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https://www.readbyqxmd.com/read/28545163/coccygeal-body-revisited-an-immunohistochemical-study-using-donated-elderly-cadavers
#1
Zhe Wu Jin, Kwang Ho Cho, Hyung Suk Jang, Gen Murakami, Jose Francisco Rodríguez-Vázquez, Masahito Yamamoto, Shin-Ichi Abe
To describe the normal anatomy and histology of the adult coccygeal body (CB) and to discuss about the origin and function. Using immunohistochemistry, we examined 29 CBs found in 32 elderly donated cadavers without macroscopic pathology in the pelvis. The CB was usually located in or near the anococcygeal ligaments. It was almost always composed of multiple masses or nodules of round glomus cells (smooth muscle actin, or SMA++). However, the CB sometimes contained abundant dilated veins with scattered glomus cells...
May 25, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28545097/an-integrated-risk-predictor-for-pulmonary-nodules
#2
Paul Kearney, Stephen W Hunsucker, Xiao-Jun Li, Alex Porter, Steven Springmeyer, Peter Mazzone
It is estimated that over 1.5 million lung nodules are detected annually in the United States. Most of these are benign but frequently undergo invasive and costly procedures to rule out malignancy. A risk predictor that can accurately differentiate benign and malignant lung nodules could be used to more efficiently route benign lung nodules to non-invasive observation by CT surveillance and route malignant lung nodules to invasive procedures. The majority of risk predictors developed to date are based exclusively on clinical risk factors, imaging technology or molecular markers...
2017: PloS One
https://www.readbyqxmd.com/read/28544819/dual-malignancy-in-a-thyroid-papillary-thyroid-carcinoma-and-small-lymphocytic-lymphoma-a-report-of-a-case-with-a-cyto-histologic-correlation
#3
Omar I Ahmed, Ziyan T Salih
Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy. Simultaneous involvement of the thyroid gland by multiple malignancies, is a rare occurrence. Similarly, primary thyroid lymphomas are also rare. We are reporting a rare case of a dual thyroid malignancy; PTC with secondary thyroid involvement by chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), diagnosed on cytology and confirmed with flow cytometry, histology and immunohistochemistry. Imaging showed two hypermetabolic nodules, one in left parotid gland, and the other in the thyroid isthmus...
May 22, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28544601/the-impact-of-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-on-the-performance-of-the-afirma-gene-expression-classifier
#4
Jen-Fan Hang, William H Westra, David S Cooper, Syed Z Ali
BACKGROUND: A recent revision in thyroid tumor nomenclature has resulted in a change from a malignant diagnosis (noninvasive follicular variant of papillary thyroid carcinoma) to one that is nonmalignant (noninvasive follicular thyroid neoplasm with papillary-like nuclear features [NIFTP]). The objective of the current study was to evaluate the impact of this change on the performance of the Afirma gene expression classifier (GEC). METHODS: The authors retrospectively analyzed consecutive thyroid fine-needle aspiration specimens with indeterminate diagnoses on which GEC was performed...
May 24, 2017: Cancer
https://www.readbyqxmd.com/read/28544587/drop-out-rate-from-the-liver-transplant-waiting-list-due-to-hcc-progression-in-hcv-infected-patients-treated-with-direct-acting-antivirals
#5
Alberto Zanetto, Sarah Shalaby, Alessandro Vitale, Claudia Mescoli, Alberto Ferrarese, Martina Gambato, Enrica Franceschet, Giacomo Germani, Marco Senzolo, Antonietta Romano, Paolo Angeli, Massimo Rugge, Fabio Farinati, Daniel M Forton, Umberto Cillo, Patrizia Burra, Francesco Paolo Russo
BACKGROUND & AIM: concerns about an increased hepatocellular carcinoma (HCC) recurrence rate following directly acting antiviral (DAA) therapy in cirrhotic patients with a prior complete oncological response have been raised. Data regarding the impact of HCV-treatment with DAAs on waiting list drop-out rates in patients with active HCC and HCV-related cirrhosis awaiting liver transplantation (LT) are lacking. MATERIALS AND METHODS: HCV-HCC patients listed for LT between January 2015 and May 2016 at Padua Liver Transplant Centre were considered eligible for the study...
May 22, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28544576/atypical-adenoma-of-the-thyroid-diagnosed-as-anaplastic-cancer-by-cytopathology
#6
Hiromitsu Hatakeyama, Kimiko Hoshino, Kenji Mizoguchi, Takayoshi Suzuki, Kanako C Hatanaka, Yukie Yamaya, Satoshi Kano, Takatsugu Mizumachi, Akihiro Homma
Atypical adenoma of the thyroid is a rare form of tumor, and its accurate diagnosis prior to surgical resection is difficult as the histological and pathological morphologies are very similar to those of anaplastic thyroid carcinoma (ATC), and its anaplastic transformation remains to be elucidated. We reported a case of a 75-year-old female with a thyroid isthmus nodule diagnosed repeatedly by FNAC as anaplastic carcinoma. Both the first and second FNAC specimen slides showed a large number of scattered or aggregated atypical cells consisting of large, pleomorphic nuclei with irregular membranes, chromatin clumps and prominent nucleoli...
May 22, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28544414/effective-low-cost-recovery-of-toxic-arsenate-anions-from-water-using-hollow-sphere-trapper-geodes
#7
Sherif A El-Safty, Mohamed A Shenashen, Naeem Akhtar, Mahmoud M Selim, Wafaa M Morsy, Hitoshi Yamaguchi, Satoshi Kawada, Abdulaziz A Alhamid, Naoki Ohashi, Izumi Ichinose, Ahmed Alamoudi
Because of the devastating impacts of arsenic to terrestrial and aquatic organisms, recovery, removal, disposal and management of arsenic-contaminated water has a considerable challenge and become an urgent necessity in the field of water treatment. This study reports control fabrication of low-cost adsorbents based on microscopic NiO hollow sphere geode-shelled a 100 nm of poly-CN nano-sphere particles-like nodules of poly-carbon nitride that intrinsically stacked and wrapped around the hollow nest spheres to form 500-700 nm shell...
May 22, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28544062/clinical-outcomes-of-stereotactic-body-radiotherapy-for-elderly-patients-with-hepatocellular-carcinoma
#8
Yuji Teraoka, Tomoki Kimura, Hiroshi Aikata, Kana Daijo, Mitsutaka Osawa, Fumi Honda, Yuki Nakamura, Kei Morio, Reona Morio, Masahiro Hatooka, Tomoki Kobayashi, Takashi Nakahara, Eisuke Murakami, Yuko Nagaoki, Tomokazu Kawaoka, Masataka Tsuge, Akira Hiramatsu, Michio Imamura, Yoshiiku Kawakami, Yasushi Nagata, Kazuaki Chayama
BACKGROUND/AIM: To evaluate the safety and efficacy of stereotactic body radiotherapy (SBRT) for the treatment of hepatocellular carcinoma (HCC) in elderly patients. METHODS: From 2008 to 2015, 117 patients with HCC (≦3 nodules, ≦30 mm in diameter, Child-Pugh score ≦7, no vascular or extracellular metastasis) were treated with SBRT at our hospital. We evaluated overall survival (OS), disease-free survival (DFS), local control, and adverse events. Patients were stratified according to age 75 years and older (elderly group, n = 54) and age younger than 75 years (young group, n = 63)...
May 20, 2017: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/28543860/a-unique-case-of-bilateral-ovarian-splenosis-and-review-of-the-literature
#9
Maria Giulia Disanto, Francesca Mercalli, Andrea Palicelli, Alberto Arnulfo, Renzo Boldorini
Splenosis is an acquired anomaly related to heterotopic auto-transplantation of splenic tissue following abdominal trauma or splenectomy. We report the first definitive bilateral ovarian case in a 65-year-old woman who underwent splenectomy following a motor vehicle accident 44 years prior to presentation. We review the literature and discuss the main differential diagnoses. Gross examination revealed a 1-cm well-circumscribed dark nodule on the surface of each ovary. Paraffin-embedded, formalin-fixed blocks were sectioned and stained with hematoxylin-eosin and immunostains (CK5/6, Calretinin, WT1, Vimentin)...
May 25, 2017: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/28543852/cutaneous-granular-cell-tumors-in-children-case-series-and-review-of-the-literature
#10
Oluwatobi Olayiwola, Kristen Hook, Daniel Miller, Sheilagh Maguiness
Granular cell tumors (GCTs) are uncommon benign neoplasms thought to originate from Schwann cells. They most commonly present in adults as papules or nodules on mucosal sites. The clinical spectrum of GCT in children is not well delineated, although mucosal and cutaneous presentations have been reported. We present three children with cutaneous GCTs and review the literature in an attempt to further characterize this rare pediatric neoplasm.
May 25, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28542660/-trichomycosis-trichobacteriosis-capitis-in-an-infant-microbiological-dermoscopic-and-ultrastructural-features
#11
Alexandro Bonifaz, Ixchel Ramírez-Ricarte, Alejandra Rodríguez-Leviz, Marco A Hernández, Carlos Mena, Adriana Valencia
Trichomycosis is a superficial infection caused by Corynebacterium flavescens, which regularly affects axillary, and to a a lesser extent, pubic, scrotal and intergluteal, and exceptionally, head hairs or trichomycosis capitis (TC). This condition is characterised by the formation of bacterial nodules. Clinically, it can be confused with white piedra or pediculosis. The diagnosis is made by microscopic and dermoscopic observation and confirmed by culture. OBJECTIVE: To present a case of TC in an infant and illustrate the microscopic, dermoscopic, and ultrastructural characteristics...
April 2017: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/28542442/pedogenetic-processes-in-anthrosols-with-pretic-horizon-amazonian-dark-earth-in-central-amazon-brazil
#12
Rodrigo S Macedo, Wenceslau G Teixeira, Marcelo M Corrêa, Gilvan C Martins, Pablo Vidal-Torrado
Anthrosols known as Amazonian Dark Earth (ADE) have borne witness to the intensification of sedentary patterns and the demographic increase in Central Amazon. As a result, a recurring pattern has been observed of mounds with ADE arising from domestic activities and the disposal of waste. The objective of this research was to demonstrate the relationship of these anthropic activities with pedogenetic formation processes of ADE in the municipality of Iranduba, Brazil. Disturbed and undisturbed soil samples were taken from two areas of ADE (pretic horizon) and from a non-anthropic pedon...
2017: PloS One
https://www.readbyqxmd.com/read/28541751/a-novel-experimental-model-of-colorectal-endometriosis
#13
Anastasia Prodromidou, Vasilios Pergialiotis, Kitty Pavlakis, Laskarina Maria Korou, Maximos Frountzas, Dimitrios Dimitroulis, Georgios Vaos, Despina N Perrea
PURPOSE: Endometriosis is a disease that affects 6-10% of the female population, mainly women of reproductive age, and causes a variety of cyclic symptoms. Deep infiltrating endometriosis and in particular bowel involvement presents a challenge for modern surgery. To date, there are no experimental animal models in this field, demonstrating experimental induction of endometriosis directly attached to surface of the colon imitating human colorectal endometriosis; hence, the implementation of novel pharmaceutical and surgical strategies for the management of colorectal endometriosis is mainly limited to clinical studies...
May 25, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28541140/chest-ultrasound-findings-in-pulmonary-tuberculosis
#14
Paolo Agostinis, Roberto Copetti, Laura Lapini, Geraldo Badona Monteiro, Augusto N'Deque, Aldo Baritussio
In resource-limited countries, the diagnosis of pulmonary tuberculosis (TB) is based on clinical findings, chest radiography and the demonstration of acid-fast bacilli in sputum. Few data are available on the use of ultrasound (US) to diagnose pulmonary TB. Chest US was performed in patients with lung TB from a rural African setting, to look for signs of the disease and to clarify the role US may have in the diagnosis of pulmonary TB. Sixty adult patients diagnosed with lung TB underwent chest US. All patients had abnormal findings...
January 1, 2017: Tropical Doctor
https://www.readbyqxmd.com/read/28540905/tuberous-sclerosis-complex-bourneville-pringle-disease-in-a-25-year-old-female-with-bilateral-renal-angiomyolipoma-and-secondary-hypertension
#15
Sahar El Aoud, Faten Frikha, Mouna Snoussi, Raida Ben Salah, Zouhir Bahloul
Tuberous sclerosis or tuberous sclerosis complex (TSC) is an autosomal dominant inherited neurocutaneous disorder that variably affects the brain, skin, kidneys, heart, and other organs. It is characterized by skin and renal lesions in addition to central and peripheral nervous system tumors, with neurological and psychiatric findings. We report such a rare case of tuberous sclerosis in a 25-year-old female who presented with abdominal pain and hypertension. Physical examination showed dermatological signs that included hypopigmented maculae, shagreen plaque, angiofibromas on the centrofacial areas, periungual fibromas on toes, and molluscum pendulum around the neck...
May 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28540836/vocal-cord-paresis-following-single-session-high-intensity-focused-ablation-hifu-treatment-of-benign-thyroid-nodules-incidence-and-risk-factors
#16
Brian Hh Lang, Yu-Cho Woo, Keith Wan-Hang Chiu
BACKGROUND: Vocal cord paresis (VCP) may occur following high intensity focused ultrasound (HIFU) of thyroid nodules. We hypothesized its occurrence relates to the distance of the focus point (FP) of the HIFU beams from the recurrent laryngeal nerve (RLN) and the thermal power that this point received. Their relationships were examined. METHODS: One hundred and three patients who underwent HIFU for symptomatic benign thyroid nodule from October 2015 to March 2017 were analyzed...
May 24, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28540810/minimally-invasive-local-ablative-therapies-in-combination-with-radioiodine-therapy-in-benign-thyroid-disease-preparation-feasibility-and-efficiency-preliminary-results
#17
Alexander Mader, Oscar Maximilian Mader, Daniel Gröner, Yücel Korkusuz, Shadi Ahmad, Frank Grünwald, W Tilman Kranert, Christian Happel
PURPOSE: Initial studies of combinations of radioiodine therapy (RIT) and local ablative procedures for the treatment of thyroid nodules have shown promising results. The goal of this study was to evaluate the effectiveness of RIT combined with radiofrequency ablation (RFA) in patients with goitres and to determine which ablative procedure is the most suitable for a combined therapy. METHODS: Thirty patients with goitres were divided into two subgroups. A test group of 15 patients received combined therapy (RIT + RFA) and a control group of 15 patients received RIT mono therapy...
May 5, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28540804/high-intensity-focused-ablation-hifu-of-single-benign-thyroid-nodule-rarely-alters-underlying-thyroid-function
#18
Brian H H Lang, Yu-Cho Woo, Keith Wan-Hang Chiu
BACKGROUND: High intensity focused ultrasound (HIFU) is a promising ablation technique for benign thyroid nodules. However, its effect on underlying thyroid function remains unknown. We aimed to evaluate the 6 months changes in serum thyroid stimulating hormone (TSH) and free thyroxine (FT4) after HIFU treatment. METHODS: Eighty-three consecutive patients who underwent single HIFU ablation for symptomatic benign thyroid nodule were analysed. Eligible patients had serum TSH and FT4 checked before treatment (baseline), 1 week, 3 and 6 months following HIFU treatment...
April 24, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28540795/radiofrequency-ablation-of-benign-thyroid-nodules-depicting-early-sign-of-regrowth-by-calculating-vital-volume
#19
Jung Suk Sim, Jung Hwan Baek, Joongyub Lee, Woojin Cho, Sung Il Jung
OBJECTIVE: We evaluated long-term follow-up results of radiofrequency ablation of benign thyroid nodules to analyse the role of marginal vital tissue on nodule regrowth. MATERIALS AND METHODS: We reviewed the medical records of 54 patients who underwent radiofrequency ablation between June 2008 and November 2013 with pressure symptoms, and/or cosmetic problems. All patients were followed up at least 12 months on three occasions. To evaluate an early sign of regrowth, three types of nodule volumes (total volume, ablated volume and vital volume) were measured and calculated using ultrasonography...
April 10, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28540786/benign-thyroid-nodules-treatment-using-percutaneous-laser-ablation-pla-and-radiofrequency-ablation-rfa
#20
Hye Sun Park, Jung Hwan Back, Dong Gyu Na
No abstract text is available yet for this article.
March 29, 2017: International Journal of Hyperthermia
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