keyword
https://read.qxmd.com/read/38650940/longitudinal-cytokine-and-multi-modal-health-data-of-an-extremely-severe-me-cfs-patient-with-hsd-reveals-insights-into-immunopathology-and-disease-severity
#1
JOURNAL ARTICLE
Fereshteh Jahanbani, Justin Cyril Sing, Rajan Douglas Maynard, Shaghayegh Jahanbani, Janet Dafoe, Whitney Dafoe, Nathan Jones, Kelvin J Wallace, Azuravesta Rastan, Holden T Maecker, Hannes L Röst, Michael P Snyder, Ronald W Davis
INTRODUCTION: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) presents substantial challenges in patient care due to its intricate multisystem nature, comorbidities, and global prevalence. The heterogeneity among patient populations, coupled with the absence of FDA-approved diagnostics and therapeutics, further complicates research into disease etiology and patient managment. Integrating longitudinal multi-omics data with clinical, health,textual, pharmaceutical, and nutraceutical data offers a promising avenue to address these complexities, aiding in the identification of underlying causes and providing insights into effective therapeutics and diagnostic strategies...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38650575/heterologous-expression-and-enzymatic-characteristics-of-sulfatase-from-lactobacillus-plantarum-dy-1
#2
JOURNAL ARTICLE
Zhangchen Cheng, Beiqi Wu, Juan Bai, Songtao Fan, Maria Daglia, Jiaying Li, Yansheng Zhao, Yufeng He, Lin Zhu, Xiang Xiao
Barley, rich in bioactive components including dietary fiber, polyphenolic compounds and functional proteins, exhibits health benefits such as regulating glucose and lipid metabolism. Previous studies have found that the content and composition of free phenolic acids in barley may be significantly changed by fermentation with the laboratory patented strain Lactobacillus plantarum dy-1 ( L. p dy-1), but the mechanism of enzymatic release of phenolic acid remains to be elucidated. Based on this, this study aimed to identify the key enzyme in L...
April 23, 2024: Food & Function
https://read.qxmd.com/read/38649546/microplastics-and-associated-polycyclic-aromatic-hydrocarbons-in-surface-water-and-sediment-of-the-bay-of-bengal-coastal-area-india-sources-pathway-and-ecological-risk
#3
JOURNAL ARTICLE
Kalpana Patidar, Balram Ambade, Mohammed Alshehri
In the aquatic environment around the world, microplastic contamination has been a common and ongoing issue. Particularly, the ability of microplastics to absorb persistent organic pollutants (POPs) and then transmit these POPs to aquatic creatures has attracted a lot of interest. A stereomicroscope was used to detect the size, shape, and color of the microplastics (MPs), and Fourier Transform Infrared (FTIR) spectroscopy was used to identify the polymer composition of the MPs. To address MP transit, destiny, and mitigation, a study of MP pollution coastal areas is required...
April 22, 2024: Environmental Geochemistry and Health
https://read.qxmd.com/read/38649076/caffeic-acid-combined-with-arabinoxylan-or-%C3%AE-glucan-attenuates-diet-induced-obesity-in-mice-via-modulation-of-gut-microbiota-and-metabolites
#4
JOURNAL ARTICLE
Wei Fang, Mingyu Jin, Wentao Qi, Chunli Kong, Ge Song, Wenting Peng, Yong Wang
Polyphenols and dietary fibers in whole grains are important bioactive compounds to reduce risks for obesity. However, whether the combination of the two components exhibits a stronger anti-obesity effect remains unclear. Caffeic acid is a major phenolic acid in cereals, and arabinoxylan and β-glucan are biological macromolecules with numerous health benefits. Here, we investigated the effect of caffeic acid combined with arabinoxylan or β-glucan on glucose and lipid metabolism, gut microbiota, and metabolites in mice fed a high-fat diet (HFD)...
April 20, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38646701/a-liquid-metal-polypyrrole-electrospun-tpu-composite-conductive-network-for-highly-sensitive-strain-sensing-in-human-motion-monitoring
#5
JOURNAL ARTICLE
Juan Du, Qinghui Han, Aibing Chen
Developing soft wearable sensors with high sensitivity, low cost, and a wide monitoring range is crucial for monitoring human health. Despite advances in strain sensor technology, achieving high sensitivity and a wide operating range in a single device remains a major challenge in its design and preparation. Herein, a liquid metal (LM) is innovatively ultrasonically anchored to the gaps and surfaces of thermoplastic polyurethane (TPU) electrospun fibers, and then a conductive pathway is constructed through polypyrrole (PPy) self-polymerization to prepare a composite film...
April 22, 2024: Journal of Materials Chemistry. B, Materials for Biology and Medicine
https://read.qxmd.com/read/38646106/editorial-new-advances-in-dietary-fibers-and-their-role-in-metabolic-digestive-and-immune-health
#6
EDITORIAL
Junrui Cheng, Aylin Sahin, Changling Hu, Renee Korczak, Jing Zhou
No abstract text is available yet for this article.
2024: Frontiers in Nutrition
https://read.qxmd.com/read/38644380/effects-of-environmental-exposure-to-iron-powder-on-healthy-and-elastase-exposed-mice
#7
JOURNAL ARTICLE
Thiago Tafarel Galli, Elaine Cristina de Campos, Leandro do Nascimento Camargo, Silvia Fukuzaki, Tabata Marayama Dos Santos, Sara Sumie Sobral Hamaguchi, Suellen Karoline Moreira Bezerra, Fabio José Alencar Silva, Bianca Goulart Rezende, Fernanda Tenório Quirino Dos Santos Lopes, Clarice Rosa Olivo, Beatriz Mangueira Saraiva-Romanholo, Carla Máximo Prado, Edna Aparecida Leick, Christine Laure Marie Bourotte, Isabela Judith Martins Benseñor, Paulo Andrade Lotufo, Renato Fraga Righetti, Iolanda Fátima Lopes Calvo Tibério
Prolonged exposure to iron powder and other mineral dusts can threaten the health of individuals, especially those with COPD. The goal of this study was to determine how environmental exposure to metal dust from two different mining centers in Brazil affects lung mechanics, inflammation, remodeling and oxidative stress responses in healthy and elastase-exposed mice. This study divided 72 male C57Bl/6 mice into two groups, the summer group and the winter group. These groups were further divided into six groups: control, nonexposed (SAL); nonexposed, given elastase (ELA); exposed to metal powder at a mining company (SAL-L1 and ELA-L1); and exposed to a location three miles away from the mining company (SAL-L2 and ELA-L2) for four weeks...
April 21, 2024: Scientific Reports
https://read.qxmd.com/read/38644018/evaluation-of-laboratory-and-environmental-exposure-systems-for-protein-modification-upon-gas-pollutants-and-environmental-factors
#8
JOURNAL ARTICLE
Zhiwei Pan, Shiyi Wu, Qiaoze Zhu, Fobang Liu, Yongjian Liang, Chenglei Pei, Haoyu Jiang, Yingyi Zhang, Senchao Lai
Chemical modifications of proteins induced by ambient ozone (O3 ) and nitrogen oxides (NOx ) are of public health concerns due to their potential to trigger respiratory diseases. The laboratory and environmental exposure systems have been widely used to investigate their relevant mechanism in the atmosphere. Using bovine serum albumin (BSA) as a model protein, we evaluated the two systems and aimed to reduce the uncertainties of both the reactants and products in the corresponding kinetic study. In the laboratory simulation system, the generated gaseous pollutants showed negligible losses...
September 2024: Journal of Environmental Sciences (China)
https://read.qxmd.com/read/38643621/remediation-of-oily-produced-water-from-high-salinity-oilfield-using-a-low-cost-high-alumina-calcium-bentonite-hollow-fiber-membrane
#9
JOURNAL ARTICLE
Mohamad Izrin Mohamad Esham, Abdul Latif Ahmad, Mohd Hafiz Dzarfan Othman, Mohd Ridhwan Adam
Discharging improperly treated oily-produced water (OPW) into the environment can have significant negative impacts on environmental sustainability. It can lead to pollution of water sources, damage to aquatic ecosystems and potential health hazards for individuals living in the affected areas. Ceramic hollow fiber membrane (CHFM) technology is one of the most effective OPW treatment methods for achieving high oil removal efficiency while maintaining membrane water permeability. In this study, low-cost calcium bentonite hollow fiber membranes (CaB-HFMs) were prepared from high-alumina calcium bentonite clay with various preparation parameters, including calcium bentonite content, sintering temperature, air gap distance and bore fluid rate...
April 20, 2024: Journal of Environmental Management
https://read.qxmd.com/read/38639907/maximization-of-brackish-water-productivity-for-the-sustainable-production-of-striped-catfish-pangasianodon-hypophthalmus-and-grain-sorghum-sorghum-bicolor-l-moench-cultivated-under-an-integrated-aquaculture-agriculture-system
#10
JOURNAL ARTICLE
Fahad Kimera, Muziri Mugwanya, Khaled Madkour, Mahmoud A O Dawood, Hani Sewilam
Freshwater scarcity, salinity, and poor soil fertility are the major challenges affecting both food and feed productions in arid and semi-arid regions of the world. Utilization of brackish water in the production of saline-tolerant fish and valuable field crops under an integrated system is promising in the maximization of yield per crop. The aim of this study, therefore, was to (1) assess the effect of saline aquaculture wastewater on the growth, yield, forage quality, and nutritive composition of sorghum seeds and (2) assess the effect of different water qualities on the survival, growth performance, and health status of Pangasianodon hypophthalmus...
April 19, 2024: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38639293/genetic-characterization-of-pediatric-sari-associated-human-adenoviruses-in-eight-chinese-provinces-during-2017-2021
#11
JOURNAL ARTICLE
Jianlin Cai, Ying Liu, Cheng Qian, Yixuan Gao, Sheng Zhao, Yingwei Ma, Xingyu Xiang, Jing Xu, Feng Zhang, Maozhong Li, Hongmei Xu, Qi Li, Chongyang Li, Yitong Lin, Baicheng Xia, Aili Cui, Yan Zhang, Zhen Zhu, Naiying Mao
Human adenovirus (HAdV) is a significant viral pathogen causing severe acute respiratory infections (SARIs) in children. To improve the understanding of type distribution and viral genetic characterization of HAdV in severe cases, this study enrolled 3404 pediatric SARI cases from eight provinces of China spanning 2017-2021, resulting in the acquisition of 112 HAdV strains. HAdV-type identification, based on three target genes (penton base, hexon, and fiber), confirmed the diversity of HAdV types in SARI cases...
April 2024: Journal of Medical Virology
https://read.qxmd.com/read/38638069/grape-seed-proanthocyanidin-extract-promotes-skeletal-muscle-fiber-type-transformation-through-modulation-of-cecal-microbiota-and-enhanced-butyric-acid-production
#12
JOURNAL ARTICLE
Yiqiang Li, Xiaoling Chen, Jun He, Ping Zheng, Yuheng Luo, Bing Yu, Daiwen Chen, Zhiqing Huang
The conversion of fast-twitch fibers into slow-twitch fibers within skeletal muscle plays a crucial role in improving physical stamina and safeguarding against metabolic disorders in individuals. Grape seed proanthocyanidin extract (GSPE) possesses numerous pharmacological and health advantages, effectively inhibiting the onset of chronic illnesses. However, there is a lack of research on the specific mechanisms by which GSPE influences muscle physiology and gut microbiota. This study aims to investigate the role of gut microbiota and their metabolites in GSPE regulation of skeletal muscle fiber type conversion...
April 18, 2024: Journal of Food Science
https://read.qxmd.com/read/38637421/impact-of-different-forms-of-selenium-supplementation-on-growth-and-physiological-performance-of-new-zealand-white-rabbits
#13
REVIEW
Kout-Elkloub M El Moustafa, Hoda M El-Hosseiny, G F Shaheen, E M El-Kotamy, Abd Elghani Ghoniem, G E Younan, M M El-Nahrawy, Mona E Farag, Manal S Mohamed
Forty-eight weaned male New Zealand White rabbits aged 6 weeks with an initial body weight of (709.67 ± 13 g) were randomly divided into six experimental groups (8 rabbits each) for 6-14 weeks of age experimental periods. The present study was planned to evaluate the effect of using different forms of Selenium element (inorganic, nanoparticles and organic) as dietary supplementation on productive performance of rabbits. Six experimental groups in completely randomized design were used...
April 19, 2024: Tropical Animal Health and Production
https://read.qxmd.com/read/38637108/the-infant-gut-microbiota-as-the-cornerstone-for-future-gastrointestinal-health
#14
JOURNAL ARTICLE
Chiara Tarracchini, Christian Milani, Gabriele Andrea Lugli, Leonardo Mancabelli, Francesca Turroni, Douwe van Sinderen, Marco Ventura
The early postnatal period represents a critical window of time for the establishment and maturation of the human gut microbiota. The gut microbiota undergoes dramatic developmental changes during the first year of life, being influenced by a variety of external factors, with diet being a major player. Indeed, the introduction of complementary feeding provides novel nutritive substrates and triggers a shift from milk-adapted gut microbiota toward an adult-like bacterial composition, which is characterized by an enhancement in diversity and proportions of fiber-degrading bacterial genera like Ruminococcus, Prevotella, Eubacterium, and Bacteroides genera...
2024: Advances in Applied Microbiology
https://read.qxmd.com/read/38636102/substrate-free-transfer-of-silicon-and-metallic-based-strain-sensors-on-textile-and-in-composite-material-for-structural-health-monitoring
#15
JOURNAL ARTICLE
Gaëtan Herry, Jean-Charles Fustec, France Le Bihan, Maxime Harnois
New technologies to integrate electronics and sensors on or into objects can support the growth of embedded electronics. The method proposed in this paper has the huge advantage of being substrate-free and applicable to a wide range of target materials such as fiber-based composites, widely used in manufacturing, and for which monitoring applications such as fatigue, cracks, and deformation detection are crucial. Here, sensors are first fabricated on a donor substrate using standard microelectronic processes and then transferred to the host material by direct transfer printing...
April 18, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38635155/characterization-of-a-symbiotic-beverage-based-on-water-soluble-soybean-extract-fermented-by-lactiplantibacillus-plantarum-atcc-8014
#16
JOURNAL ARTICLE
Fernanda Weber Bordini, Júlia Cristina Fernandes, Viviane Lívia Carvalho de Souza, Elaine Cristina Galhardo, Ismael Maciel de Mancilha, Maria das Graças de Almeida Felipe
The health benefits of functional foods are associated with consumer interest and have supported the growth of the market for these types of foods, with emphasis on the development of new formulations based on plant extracts. Therefore, the present study aimed to characterize a symbiotic preparation based on water-soluble soy extract, supplemented with inulin and xylitol and fermented by Lactiplantibacillus plantarum ATCC 8014. Regarding nutritional issues, the symbiotic formulation can be considered a source of fiber (2 g/100 mL) and proteins (2...
April 18, 2024: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://read.qxmd.com/read/38633603/role-of-dietary-fiber-and-lifestyle-modification-in-gut-health-and-sleep-quality
#17
JOURNAL ARTICLE
Amjad Ali Bacha, Muhammad Suhail, Fuad A Awwad, Emad A A Ismail, Hijaz Ahmad
Dietary fiber has an immense role in the gut microbiome by modulating juvenile growth, immune system maturation, glucose, and lipid metabolism. Lifestyle changes might disrupt gut microbiota symbiosis, leading to various chronic diseases with underlying inflammatory conditions, obesity, and its associated pathologies. An interventional study of 16 weeks examined the impact of psyllium husk fiber with and without lifestyle modification on gut health and sleep quality in people with central obesity (men = 60 and women = 60), those aged from 40 to 60 years, those having WC ≥ 90 cm (men) and WC ≥ 80 cm (women), and no history of any chronic disease or regular medication...
2024: Frontiers in Nutrition
https://read.qxmd.com/read/38632299/longitudinal-changes-in-optic-disc-cupping-from-the-baseline-in-chiasmal-lesion-optic-neuropathy-and-glaucoma
#18
JOURNAL ARTICLE
Eun Jung Lee, Jong Chul Han, Mira Kang, Doo-Sik Kong, Sang Duk Hong, Kyung-Ah Park, Changwon Kee
We aimed to investigate the changes in cupping in chiasmal lesion optic neuropathy (chON) compared to baseline optic disc and glaucoma. We used a novel study design to enroll patients who had fundus photographs incidentally taken during routine health check-ups prior to the onset of optic neuropathy. In 31 eyes (21 patients) with chON and 33 eyes (30 patients) with glaucoma, we investigated the change in cup-to-disc (C/D) area from the baseline to overt cupping using flicker analysis. Compared to the baseline, 23 eyes (74...
April 17, 2024: Scientific Reports
https://read.qxmd.com/read/38630507/causal-selection-of-covariates-in-regression-calibration-for-mismeasured-continuous-exposure
#19
JOURNAL ARTICLE
Wenze Tang, Donna Spiegelman, Xiaomei Liao, Molin Wang
Regression calibration as developed by Rosner, Spiegelman, and Willett is used to adjust the bias in effect estimates due to measurement error in continuous exposures. The method involves two models: a measurement error model relating the mismeasured exposure to the true (or gold-standard) exposure and an outcome model relating the mismeasured exposure to the outcome. However, no comprehensive guidance exists for determining which covariates should be included in each model. In this article, we investigate the selection of the minimal and most efficient covariate adjustment sets under a causal inference framework...
May 1, 2024: Epidemiology
https://read.qxmd.com/read/38630354/oculomics-a-crusade-against-the-four-horsemen-of-chronic-disease
#20
REVIEW
Emily J Patterson, Alistair D Bounds, Siegfried K Wagner, Richard Kadri-Langford, Robin Taylor, Dan Daly
Chronic, non-communicable diseases present a major barrier to living a long and healthy life. In many cases, early diagnosis can facilitate prevention, monitoring, and treatment efforts, improving patient outcomes. There is therefore a critical need to make screening techniques as accessible, unintimidating, and cost-effective as possible. The association between ocular biomarkers and systemic health and disease (oculomics) presents an attractive opportunity for detection of systemic diseases, as ophthalmic techniques are often relatively low-cost, fast, and non-invasive...
April 17, 2024: Ophthalmology and Therapy
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