keyword
MENU ▼
Read by QxMD icon Read
search

ende

keyword
https://www.readbyqxmd.com/read/28454195/-unicompartmental-vs-total-knee-arthroplasty-for-medial-osteoarthritis
#1
Tilman Pfitzner, Carsten Perka, Philipp von Roth
Background In end-stage medial osteoarthritis, the surgeon can decide whether to use unicompartmental or total knee arthroplasty for operative treatment of the patient. Despite the available literature there is a lack of evidence to suggest if one procedure can be rated as being superior to the other. With increasing demand for knee arthroplasty, treatment with the highest expectation of success will be of particular interest. The purpose of this manuscript was to analyse and compare the available literature on unicompartmental vs...
April 28, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28454187/combination-of-transforaminal-and-interlaminar-percutaneous-endoscopic-lumbar-diskectomy-for-extensive-down-migrated-disk-herniation
#2
Kyung-Chul Choi, Jung Hyun Lee, Jin-Sung Kim, Dong Chan Lee, Choon Keun Park
Background and Study Aims The technique and instrumentation of percutaneous endoscopic lumbar diskectomy (PELD) have significantly improved. Thus its indications have been gradually expanding. Down-migrated disk, in particular, is regarded inaccessible by rigid instrumentation due to poor visualization and limited accessibility. We introduce a combination of transforaminal and interlaminar PELD for extensive down-migrated disk herniation at the L4-L5 level. Patients and Methods In the first case, a 48-year-old man had left L5 radicular pain...
April 28, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28454185/patella-dislocation-in-children-and-adolescents
#3
Sven Höhne, Kristina Gerlach, Lars Irlenbusch, Mathias Schulz, Christian Kunze, Rainer Finke
Introduction Patellar dislocation is one of the commonest knee injuries in adolescents. Although treatment usually leads to good results, the influence of anatomical and functional factors on therapeutic strategy has been underestimated, especially in cases of recurrence. Patients and Methods The course of treatment has been analysed in 88 patients with 136 patellar dislocations. The importance of anatomical conditions was studied using X-ray and MRI findings. The treatment results were critically evaluated in comparison with current recommendations...
April 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28454166/fabrication-of-multipoint-side-firing-optical-fiber-by-laser-micro-ablation
#4
Hoang Nguyen, Md Masud Parvez Arnob, Aaron T Becker, John C Wolfe, Matthew K Hogan, Philip J Horner, Wei-Chuan Shih
A multipoint, side-firing design enables an optical fiber to output light at multiple desired locations along the fiber body. This provides advantages over traditional end-to-end fibers, especially in applications requiring fiber bundles such as brain stimulation or remote sensing. This Letter demonstrates that continuous wave (CW) laser micro-ablation can controllably create conical-shaped cavities, or side windows, for outputting light. The dimensions of these cavities determine the amount of firing light and their firing angle...
May 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28454128/2-3-%C3%AE-m-tm-sup-3-sup-ylf-laser-passively-q-switched-with-a-cr-sup-2-sup-znse-saturable-absorber
#5
Ferda Canbaz, Ismail Yorulmaz, Alphan Sennaroglu
We report, what is to our knowledge, the first passively Q-switched operation of a 2.3-μm Tm<sup>3+</sup>:YLF laser by using a Cr<sup>2+</sup>:ZnSe saturable absorber. In the experiments, a tunable Ti<sup>3+</sup>:sapphire laser was used to end pump the Tm<sup>3+</sup>:YLF gain medium inside an x cavity. A Cr<sup>2+</sup>:ZnSe saturable absorber was also included in the cavity to initiate passive Q switching. At all pump power levels above lasing threshold, passively Q-switched operation of the Tm<sup>3+</sup>:YLF laser could be obtained at 2309 nm with pulse durations and repetition frequencies in the ranges of 1...
May 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/28454115/impact-of-marital-status-during-diagnosis-on-cancer-caused-specific-survival-in-acute-myeloid-leukemia-patients-a-case-control-and-population-based-study
#6
Zhuojun Zheng, Yuandong Zhu, Xiaodong Li, Wenwei Hu, Jingting Jiang
OBJECTIVE: This study investigated the impact of marital status on cancer-caused specific mortality among acute myeloid leukemia (AML) patients in the United States. METHODS: We used the Surveillance, Epidemiology and End Results program to identify 50,825 patients who had their clinical and follow-up information available and were diagnosed for AML between the years 1988 and 2015. The univariate and multivariable Cox regression models were used to analyze the patient data, and to minimize the group differences due to covariates between groups, a 1:1 propensity score matching was used in subsequent subgroup analysis...
April 9, 2017: Oncotarget
https://www.readbyqxmd.com/read/28454107/timing-of-chemotherapy-induced-neutropenia-the-prognostic-factor-in-advanced-pancreatic-cancer-patients-treated-with-gemcitabine-gemcitabine-based-chemotherapy
#7
Yang Chen, Yan Shi, Huan Yan, Yan Rong Wang, Guang Hai Dai
Chemotherapy-induced neutropenia (CIN) was reported to be a predictor of better survival in several cancers. The objective of our study is to evaluate the relationship between the timing (onset) of CIN and prognosis. Between June 2008 and June 2015, 134 patients with confirmed advanced pancreatic cancer received at least one cycle of gemcitabine / gemcitabine-based chemotherapy as first-line chemotherapy were eligible for assessment. Timing of CIN was categorized into early onset and non-early onset CIN group...
April 9, 2017: Oncotarget
https://www.readbyqxmd.com/read/28454103/subchronic-arsenism-induced-oxidative-stress-and-inflammatory-contribute-to-apoptosis-through-mitochondrial-and-death-receptor-dependent-pathways-in-chicken-immune-organs
#8
Hongjing Zhao, Ying He, Siwen Li, Xiao Sun, Yu Wang, Yizhi Shao, Zhijun Hou, Mingwei Xing
In many organ dysfunctions, arsenic and its compounds are well known to induce apoptosis by the mitochondria and death receptor apoptotic pathways in liver and airway. However, it is less reported that which signaling pathways contribute to excessive apoptosis of chicken immune organs, a major target of toxic metals biotransformation, which suffer from subchronic arsenism. In this study, we investigated whether the mitochondria or death receptor apoptotic pathways activated in the immune organs (spleen, thymus and bursa of Fabricius) of one-day-old male Hy-line chickens exposed to arsenic trioxide (As2O3), which were fed on diets supplemented with 0, 0...
April 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28454085/baseline-clinical-predictors-of-antitumor-response-to-the-parp-inhibitor-olaparib-in-germline-brca1-2-mutated-patients-with-advanced-ovarian-cancer
#9
Saeed Rafii, Charlie Gourley, Rajiv Kumar, Elena Geuna, Joo Ern Ang, Tzyvia Rye, Lee-May Chen, Ronnie Shapira-Frommer, Michael Friedlander, Ursula Matulonis, Jacques De Greve, Amit M Oza, Susana Banerjee, L Rhoda Molife, Martin E Gore, Stan B Kaye, Timothy A Yap
BACKGROUND: The PARP inhibitor olaparib was recently granted Food and Drug Administration (FDA) accelerated approval in patients with advanced BRCA1/2 mutation ovarian cancer. However, antitumor responses are observed in only approximately 40% of patients and the impact of baseline clinical factors on response to treatment remains unclear. Although platinum sensitivity has been suggested as a marker of response to PARP inhibitors, patients with platinum-resistant disease still respond to olaparib...
April 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/28454083/comparison-of-long-term-outcome-between-hemicolectomy-and-partial-colectomy-in-the-elderly-a-large-population-based-study
#10
Xu Guan, Hanqing Hu, Wei Chen, Zheng Jiang, Zheng Liu, Zhixun Zhao, Yinggang Chen, Guiyu Wang, Xishan Wang
Due to large progress has been achieved in surgical techniques, anesthesia and perioperative care, it is accepted that the very elderly colon cancer (CC) patient is not contraindication for surgery. However, it is a controversy that an extended or a less aggressive surgical approach should be performed for this population. Here, we identified 28110 CC patients aged ≥80 from Surveillance, Epidemiology, and End-Results (SEER) database. The surgical approaches included extended hemicolectomy (HC) and partial colectomy (PC)...
April 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/28454061/evaluation-of-a-pilot-innovative-cognitive-behavioral-therapy-based-psychoeducation-group-treatment-for-functional-non-epileptic-attacks
#11
Sarah R Cope, Jared G Smith, Tara King, Niruj Agrawal
A high proportion of patients presenting at epilepsy clinics experience functional non-epileptic attacks (FNEA), and while psychological treatment is generally thought to be the required intervention, evidence regarding psychological treatment of FNEA is limited. A small number of psychoeducation treatments have been evaluated, with promising results. As part of routine care within a neuropsychiatry service, a 3-session cognitive-behavior therapy- (CBT-) informed psychoeducation group was developed. Patients with comorbid epilepsy were included...
April 25, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28453993/sexual-violence-interventions-considerations-for-humanitarian-settings
#12
David Wells
Sexual and gender based violence may result in a range of destructive consequences to the individual, their family and the wider community. Addressing such violence and its immediate aftermath in circumstances of civil turmoil requires a timely, planned and coordinated multidisciplinary response. Such interventions need to be cognisant of, and address a range of challenges which might include economic barriers, religious and cultural divides, a dearth of respect for human rights and limited access or capacity of medical, policing and legal services...
April 14, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28453979/effects-of-replacement-of-beef-fat-with-interesterified-palm-kernel-oil-on-the-quality-characteristics-of-turkish-dry-fermented-sausage
#13
Birol Kılıç, Cem Okan Özer
The objective of this study was to investigate the effects of replacing beef fat with enzymatic interesterified palm kernel oil (IPKO) on the quality characteristics and storage stability of sucuk (Turkish dry-fermented sausage). The partial (25, 50, 75%) and complete (100%) replacement of added beef fat with IPKO were carried out during sucuk processing. According to the study results, replacement of beef fat with IPKO resulted in significant increase in the concentrations of caprylic, capric, lauric and mryistic acid and decrease in the concentrations of stearic, oleic and linoleic acid in sucuk (P<0...
April 21, 2017: Meat Science
https://www.readbyqxmd.com/read/28453938/simulated-force-quench-dynamics-shows-gb1-protein-is-not-a-two-state-folder
#14
Ronen Berkovich, Jagannath Mondal, Inga Paster, Bruce J Berne
Single molecule force spectroscopy is a useful technique for investigating mechanically induced protein unfolding and refolding under reduced forces by monitoring the end-to-end distance of the protein, Ree. The data is often interpreted via a "two-state" model based on the assumption that Ree alone is a good reaction coordinate and the thermodynamic behavior is then ascribed to the free energy as a function of this one reaction coordinate. In this paper, we determined the free energy surface (PMF) of GB1 protein from atomistic simulations in explicit solvent under different applied forces as a function of two collective variables (Ree, and the fraction of native contacts ρ)...
April 28, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28453910/central-nervous-system-disease-in-pediatric-acute-myeloid-leukemia-a-report-from-the-children-s-oncology-group
#15
Donna L Johnston, Todd A Alonzo, Robert B Gerbing, Richard Aplenc, William G Woods, Soheil Meshinchi, Alan S Gamis
BACKGROUND: The prognostic impact of central nervous system (CNS) involvement in children with acute myeloid leukemia (AML) has varied in past trials, and controversy exists over the degree of involvement requiring intensified CNS therapy. Two recent Children's Oncology Group protocols, AAML03P1 and AAML0531, directed additional intrathecal (IT) therapy to patients with CNS2 (≤5 white blood cell [WBC] with blasts) or CNS3 (>5 WBC with blasts or CNS symptoms) disease at diagnosis...
April 28, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28453908/sexual-dysfunction-in-subjects-treated-with-inhibitors-of-5%C3%AE-reductase-for-benign-prostatic-hyperplasia-a-comprehensive-review-and-meta-analysis
#16
REVIEW
G Corona, G Tirabassi, D Santi, E Maseroli, M Gacci, M Dicuio, A Sforza, E Mannucci, M Maggi
Despite their efficacy in the treatment of benign prostatic hyperplasia, the popularity of inhibitors of 5α-reductase (5ARIs) is limited by their association with adverse sexual side effects. The aim of this study was to review and meta-analyze currently available randomized clinical trials evaluating the rate of sexual side effects in men treated with 5ARIs. An extensive Medline Embase and Cochrane search was performed including the following words: 'finasteride', 'dutasteride', 'benign prostatic hyperplasia'...
April 28, 2017: Andrology
https://www.readbyqxmd.com/read/28453901/quasi-static-acoustic-tweezing-thromboelastometry
#17
R G Holt, D Luo, N Gruver, D B Khismatullin
BACKGROUND: Thromboelastography is widely used as a tool to assess the coagulation status of surgical patients. It allows observation of changes in material properties of whole blood, beginning with early stages of clot formation and ending with clot lysis. However, the contact activation of the coagulation cascade at surfaces of thromboelastographic systems leads to inherent variability and unreliability in predicting bleeding or thrombosis risks. OBJECTIVES: To develop acoustic tweezing thromboelastometry as a noncontact method for perioperative assessment of blood coagulation...
April 28, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28453799/early-to-mid-term-results-after-total-cavopulmonary-connection-performed-in-the-second-decade-of-life
#18
Alexandre Metras, Virginie Fouilloux, Mohammed Al-Yamani, Xavier Roques, Loic Macé, Jean-Benoît Thambo, Dominique Metras, Bernard Kreitmann, François Roubertie
OBJECTIVES: Total cavopulmonary connection (TCPC) performed in the second decade of life has rarely been studied. Thus, we investigated (bicentric study) early and late morbidity and mortality following completion of TCPC in these patients. METHODS: From January 1999 to June 2014, 63 patients (14.5 ± 2.9 years) underwent TCPC (extracardiac conduit). Palliation before completion was an isolated bidirectional cavopulmonary shunt (BCPS) in 3 patients or BCPS associated with additional pulmonary blood flow (APBF) that was either antegrade (Group 1) in 38 (63%) or retrograde (Group 2) in 22 (37%)...
May 1, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28453795/closing-the-gap-in-paediatric-ventricular-assist-device-therapy-with-the-berlin-heart-excor%C3%A2-15-ml-pump%C3%A2
#19
Fabrizio De Rita, Massimo Griselli, Eugen Sandica, Oliver Miera, Ann Karimova, Yves d'Udekem, Ranny Goldwasser, Katarzyna Januszewska, Antonio Amodeo, Nadine Jurrmann, Simon Ersel, Ares K Menon
OBJECTIVES: The Berlin Heart EXCOR ® (EXCOR) paediatric ventricular assist device is used worldwide for mechanical support of infants and small children with end-stage heart failure. A clinically important gap between the smallest EXCOR blood pump (10 ml) and the next larger size (25 ml) limited the choice of pump size in patients with a body surface area (BSA) between 0.33 and 0.5 m 2 . We present the first clinical experience from the early product surveillance (EPS) of the new EXCOR 15-ml blood pump...
May 1, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28453785/structural-and-functional-characterization-of-the-pnkp-xrcc4-ligiv-dna-repair-complex
#20
R Daniel Aceytuno, Cortt G Piett, Zahra Havali-Shahriari, Ross A Edwards, Martial Rey, Ruiqiong Ye, Fatima Javed, Shujuan Fang, Rajam Mani, Michael Weinfeld, Michal Hammel, John A Tainer, David C Schriemer, Susan P Lees-Miller, J N Mark Glover
Non-homologous end joining (NHEJ) repairs DNA double strand breaks in non-cycling eukaryotic cells. NHEJ relies on polynucleotide kinase/phosphatase (PNKP), which generates 5΄-phosphate/3΄-hydroxyl DNA termini that are critical for ligation by the NHEJ DNA ligase, LigIV. PNKP and LigIV require the NHEJ scaffolding protein, XRCC4. The PNKP FHA domain binds to the CK2-phosphorylated XRCC4 C-terminal tail, while LigIV uses its tandem BRCT repeats to bind the XRCC4 coiled-coil. Yet, the assembled PNKP-XRCC4-LigIV complex remains uncharacterized...
April 27, 2017: Nucleic Acids Research
keyword
keyword
98197
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"