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https://www.readbyqxmd.com/read/28815932/polymer-based-hybrid-nanocomposites-a-progress-toward-enhancing-interfacial-interaction-and-tailoring-advanced-applications
#1
REVIEW
Chang-Sik Ha
Organic/inorganic hybrid nanocomposites, in particular polymer based hybrid nanocomposites, constitute emerging advanced materials since they combine unique properties from the inorganic and organic (i. e. polymeric) components. We investigated three different hybrid nanocomposites depending on dimensions of the dispersed phase in the nanometer range,; polymer-layered silicate (PLS) nanocomposites where polymers are mixed with layered silicates, polymer/graphene oxide hybrid nanocomposites, and polymer hybrid nanocomposites with reinforcing polymers with isodimensional phases of inorganic silicas using sol-gel reactions...
August 17, 2017: Chemical Record: An Official Publication of the Chemical Society of Japan ... [et Al.]
https://www.readbyqxmd.com/read/28780975/short-term-and-long-term-results-of-endovascular-and-open-repair-of-abdominal-aortic-aneurysms-in-germany
#2
Christian-Alexander Behrendt, Art Sedrakyan, Henrik Christian Rieß, Franziska Heidemann, Tilo Kölbel, Jörg Petersen, Eike Sebastian Debus
BACKGROUND: Endovascular aortic repair (EVAR) has emerged as a standard of care for abdominal aortic aneurysm (AAA) repair. However, real-world evidence to compare this technology to open aortic repair (OAR) is limited. Major gaps exist related to long-term outcomes of therapies worldwide. METHODS: Health insurance claims data of Germany's third largest insurance provider, DAK-Gesundheit, were used to determine outcomes after interventions for intact AAA (iAAA) and ruptured AAA (rAAA)...
August 3, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28767506/defining-chronic-pain-in-epidemiological-studies-a-systematic-review-and-meta-analysis
#3
Ólöf Anna Steingrímsdóttir, Tormod Landmark, Gary J Macfarlane, Christopher Sivert Nielsen
The objective was to document the operational definitions applied in epidemiological studies of chronic pain and to examine whether pain definitions and other methodological factors are systematically related to prevalence estimates. Medline, EMBASE and PSYCHINFO were searched for original research reports with study samples of at least 1,000 individuals, excluding studies of less than five out of 15 selected body regions and studies solely concerned with specific pain conditions. Meta-analyses and meta-regressions were applied with random effects models; covariates were geography, sampling year, survey method, sampling frame, participation rate, percentage women of all participants, pain duration, and pain location...
July 31, 2017: Pain
https://www.readbyqxmd.com/read/28765854/psa-testing-for-men-at-average-risk-of-prostate-cancer
#4
Bruce K Armstrong, Michael J Barry, Mark Frydenberg, Robert A Gardiner, Ian Haines, Stacy M Carter
Prostate-specific antigen (PSA) testing of men at normal risk of prostate cancer is one of the most contested issues in cancer screening. There is no formal screening program, but testing is common - arguably a practice that ran ahead of the evidence. Public and professional communication about PSA screening has been highly varied and potentially confusing for practitioners and patients alike. There has been much research and policy activity relating to PSA testing in recent years. Landmark randomised controlled trials have been reported; authorities - including the 2013 Prostate Cancer World Congress, the Prostate Cancer Foundation of Australia, Cancer Council Australia, and the National Health and Medical Research Council - have made or endorsed public statements and/or issued clinical practice guidelines; and the US Preventive Services Task Force is revising its recommendations...
July 26, 2017: Public Health Research & Practice
https://www.readbyqxmd.com/read/28764141/morphological-study-of-human-liver-and-its-surgical-importance
#5
Heena J Chaudhari, Minal K Ravat, Vasant H Vaniya, Amul N Bhedi
INTRODUCTION: Liver is the largest abdominal organ located in right hypochondrium, epigastrium and left hypochondrium in upper abdominal cavity. Although the segmental anatomy of the liver has been extensively researched, very few studies have dealt with surface variations of the liver. The major fissures are important landmarks for interpreting the lobar anatomy and locating the liver lesions. AIM: To determine gross anatomical variations of liver and their clinical and surgical implications...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28763420/patients-with-staged-bilateral-total-joint-arthroplasty-in-registries-immortal-time-bias-and-methodological-options
#6
Stéphanie L van der Pas, Rob G H H Nelissen, Marta Fiocco
BACKGROUND: In arthroplasty data, patients with staged bilateral total joint arthroplasty (TJA) pose a problem in statistical analysis. Subgroup analysis, in which patients with unilateral and bilateral TJA are studied separately, is sometimes considered an appropriate solution to the problem; we aim to show that this is not true because of immortal time bias. METHODS: We reviewed patients who underwent staged (at any time) bilateral TJA. The logical fallacy leading to immortal time bias is explained through a simple artificial data example...
August 2, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28756087/a-glimpse-of-membrane-transport-through-structures-advances-in-the-structural-biology-of-the-glut-glucose-transporters
#7
REVIEW
Nieng Yan
The cellular uptake of glucose is an essential physiological process, and movement of glucose across biological membranes requires specialized transporters. The major facilitator superfamily glucose transporters GLUTs, encoded by the SLC2A genes, have been a paradigm for functional, mechanistic, and structural understanding of solute transport in the past century. This review starts with a glimpse into the structural biology of membrane proteins and particularly membrane transport proteins, enumerating the landmark structures in the past 25years...
July 26, 2017: Journal of Molecular Biology
https://www.readbyqxmd.com/read/28752814/a-matter-of-scale-and-dimensions-chromatin-of-chromosome-landmarks-in-the-fungi
#8
Allyson A Erlendson, Steven Friedman, Michael Freitag
Chromatin and chromosomes of fungi are highly diverse and dynamic, even within species. Much of what we know about histone modification enzymes, RNA interference, DNA methylation, and cell cycle control was first addressed in Saccharomyces cerevisiae, Schizosaccharomyces pombe, Aspergillus nidulans, and Neurospora crassa. Here, we examine the three landmark regions that are required for maintenance of stable chromosomes and their faithful inheritance, namely, origins of DNA replication, telomeres and centromeres...
July 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/28749968/analysis-of-age-as-a-factor-in-nasa-astronaut-selection-and-career-landmarks
#9
Gregory T A Kovacs, Mark Shadden
NASA's periodic selection of astronauts is a highly selective process accepting applications from the general population, wherein the mechanics of selection are not made public. This research was an effort to determine if biases (specifically age) exist in the process and, if so, at which points they might manifest. Two sets of analyses were conducted. The first utilized data requested via the Freedom of Information Act (FOIA) on NASA astronaut applicants for the 2009 and 2013 selection years. Using a series of multinomial and logistic regressions, the data were analyzed to uncover whether age of the applicants linearly or nonlinearly affected their likelihood of receiving an invitation, as well as their likelihood of being selected into the astronaut program...
2017: PloS One
https://www.readbyqxmd.com/read/28748331/eligibility-for-phase-3-clinical-trials-of-systemic-therapy-in-real-world-patients-with-metastatic-renal-cell-cancer-managed-in-a-rural-region
#10
Carsten Nieder, Mohsan A Syed, Astrid Dalhaug, Adam Pawinski, Jan Norum
Previous research has identified disparities between urban and rural cancer care, including clinical trial access. Therefore, we addressed three different questions in patients with metastatic renal cell cancer managed according to national guidelines in a rural Norwegian standard practice setting. (1) How many patients would have been eligible for three recent landmark randomized clinical trials? (2) Is survival different between eligible and non-eligible patients receiving first-line systemic therapy? (3) Is survival different between eligible patients and published trial results? We performed a retrospective analysis of 101 consecutive patients (2006-2016)...
September 2017: Medical Oncology
https://www.readbyqxmd.com/read/28740372/pharmacological-treatment-of-osteoporosis-in-the-oldest-old
#11
REVIEW
A Vandenbroucke, F P Luyten, J Flamaing, E Gielen
The incidence of osteoporotic fractures increases with age. Consequently, the global prevalence of osteoporotic fractures will increase with the aging of the population. In old age, osteoporosis is associated with a substantial burden in terms of morbidity and mortality. Nevertheless, osteoporosis in old age continues to be underdiagnosed and undertreated. This may, at least partly, be explained by the fact that evidence of the antifracture efficacy of osteoporosis treatments comes mainly from randomized controlled trials in postmenopausal women with a mean age of 70-75 years...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28736864/brain-tumor-segmentation-using-holistically-nested-neural-networks-in-mri-images
#12
Ying Zhuge, Andra V Krauze, Holly Ning, Jason Y Cheng, Barbara C Arora, Kevin Camphausen, Robert W Miller
PURPOSE: Gliomas are rapidly progressive, neurologically devastating, largely fatal brain tumors. Magnetic Resonance Imaging (MRI) is a widely used technique employed in the diagnosis and management of gliomas in clinical practice. MRI is also the standard imaging modality used to delineate the brain tumor target as part of treatment planning for the administration of radiation therapy. Despite more than 20 years of research and development, computational brain tumor segmentation in MRI images remains a challenging task...
July 24, 2017: Medical Physics
https://www.readbyqxmd.com/read/28725576/cost-consideration-in-utilization-of-multiparametric-magnetic-resonance-imaging-in-prostate-cancer
#13
REVIEW
Ryan Hutchinson, Yair Lotan
The screening, evaluation and management of prostate cancer changed significantly in the last decade. The recommendations regarding prostate cancer screening continue to evolve with new revelations about existing data sets and longer followup of landmark trials. Robotics has gained the vast majority of the marketplace for surgically managed prostate cancer in rapid fashion. The need for intervention in low risk prostate cancer has been closely examined and more men are being expectantly managed than ever before...
June 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28712912/multixplore-visual-exploration-platform-for-multimodal-neuroimaging-data
#14
Saeed M Bakhshmand, Ali R Khan, Sandrine de Ribaupierre, Roy Eagleson
BACKGROUND: Construction of brain functional and structural networks by neuroimaging methods facilitates inter-modal studies. These type of studies often demand exploration tools to carry out functional-structural discoveries and answer questions regarding the anatomical basis of brain networks. NEW METHOD: This paper describes the design and development of a software module for interactive visualization and exploration of dual-modal brain networks. Our objective was to equip the user with a research tool to investigate brain connectivity matrices while visualizing relevant anatomical landmarks within a 3D volumetric view...
July 13, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28707243/research-trends-and-hotspots-related-to-ammonia-oxidation-based-on-bibliometric-analysis
#15
Maosheng Zheng, Hui-Zhen Fu, Yuh-Shan Ho
Ammonia oxidation is the rate-limiting and central step in global biogeochemistry cycle of nitrogen. A bibliometric analysis based on 4314 articles extracted from Science Citation Index Expanded database was carried out to provide insights into publication performances and research trends of ammonia oxidation in the period 1991-2014. These articles were originated from a wide range of 602 journals and 95 Web of Science Categories, among which Applied and Environmental Microbiology and Environmental Sciences took the leading position, respectively...
July 13, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28704414/examining-the-use-of-amazon-s-mechanical-turk-for-edge-extraction-of-the-occlusal-surface-of-fossilized-bovid-teeth
#16
Gregory J Matthews, George K Thiruvathukal, Maxwell P Luetkemeier, Juliet K Brophy
In order to reconstruct environments associated with Plio-Pleistocene hominins in southern Africa, researchers frequently rely upon the animals associated with the hominins, in particular, animals in the Family Bovidae. Bovids in southern Africa are typically identified by their teeth. However, identifying the taxon of a bovid tooth is challenging due to various biasing factors. Furthermore, inaccurate identification of fossil bovids can have significant consequences on the reconstructed paleoenvironment. Recent research on the classification of bovid fossil teeth has relied on using elliptical Fourier analysis to summarize the shape of the outline of the occlusal surface of the tooth and the resulting harmonic amplitudes...
2017: PloS One
https://www.readbyqxmd.com/read/28699568/evaluation-of-the-informatician-perspective-determining-types-of-research-papers-preferred-by-clinicians
#17
Boshu Ru, Xiaoyan Wang, Lixia Yao
BACKGROUND: To deliver evidence-based medicine, clinicians often reference resources that are useful to their respective medical practices. Owing to their busy schedules, however, clinicians typically find it challenging to locate these relevant resources out of the rapidly growing number of journals and articles currently being published. The literature-recommender system may provide a possible solution to this issue if the individual needs of clinicians can be identified and applied...
July 5, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28699246/a-potential-pitfall-in-studies-of-biological-shape-does-size-matter
#18
David Outomuro, Frank Johansson
The number of published studies using geometric morphometrics (GM) for analysing biological shape has increased steadily since the beginning of the 1990's, covering multiple research areas such as ecology, evolution, development, taxonomy and palaeontology. Unfortunately, we have observed that many published studies using GM do not evaluate the potential allometric effects of size on shape, which normally require consideration or assessment. This might lead to misinterpretations and flawed conclusions in certain cases, especially when size effects explain a large part of the shape variation...
July 12, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28686631/a-new-approach-for-the-analysis-of-facial-growth-and-age-estimation-iris-ratio
#19
Carlos Eduardo Palhares Machado, Marta Regina Pinheiro Flores, Laíse Nascimento Correia Lima, Rachel Lima Ribeiro Tinoco, Ademir Franco, Ana Cristina Barreto Bezerra, Martin Paul Evison, Marco Aurélio Guimarães
The study of facial growth is explored in many fields of science, including anatomy, genetics, and forensics. In the field of forensics, it acts as a valuable tool for combating child pornography. The present research proposes a new method, based on relative measurements and fixed references of the human face-specifically considering measurements of the diameter of the iris (iris ratio)-for the analysis of facial growth in association with age in children and sub-adults. The experimental sample consisted of digital photographs of 1000 Brazilian subjects, aged between 6 and 22 years, distributed equally by sex and divided into five specific age groups (6, 10, 14, 18, and 22 year olds ± one month)...
2017: PloS One
https://www.readbyqxmd.com/read/28685390/cancer-care-coordination-a-systematic-review-and-meta-analysis-of-over-30%C3%A2-years-of-empirical-studies
#20
Sherri Sheinfeld Gorin, David Haggstrom, Paul K J Han, Kathleen M Fairfield, Paul Krebs, Steven B Clauser
BACKGROUND: According to a landmark study by the Institute of Medicine, patients with cancer often receive poorly coordinated care in multiple settings from many providers. Lack of coordination is associated with poor symptom control, medical errors, and higher costs. PURPOSE: The aims of this systematic review and meta-analysis were to (1) synthesize the findings of studies addressing cancer care coordination, (2) describe study outcomes across the cancer continuum, and (3) obtain a quantitative estimate of the effect of interventions in cancer care coordination on service system processes and patient health outcomes...
July 6, 2017: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
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