electronically searched for articles published between 1990/01/01 and 2015/09/01. RESULTS: GF-diet was found to be poor in alimentary fiber due in particular to the necessary avoidance of several kinds of foods naturally rich in fiber (i...
May 7, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
Mahmoud Abdelghaffar Emam, Mahmoud E A Abouelroos, Fatma A Gad
Uteri of mature Egyptian buffalo cows (5-10 years old) were collected at follicular (n=12) and luteal (n=16) phases of estrous cycle to investigate the expression of calbindin-D9k (CaPB-9k) and vitamin D receptor (VDR). This study was done using avidin-biotin immunohistochemistry method. In addition, blood levels of calcium (Ca), vitamin D3 (Vit D), estrogen (E2) and progesterone (P4) were measured. The immunohistochemical findings restricted the expressions of CaBP-9k and VDR to the luminal and glandular epithelia of the endometrium implicating the importance of CaBP-9K and VDR in the function of endometrial epithelium, especially the glandular one, in order to prepare a receptive uterus...
June 2016: Acta Histochemica
Rukh-e-Nasreen Agha, Aftab Saeed, Halima Nazar
The objective of the study was to undertake evidence-base study to evaluate clinical manifestation of the over-estimated use of herbal drug Plantago ovata and to compare it with placebo for the efficacy and adverse effects. The patients of both genders were included. Blood urea, creatinine, ALT, Serum B12, CP, ESR and liver function tests were performed. The data was statistically analyzed in both groups for differential symptomatology. In anorexia test verses control results showed that Plantago ovata husk and placebo showed the affected ratio as 81 percent and 50 percent, correspondingly...
March 2016: Pakistan Journal of Pharmaceutical Sciences
David J Gifondorwa, Tyran D Thompson, June Wiley, Alexander E Culver, Pamela K Shetler, Guilherme V Rocha, Yanfei L Ma, Venkatesh Krishnan, Henry U Bryant
INTRODUCTION: There is evidence that supports a role for Vitamin D (Vit. D) in muscle. The exact mechanism by which Vit. D deficiency impairs muscle strength and function is not clear. METHODS: Three-week-old mice were fed diets with varied combinations of Vit. D and Ca(2+) deficiency. Behavioral testing, genomic and protein analysis, and muscle histology were performed with a focus on neuromuscular junction (NMJ)-related genes. RESULTS: Vit...
April 13, 2016: Muscle & Nerve
Mritunjay Kumar, Bhabatosh Pal, R D Purkayastha, Joybrath Roy
The objective of the present study was to investigate the clinico-pathological changes and therapeutic evaluation of gamma-benzene hexachloride and cetrimide along with vit A, D3, E and H in Black Bengal goat infested Psoroptes cuniculi mange. The study was conducted on 14 Black Bengal goats; 6 clinically infested with Psoroptes mange (group I) and 8 healthy goats (group II). Haemato-biochemical profile viz., haemoglobulin concentration, packed cell volume, total leukocyte count, albumin and albumin globulin ratio revealed significantly (P < 0...
March 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
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