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https://www.readbyqxmd.com/read/28335555/activity-recognition-and-semantic-description-for-indoor-mobile-localization
#1
Sheng Guo, Hanjiang Xiong, Xianwei Zheng, Yan Zhou
As a result of the rapid development of smartphone-based indoor localization technology, location-based services in indoor spaces have become a topic of interest. However, to date, the rich data resulting from indoor localization and navigation applications have not been fully exploited, which is significant for trajectory correction and advanced indoor map information extraction. In this paper, an integrated location acquisition method utilizing activity recognition and semantic information extraction is proposed for indoor mobile localization...
March 21, 2017: Sensors
https://www.readbyqxmd.com/read/28328064/a-bibliometric-analysis-of-pediatric-liver-transplantation-publications
#2
Dermot T McDowell, Alexandre Darani, Albert Shun, Gordon Thomas, Andrew J A Holland
Citation counts can identify landmark papers. The aim of this study was to identify and characterize the top-cited articles in the pediatric liver transplantation literature. A search strategy for the Scopus(®) database was designed for pediatric liver transplantation publications from 1945 to 2014. The 50 top-cited articles were analyzed. Author co-citation analysis was performed using VOSviewer techniques. There were 2896 articles published between 1969 and 2015. The mean citation count of the top 50 cited articles was 166 (range 95-635)...
March 22, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28319004/updated-risk-factors-should-be-used-to-predict-development-of-diabetes
#3
Mary Angelyn Bethel, Kristen A Hyland, Antonio R Chacra, Prakash Deedwania, Gregory R Fulcher, Rury R Holman, Trond Jenssen, Naomi S Levitt, John J V McMurray, Eleni Boutati, Laine Thomas, Jie-Lena Sun, Steven M Haffner
AIMS: Predicting incident diabetes could inform treatment strategies for diabetes prevention, but the incremental benefit of recalculating risk using updated risk factors is unknown. We used baseline and 1-year data from the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial to compare diabetes risk prediction using historical or updated clinical information. METHODS: Among non-diabetic participants reaching 1year of follow-up in NAVIGATOR, we compared the performance of the published baseline diabetes risk model with a "landmark" model incorporating risk factors updated at the 1-year time point...
March 2, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28301271/emerging-trends-and-new-developments-in-monoclonal-antibodies-a-scientometric-analysis-1980-2016
#4
Yunfeng Lai, Ruibing Wang, Xin Chen, Daisheng Tang, Yuanjia Hu, Jing Cai, Qingwen Zhang, Hao Hu
This article aims to explore the intellectual landscape of the study of monoclonal antibody (mAb), mainly to identify thematic trends, landmark articles and emerging trends involving mAb. This work is based on 4 sets of bibliographic records retrieved from the Web of Science. The final data set, consisting of 7,385 bibliographic records, was combined from the 4 individual data sets. This study explores the document co-citation clusters of 7,385 bibliographic records to identify the origin of mAb and the hot research specialty of this domain by applying CiteSpace software...
February 21, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28282117/metal-selenides-as-efficient-counter-electrodes-for-dye-sensitized-solar-cells
#5
Zhitong Jin, Meirong Zhang, Min Wang, Chuanqi Feng, Zhong-Sheng Wang
Solar energy is the most abundant renewable energy available to the earth and can meet the energy needs of humankind, but efficient conversion of solar energy to electricity is an urgent issue of scientific research. As the third-generation photovoltaic technology, dye-sensitized solar cells (DSSCs) have gained great attention since the landmark efficiency of ∼7% reported by O'Regan and Grätzel. The most attractive features of DSSCs include low cost, simple manufacturing processes, medium-purity materials, and theoretically high power conversion efficiencies...
March 10, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28277835/selective-targeting-of-epigenetic-reader-domains
#6
Holger Greschik, Roland Schüle, Thomas Günther
Epigenetic regulators including writers, erasers, and readers of chromatin marks have been implicated in numerous diseases and are therefore subject of intense academic and pharmaceutical research. While several small-molecule inhibitors targeting writers or erasers are approved drugs or which are being evaluated in clinical trials, the targeting of epigenetic readers has lagged. Proof-of-principle that epigenetic readers are also relevant drug targets was provided by landmark discoveries of selective inhibitors targeting the BET family of acetyl-lysine readers...
March 6, 2017: Expert Opinion on Drug Discovery
https://www.readbyqxmd.com/read/28270526/molecular-population-genetics
#7
Sònia Casillas, Antonio Barbadilla
Molecular population genetics aims to explain genetic variation and molecular evolution from population genetics principles. The field was born 50 years ago with the first measures of genetic variation in allozyme loci, continued with the nucleotide sequencing era, and is currently in the era of population genomics. During this period, molecular population genetics has been revolutionized by progress in data acquisition and theoretical developments. The conceptual elegance of the neutral theory of molecular evolution or the footprint carved by natural selection on the patterns of genetic variation are two examples of the vast number of inspiring findings of population genetics research...
March 2017: Genetics
https://www.readbyqxmd.com/read/28258642/benchmarking-recent-national-practice-in-rectal-cancer-treatment-with-landmark-randomised-controlled-trials
#8
Wernard Aat Antoine Borstlap, Pieter Tanis
AIM: A Snapshot study design eliminates changes in treatment and outcome over time. This population based Snapshot study aimed to determine current practice and outcome of rectal cancer treatment with published landmark randomised controlled trials (RCTs) as a benchmark. METHODS: In this collaborative research project, the dataset of the Dutch Surgical Colorectal Audit was extended with additional treatment and long-term outcome data. All registered patients who underwent resection for rectal cancer in 2011 were eligible...
March 4, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28250713/identification-and-visualization-of-the-intellectual-structure-and-the-main-research-lines-in-nanoscience-and-nanotechnology-at-the-worldwide-level
#9
Teresa Muñoz-Écija, Benjamín Vargas-Quesada, Zaida Chinchilla-Rodríguez
The aim of this paper is to make manifest the intellectual and cognitive structure of nanoscience and nanotechnology (NST) by means of visualization techniques. To this end, we used data from the Web of Science (WoS), delimiting the data to the category NST during the period of 2000-2013, retrieving a total of 198,275 documents. Through direct author citation of these works, we identified their origins and the seminal papers, and through word co-occurrence extracted from the titles and abstracts, the main lines of research were identified...
2017: Journal of Nanoparticle Research: An Interdisciplinary Forum for Nanoscale Science and Technology
https://www.readbyqxmd.com/read/28241890/p53-switches-off-pluripotency-on-differentiation
#10
REVIEW
Tongxiang Lin, Yi Lin
The role of p53 as "a guardian of the genome" has been well established in somatic cells. However, its role in pluripotent stem cells remains much more elusive. Here, we discuss research progress in understanding the role of p53 in pluripotent stem cells and in pluripotent stem cell-like cancer stem cells. The p53 protein, which plays a key role in embryonic stem cells, was first discovered in 2005. Landmark studies of p53-related reprogramming elucidated this protein's importance in induced pluripotent stem cells in 2009...
February 28, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28236129/new-supplemental-landmark-for-the-greater-palatine-foramen-as-found-deep-to-soft-tissue-application-for-the-greater-palatine-nerve-block
#11
Joe Iwanaga, Vlad Voin, Allen Ali Nasseh, Junta Kido, Teppei Tsukiyama, Yasuhiko Kamura, Tsuyoshi Tanaka, Christian Fisahn, Fernando Alonso, Rod J Oskouian, R Shane Tubbs
PURPOSE: Many researches have investigated the morphology of the greater palatine foramina using dry skulls and cone-beam computed tomography. In most studies, some structures in the hard tissue have been measured and statistically analyzed. However, none of the studies has analyzed this foramen in regard to its location with overlying soft tissues, which is so clinically relevant. Therefore, this study was performed to provide the knowledge about relationship between the greater palatine foramen and foveola palatina for a better understanding of dental procedures such as greater palatine nerve block...
February 24, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28220268/anterolateral-ligament-expert-group-consensus-paper-on-the-management-of-internal-rotation-and-instability-of-the-anterior-cruciate-ligament-deficient-knee
#12
REVIEW
Bertrand Sonnery-Cottet, Matthew Daggett, Jean-Marie Fayard, Andrea Ferretti, Camilo Partezani Helito, Martin Lind, Edoardo Monaco, Vitor Barion Castro de Pádua, Mathieu Thaunat, Adrian Wilson, Stefano Zaffagnini, Jacco Zijl, Steven Claes
Purpose of this paper is to provide an overview of the latest research on the anterolateral ligament (ALL) and present the consensus of the ALL Expert Group on the anatomy, radiographic landmarks, biomechanics, clinical and radiographic diagnosis, lesion classification, surgical technique and clinical outcomes. A consensus on controversial subjects surrounding the ALL and anterolateral knee instability has been established based on the opinion of experts, the latest publications on the subject and an exchange of experiences during the ALL Experts Meeting (November 2015, Lyon, France)...
February 20, 2017: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/28217505/noncommunicable-disease-in-rural-india-are-we-seriously-underestimating-the-risk-the-nallampatti-noncommunicable-disease-study
#13
Krishnan Swaminathan, Ganesh Veerasekar, Sujatha Kuppusamy, Mohanraj Sundaresan, Ganesan Velmurugan, Nalla G Palaniswami
AIM: To assess the prevalence of noncommunicable diseases in a true rural farming population in South India and compare the data with the landmark contemporary Indian Council of Medical Research-India Diabetes (ICMR-INDIAB) study. METHODS: Local Ethics Committee approval and informed consent was obtained from all participants. Inclusion criteria were participants, aged ≥20 and ≤85 years, from Nallampatti, a classical farming village from Tamil Nadu state, India...
January 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28217294/molecular-hydrogen-a-therapeutic-antioxidant-and-beyond
#14
REVIEW
Lei Huang
Molecular hydrogen (H2) medicine research has flourished since a landmark publication in Nature Medicine that revealed the antioxidant and cytoprotective effects of hydrogen gas in a focal stroke model. Emerging evidence has consistently demonstrated that molecular hydrogen is a promising therapeutic option for a variety of diseases and the underlying comprehensive mechanisms is beyond pure hydroxyl radicals scavenging. The non-toxicity at high concentrations and rapid cellular diffusion features of molecular hydrogen ensure the feasibility and readiness of its clinical translation to human patients...
October 2016: Medical Gas Research
https://www.readbyqxmd.com/read/28208764/spatial-impairment-and-memory-in-genetic-disorders-insights-from-mouse-models
#15
Sang Ah Lee, Valter Tucci, Giorgio Vallortigara
Research across the cognitive and brain sciences has begun to elucidate some of the processes that guide navigation and spatial memory. Boundary geometry and featural landmarks are two distinct classes of environmental cues that have dissociable neural correlates in spatial representation and follow different patterns of learning. Consequently, spatial navigation depends both on the type of cue available and on the type of learning provided. We investigated this interaction between spatial representation and memory by administering two different tasks (working memory, reference memory) using two different environmental cues (rectangular geometry, striped landmark) in mouse models of human genetic disorders: Prader-Willi syndrome (PWScr(m+/p-) mice, n = 12) and Beta-catenin mutation (Thr653Lys-substituted mice, n = 12)...
February 9, 2017: Brain Sciences
https://www.readbyqxmd.com/read/28196766/projecting-the-self-outside-the-body-body-representations-underlying-proprioceptive-imagery
#16
Nataşa Ganea, Matthew R Longo
Recent research has shown that proprioception relies on distorted representations of body size and shape. By asking participants to localise multiple landmarks on their occluded hand, perceptual maps of hand size and shape can be constructed and compared to actual hand structure. These maps are different from the actual size and shape of the occluded hand, revealing underestimation of finger length and overestimation of hand width. Here we tested whether the same distorted body model underlies proprioceptive imagery (i...
February 11, 2017: Cognition
https://www.readbyqxmd.com/read/28192864/a-reassessment-of-cervical-surface-anatomy-via-ct-scan-in-an-adult-population
#17
Xin-Hua Shen, Hua-Dan Xue, Yu Chen, Man Wang, S Ali Mirjalili, Zhu-Hua Zhang, Chao Ma
Surface landmarks in the neck are important for orientations of cervical glands, arteries, veins, nerves, and vertebrae. Recent research suggests some orientations are not correct. What are the cervical landmark orientations in the Chinese population? In this study, two essential cervical anatomy planes, the thyroid cartilage and C7 planes, were assessed in living adult Chinese subjects using computed tomography (CT), and the hyoid, carotid bifurcation, cricoid cartilage, thyroid arteries, and vertebral artery were simultaneously positioned...
April 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28183212/3d-biometrics-for-hindfoot-alignment-using-weightbearing-ct
#18
François Lintz, Matthew Welck, Alessio Bernasconi, James Thornton BSc, Nicholas P Cullen, Dishan Singh, Andy Goldberg
BACKGROUND: Hindfoot alignment on 2D radiographs can present anatomical and operator-related bias. In this study, software designed for weightbearing computed tomography (WBCT) was used to calculate a new 3D biometric tool: the Foot and Ankle Offset (FAO). We described the distribution of FAO in a series of data sets from clinically normal, varus, and valgus cases, hypothesizing that FAO values would be significantly different in the 3 groups. METHODS: In this retrospective cohort study, 135 data sets (57 normal, 38 varus, 40 valgus) from WBCT (PedCAT; CurveBeam LLC, Warrington, PA) were obtained from a specialized foot and ankle unit...
February 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28174317/dual-antiplatelet-therapy-and-clinical-outcomes-after-coronary-drug-eluting-stent-implantation-in-patients-on-hemodialysis
#19
Yung-Tai Chen, Hung-Ta Chen, Chien-Yi Hsu, Pei-Wen Chao, Shu-Chen Kuo, Shuo-Ming Ou, Chia-Jen Shih
BACKGROUND AND OBJECTIVES: We aimed to investigate the benefits and risks of dual antiplatelet therapy (DAPT) after coronary drug-eluting stent (DES) implantation in patients undergoing hemodialysis. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: A nested case-control analysis of patients on hemodialysis after receipt of DES and DAPT treatment was conducted using data from Taiwan's National Health Insurance Research Database for the period 2007-2011. Cases of myocardial infarction or death within 1 year after DES implantation were matched one-to-one with control patients...
February 7, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28168691/sexual-dimorphism-of-the-first-rib-a-comparative-approach-using-metric-and-geometric-morphometric-analyses
#20
Jeffrey James Lynch, Peter Cross, Vivienne Heaton
This research investigated the sexual dimorphism of the first human rib using geometric morphometric and metric approaches on a sample of 285 specimens containing European Americans and African Americans from the Hamann-Todd collection. Metric measurements were investigated for sexual dimorphism and ancestral differences using univariate statistics. Four type II landmarks and 40 sliding semi-landmarks were placed outlining the dorsal and ventral curvatures of the ribs. Landmark data were processed using Generalized Procrustes Analyses with Procrustes distance sliding, and the subsequent coordinates were investigated for sexual dimorphism and ancestral differences using Procrustes ANOVAs...
February 7, 2017: Journal of Forensic Sciences
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