keyword
MENU ▼
Read by QxMD icon Read
search

Necrotizing pancreatitis

keyword
https://www.readbyqxmd.com/read/29210905/endoscopic-transluminal-debridement-of-the-pancreas
#1
George Rabbat, Jaime Teran Rocha
Most patients with acute pancreatitis will develop edematous pancreatitis with a mild course and spontaneous resolution within several days to a few weeks. However, about 20% of patients will develop necrotizing pancreatitis, which carries a high mortality. This case report focuses on a patient with infected necrosis of the pancreas, which is managed with endoscopic transluminal debridement, a safe alternative to open surgery.
December 2017: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/29209119/how-severe-is-moderately-severe-acute-pancreatitis-clinical-validation-of-revised-2012-atlanta-classification
#2
Povilas Ignatavicius, Aiste Gulla, Karolis Cernauskis, Giedrius Barauskas, Zilvinas Dambrauskas
AIM: To explore the outcomes and the appropriate treatment for patients with moderately severe acute pancreatitis (AP). METHODS: Statistical analysis was performed on data from the prospectively collected database of 103 AP patients admitted to the Department of Surgery, Hospital of Lithuanian University of Health Sciences in 2008-2013. All patients were confirmed to have the diagnosis of AP during the first 24 h following admission. The severity of pancreatitis was assessed by MODS and APACHE II scale...
November 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29200128/tro40303-ameliorates-alcohol-induced-pancreatitis-through-reduction-of-fatty-acid-ethyl-ester-induced-mitochondrial-injury-and-necrotic-cell-death
#3
Muhammad Ahsan Javed, Li Wen, Muhammad Awais, Diane Latawiec, Wei Huang, Michael Chvanov, Sophie Schaller, Thierry Bordet, Magali Michaud, Rebecca Pruss, Alexei Tepikin, David Criddle, Robert Sutton
OBJECTIVES: Mitochondrial permeability transition pore inhibition is a promising approach to treat acute pancreatitis (AP). We sought to determine (i) the effects of the mitochondrial permeability transition pore inhibitor 3,5-seco-4-nor-cholestan-5-one oxime-3-ol (TRO40303) on murine and human pancreatic acinar cell (PAC) injury induced by fatty acid ethyl esters (FAEEs) or taurolithocholic acid-3-sulfate and (ii) TRO40303 pharmacokinetics and efficacy in experimental alcoholic AP (FAEE-AP)...
December 2, 2017: Pancreas
https://www.readbyqxmd.com/read/29199182/delayed-diagnosis-and-treatment-of-high-grade-blunt-pancreatic-trauma-case-report-and-review-of-literature
#4
Myftar Torba, Arben Gjata, Francesco Rulli, Ilir Kajo, Sotir Ceka, Tajar Asqeri
INTRODUCTION: Despite technological advancement, high grade pancreatic injuries following blunt abdominal trauma continues to remain a disease that is associated with high morbidity and mortality rates, particularly in cases of delayed diagnosis. The aim of this paper was the presentation of delayed diagnosis and treatment peculiarities of high grade pancreatic trauma and a review of literature. CASE REPORT: A 55-years old man, involved in motor vehicle crashes, was referred to our level I trauma center...
November 29, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29198548/embolization-of-arterial-gastrointestinal-hemorrhage-with-fuaile-medical%C3%A2-adhesive
#5
Min Xu, Xiaoli Zhu, Yizhi Liu, Zhi Li, Tianzhi An, Tianpeng Jiang, Jie Song, Lizhou Wang, Shi Zhou, Caifang Ni
BACKGROUND: To investigate the safety and effectiveness of Fuaile medical adhesive (FAL) with superselective catheterization in endovascular embolotherapy for the treatment of gastrointestinal hemorrhage (GIH) that was unresponsive to internal medicine treatment and gastroscopy management. METHODS: A total of 25 patients with GIH, confirmed using angiography but with failed results after internal medicine treatment or gastroscopy were retrospectively analyzed. A mixture of lipiodol and FAL (1:1) was used to embolize the bleeding vessels...
November 30, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29182741/off-label-use-of-thoracic-aortic-endovascular-stent-grafts-to-simplify-difficult-resections-and-procedures-in-general-thoracic-surgery
#6
Tanja Walgram, Nicolas Attigah, Igor Schwegler, Markus Weber, Omer Dzemali, Christian Berthold, Dirk Wagnetz, Giovanni L Carboni
OBJECTIVES: Tumour infiltration, or gross infectious involvement of the thoracic aortic wall, poses a significant intraoperative risk for fatal bleeding and therefore could compromise adequate resection or efficient surgical management of pleural infection in a considerable amount of cases. We present 3 successful cases of off-label thoracic aortic endografting to safeguard thoracic aortic wall integrity. METHODS: After all patients received thoracic stent grafts through femoral access into the descending aorta, the first patient underwent a resection of a locally advanced squamous cell carcinoma of the left inferior lobe cT4cN0-1cM0 after neoadjuvant chemoradiation, which had infiltrated the descending aortic wall...
November 22, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29180851/differences-of-statin-activity-in-2d-and-3d-pancreatic-cancer-cell-cultures
#7
Miglė Paškevičiūtė, Vilma Petrikaitė
Purpose: To evaluate the anticancer activity of lovastatin (LOVA), mevastatin (MEVA), pitavastatin (PITA), and simvastatin (SIMVA) in 2D and 3D models of three human pancreatic cancer cell lines (BxPC-3, MIA PaCa-2, and PANC-1). Methods: The effect of statins on cell viability was estimated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test. The activity of statins in 3D pancreatic cancer cell cultures was examined by measuring the size change of spheroids...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/29167024/evolving-treatment-of-necrotizing-pancreatitis
#8
Alexandra M Roch, Thomas Maatman, Rose A Carr, Jeffrey J Easler, C Max Schmidt, Michael G House, Attila Nakeeb, Eugene P Ceppa, Nicholas J Zyromski
BACKGROUND: Over the past decade, the treatment of necrotizing pancreatitis (NP) has incorporated greater use of minimally invasive techniques, including percutaneous drainage and endoscopic debridement. No study has yet compared outcomes of patients treated with all available techniques. We sought to evaluate the evolution of NP treatment at our high volume pancreas center. We hypothesized that minimally invasive techniques (medical only, percutaneous, and endoscopic) were used more frequently in later years...
November 14, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/29166257/raoultella-planticola-a-rare-cause-of-wound-infection
#9
Shana S Kalaria, Kristina Elliott, Neal Combs, Linda G Phillips
Raoultella planticola is a gram-negative, aerobic, rod bacterium commonly found in the environment, particularly in water, soil, and fish. This organism has been found to cause a variety of infections, such as necrotizing fasciitis, cystitis, cholecystitis, pancreatitis, hepatic disease, and soft tissue infections. The authors report the case of a 73-year-old-woman who presented with a R planticola wound infection of her left lower extremity after a dog scratch. She was treated successfully with local wound care using dehydrated human amnion/chorion and oral levofloxacin...
November 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29147123/acute-necrotizing-pancreatitis-following-coronary-artery-angiography-a-case-report
#10
Majid Hajimaghsoudi, Faezeh Zeinali, Mehrdad Mansouri, Mohammad Hosein Dehghani
BACKGROUND: Acute pancreatitis has different etiologies from biliary stone to metabolic disturbances. Coronary angiography is one of the newly understood etiologies. CASE REPORT: This paper is about a women suffering from acute pancreatitis after coronary angiography. CONCLUSION: Embolization of cholesterol crystals due to vessel wall trauma during coronary angiography as well as contrast medium are responsible for such side effect.
May 2017: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/29145291/early-enteral-nutrition-versus-delayed-enteral-nutrition-in-acute-pancreatitis-a-prisma-compliant-systematic-review-and-meta-analysis
#11
REVIEW
Ping Feng, Chenjian He, Guqing Liao, Yanming Chen
BACKGROUND: Whether early enteral nutrition (EEN) administration is more beneficial than delayed enteral nutrition (DEN) for patients with acute pancreatitis remains controversial. METHODS: This meta-analysis aimed to pool all relevant articles to evaluate the effects of EEN within 48 hours versus DEN beyond 48 hours on the clinical outcomes of patients with acute pancreatitis. We searched PubMed, Scopus, Embase, and Web of Science for all relevant studies and extracted the data concerning basic characteristics, complications, and mortality...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29121584/a-case-report-of-primary-pancreatic-leiomyosarcoma-requiring-six-additional-resections-for-recurrences
#12
Shinichiro Makimoto, Kotaro Hatano, Naoki Kataoka, Tomoyuki Yamaguchi, Masafumi Tomita, Eisei Nishino
INTRODUCTION: Primary pancreatic leiomyosarcoma is extremely rare. We report a case in which six additional resections were required to treat recurrent tumors in a 5-year period following the primary operation. PRESENTATION OF CASE: A 69-year-old man presented with a pancreatic tumor. Abdominal computed tomography scan showed a large heterogeneous mass with a necrotic area arising from the pancreatic body. We performed distal pancreatectomy, splenectomy, and wide resection of the transverse mesocolon...
October 27, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29118690/pneumoperitoneum-after-endoscopic-retrograde-cholangiopancreatography-due-to-rupture-of-intrahepatic-bile-ducts-and-glisson-s-capsule-in-hepatic-metastasis-a-case-report-and-review-of-literature
#13
Zubair Khan, Umar Darr, Mohamad Nawras, Muhammad Bawany, Jacob Bieszczad, Osama Alaradi, Ali Nawras
Introduction: Endoscopic retrograde cholangiopancreatography (ERCP) has been proven to be a safe and effective method for diagnosis and treatment of biliary and pancreatic disorders. Major complications of ERCP include pancreatitis, hemorrhage, cholangitis, and duodenal perforation. We report a third case in literature of pneumoperitoneum after ERCP due to rupture of intrahepatic bile ducts and Glisson's capsule in a peripheral hepatic lesion. Case Report: A 50-year-old male with a history of metastatic pancreatic neuroendocrine tumor and who had a partially covered metallic stent placed in the biliary tree 1 year ago presented to the oncology clinic with fatigue, abdominal pain, and hypotension...
September 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29113713/update-role-of-surgery-in-acute-necrotizing-pancreatitis
#14
I El Boukili, G Boschetti, H Belkhodja, V Kepenekian, P Rousset, G Passot
Acute necrotizing pancreatitis is a prevalent disease with high morbidity and mortality. The development of radiologic and endoscopic techniques to manage pancreatic necrosis commands a multidisciplinary approach, which has considerably decreased the need for laparotomy. The objective of this update is to define the role of surgery in the multidisciplinary approach to management of necrotizing acute pancreatitis.
November 4, 2017: Journal of Visceral Surgery
https://www.readbyqxmd.com/read/29113316/efficacy-of-sub-threshold-focused-ultrasound-irradiation-against-pancreatic-cancer-xenografts-evaluated-using-magnetic-resonance-imaging
#15
Rui Wang, Qian Guo, Yini Chen, Yihui Gao, Lei Wu, Bing Hu, Lixin Jiang
We investigated the efficacy and optimal period for using magnetic resonance imaging (MRI) to detect effects of sub-threshold focused ultrasound (FUS) irradiation. Nude mice bearing pancreatic cancer xenografts were subjected to MRI and pathology examnation before, and 24 h, 48 h, 2 weeks after irradiation, which were used to evaluate therapeutic effects of FUS. Tumor volumes were lower post-treatment than control group (P < 0.05). The T1WI turbo spin echo (T1WI-TSE) sequence was similar signal before and after treatment...
October 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/29109852/mortality-and-morbidity-in-necrotizing-pancreatitis-managed-on-principles-of-step-up-approach-7-years-experience-from-a-single-surgical-unit
#16
Deshpande Aparna, Sunil Kumar, Shukla Kamalkumar
AIM: To determine percentage of patients of necrotizing pancreatitis (NP) requiring intervention and the types of interventions performed. Outcomes of patients of step up necrosectomy to those of direct necrosectomy were compared. Operative mortality, overall mortality, morbidity and overall length of stay were determined. METHODS: After institutional ethics committee clearance and waiver of consent, records of patients of pancreatitis were reviewed. After excluding patients as per criteria, epidemiologic and clinical data of patients of NP was noted...
October 27, 2017: World Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29104650/predictive-factors-of-pancreatic-necrosectomy-following-percutaneous-catheter-drainage-as-a-primary-treatment-of-patients-with-infected-necrotizing-pancreatitis
#17
Xi Cao, Feng Cao, Ang Li, Xiang Gao, Xiao-Hui Wang, Dian-Gang Liu, Yu Fang, Dong-Hai Guo, Fei Li
Pancreatic necrosectomy (PN) following percutaneous catheter drainage (PCD) is an effective method of treating patients with necrotizing pancreatitis, however, the predictive factors for PN after PCD have not yet been identified. A total of 74 patients with suspected infected necrotizing pancreatitis (INP) and peripancreatic fluid collection were enrolled in the current study between October 2010 and October 2015. These patients received ultrasound or computer topography guided PCD followed by PN. Patients were divided into two groups: i) A PCD-alone group (n=32) and ii) a PCD+necrosectomy group (n=42)...
November 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29099712/influence-of-testosterone-on-morphological-changes-in-pancreatic-islets-and-liver-tissue-of-rats-with-alloxan-induced-diabetes
#18
S Kandelaki, M Kharabadze, I Sikharulidze, M Velijanashvili, M Kakabadze, D Kordzaia
The role of exogenous testosterone (methyltrienolone) in the repair of damaged pancreatic islet and liver cells during alloxan diabetes was studied. Modeling of diabetes was performed through single intraperitoneal injection of Alloxan, with the dose 2 mg per 10 g of body weight. Pancreatic and liver tissues were investigated microscopically using 3-4 µm slices embedded in paraffin and stained with hematoxylin and eosin. Software Adobe Photoshop was used to measure the areas of pancreatic islets as well as areas of necrotic foci in these islets of animals with Alloxan-induced experimental diabetes...
October 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29099617/minimally-invasive-pancreatic-necrosectomy-a-technical-pictorial-review
#19
Gregory C Makris, Teikchoon See, Andrew Winterbottom, Asif Jah, Nadeem Shaida
Necrotizing pancreatitis is the most severe form of acute pancreatitis, which is associated with significant mortality and morbidity. Open necrosectomy has been one of the treatment modalities, however, several studies have shown high mortality rates to those undergoing early surgery. In this pictorial review we are presenting a minimally invasive procedure for the debridement of the necrotic pancreatic tissue. We will discuss the current evidence around the use of this procedure and we will describe the technique of minimally invasive pancreatic necrosectomy...
November 3, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29093619/short-and-long-term-results-of-endoscopic-ultrasound-guided-transmural-drainage-for-pancreatic-pseudocysts-and-walled-off-necrosis
#20
Yuto Watanabe, Rintaro Mikata, Shin Yasui, Hiroshi Ohyama, Harutoshi Sugiyama, Yuji Sakai, Toshio Tsuyuguchi, Naoya Kato
AIM: To evaluate the short- and long-term results of endoscopic ultrasound-guided transmural drainage (EUS-GTD) for pancreatic fluid collection (PFC) and identify the predictive factors of treatment outcome for walled-off necrosis (WON) managed by EUS-GTD alone. METHODS: We investigated 103 consecutive patients with PFC who underwent EUS-GTD between September 1999 and August 2015. Patients were divided into four groups as follows: WON (n = 40), pancreatic pseudocyst (PPC; n = 11), chronic pseudocyst (n = 33), and others (n = 19)...
October 21, 2017: World Journal of Gastroenterology: WJG
keyword
keyword
9808
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"