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https://www.readbyqxmd.com/read/29680329/dual-diagnosis-of-mental-illness-and-substance-use-disorder-and-injury-in-adults-recently-released-from-prison-a-prospective-cohort-study
#1
Jesse T Young, Ed Heffernan, Rohan Borschmann, James R P Ogloff, Matthew J Spittal, Fiona G Kouyoumdjian, David B Preen, Amanda Butler, Lisa Brophy, Julia Crilly, Stuart A Kinner
BACKGROUND: People with mental illness and substance use disorder are over-represented in prisons. Injury-related mortality is elevated in people released from prison, and both mental illness and substance use disorder are risk factors for injury. Effective care coordination during the transition between criminal justice and community service providers improves health outcomes for people released from prison. However, the health outcomes and support needs of people with dual diagnosis (co-occurring mental illness and substance use disorder) released from prison are poorly understood...
April 17, 2018: Lancet. Public Health
https://www.readbyqxmd.com/read/29568152/comparative-piv-and-lda-studies-of-newtonian-and-non-newtonian-flows-in-an-agitated-tank
#2
Anna Story, Zdzisław Jaworski, Mark J Simmons, Emilia Nowak
The paper presents results of an experimental study of the fluid velocity field in a stirred tank equipped with a Prochem Maxflo T (PMT) type impeller which was rotating at a constant frequency of N  = 4.1 or 8.2 s-1 inducing transitional ( Re  = 499 or 1307) or turbulent ( Re  = 2.43 × 104 ) flow of the fluid. The experiments were performed for a Newtonian fluid (water) and a non-Newtonian fluid (0.2 wt% aqueous solution of carboxymethyl cellulose, CMC) exhibiting mild viscoelastic properties. Measurements were carried out using laser light scattering on tracer particles which follow the flow (2-D PIV)...
2018: Chemické Zvesti
https://www.readbyqxmd.com/read/29567197/bone-regeneration-in-osteoporosis-by-delivery-bmp-2-and-prgf-from-tetronic-alginate-composite-thermogel
#3
Elisabet Segredo-Morales, Patricia García-García, Ricardo Reyes, Edgar Pérez-Herrero, Araceli Delgado, Carmen Évora
As the life expectancy of the world population increases, osteoporotic (OP) fracture risk increase. Therefore in the present study a novel injectable thermo-responsive hydrogel loaded with microspheres of 17β-estradiol, microspheres of bone morphogenetic protein-2 (BMP-2) and plasma rich in growth factors (PRGF) was applied locally to regenerate a calvaria critical bone defect in OP female rats. Three systems were characterized: Tetronic® 1307 (T-1307) reinforced with alginate (T-A), T-A with PRGF and T-A-PRGF with microspheres...
March 19, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29513083/multicenter-assessment-of-antibiotic-prophylaxis-spectrum-on-surgical-infections-in-head-and-neck-cancer-microvascular-reconstruction
#4
Michael P Veve, Joshua B Greene, Amy M Williams, Susan L Davis, Nina Lu, Yelizaveta Shnayder, David X Li, Salem I Noureldine, Jeremy D Richmon, Lawrence O Lin, Matthew M Hanasono, Patrik Pipkorn, Ryan S Jackson, Joshua D Hornig, Tyler Light, Mark K Wax, Yin Yiu, James Bekeny, Matthew Old, David Hernandez, Urjeet A Patel, Tamer A Ghanem
Objective To characterize and identify risk factors for 30-day surgical site infections (SSIs) in patients with head and neck cancer who underwent microvascular reconstruction. Study Design Cross-sectional study with nested case-control design. Setting Nine American tertiary care centers. Subjects and Methods Hospitalized patients were included if they underwent head and neck cancer microvascular reconstruction from January 2003 to March 2016. Cases were defined as patients who developed 30-day SSI; controls were patients without SSI at 30 days...
March 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29484852/skeletal-muscle-fiber-type-specific-changes-in-markers-of-capillary-and-mitochondrial-content-after-low-volume-interval-training-in-overweight-women
#5
Rachel Tan, Joshua P Nederveen, Jenna B Gillen, Sophie Joanisse, Gianni Parise, Mark A Tarnopolsky, Martin J Gibala
High-intensity interval training (HIIT) enhances skeletal muscle oxygen delivery and utilization but data are limited regarding fiber-specific adaptations in humans. We examined the effect of 18 sessions of HIIT (10 × 60-sec cycling intervals at ~90% HRmax , interspersed by 60-sec of recovery) over 6 weeks on markers of microvascular density and oxidative capacity in type I and II fibers in healthy but sedentary young women (Age: 26 ± 7 years; BMI: 30 ± 4 kg·m-2 ; VO2peak : 2.16 ± 0.45 L·m-1 )...
March 2018: Physiological Reports
https://www.readbyqxmd.com/read/29453188/web-based-alcohol-smoking-and-substance-involvement-screening-test-results-for-the-general-spanish-population-cross-sectional-study
#6
Juan A Lopez-Rodriguez, Gabriel Rubio Valladolid
BACKGROUND: Information technology in health sciences could be a screening tool of great potential and has been shown to be effective in identifying single-drug users at risk. Although there are many published tests for single-drug screening, there is a gap for concomitant drug use screening in general population. The ASSIST (Alcohol, Smoking and Substance Involvement Screening Test) website was launched on February 2015 in Madrid, Spain, as a tool to identify those at risk. OBJECTIVE: The aim of this study was to describe the use of a tool and to analyze profiles of drug users, their consumption patterns, and associated factors...
February 16, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29435412/mirnaexpression-profile-of-retinal-pigment-epithelial-cells-under-oxidative-stress-conditions
#7
Luigi Donato, Placido Bramanti, Concetta Scimone, Carmela Rinaldi, Rosalia D'Angelo, Antonina Sidoti
Deep analysis of regulative mechanisms of transcription and translation in eukaryotes could improve knowledge of many genetic pathologies such as retinitis pigmentosa (RP). New layers of complexity have recently emerged with the discovery that 'junk' DNA is transcribed and, among these, miRNAs have assumed a preponderant role. We compared changes in the expression of miRNAs obtained from whole transcriptome analyses, between two groups of retinal pigment epithelium (RPE) cells, one untreated and the other exposed to the oxidant agent oxidized low-density lipoprotein (oxLDL), examining four time points (1, 2, 4 and 6 h)...
February 2018: FEBS Open Bio
https://www.readbyqxmd.com/read/29429817/assessing-the-effect-of-adherence-on-patient-reported-outcomes-and-out-of-pocket-costs-among-patients-with-multiple-myeloma
#8
Shaloo Gupta, Safiya Abouzaid, Ryan Liebert, Kejal Parikh, Brian Ung, Aaron S Rosenberg
BACKGROUND: The present study characterized the effect of multiple myeloma (MM) on work productivity, health care resource usage, and out of pocket costs (OOPCs) and examined the association of adherence with quality of life (QoL) and productivity loss. MATERIALS AND METHODS: The present cross-sectional study included 162 patients categorized by their 4-item Morisky Medication Adherence Scale (MMAS-4) score (4 vs. ≤ 3). Online surveys included the Work Productivity and Activity Impairment questionnaire, Functional Assessment of Cancer Therapy-Multiple Myeloma (FACT-MM), and MM-specific questions...
January 31, 2018: Clinical Lymphoma, Myeloma & Leukemia
https://www.readbyqxmd.com/read/29400588/polymorphism-of-the-dna-methyltransferase-1-gene-is-associated-with-the-susceptibility-to-essential-hypertension-in-male
#9
Hui-Ling Chen, Zhan-Ming Li, Jin-Feng Liu, Bing Han, Zhao-Xia Wu, Yu-Qin Mao, Ke-Yu Sun, Li-Shun Wang
Essential hypertension is a leading global public health issue, billions of people suffered from it every year. Recently, multiple evidence suggests that DNA methylation play an important role in regulating blood pressure. Here, we tested the risk for essential hypertension conferred by single nucleotide polymorphisms (SNPs) within DNA methyltransferase 1 (DNMT1). Three loci (rs2228611, rs2228612, and rs16999593) were selected to be analyzed in 3410 cases and 1307 normal controls in southern Chinese aged 60 or above...
February 5, 2018: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/29344381/impact-of-nutritional-indices-on-mortality-in-patients-with-heart-failure
#10
Akiomi Yoshihisa, Yuki Kanno, Shunsuke Watanabe, Tetsuro Yokokawa, Satoshi Abe, Makiko Miyata, Takamasa Sato, Satoshi Suzuki, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Hitoshi Suzuki, Takafumi Ishida, Yasuchika Takeishi
Background: Malnutrition is a common condition that is associated with adverse prognosis in patients with heart failure (HF). The Prognostic Nutritional Index (PNI), Geriatric Nutritional Risk Index (GNRI) and controlling nutritional status (CONUT) have all been used as objective indices for evaluating nutritional status. We aimed to clarify the relationship between these nutritional indices and the parameters of inflammatory markers, cardiac function and exercise capacity, as well as to compare the ability of these indexes for predicting mortality...
2018: Open Heart
https://www.readbyqxmd.com/read/29311539/tolvaptan-for-fluid-management-in-living-donor-liver-transplant-recipients
#11
Shunichi Imai, Masahiro Shinoda, Hideaki Obara, Minoru Kitago, Taizo Hibi, Yuta Abe, Hiroshi Yagi, Kentaro Matsubara, Hisanobu Higashi, Osamu Itano, Yuko Kitagawa
BACKGROUND Tolvaptan, an antagonist of the vasopressin V2 receptor is a novel oral diuretic that promotes water excretion selectively. We have used furosemide as a primary diuretic and added human atrial natriuretic peptide (hANP) if necessary for fluid management postoperatively in living-donor liver transplantation (LDLT) recipients. Recently we introduced tolvaptan and used both tolvaptan and furosemide as primary diuretics. MATERIAL AND METHODS Clinical outcomes were compared between LDLT recipients whose postoperative fluid management was performed before (control group, n=10) and after (tolvaptan group, n=16) introduction of tolvaptan...
January 9, 2018: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/29289869/the-role-of-acculturation-and-binge-drinking-on-smoking-status-among-mexican-americans-comparison-by-border-residence
#12
Frank C Bandiera, Patrice A C Vaeth, Raul Caetano, Eliseo J Pérez-Stable
BACKGROUND: Border Mexican Americans (MA) are exposed to poverty and under-education, all of which are predictors of cigarette smoking. METHODS: This study analyzed two epidemiologic surveys among border and non-border MA. In the border sample, interviews were conducted in urban areas of U.S.-Mexico border counties of California, Arizona, New Mexico, and Texas. The non-border sample consisted of respondents interviewed in Los Angeles, Houston, New York, Philadelphia, and Miami...
February 1, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29273833/prospective-observational-study-on-the-association-between-serum-mannose-binding-lectin-levels-and-severe-outcome-in-critically-ill-patients-with-pandemic-influenza-type-a-h1n1-infection
#13
Elie Zogheib, Remy Nyga, Marjorie Cornu, Boualem Sendid, Julien Monconduit, Vincent Jounieaux, Julien Maizel, Christine Segard, Taïeb Chouaki, Hervé Dupont
BACKGROUND: Mannose-binding lectin (MBL) plays an important role in the innate immune response. In addition to activating the complement, MBL can induce cytokine production and contribute to a deleterious inflammatory response with severe A(H1N1)pdm09 virus infection. Our aim was to determine if serum MBL levels correlate with the risk of mortality in intensive care units (ICU) patients with A(H1N1)pdm09 infection. METHODS: Prospective observational study was performed in ICU patients with acute respiratory distress syndrome due to influenza A(H1N1)pdm09 virus...
February 2018: Lung
https://www.readbyqxmd.com/read/29204138/retraction-pseudopyronine-b-a-potent-antimicrobial-and-anticancer-molecule-isolated-from-a-pseudomonas-mosselii
#14
(no author information available yet)
[This retracts the article on p. 1307 in vol. 7, PMID: 27617005.].
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29195733/changes-in-body-mass-index-and-mid-upper-arm-circumference-in-relation-to-all-cause-mortality-in-older-adults
#15
Laura A Schaap, Tara Quirke, Hanneke A H Wijnhoven, Marjolein Visser
BACKGROUND & AIMS: The assessment of weight loss as an indicator of poor nutritional status in older persons is currently widely applied to establish risk of mortality. Little is known about the relationship between changes in mid-upper arm circumference (MUAC) and mortality in older individuals. The aim of the present study was to examine the association between 3-year change in MUAC and 20-year mortality in community-dwelling older adults and compare this to the association between body mass index (BMI) change and mortality...
November 15, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29188766/larvicidal-pupicidal-and-adulticidal-activities-of-non-polar-solvent-extract-of-cymbopogon-nardus-linn-whole-plant-against-a-mosquito-culex-quinquefasciatus-say
#16
Ikram Ilahi, Ali Muhammad Yousafzai
The present research is aimed to investigate the susceptibility of Cx. quinquefasciatus larvae (2nd and 4th instars), pupae and adults during exposure to various concentrations of C. nardus n-hexane extract. Increase in mortality of larvae and pupae was observed with increase in concentration of the extract solution (R2>0.90). LC50 values of extract for 2nd and 4th instar larvae were 451.8 and 599.6 ppm, respectively. The LC<inf>90</inf> values of extract for 2nd and 4th instar larvae were 2519...
November 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29181643/vibrational-spectroscopy-of-muscular-tissue-intoxicated-by-snake-venom-and-exposed-to-photobiomodulation-therapy
#17
Willians Fernando Vieira, Bruno Kenzo-Kagawa, Maria Helena Mesquita Britto, Helder José Ceragioli, Kumiko Koibuchi Sakane, Vitor Baranauskas, Maria Alice da Cruz-Höfling
The pathogenesis of myonecrosis caused by myotoxins from bothropic venom is associated with local extracellular matrix (ECM) disintegration, hemorrhage, and inflammation. Search for alternative methods associated with serum therapy is mandatory to neutralize the fast development of local damage following snakebites. The experimental use of photobiomodulation therapy (PBMT) in murine models has shown promising results relative to structural and functional recovery from bothropic snakebite-induced myonecrosis...
November 28, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29159407/association-of-salivary-microrna-changes-with-prolonged-concussion-symptoms
#18
Jeremiah J Johnson, Andrea C Loeffert, Jennifer Stokes, Robert P Olympia, Harry Bramley, Steven D Hicks
Importance: Approximately one-third of children who experience a concussion develop prolonged concussion symptoms. To our knowledge, there are currently no objective or easily administered tests for predicting prolonged concussion symptoms. Several studies have identified alterations in epigenetic molecules known as microRNAs (miRNAs) following traumatic brain injury. No studies have examined whether miRNA expression can detect prolonged concussion symptoms. Objective: To evaluate the efficacy of salivary miRNAs for identifying children with concussion who are at risk for prolonged symptoms...
January 1, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/29128576/evaluation-of-tumor-pseudocapsule-status-and-its-prognostic-significance-in-renal-cell-carcinoma
#19
Wei Xi, Jiajun Wang, Li Liu, Ying Xiong, Yang Qu, Zhiyuan Lin, Xiang Chen, Zewei Wang, Jiejie Xu, Jianming Guo
PURPOSE: We determined whether tumor pseudocapsule status, including the extent of invasion by cancer and lack of a pseudocapsule, has prognostic value in renal cell carcinoma. MATERIALS AND METHODS: We retrospectively reviewed the records of 1,577 patients with different stages of renal cell carcinoma who underwent nephrectomy at our institution, of whom 1,307 (82.9%) were eligible for analysis. Presented pseudocapsules were classified as grade 0-completely intact, grade 1-merely involved and grade 2-penetrated...
November 8, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29110802/testosterone-therapy-and-risk-of-acute-myocardial-infarction-in-hypogonadal-men-an-administrative-health-care-claims-study
#20
Hu Li, Lucy Mitchell, Xiang Zhang, Darell Heiselman, Stephen Motsko
BACKGROUND: There are some ongoing debates on the potential link between testosterone therapy (TT) and risk of acute myocardial infarction (MI). AIM: To investigate the association between acute MI and TT use compared with non-use in men having documented hypogonadism (diagnostic International Classification of Diseases, Ninth Revision codes 257.2, 257.8, 257.9, 758.7) in patient claims records. METHODS: This retrospective cohort study used a real-world US-based administrative health care claims database (MarketScan 2004-2013; Truven Health Analytics, Ann Arbor, MI, USA) to compare MI rates between TT-treated men and a cohort of untreated hypogonadal men matched by a calendar time-specific propensity score...
November 2017: Journal of Sexual Medicine
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