Genki Mizuno, Hiroya Yamada, Eiji Munetsuna, Yoshitaka Ando, Atsushi Teshigawara, Manaka Ito, Itsuki Kageyama, Yuki Nouchi, Takuya Wakasugi, Tomohide Sakakibara, Mirai Yamazaki, Hiroaki Ishikawa, Koji Suzuki, Shuji Hashimoto, Koji Ohashi
High-fructose corn syrup (HFCS) is consumed worldwide. However, it has been demonstrated that an increased intake of sweetened beverages, including those sweetened using fructose, is associated with the development of childhood obesity. It is unknown why the negative effects of fructose are stronger in young persons than in elderly individuals. In recent years, mitochondria have been identified as 1 of the targets of the negative effects of fructose; they possess their own genome called mitochondrial DNA (mtDNA), which encodes genes involved in metabolic functions...
December 21, 2022: Nutrition Research