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https://www.readbyqxmd.com/read/29771933/the-colours-and-contours-of-compassion-a-systematic-review-of-the-perspectives-of-compassion-among-ethnically-diverse-patients-and-healthcare-providers
#1
Pavneet Singh, Kathryn King-Shier, Shane Sinclair
OBJECTIVE: To identify and describe the perspectives, experiences, importance, and impact of compassionate care among ethnically diverse population groups. METHODS: A systematic search of peer-reviewed research focused on compassionate care in ethnically diverse populations published between 1946 and 2017 was conducted. RESULTS: A total of 2296 abstracts were retrieved, out of which 23 articles met the inclusion criteria. Synthesis of the literature identified the perspectives, facilitators and barriers of compassion in healthcare within ethnic groups...
2018: PloS One
https://www.readbyqxmd.com/read/29752650/traumatic-knee-injury-correlation-of-radiographic-effusion-size-with-the-presence-of-internal-derangement-on-magnetic-resonance-imaging
#2
Nathan D Cecava, Shane Dieckman, Kevin P Banks, Liem T Mansfield
PURPOSE: Traumatic knee injury is a common clinical presentation. However, knee internal derangement often goes undiagnosed on physical exam. The authors hypothesize that patients with suprapatellar joint effusion greater than 10 mm anteroposterior diameter on lateral radiograph have a high likelihood of knee internal derangement on magnetic resonance imaging. MATERIALS AND METHODS: A retrospective review of knee radiographs and magnetic resonance imaging in 198 patients age 18-40 years with acute knee injury was performed...
May 8, 2018: Emergency Radiology
https://www.readbyqxmd.com/read/29741725/ventilatory-control-sensitivity-in-patients-with-obstructive-sleep-apnea-is-sleep-stage-dependent
#3
Shane A Landry, Christopher Andara, Philip I Terrill, Simon A Joosten, Paul Leong, Dwayne L Mann, Scott A Sands, Garun S Hamilton, Bradley A Edwards
Study Objectives: The severity of obstructive sleep apnea (OSA) is known to vary according to sleep stage; however, the pathophysiology responsible for this robust observation is incompletely understood. The objective of the present work was to examine how ventilatory control system sensitivity (i.e. loop gain) varies during sleep in patients with OSA. Methods: Loop gain was estimated using signals collected from standard diagnostic polysomnographic recordings performed in 44 patients with OSA...
May 1, 2018: Sleep
https://www.readbyqxmd.com/read/29710124/automated-and-clinical-breast-imaging-reporting-and-data-system-density-measures-predict-risk-of-screen-detected-and-interval-cancers
#4
Karla Kerlikowske, Christopher G Scott, Amir P Mahmoudzadeh, Lin Ma, Stacey Winham, Matthew R Jensen, Fang Fang Wu, Serghei Malkov, V Shane Pankratz, Steven R Cummings, John A Shepherd, Kathleen R Brandt, Diana L Miglioretti, Celine M Vachon
Background: In 30 states, women who have had screening mammography are informed of their breast density on the basis of Breast Imaging Reporting and Data System (BI-RADS) density categories estimated subjectively by radiologists. Variation in these clinical categories across and within radiologists has led to discussion about whether automated BI-RADS density should be reported instead. Objective: To determine whether breast cancer risk and detection are similar for automated and clinical BI-RADS density measures...
May 1, 2018: Annals of Internal Medicine
https://www.readbyqxmd.com/read/29695327/high-sensitivity-troponin-the-sisyphean-pursuit-of-zero-percent-miss-rate-for-acute-coronary-syndrome-in-the-emergency-department
#5
REVIEW
Shane M Summers, Brit Long, Michael D April, Alex Koyfman, Curtis J Hunter
BACKGROUND: The United States Food and Drug Administration recently approved a high sensitivity troponin (hsTn) assay for use. Recent literature has investigated the diagnostic accuracy of hsTn for acute coronary syndrome (ACS) in the emergency department (ED) and its use in accelerated diagnostic protocols. OBJECTIVE: This article evaluates the existing literature and discusses incorporation of hsTn testing into ED clinical practice based on best available evidence...
April 3, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29687474/field-validation-of-pocis-for-monitoring-at-underwater-munitions-sites
#6
Gunther Rosen, Guilherme R Lotufo, Robert D George, Bill Wild, Lauren K Rabalais, Shane Morrison, Jason B Belden
The present study evaluated Polar Organic Chemical Integrative Samplers (POCIS) for quantification of conventional munitions constituents (MC), including trinitrotoluene (TNT), aminodinitrotoluenes, diaminonitrotoluenes, dinitrotoluene, and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) in a field setting. POCIS were deployed at varying distances from the commonly used explosive formulation Composition B (39.5% TNT, 59.5% RDX, 1% wax) in an embayment of Santa Rosa Sound (Florida, USA). Time-weighted averaged (TWA) water concentrations from a 13-day deployment ranged from 9-103 ng/L for TNT and RDX approximately 0...
April 24, 2018: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/29594872/calcium-calmodulin-stimulated-adenylyl-cyclases-1-and-8-regulate-reward-related-brain-activity-and-ethanol-consumption
#7
Kelly E Bosse, Farhad Ghoddoussi, Ajay T Eapen, Jennifer L Charlton, Laura L Susick, Kirt Desai, Bruce A Berkowitz, Shane A Perrine, Alana C Conti
Evidence suggests a predictive link between elevated basal activity within reward-related networks (e.g., cortico-basal ganglia-thalamic networks) and vulnerability for alcoholism. Both calcium channel function and cyclic adenosine monophosphate (cAMP)/protein kinase A-mediated signaling are critical modulators of reward neurocircuitry and reward-related behaviors. Calcium/calmodulin-stimulated adenylyl cyclases (AC) 1 and 8 are sensitive to activity-dependent increases in intracellular calcium and catalyze cAMP production...
March 28, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29570577/lower-extremity-horizontal-single-leg-hop-distance-but-not-vertical-power-predicts-lower-extremity-injury-in-female-collegiate-dancers
#8
Jatin P Ambegaonkar, Catherine Schock, Shane V Caswell, Nelson Cortes, Jena Hansen-Honeycutt, Matthew A Wyon
Dancers often perform powerful and explosive movements that require adequate lower extremity(LE) activity in horizontal and vertical directions. We examined if these measures were interrelated and whether they predicted LE injury status in dancers using binary logistic regressions and Receiver Operator Characteristic(ROC) curve analyses. Forty-three collegiate female dancers(18+0.7yrs; 162.6+5.9cm; 59.4+7.1kg) performed Single Leg Hop(SLH,m), and Vertical Jump(VJ,cm) tests. SLH and VJ distances were used to calculate SLH_norm (as a % of body height) and Vertical Power(vPower,watts)...
March 22, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29566195/lifestyle-metabolite-and-genetic-determinants-of-formate-concentrations-in-a-cross-sectional-study-in-young-healthy-adults
#9
John T Brosnan, James L Mills, Per M Ueland, Barry Shane, Ruzong Fan, Chi-Yang Chiu, Faith Pangilinan, Lawrence C Brody, Margaret E Brosnan, Theerawat Pongnopparat, Anne M Molloy
Background: Formate is an important metabolite that serves as a donor of one-carbon groups to the intracellular tetrahydrofolate pool. However, little is known of its circulating concentrations or of their determinants. Objective: This study aimed to define formate concentrations and their determinants in a healthy young population. Design: Serum formate was measured in 1701 participants from the Trinity Student Study. The participants were men and women, aged 18 to 28 y, enrolled at Trinity College, Dublin...
March 1, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29544197/lethal-and-sublethal-toxicity-of-neonicotinoid-and-butenolide-insecticides-to-the-mayfly-hexagenia-spp
#10
Adrienne J Bartlett, Amanda M Hedges, Kyna D Intini, Lisa R Brown, France J Maisonneuve, Stacey A Robinson, Patricia L Gillis, Shane R de Solla
Neonicotinoid insecticides are environmentally persistent and highly water-soluble, and thus are prone to leaching into surface waters where they may negatively affect non-target aquatic insects. Most of the research to date has focused on imidacloprid, and few data are available regarding the effects of other neonicotinoids or their proposed replacements (butenolide insecticides). The objective of this study was to assess the toxicity of six neonicotinoids (imidacloprid, thiamethoxam, acetamiprid, clothianidin, thiacloprid, and dinotefuran) and one butenolide (flupyradifurone) to Hexagenia spp...
July 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29533689/effects-of-arthroscopy-for-femoroacetabular-impingement-syndrome-on-quality-of-life-and-economic-outcomes
#11
Richard C Mather, Shane J Nho, Andrew Federer, Berna Demiralp, Jennifer Nguyen, Asha Saavoss, Michael J Salata, Marc J Philippon, Asheesh Bedi, Christopher M Larson, J W Thomas Byrd, Lane Koenig
BACKGROUND: The diagnosis and treatment of femoroacetabular impingement (FAI) have increased steadily within the past decade, and research indicates clinically significant improvements after treatment of FAI with hip arthroscopy. PURPOSE: This study examined the societal and economic impact of hip arthroscopy by high-volume surgeons for patients with FAI syndrome aged <50 years with noncontroversial diagnosis and indications for surgery. STUDY DESIGN: Economic and decision analysis; Level of evidence, 2...
April 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29526682/the-prevalence-of-gestational-diabetes-mellitus-amongst-black-south-african-women-is-a-public-health-concern
#12
Shelley Macaulay, Martha Ngobeni, David B Dunger, Shane A Norris
AIMS: This study aimed to determine the prevalence of gestational diabetes mellitus (GDM) amongst black South African women, describe GDM-associated risk factors and clinical management, and evaluate the efficacy of the fasting plasma glucose reading in diagnosing GDM. METHODS: A cross-sectional screening study was performed. Pregnant women were recruited from the Chris Hani Baragwanath Academic Hospital in Johannesburg. A total of 1906 women underwent a two-hour 75 g oral glucose tolerance test at 24-28 weeks gestation...
May 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29524292/review-and-clinical-experience-exploring-evidence-clinical-efficacy-and-safety-regarding-nonsurgical-treatment-of-feminine-rejuvenation
#13
Michael Gold, Anneke Andriessen, Alexandros Bader, Red Alinsod, Elizabeth Shane French, Nathan Guerette, Yegor Kolodchenko, Michael Krychman, Susan Murrmann, Julene Samuels
INTRODUCTION: The use of energy-based devices for the treatment of vaginal laxity, orgasmic dysfunction, and stress incontinence, such as minimally ablative fractional laser and radiofrequency, is gaining momentum. This review aims to answer clinical questions on the application of energy-based devices for feminine genital rejuvenation. METHODS: The target group includes physicians involved in esthetic medicine and feminine genital rejuvenation. A literature review was conducted on technologies in use for feminine rejuvenation to explore their safety, efficacy, tolerability, patient satisfaction, and clinical usability...
March 10, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29513205/validation-of-the-brief-developmental-assessment-in-pre-school-children-with-heart-disease
#14
Katherine L Brown, Deborah A Ridout, Christina Pagel, Monica Lakhanpaul, Suzan Kakat, Victoria Banks, Rodney Franklin, Thomas Witter, Rhian Lakhani, Shane Tibby, David Anderson, Victor Tsang, Aparna U Hoskote, Jo Wray
Introduction The objective of this study was to prospectively validate the "Brief Developmental Assessment", which is a new early recognition tool for neurodevelopmental abnormalities in children with heart disease that was developed for use by cardiac teams. METHODS: This was a prospective validation study among a representative sample of 960 pre-school children with heart disease from three United Kingdom tertiary cardiac centres who were analysed grouped into five separate age bands...
April 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29469845/inverse-design-of-optical-elements-based-on-arrays-of-dielectric-spheres
#15
Alan Zhan, Taylor K Fryett, Shane Colburn, Arka Majumdar
Arrays of wavelength scale scatterers are a promising platform for designing optical elements with a compact footprint. The large number of degrees of freedom in this system allows for unique and plentiful functionalities. However, the many variables also create a complex design problem. While intuitive forward design methods work for simple optical elements, they often fail to produce complicated elements, especially those involving multiple elements. We present an inverse design methodology for large arrays of wavelength scale spheres based on both adjoint optimization or sensitivity analysis and generalized multi-sphere Mie theory as a solution to the design problem...
February 20, 2018: Applied Optics
https://www.readbyqxmd.com/read/29419543/evaluation-of-mitf-sox10-mart-1-and-r21-immunostaining-for-the-diagnosis-of-residual-melanoma-in-situ-on-chronically-sun-damaged-skin
#16
Euphemia W Mu, Nicola A Quatrano, Sarah E Yagerman, Desiree Ratner, Shane A Meehan
BACKGROUND: Melanocytic immunostains can assist in margin evaluation of melanoma in situ (MIS) excisions; however, their accuracy and reliability relative to hematoxylin & eosin (H&E) is yet to be determined. OBJECTIVE: The objective of this study was to evaluate the sensitivity, specificity, and concordance of 4 melanocyte-specific immunostains for diagnosing MIS occurring on chronically sun-damaged skin. MATERIALS AND METHODS: Serial permanent sections from representative areas of negative margin and residual tumor were stained using H&E, MITF, MART-1, SOX10, and R21 and examined in a blinded fashion...
February 6, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29380216/prediction-model-for-two-year-risk-of-opioid-overdose-among-patients-prescribed-chronic-opioid-therapy
#17
Jason M Glanz, Komal J Narwaney, Shane R Mueller, Edward M Gardner, Susan L Calcaterra, Stanley Xu, Kristin Breslin, Ingrid A Binswanger
BACKGROUND: Naloxone is a life-saving opioid antagonist. Chronic pain guidelines recommend that physicians co-prescribe naloxone to patients at high risk for opioid overdose. However, clinical tools to efficiently identify patients who could benefit from naloxone are lacking. OBJECTIVE: To develop and validate an overdose predictive model which could be used in primary care settings to assess the need for naloxone. DESIGN: Retrospective cohort...
January 29, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29374491/prosthetic-energy-return-during-walking-increases-after-3-weeks-of-adaptation-to-a-new-device
#18
Samuel F Ray, Shane R Wurdeman, Kota Z Takahashi
BACKGROUND: There are many studies that have investigated biomechanical differences among prosthetic feet, but not changes due to adaptation over time. There is a need for objective measures to quantify the process of adaptation for individuals with a transtibial amputation. Mechanical power and work profiles are a primary focus for modern energy-storage-and-return type prostheses, which strive to increase energy return from the prosthesis. The amount of energy a prosthesis stores and returns (i...
January 27, 2018: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29364035/regulator-of-g-protein-signaling-12-modulates-the-dopamine-transporter-in-ventral-striatum-and-locomotor-responses-to-psychostimulants
#19
Joshua D Gross, Shane W Kaski, Adam B Schroer, Kimberley A Wix, David P Siderovski, Vincent Setola
Regulators of G protein signaling are proteins that accelerate the termination of effector stimulation after G protein-coupled receptor activation. Many regulators of G protein signaling proteins are highly expressed in the brain and therefore considered potential drug discovery targets for central nervous system pathologies; for example, here we show that RGS12 is highly expressed in microdissected mouse ventral striatum. Given a role for the ventral striatum in psychostimulant-induced locomotor activity, we tested whether Rgs12 genetic ablation affected behavioral responses to amphetamine and cocaine...
February 2018: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/29345864/naltrexone-and-disulfiram-treatment-response-in-veterans-with-alcohol-dependence-and-co-occurring-problem-gambling-features
#20
Jon E Grant, Marc N Potenza, Shane W Kraus, Ismene L Petrakis
BACKGROUND: Disordered gambling behavior frequently co-occurs with alcohol dependence and other psychiatric conditions. Using data from a previously published trial, we conducted secondary analyses to examine the influence of problem-gambling features on treatment outcome for alcohol dependence or co-occurring psychopathology assessed via DSM-IV criteria. METHODS: Two hundred fifty-four patients with alcohol dependence and co-occurring psychiatric disorders were treated for 12 weeks in an outpatient medication study conducted at 3 Veterans Administration outpatient clinics from October 1998 to March 2002...
November 2017: Journal of Clinical Psychiatry
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