Yan Liu, Xin-Yuan Li, Jia-Tong Wu, Han Wang, Xin Meng, Hai-Dan Zou, Juan Pan, Wei Guan, Adnan Mohammed Algradi, Anam Naseem, Hai-Xue Kuang, Bing-You Yang
A total of 14 previously undescribed steroidal saponins named capsicsaponins A-N were isolated from the leaves of Solanum capsicoides, encompassing various types, including cholesterol derivatives and pseudospirostanol saponins. The structures of all compounds were determined through comprehensive analysis of spectroscopic data (1D NMR and 2D NMR), along with physicochemical analysis methods (acid hydrolysis, OR, and UV). Moreover, in the H2 O2 -induced pheochromocytoma cell line model, compounds 1-14 were screened for their neuroprotective effects on cells...
April 12, 2024: Phytochemistry