Hannah Cohen, Maria J Cuadrado, Doruk Erkan, Ali Duarte-Garcia, David A Isenberg, Jason S Knight, Thomas L Ortel, Anisur Rahman, Jane E Salmon, Maria G Tektonidou, David J Williams, Rohan Willis, Scott C Woller, Danieli Andrade
Antiphospholipid syndrome (APS), an acquired autoimmune thrombophilia, is characterised by thrombosis and/or pregnancy morbidity in association with persistent antiphospholipid antibodies. The 16th International Congress on Antiphospholipid Antibodies Task Force on APS Treatment Trends reviewed the current status with regard to existing and novel treatment trends for APS, which is the focus of this Task Force report. The report addresses current treatments and developments since the last report, on the use of direct oral anticoagulants in patients with APS, antiplatelet agents, adjunctive therapies (hydroxychloroquine, statins and vitamin D), targeted treatment including rituximab, belimumab, and anti-TNF agents, complement inhibition and drugs based on peptides of beta-2-glycoprotein I...
October 2020: Lupus