Deepika N P, Mohammed Shameer Kondengadan, Sherouk Hussein Sweilam, Md Habibur Rahman, K M Muhasina, Puja Ghosh, Divya Bhargavi, Divya Jyothi Palati, Fathi Maiz, B Duraiswamy
Neurodegenerative disease (ND) is a clinical condition in which neurons degenerate with a consequent loss of functions in the affected brain region. Parkinson's disease (PD) is the second most progressive ND after Alzheimer's disease (AD), which affects the motor system and is characterized by the loss of dopaminergic neurons from the nigrostriatal pathway in the midbrain, leading to bradykinesia, rigidity, resting tremor, postural instability and non-motor symptoms such as cognitive declines, psychiatric disturbances, autonomic failures, sleep difficulties, and pain syndrome...
October 8, 2022: Biotechnology & Genetic Engineering Reviews