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Cervical ectopic

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https://www.readbyqxmd.com/read/29776698/transoral-videolaryngoscopic-surgery-for-papillary-carcinoma-arising-in-lingual-thyroid
#1
Chisato Mogi, Hirotaka Shinomiya, Natsumi Fujii, Tomoyuki Tsuruta, Naruhiko Morita, Tatsuya Furukawa, Masanori Teshima, Maki Kanzawa, Mitsuyoshi Hirokawa, Naoki Otsuki, Ken-Ichi Nibu
Carcinoma arising in lingual thyroid is an extremely rare entity accounting for only 1% of all reported ectopic thyroids. Here, we report a case of carcinoma arising in lingual thyroid, which has been successfully managed by transoral resection and bilateral neck dissections. A lingual mass 4-cm in diameter with calcification was incidentally detected by computed tomography at medical check-up. No thyroid tissue was observed in normal position. Ultrasound examination showed bilateral multiple lymphadenopathies...
May 15, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29743554/gadd45%C3%AE-sensitizes-cervical-cancer-cells-to-radiotherapy-via-increasing-cytoplasmic-ape1-level
#2
Qing Li, Xi Wei, Zhi-Wei Zhou, Shu-Nan Wang, Hua Jin, Kui-Jun Chen, Jia Luo, Kenneth D Westover, Jian-Min Wang, Dong Wang, Cheng-Xiong Xu, Jin-Lu Shan
Radioresistance remains a major clinical challenge in cervical cancer therapy. However, the mechanism for the development of radioresistance in cervical cancer is unclear. Herein, we determined that growth arrest and DNA-damage-inducible protein 45α (GADD45α) is decreased in radioresistant cervical cancer compared to radiosensitive cancer both in vitro and in vivo. In addition, silencing GADD45α prevents cervical cancer cells from undergoing radiation-induced DNA damage, cell cycle arrest, and apoptosis...
May 9, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29730079/hysteroscopic-management-of-cervical-pregnancy-case-series-and-review-of-the-literature
#3
Vasilios Tanos, Sayed ElAkhras, Baris Kaya
PURPOSE: To evaluate the hysteroscopic management on cervical pregnancy. MATERIALS AND METHODS: A case series report and literature review on patients with early first trimester cervical pregnancy (CP) treated by hysteroscopy. The symptoms upon admission, β-hCG levels, hysteroscopy technique, blood loss and operation outcomes were presented. RESULTS: Four patients with early CP between 5-7 weeks were successfully managed with operative hysteroscopy...
May 3, 2018: Journal of Gynecology Obstetrics and Human Reproduction
https://www.readbyqxmd.com/read/29713741/magnetic-resonance-imaging-of-common-uncommon-and-rare-implantation-sites-in-ectopic-pregnancy
#4
REVIEW
Subramaniyan Ramanathan, Vineetha Raghu, Sushila B Ladumor, Anita N Nagadi, Yegu Palaniappan, Vikram Dogra, Nicola Schieda
OBJECTIVE: To review the MRI appearances of tubal and non-tubal implantation sites in ectopic pregnancy. CONCLUSION: Transvaginal ultrasound is the primary imaging modality in ectopic pregnancy and MRI is used as a problem-solving tool in selected indications as detailed in the article. MRI features of tubal, interstitial, cervical, cesarean scar, cornual, ovarian, abdominal, and heterotopic pregnancies are provided to familiarize the radiologists with their appearances thereby assisting them in making early and accurate diagnosis...
April 30, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29664545/pcr-diagnostics-of-chlamydia-trachomatis-in-asymptomatic-infection-by-women
#5
Magdalena Frej-Mądrzak, Anna Gryboś, Marian Gryboś, Dorota Teryks-Wołyniec, Agnieszka Jama-Kmiecik, Jolanta Sarowska, Irena Choroszy-Król
OBJECTIVES: Chlamydial infection is often asymptomatic. The lack of symptoms may result in the infection developing into a chronic. Chlamydial infections of the genitourinary system in women can lead to serious complications like PID, fallopian tubes infertility, ectopic pregnancy, and chronic pelvic pain. An infection of the genitourinary system does not cause any lasting immune resistance and does not protect against re-infection. The aim of this research was to conduct tests for Chlamydia trachomatis on healthy women without any genital system symptoms and to estimate the frequency of asymptomatic infections...
2018: Ginekologia Polska
https://www.readbyqxmd.com/read/29661236/clinical-analysis-of-50-patients-with-heterotopic-pregnancy-after-ovulation-induction-or-embryo-transfer
#6
Zaigui Wu, Xinmei Zhang, Ping Xu, Xiufeng Huang
OBJECTIVES: The purpose of this study was to evaluate the clinical characteristics, prenatal diagnosis, and management of patients with heterotopic pregnancy after ovulation induction or embryo transfer. METHODS: This was a retrospective study of fifty cases with heterotopic pregnancy, in which the fertilization way, type and number of embryo transferred, gestational age, clinical presentation and outcome of intrauterine, ultrasound presentation and site of ectopic pregnancy, bilateral fallopian tube and treatment were evaluated...
April 16, 2018: European Journal of Medical Research
https://www.readbyqxmd.com/read/29660208/mir-340-suppresses-the-metastasis-by-targeting-epha3-in-cervical-cancer
#7
Hemei Xiao, Lijie Yu, Fengdan Li, Haili Wang, Wenxiu Li, Xinxia He
MicroRNAs (miRNAs ) play key roles in cervical cancer metastasis progression. Accumulated evidences have revealed that miRNAs are related to the pathophysiological process. However, the role of miR-340 in cervical cancer and how it works is still not fully interpreted. Using qRT-PCR to examine the expression of miR-340 in cervical cancer tissues. Transwell migration and invasion experiments were used to detect the role of miR-340 in migration and invasion. Luciferase reporter assay, qRT-PCR and Western blot were used to detect the relationship between miR-340 and EphA3...
April 16, 2018: Cell Biology International
https://www.readbyqxmd.com/read/29626459/an-unusual-invasive-ectopic-thymoma-in-the-thyroid-and-anterior-mediastinum
#8
Haruaki Hino, Jun-Ichi Nitadori, Keiko Ohno, Seiji Kishimoto, Masatoki Takahashi, Mototsune Kakizaki, Tomio Arai, Nishimura Takashi, Jun Nakajima
An 81-year-old woman with a 2-year history of dysphagia detected a cervical mass. Computed tomography showed a thyroid tumor extending through the superior and anterior mediastinum. Incisional biopsy revealed a thymoma. Total resection of the thyroid and mediastinal tumor was performed. The thymoma invaded the anterior tracheal wall and left brachiocephalic vein. Pathological examination revealed thymoma type B1 concomitant with B2 and B3 (World Health Organization classification), Masaoka IVb and T3N2M0-IVb, with cervical lymph node metastasis...
April 4, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29607198/an-acquired-transposition-of-the-aortic-arch-secondary-to-large-esophageal-cancer-misdiagnosed-as-a-right-side-aortic-arch
#9
Yu Zheng, Xi-Wen Zhao, Han-Lu Zhang, Zi-Hao Wang, Yun Wang
The present study is the first reported case of a patient undergoing esophagectomy with ectopic aortic arch secondary to a large esophageal cancer, which was pre-operatively misdiagnosed with a right-side aortic arch (RAA). The patient, a 54-year-old male, was first admitted to our hospital for esophagectomy owing to esophageal squamous cancer and had complained of progressive dysphasia for 3 months. Chest computed tomography (CT) revealed a mass in the middle thoracic esophagus. Furthermore, the three-dimensional CT of the thoracic great arteries showed a possible RAA and a curved descending aorta...
February 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29582418/management-of-uterine-ectopic-pregnancy-local-versus-systemic-methotrexate
#10
Marianne Koch, Stephanie Schwab, Elias Meyer, Eliana Montanari, Yvonne Bader, Johannes Ott, Samir Helmy
INTRODUCTION: To compare ultrasound-guided local methotrexate (MTX) vs. systemic methotrexate in uterine ectopic pregnancy regarding the beta human chorionic gonadotropin (hCG) clearance duration. MATERIAL AND METHODS: Patients with interstitial pregnancy, cervical pregnancy or cesarean scar pregnancy were included. Methotrexate was administered locally ultrasound-guided (25 mg methotrexate fixed dose) or systemically (intramuscular; 50 mg/m2 body weight). Beta hCG clearance duration in days formed the main outcome measure...
March 27, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29572178/long-noncoding-rna-bdnf-as-is-downregulated-in-cervical-cancer-and-has-anti-cancer-functions-by-negatively-associating-with-bdnf
#11
Huimin Zhang, Caihong Liu, Ting Yan, Jun Wang, Wentong Liang
PURPOSE: We investigated expression and mechanism long noncoding RNA BDNF-AS in human cervical cancer (CC). METHODS: BDNF-AS expressions were examined by qPCR in CC cell lines and human CC tumors. CC cell lines, SiHa and DoTc2-4510 were transduced with lentivirus to ectopically overexpress BDNF-AS. Possible anti-cancer effects of BDNF overexpression were examined on CC in vitro proliferation and migration, and in vivo transplantation. Human BDNF gene expression was also examined in CC cell lines and tumors...
March 20, 2018: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/29563976/microrna-454-3p-inhibits-cervical-cancer-cell-invasion-and-migration-by-targeting-c-met
#12
Yan Guo, Min Tao, Min Jiang
Increasing evidence has demonstrated that microRNAs (miRNAs) have a crucial role in the initiation and progression of tumors. The present study aimed to investigate the expression and the role of miRNA-454-3p in human cervical cancer. Human cervical cancer cells were transfected with miRNA-454-3p mimics or negative control miRNA. MTT, Transwell and wound healing assays were performed to investigate the effects of miRNA-454-3p overexpression on cell proliferation, invasion and migration, respectively. The results indicated that miRNA-454-3p was down-regulated in human cervical cancer cell lines, while its ectopic overexpression significantly inhibited their proliferation, migration and invasion...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29556708/serial-uterine-artery-embolization-for-the-treatment-of-placenta-percreta-in-the-first-trimester-a-case-report
#13
John DeMeritt, Ethan Wajswol, Anoop Wattamwar, Babak Litkouhi, Ami Vaidya, Michael Sbarra, Stacy Zamudio, Rocio Acera Pozzi, Andrew Canning, John Woytanowski, Abdulla Al-Khan
Two patients with placenta percreta underwent uterine artery embolization (UAE) for abnormally invasive placenta (AIP) in the first trimester. Patient 1 had a 9-week cervical ectopic, while Patient 2 had a 9-week cesarean scar pregnancy. Elective termination of pregnancy was performed in both patients. UAE was performed with tris-acryl gelatin microspheres as well as gelfoam until stasis and was repeated in cases of revascularization. Both patients were followed with US/MRI/MRA scans and β-hCG levels. Revascularization occurred in both patients following UAE, requiring multiple embolizations to achieve complete placental involution...
March 19, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29538025/false-positive-results-in-18f-fluorocholine-pet-ct-for-a-thymoma-in-workup-of-a-hereditary-primary-hyperparathyroidism
#14
Léopoldine Bricaire, Capucine Richard, Mathieu Gauthé, Béatrix Cochand-Priollet, Sébastien Gaujoux
We present the case of a severe familial primary hyperparathyroidism related to a germline deletion in the HRPT2 (CDC73) gene. Morphological explorations revealed 2 potential hyperfunctioning parathyroid glands: a left cervical lesion on the neck ultrasound, and an ectopic mediastinal lesion on the parathyroid scintigraphy using Tc-methoxyisobutylisonitrile and on F-fluorocholine PET/CT. Surgery removal and histopathological examination determined that the mediastinal mass corresponded to a thymoma and the cervical lesion to a parathyroid adenoma...
May 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29537335/conservative-management-of-interstitial-pregnancies-experience-of-a-single-centre
#15
Semih Zeki Uludag, Mehmet Serdar Kutuk, Mehmet Dolanbay, Mahmut Tuncay Ozgun, Gunel Eliyeva, Ozguc Altun
The aim of this study was to compare the effect of local intracavitary methotrexate (MTX) injection and laparoscopic (L/S) cornuostomy in the treatment of interstitial pregnancy (IP) in terms of clinical and reproductive outcome. The data of patients with IP (n:10) who were treated between September 2011 and December 2016 with either an intra-amniotic MTX injection (n:7) or L/S cornuostomy (n:3) were retrospectively evaluated. All cases (7/7) in the local injection group and two (2/3) in the L/S group were successfully treated with the initial treatment...
March 14, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29483822/human-papillomavirus-types-16-and-18-early-expressed-proteins-differentially-modulate-the-cellular-redox-state-and-dna-damage
#16
Alfredo Cruz-Gregorio, Joaquín Manzo-Merino, María Cecilia Gonzaléz-García, José Pedraza-Chaverri, Omar Noel Medina-Campos, Mahara Valverde, Emilio Rojas, María Alexandra Rodríguez-Sastre, Claudia María García-Cuellar, Marcela Lizano
Oxidative stress has been proposed as a risk factor for cervical cancer development. However, few studies have evaluated the redox state associated with human papillomavirus (HPV) infection. The aim of this work was to determine the role of the early expressed viral proteins E1, E2, E6 and E7 from HPV types 16 and 18 in the modulation of the redox state in an integral form. Therefore, generation of reactive oxygen species (ROS), concentration of reduced glutathione (GSH), levels and activity of the antioxidant enzymes catalase and superoxide dismutase (SOD) and deoxyribonucleic acid (DNA) damage, were analysed in epithelial cells ectopically expressing the viral proteins...
2018: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/29449553/nuclear-factor-90-promotes-angiogenesis-by-regulating-hif-1%C3%AE-vegf-a-expression-through-the-pi3k-akt-signaling-pathway-in-human-cervical-cancer
#17
Wenqian Zhang, Zhengai Xiong, Tianqin Wei, Qiumeng Li, Ying Tan, Li Ling, Xiushan Feng
Vascular endothelial growth factor A (VEGF-A), a fundamental component of angiogenesis, provides nutrients and oxygen to solid tumors, and enhances tumor cell survival, invasion, and migration. Nuclear factor 90 (NF90), a double-stranded RNA-binding protein, is strongly expressed in several human cancers, promotes tumor growth by reducing apoptosis, and increasing cell cycle process. The mechanisms by which cervical cancer cells inducing VEGF-A expression and angiogenesis upon NF90 upregulation remain to be fully established...
February 15, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29433363/to-douche-or-not-to-douche-hygiene-habits-may-have-detrimental-effects-on-vaginal-microbiota
#18
Erdogan Aslan, Nadia Bechelaghem
The importance of a healthy vaginal micro-flora is indisputable. Therefore, intravaginal practices, such as vaginal douching (VD), may inhibit or lower the colonisation of beneficial Lactobacilli strains. Although the results of disrupted vaginal microbiota have been widely reported in the literature, direct microbicidal effects of products used for VD have been rarely studied. Moreover, there are certain studies advocating the beneficial effects of VD. This in vitro study was designed to provide more evidence to help health care givers in disseminating the knowledge that VD might have detrimental effects on vaginal microbiota...
February 13, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29417013/determinants-of-menstrual-hygiene-among-school-going-adolescent-girls-in-a-rural-area-of-west-bengal
#19
Ishita Sarkar, Madhumita Dobe, Aparajita Dasgupta, Rivu Basu, Bhaskar Shahbabu
Background: Menstrual hygiene is a neglected issue in rural India. Lack of menstrual hygiene in adolescent girls can make them susceptible to various morbidities, for example, reproductive tract infection and urinary tract infection and their long-term consequences, for example, cervical cancer, infertility, and ectopic pregnancy. This study aims to find out the determinants of menstrual hygiene among the school going adolescent girls in a rural area of West Bengal. Objectives: To elicit the menstrual hygiene practices among the study population and to find out the association of poor menstrual hygiene practices with sociodemographic factors, such as age, occupation and education of the parents, housing, and presence of sanitary toilet...
July 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29408754/elective-abortion-clinical-practice-guidelines-from-the-french-college-of-gynecologists-and-obstetricians-cngof
#20
REVIEW
Christophe Vayssière, Adrien Gaudineau, Luisa Attali, Karima Bettahar, Sophie Eyraud, Philippe Faucher, Patrick Fournet, Danielle Hassoun, Marie Hatchuel, Christian Jamin, Brigitte Letombe, Teddy Linet, Marie Msika Razon, Alexandra Ohanessian, Hélène Segain, Solène Vigoureux, Norbert Winer, Sophie Wylomanski, Aubert Agostini
The number of elective abortions has been stable for several decades. Many factors explain women's choice of abortion in cases of unplanned pregnancies. Early initiation of contraceptive use and a choice of contraceptive choices appropriate to the woman's life are associated with lower rates of unplanned pregnancies. Reversible long-acting contraceptives should be favored as first-line methods for adolescents because of their effectiveness (grade C). Ultrasound scan before an elective abortion must be encouraged but should not be obligatory (professional consensus)...
March 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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