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https://www.readbyqxmd.com/read/28938326/progress-on-botulinum-toxin-type-a-induced-pain-relief-in-the-field-of-plastics
#1
Xiaona Lu, Guocheng Chen, Pengjie Ren, Yan Yang, Fei Fan
OBJECTIVE: To retrospectively evaluate the effectiveness of Botulinum Toxin Type A (BTX-A) injections relieve pain in the field of plastic surgery and postoperative rehabilitation, and discuss the analgesic mechanism of BTX- A in plastics and related research progress. METHODS: From appearance to September 1, 2016, PUBMED, EMBASE, and Web of Science were searched, using the key words related to "Botulinum Toxin Type A" and "Pain." Furtherly, nonplastic surgery-related literature was excluded by manual screening...
September 21, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28927643/a-combined-kinematic-and-kinetic-analysis-at-the-residuum-socket-interface-of-a-knee-disarticulation-amputee
#2
Jinghua Tang, Michael McGrath, Nick Hale, Liudi Jiang, Dan Bader, Piotr Laszczak, David Moser, Saeed Zahedi
The bespoke interface between a lower limb residuum and a prosthetic socket is critical for an amputee's comfort and overall rehabilitation outcomes. Analysis of interface kinematics and kinetics is important to gain full understanding of the interface biomechanics, which could aid clinical socket fit, rehabilitation and amputee care. This pilot study aims to investigate the dynamic correlation between kinematic movement and kinetic stresses at the interface during walking tests on different terrains. One male, knee disarticulation amputee participated in the study...
September 15, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28926380/osseointegrated-transtibial-implants-in-patients-with-peripheral-vascular-disease-a-multicenter-case-series-of-5-patients-with-1-year-follow-up
#3
MULTICENTER STUDY
Robin Atallah, Jiao Jiao Li, William Lu, Ruud Leijendekkers, Jan Paul Frölke, Munjed Al Muderis
BACKGROUND: Osseointegration is an alternative treatment for amputees who are unable to wear or have difficulty wearing a socket prosthesis. Although the majority of limb amputations are due to vascular disease, such amputations have been perceived as a contraindication to osseointegration surgery. We report the outcomes of osseointegrated reconstruction in a series of 5 patients with limb amputation due to peripheral vascular disease. METHODS: Five patients with transtibial amputation and a history of peripheral vascular disease who received an osseointegration implant from 2014 to 2015 were followed for 12 months...
September 20, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28921418/coping-with-phantom-limb-pain
#4
Damien P Kuffler
Phantom limb pain is a chronic neuropathic pain that develops in 45-85% of patients who undergo major amputations of the upper and lower extremities and appears predominantly during two time frames following an amputation: the first month and later about 1 year. Although in most patients the frequency and intensity of pain diminish over time, severe pain persists in about 5-10%. It has been proposed that factors in both the peripheral and central nervous systems play major roles in triggering the development and maintenance of pain associated with extremity amputations...
September 18, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28886154/validity-and-reliability-of-a-novel-3d-scanner-for-assessment-of-the-shape-and-volume-of-amputees-residual-limb-models
#5
Elena Seminati, David Canepa Talamas, Matthew Young, Martin Twiste, Vimal Dhokia, James L J Bilzon
BACKGROUND: Objective assessment methods to monitor residual limb volume following lower-limb amputation are required to enhance practitioner-led prosthetic fitting. Computer aided systems, including 3D scanners, present numerous advantages and the recent Artec Eva scanner, based on laser free technology, could potentially be an effective solution for monitoring residual limb volumes. PURPOSE: The aim of this study was to assess the validity and reliability of the Artec Eva scanner (practical measurement) against a high precision laser 3D scanner (criterion measurement) for the determination of residual limb model shape and volume...
2017: PloS One
https://www.readbyqxmd.com/read/28885716/micrornas-are-potential-objective-and-early-biomarkers-for-acute-rejection-of-transplanted-limbs-in-a-rat-model
#6
Hiroki Oda, Ryosuke Ikeguchi, Tomoki Aoyama, Souichi Ohta, Takashi Noguchi, Yukitoshi Kaizawa, Hirofumi Yurie, Hisataka Takeuchi, Koji Yamamoto, Shuichi Matsuda
BACKGROUND: Limb transplantation is considered to be a treatment option for amputees. Visual skin inspection and histological assessment are used to assess rejection, but these techniques are largely subjective. Using a rat model, we examined the potential of several microRNAs (miRNAs) to be used as objective and minimally invasive biomarkers of acute rejection of transplanted limbs. METHODS: Three Brown Norway rats and 15 Lewis rats were assigned to 2 groups. In the allograft group, 3 Brown Norway rats were used as the donors and 6 Lewis rats as the recipients...
September 8, 2017: Microsurgery
https://www.readbyqxmd.com/read/28885156/the-vspa-foot-a-quasi-passive-ankle-foot-prosthesis-with-continuously-variable-stiffness
#7
Max K Shepherd, Elliott J Rouse
Most commercially available prosthetic feet do not exhibit a biomimetic torque-angle relationship, and are unable to modulate their mechanics to assist with other mobility tasks, such as stairs and ramps. In this work, we present a quasi-passive ankle-foot prosthesis with a customizable torque-angle curve and an ability to quickly modulate ankle stiffness between tasks. The customizable torque-angle curve is obtained with a cam-based transmission and a fiberglass leaf spring. To achieve variable stiffness, the leaf spring's support conditions can be actively modulated by a small motor, shifting the torque-angle curve to be more or less stiff...
September 7, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28883640/a-somatotopic-bidirectional-hand-prosthesis-with-transcutaneous-electrical-nerve-stimulation-based-sensory-feedback
#8
Edoardo D'Anna, Francesco M Petrini, Fiorenzo Artoni, Igor Popovic, Igor Simanić, Stanisa Raspopovic, Silvestro Micera
According to amputees, sensory feedback is amongst the most important features lacking from commercial prostheses. Although restoration of touch by means of implantable neural interfaces has been achieved, these approaches require surgical interventions, and their long-term usability still needs to be fully investigated. Here, we developed a non-invasive alternative which maintains some of the advantages of invasive approaches, such as a somatotopic sensory restitution scheme. We used transcutaneous electrical nerve stimulation (TENS) to induce referred sensations to the phantom hand of amputees...
September 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28869812/the-effects-of-prosthetic-foot-stiffness-on-transtibial-amputee-walking-mechanics-and-balance-control-during-turning
#9
Courtney E Shell, Ava D Segal, Glenn K Klute, Richard R Neptune
BACKGROUND: Little evidence exists regarding how prosthesis design characteristics affect performance in tasks that challenge mediolateral balance such as turning. This study assesses the influence of prosthetic foot stiffness on amputee walking mechanics and balance control during a continuous turning task. METHODS: Three-dimensional kinematic and kinetic data were collected from eight unilateral transtibial amputees as they walked overground at self-selected speed clockwise and counterclockwise around a 1-meter circle and along a straight line...
August 15, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28869537/an-adaptive-classification-strategy-for-reliable-locomotion-mode-recognition
#10
Ming Liu, Fan Zhang, He Helen Huang
Algorithms for locomotion mode recognition (LMR) based on surface electromyography and mechanical sensors have recently been developed and could be used for the neural control of powered prosthetic legs. However, the variations in input signals, caused by physical changes at the sensor interface and human physiological changes, may threaten the reliability of these algorithms. This study aimed to investigate the effectiveness of applying adaptive pattern classifiers for LMR. Three adaptive classifiers, i.e...
September 4, 2017: Sensors
https://www.readbyqxmd.com/read/28867909/survival-rate-of-limb-replantation-in-different-age-groups
#11
Masahiro Tatebe, Shiro Urata, Kenji Tanaka, Toshikazu Kurahashi, Shinsuke Takeda, Hitoshi Hirata
Revascularization of damaged limbs/digits is technically feasible, but indications for surgical replantation remain controversial. The authors analyzed the survival rate of upper limb amputations and the associated factors in different age groups. They grouped 371 limb/digit amputees (average age, 44 years; range, 2-85 years) treated in their hospital during the past 10 years into three groups based on age (young, ≤ 15 years, n  = 12; adult, 16-64 years, n  = 302; elderly, ≥ 65 years, n  = 57) and analyzed their injury type (extent of injury and stump status), operation method, presence of medical complications (Charlson comorbidity index), and survival rate...
August 2017: Journal of Hand and Microsurgery
https://www.readbyqxmd.com/read/28860841/a-review-of-the-management-of-phantom-limb-pain-challenges-and-solutions
#12
REVIEW
Cliff Richardson, Jai Kulkarni
BACKGROUND: Phantom limb pain (PLP) occurs in 50% and 80% of amputees. Although it is often classified as a neuropathic pain, few of the large-scale trials of treatments for neuropathic pain included sufficient numbers of PLP sufferers to have confidence that they are effective in this condition. Many therapies have been administered to amputees with PLP over the years; however, as of yet, there appears to be no first-line treatment. OBJECTIVES: To comprehensively review the literature on treatment modalities for PLP and to identify the challenges currently faced by clinicians dealing with this pain...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28858807/bio-inspired-adaptive-control-for-active-knee-exoprosthetics
#13
Anna Pagel, Raffaele Ranzani, Robert Riener, Heike Vallery
On the quest to bring function of prosthetic legs closer to their biological counterparts, intuitive interplay of their control with the user's impedance modulation is key. We present two control features to enable more physiological and more user-adaptive control of prosthetic legs: a neuromusculoskeletal impedance model (NeurImp) including a reflexive component, and a human model reference adaptive controller (HuMRAC), which can be combined with the former. In stance-phase simulations, the NeurImp allowed to control a prosthetic leg with physiological knee joint angle and moment...
August 25, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28858422/development-and-psychometric-properties-of-the-basic-amputee-mobility-score-for-use-in-patients-with-a-major-lower-extremity-amputation
#14
Morten Tange Kristensen, Anni Østergaard Nielsen, Ulla Madsen Topp, Jakob Holmehave-Brandt, Charlotte Falkenberg Petterson, Peter Gebuhr
AIM: To develop and examine the psychometric properties, including responsiveness and interrater reliability, of a new outcome measure for the evaluation of basic mobility activities after a major lower extremity amputation - The Basic Amputee Mobility Score (BAMS). METHODS: The four following essential activities were chosen through consensus meetings with experienced amputee physiotherapists: (i) supine in bed to sitting on the edge of the bed; (ii) bed to wheelchair transfer; (iii) indoor wheelchair mobility; and (iv) get up from a wheelchair to standing on the non-amputated leg...
August 31, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28854522/an-investigation-on-effects-of-amputee-s-physiological-parameters-on-maximum-pressure-developed-at-the-prosthetic-socket-interface-using-artificial-neural-network
#15
Chitresh Nayak, Amit Singh, Himanshu Chaudhary, Deepak Rajendra Unune
Technological advances in prosthetics have attracted the curiosity of researchers in monitoring design and developments of the sockets to sustain maximum pressure without any soft tissue damage, skin breakdown, and painful sores. Numerous studies have been reported in the area of pressure measurement at the limb/socket interface, though, the relation between amputee's physiological parameters and the pressure developed at the limb/socket interface is still not studied. Therefore, the purpose of this work is to investigate the effects of patient-specific physiological parameters viz...
August 1, 2017: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/28853121/characteristics-of-us-combat-veterans-2001-2011-who-remain-on-active-duty-after-upper-extremity-amputations
#16
Sara H Kift, Taylor J Bates, Nathan A Franklin, Anthony E Johnson
OBJECTIVES: Return to duty following traumatic amputations has been extensively studied in those with lower extremity amputation. As upper extremity amputations occur less frequently, the issue of return to duty for those with upper extremity amputations has received relatively little research. The purpose of this study was to determine the rate at which service members remain on active duty at least one year after having sustained traumatic upper extremity amputations during Operation Iraqi Freedom, Operation Enduring Freedom, and other overseas contingency operations of the Global War on Terrorism...
July 2017: U.S. Army Medical Department Journal
https://www.readbyqxmd.com/read/28853120/martial-arts-based-high-intensity-interval-training-in-the-rehabilitation-of-combat-amputees
#17
Gavin L Mills, David J Tennent, Joseph F Aldrete, Anthony E Johnson
No abstract text is available yet for this article.
July 2017: U.S. Army Medical Department Journal
https://www.readbyqxmd.com/read/28846565/swimming-training-reduces-neuroma-pain-by-regulating-neurotrophins
#18
Tian Jinge, Zhang Xin, Yu Tingting, Xu Yongming, Pu Shaofeng, Lv Yingying, Du Dongping
INTRODUCTION: Neuroma formation after peripheral nerve transection leads to severe neuropathic pain in amputees. Previous studies suggested physical exercise could bring beneficial effect on alleviating neuropathic pain. Yet the effect of exercise on neuroma pain still remained unclear. In addition, long-term exercise can affect the expression of neurotrophins (NTs), such as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), which play key roles in nociceptor sensitization and nerve sprouting following nerve injury...
August 25, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28843655/phantom-limbs-neuroprosthetics-and-the-developmental-origins-of-embodiment
#19
REVIEW
Mark S Blumberg, James C Dooley
Amputees who wish to rid themselves of a phantom limb must weaken the neural representation of the absent limb. Conversely, amputees who wish to replace a lost limb must assimilate a neuroprosthetic with the existing neural representation. Whether we wish to remove a phantom limb or assimilate a synthetic one, we will benefit from knowing more about the developmental process that enables embodiment. A potentially critical contributor to that process is the spontaneous activity - in the form of limb twitches - that occurs exclusively and abundantly during active (REM) sleep, a particularly prominent state in early development...
August 23, 2017: Trends in Neurosciences
https://www.readbyqxmd.com/read/28842073/disarticulation-of-the-knee-analysis-of-an-extended-database-on-survival-wound-healing-and-ambulation
#20
Rachelle Nijmeijer, Henricus G J M Voesten, Joannes H B Geertzen, Pieter U Dijkstra
OBJECTIVE: This study analyzed survival of the amputee patients, wound healing, and ambulation after knee disarticulation (KD). METHODS: Between July 1989 and October 2015, 153 KDs in 138 patients were performed at Nij Smellinghe Hospital, Drachten. Data were retrieved from hospital medical records. Wound healing was analyzed using nonparametric tests. Ambulation was recorded according to the Special Interest Group Amputation Medicine Workgroup Amputation and Prosthetics mobility scale...
September 2017: Journal of Vascular Surgery
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