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https://www.readbyqxmd.com/read/29145290/effective-treatment-of-narcolepsy-like-symptoms-with-high-frequency-repetitive-transcranial-magnetic-stimulation-a-case-report
#1
Jian-Bo Lai, Mao-Mao Han, Yi Xu, Shao-Hua Hu
RATIONALE: Narcolepsy is a rare sleep disorder with disrupted sleep-architecture. Clinical management of narcolepsy lies dominantly on symptom-driven pharmacotherapy. The treatment role of repetitive transcranial magnetic stimulation (rTMS) for narcolepsy remains unexplored. PATIENT CONCERNS: In this paper, we present a case of a 14-year-old young girl with excessive daytime sleepiness (EDS), cataplexy and hypnagogic hallucinations. DIAGNOSES: After excluding other possible medical conditions, this patient was primarily diagnosed with narcolepsy...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29144628/overactive-bladder-syndrome-and-bladder-wall-thickness-in-patients-with-obstructive-sleep-apnea-syndrome
#2
Zahide Yilmaz, Bekir Voyvoda, Pinar Bekdik Şirinocak
OBJECTIVE: The main objective of the present study was to evaluate the presence of overactive bladder (OAB) syndrome, nocturia, urgency, and urge incontinence in patients with obstructive sleep apnea syndrome (OSAS), and measure bladder wall thickness (BWT) in these patients. MATERIALS AND METHODS: The patient group was composed of 38 patients with OSAS. The control group was composed of 15 healthy individuals. All patients were evaluated using the Epworth Sleepiness Scale (ESS) and Overactive Bladder Symptom Score (OABSS)...
November 19, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29129030/effects-of-cpap-and-mandibular-advancement-device-treatment-in-obstructive-sleep-apnea-patients-a-systematic-review-and-meta-analysis
#3
REVIEW
Martha Schwartz, Luis Acosta, Yuan-Lung Hung, Mariela Padilla, Reyes Enciso
The purpose of this review is to conduct a systematic review and meta-analysis comparing the effects of continuous positive airway pressure (CPAP) with a mandibular advancement device (MAD) in improving the quality of life (sleepiness, cognitive, and functional outcomes) in patients diagnosed with obstructive sleep apnea (OSA). Authors identified randomized, placebo-controlled studies from MEDLINE through PubMed, Web of Science, and the Cochrane Library. Studies were assessed for inclusion and exclusion criteria, as well as risk of bias...
November 11, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29121638/impact-of-inability-to-turn-in-bed-assessed-by-a-wearable-three-axis-accelerometer-on-patients-with-parkinson-s-disease
#4
Kenji Uchino, Makoto Shiraishi, Keita Tanaka, Masashi Akamatsu, Yasuhiro Hasegawa
BACKGROUND: Difficulty turning over in bed is a common night-time symptom in Parkinson's disease (PD). We aimed to quantitatively evaluate overnight turnover movements using a three-axis accelerometer and to investigate whether inability to turn in bed is related to daytime sleepiness, sleep quality, and depressive mood in PD patients. METHODS: We examined 64 patients with PD (mean age, 73.3±8.21 years; modified Hoehn-Yahr [mH-Y] stage, 3.0±1.0; disease duration, 7...
2017: PloS One
https://www.readbyqxmd.com/read/29121334/pharmacotherapy-of-apnea-by-cannabimimetic-enhancement-the-pace-clinical-trial-effects-of-dronabinol-in-obstructive-sleep-apnea
#5
David W Carley, Bharati Prasad, Kathryn J Reid, Roneil Malkani, Hryar Attarian, Sabra M Abbott, Boris Vern, Hui Xie, Chengbo Yuan, Phyllis Zee
Study Objectives: There remains an important and unmet need for fully effective and acceptable treatments in obstructive sleep apnea (OSA). At present, there are no approved drug treatments. Dronabinol has shown promise for OSA pharmacotherapy in a small dose-escalation pilot study. Here, we present initial findings of the Phase II PACE (Pharmacotherapy of Apnea by Cannabimimetic Enhancement) trial, a fully-blinded parallel groups, placebo-controlled randomized trial of dronabinol in patients with moderate or severe OSA...
November 7, 2017: Sleep
https://www.readbyqxmd.com/read/29117882/excessive-daytime-sleepiness-in-acute-ischemic-stroke-association-with-restless-legs-syndrome-diabetes-mellitus-obesity-and-sleep-disordered-breathing
#6
Pavel Šiarnik, Katarína Klobučníková, Pavol Šurda, Matúš Putala, Stanislav Šutovský, Branislav Kollár, Peter Turčáni
STUDY OBJECTIVES: Sleep disorders are frequent in stroke patients. The prevalence of sleep-disordered breathing (SDB), excessive daytime sleepiness (EDS), and restless legs syndrome (RLS) among stroke survivors is up to 91%, 72%, and 15%, respectively. Although the relationship between EDS and SDB is well described, there are insufficient data regarding the association of EDS with RLS. The aim of this study was to explore the association between EDS, SDB, and RLS in acute ischemic stroke...
November 1, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29116571/quality-of-life-in-adult-patients-with-limb-girdle-muscular-dystrophies
#7
Marina Peric, Stojan Peric, Jelena Stevanovic, Sara Milovanovic, Ivana Basta, Ana Nikolic, Aleksandra Kacar, Vidosava Rakocevic-Stojanovic
Although limb-girdle muscular dystrophies (LGMD) can cause permanent disability, to date there are no studies that examined quality of life (QoL) in these patients. Our aim was to evaluate QoL in patients with LGMD, and to identify the most significant predictors of QoL. The study comprised 46 patients with diagnosis of limb-girdle muscular weakness. QoL in patients was evaluated using two scales-SF-36 questionnaire and the Individualized Neuromuscular Quality of Life questionnaire (INQoL). Following scales were also applied: Epworth Sleepiness Scale (ESS), Hamilton Scale for Depression (HamD), and Krupp's Fatigue Severity Scale (FSS)...
November 7, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29114733/sodium-oxybate-for-excessive-daytime-sleepiness-and-sleep-disturbance-in-parkinson-disease-a-randomized-clinical-trial
#8
Fabian Büchele, Marc Hackius, Sebastian R Schreglmann, Wolfgang Omlor, Esther Werth, Angelina Maric, Lukas L Imbach, Stefan Hägele-Link, Daniel Waldvogel, Christian R Baumann
Importance: Sleep-wake disorders are a common and debilitating nonmotor manifestation of Parkinson disease (PD), but treatment options are scarce. Objective: To determine whether nocturnal administration of sodium oxybate, a first-line treatment in narcolepsy, is effective and safe for excessive daytime sleepiness (EDS) and disturbed nighttime sleep in patients with PD. Design, Setting, and Participants: Randomized, double-blind, placebo-controlled, crossover phase 2a study carried out between January 9, 2015, and February 24, 2017...
November 6, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29108349/excessive-daytime-sleepiness-and-metabolic-syndrome-in-men-with-obstructive-sleep-apnea-a-large-cross-sectional-study
#9
Yiqun Fu, Huajun Xu, Yunyan Xia, Yingjun Qian, Xinyi Li, Jianyin Zou, Yuyu Wang, Lili Meng, Xulan Tang, Huaming Zhu, Huiqun Zhou, Kaiming Su, Dongzhen Yu, Hongliang Yi, Jian Guan, Shankai Yin
Purpose: Excessive daytime sleepiness is a common symptom in obstructive sleep apnea (OSA). Previous studies have showed that excessive daytime sleepiness is associated with some individual components of metabolic syndrome. We performed a large cross-sectional study to explore the relationship between excessive daytime sleepiness and metabolic syndrome in male OSA patients. Methods: A total of 2241 suspected male OSA patients were consecutively recruited from 2007 to 2013...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29106778/evolution-of-soft-palate-surgery-techniques-for-obstructive-sleep-apnea-patients-a-comparative-study-for-single-level-palatal-surgeries
#10
Mohamed S Rashwan, Filippo Montevecchi, Giovanni Cammaroto, Mohamed Badr El Deen, Nagi Iskander, Diaa El Hennawi, Mohammed El Tabbakh, Giuseppe Meccariello, Riccardo Gobbi, Francesco Stomeo, Claudio Vicini
OBJECTIVES: to compare the results of tissue preservation techniques of soft palate surgeries including expansion sphincter pharyngoplasty (ESP) and barbed reposition pharyngoplasty (BRP) for patients suffering from obstructive sleep apnea (OSA) with the traditional uvulopalatopharyngoplasty (UPPP). DESIGN: interventional comparative study. SETTING: Morgagni- Pierantoni Hospital. PARTICIPANTS: seventy five patients were included in the study, divided into three groups with 25 patients per group: UPPP, ESP or BRP...
November 6, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29105874/nocturnal-nasal-obstruction-is-frequent-and-reduces-sleep-quality-in-patients-with-obstructive-sleep-apnea
#11
Maria Värendh, Morgan Andersson, Erla Bjørnsdottir, Harald Hrubos-Strøm, Arne Johannisson, Erna S Arnardottir, Thorarinn Gislason, Sigurdur Juliusson
The prevalence and consequences of nasal obstruction in untreated obstructive sleep apnea patients are not known. The study objectives were to investigate the frequency of subjective and objective nasal obstruction in untreated sleep apnea patients and the associations with sleep and quality of life. Patients in the Icelandic Sleep Apnea Cohort were subjected to a type 3 sleep study, answered questionnaires and had their nasal dimensions measured by acoustic rhinometry. In total, 810 patients participated (including 153 females), aged 54...
November 6, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/29105336/sleep-quality-and-quality-of-life-in-patients-with-moderate-to-very-severe-copd
#12
Buket Akinci, Gökşen Kuran Aslan, Esen Kiyan
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is highly associated with Obstructive Sleep Apnea (OSA). Poor sleep quality found related with decreased quality of life in COPD patients but no study assessed this relationship on the basis of nocturnal sleep parameters. OBJECTIVES: The aim of this study is to explore relationships between sleep quality, daytime sleepiness, and quality of life in moderate to very severe COPD patients with and without sleep apnea assessed objectively and compare sleep quality, quality of life and daytime sleepiness in COPD patients with and without sleep apnea...
November 4, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29101760/sexual-dysfunction-in-premenopausal-women-with-obstructive-sleep-apnea
#13
Zahide Yilmaz, Pinar Bekdik Sirinocak, Bekir Voyvoda, Levent Ozcan
PURPOSE: Sexual functions in the males with obstructive sleep apnea syndrome (OSAS) have been well investigated in the literature; however sexual functions in the premenopausal women with OSAS have been studied to a lesser extent. MATERIALS AND METHODS: The study included 22 premenopausal women diagnosed as OSAS by the polysomnographic (PSG) evaluation. The control group included 13 premenopausal women suspected of sleep-relatedrespiratory disorder, but whose PSG tests were determined to be normal...
November 4, 2017: Urology Journal
https://www.readbyqxmd.com/read/29098917/sleep-pattern-and-decision-making-in-physicians-from-mobile-emergency-care-service-with-12-hour-work-schedules
#14
Eleni de Araújo Sales Castro, Katie Moraes de Almondes
INTRODUCTION: Shift work schedules are biological standpoint worse because compel the body to anticipate periods of wakefulness and sleep and thus eventually cause a disruption of biological rhythms. OBJECTIVE: To evaluate the sleep pattern and decision making in physicians working in mobile units of emergency attention undergoing Day Shift and Rotating Shift. METHODS: The study included 26 physicians. The instruments utilized were a sociodemographic questionnaire, the Pittsburgh Sleep Quality Index (PSQI), the Sleep Habits Questionnaire, the Epworth Sleepiness Scale and Chronotype Identification Questionnaire of Horne-Ostberg, the Iowa Gambling Task (IGT) and hypothetical scenarios of decision-making created according to the Policy-Capturing Technique...
November 3, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/29091777/assessment-of-sleep-quality-in-bipolar-euthymic-patients
#15
Necla Keskin, Lut Tamam, Nurgul Ozpoyraz
OBJECTIVE: Sleep quality is affected in bipolar disorder even in euthymic episodes. The aim of this study was to assess sleep quality in bipolar euthymic patients, determine related clinical characteristics and evaluate its effects on functionality. METHODS: A total of 122 outpatients were included. Scales were used to confirm that patients were euthymic. Mini Mental Test was performed to exclude patients with a diagnosis of dementia. A data form for socio-demographic features and clinical characteristics of bipolar disorder have been completed...
September 30, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29084403/high-frequency-of-sleep-disorders-in-parkinson-s-disease-and-its-relationship-with-quality-of-life
#16
Manoel Alves Sobreira-Neto, Márcio Alexandre Pena-Pereira, Emmanuelle Silva Tavares Sobreira, Marcos Hortes Nisihara Chagas, Regina Maria França Fernandes, Vitor Tumas, Alan Luiz Eckeli
OBJECTIVES: To determine the frequency of major sleep disorders in patients with Parkinson's disease (PD), diagnosed according to the third international classification of sleep disorders, and assess the relationship of those disorders with the quality of life. METHODS: A cross-sectional study was performed involving 88 consecutive patients with PD from outpatient clinic. Participants were subjected to clinical interviews, assessment using standardized scales (Epworth Sleepiness Scale, PD Questionnaire, Pittsburgh sleep quality index (PSQI) and, for individuals with a diagnosis of RLS/WED, International RLS/WED grading scale), and video-polysomnography...
October 30, 2017: European Neurology
https://www.readbyqxmd.com/read/29082906/sleep-quality-among-nurses-in-a-tertiary-hospital-in-north-west-nigeria
#17
Ibrahim Aliyu, Zainab F Ibrahim, Lawal O Teslim, Helen Okhiwu, Igoche David Peter, Godpower Chinedu Michael
BACKGROUND: Sleep is a necessity; it is nourishing, refreshing and healing. The nursing profession is associated with busy and difficult work schedules, especially the running of shifts which has been associated with cardiovascular and metabolic complications. There is a dearth of local data on sleep disorders, especially among nurses. In this study, we evaluated the quality of sleep and the tendency of daytime sleepiness among nurses. SUBJECTS AND METHODS: This study was cross-sectional in nature involving 100 nurses working with Federal Medical Centre Birnin Kebbi, Kebbi State; the study was carried out between October 2016 and February 2017...
July 2017: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29080065/effects-of-respiratory-muscle-training-rmt-in-patients-with-mild-to-moderate-obstructive-sleep-apnea-osa
#18
Simon Dominik Herkenrath, Marcel Treml, Christina Priegnitz, Wolfgang Galetke, Winfried J Randerath
PURPOSE: Different forms of training focusing on the muscles of the upper airways showed limited effects on obstructive sleep apnea (OSA) and/or snoring. We investigated the effect of generalized respiratory muscle training (RMT) in lean patients with mild to moderate OSA. METHODS: Nine male subjects (52.0 ± 10.8 years, BMI 29.1 ± 2.1 kg/m(2)) with obstructive sleep apnea (apnea-hypopnea index (AHI) 9-29) participated in an open, single-arm pilot study. After a 1-week build-up phase, patients underwent 4 weeks of normocapnic hyperpnea RMT five times a week for 30 min each...
October 28, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29079603/combination-of-obstructive-sleep-apnoea-and-insomnia-treated-by-continuous-positive-airway-pressure-with-the-sensawake-pressure-relief-technology-to-assist-sleep-a-randomised-cross-over-trial-protocol
#19
Jean Louis Pepin, Frédéric Gagnadoux, Alison Foote, Rachel Vicars, Bhavi Ogra, Véronique Viot-Blanc, Meriem Benmerad, Marie-Pia D'Ortho, Renaud Tamisier
INTRODUCTION: Obstructive sleep apnoea (OSA) is a common sleep breathing disorder affecting up to 17% of the middle-aged population. Continuous positive airway pressure (CPAP) is the primary treatment for patients with OSA, but acceptance and adherence to therapy is suboptimal in specific subgroups particularly those with insomnia or poor sleep quality (40%-80% of patients with OSA). Pressure intolerance, particularly during periods of wakefulness, inhibiting sleep onset or return to sleep, is one reason for poor CPAP adherence...
October 27, 2017: BMJ Open
https://www.readbyqxmd.com/read/29075566/sleep-disturbances-in-taiwanese-patients-with-parkinson-s-disease
#20
Yi-Ying Lin, Rou-Shayn Chen, Chin-Song Lu, Ying-Zu Huang, Yi-Hsin Weng, Tu-Hsueh Yeh, Wey-Yil Lin, June Hung
INTRODUCTION: Sleep disturbance is a common nonmotor symptom of Parkinson's disease (PD) and strongly affects patients' quality of life. The relationship between excessive daytime sleepiness (EDS) and nighttime problems remains uncertain. Arguments persist regarding the risk factors for sleep disturbance among patients with PD. Furthermore, the prevalence of EDS appears to be lower in Asian countries. Herein, we conducted the study to describe the characteristics of sleep problems in a sample of Taiwanese PD patients and delineate the difference with reported sleep disturbances in Caucasian PD patients from the literature...
October 2017: Brain and Behavior
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