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Bone nonunion

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https://www.readbyqxmd.com/read/29149352/prognostic-potential-of-markers-of-bone-turnover-in-delayed-healing-tibial-diaphyseal-fractures
#1
Malhar Kumar, Dnyaneshwar Shelke, Saumil Shah
INTRODUCTION: Clinical and radiographic examinations detect delayed or nonunion only after the event has occurred. Biochemical markers of bone turnover (BTMs) are promising laboratory tools that offer an early insight into the likelihood of delayed union. We hypothesized that BTMs display temporal variations following fractures and the behavior of BTMs differ between normal and delayed union of fractures. METHODS: This was a prospective study of patients with closed fracture of tibia treated with intramedullary, interlocking nailing...
November 17, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29145961/vertical-femoral-neck-fractures-in-young-adults-a-closed-fixation-strategy-using-a-transverse-cancellous-lag-screw
#2
João Antonio Matheus Guimarães, Leonardo Rosa Rocha, Tito Henrique Noronha Rocha, Danielle Cabral Bonfim, Rafaela Sartore da Costa, Amanda Dos Santos Cavalcanti, Carlos Rodrigo Roesler, Jamila Alessandra Perini Machado, Diego Pinheiro Aguiar, Maria Eugenia Leite Duarte
Vertical femoral neck fractures (Pauwels type III classification) in young adults generally occur as a consequence of high-energy trauma and are frequently seen in association with multiple injuries. Considering the controversies regarding the optimal fixation for this fracture, our aim was to evaluate the clinical outcome of a closed fixation strategy for vertical femoral neck fractures in young adults using two parallel and one transverse cancellous lag screws. This was a single-surgeon, prospective study including 20 young adults with average age of 38...
October 2017: Injury
https://www.readbyqxmd.com/read/29145253/anterior-endoscopically-assisted-bone-grafting-for-iatrogenic-distraction-of-odontoid-fracture-after-percutaneous-anterior-screw-fixation-a-case-report
#3
Ze-Xin Chen, Hui Zhang, Nai-Feng Tian, Xiang-Yang Wang, Yan Lin, Yao-Sen Wu
RATIONALE: The complication of iatrogenic distraction of odontoid fracture after anterior screw fixation has not been reported in the literature. We treated the patient with endoscopically assisted bone grafting with good results. The new technique was not reported in the management of odontoid fracture or nonunion before. PATIENT CONCERNS: A 22-year-old man presented with neck pain after a motorcycle crash. The cervical spine radiograph and computed tomographic scan demonstrated the base of dens displaced 2 mm anteriorly...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29142350/bone-scan-in-detection-of-biological-activity-in-nonhypertrophic-fracture-nonunion
#4
Sunny J Gandhi, Bhavdeep Rabadiya
Biological activity of the fracture site is very important factor in treatment planning of fracture nonunion. If no biological activity is detected, then an autologous bone graft can be supplemented or osteogenic supplementations, such as bone morphogenetic protein is given. If biological activity is present, then secure fixation is sufficient to achieve bony union. Biological activity of nonunions is usually assessed by conventional radiographs. The presence of callus formation is usually assessed as the presence of biological activity...
October 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/29137077/quality-of-life-and-complications-at-the-different-stages-of-bone-transport-for-treatment-infected-nonunion-of-the-tibia
#5
Hu Wang, Xing Wei, Ping Liu, Ya-Hui Fu, Peng-Fei Wang, Yu-Xuan Cong, Bin-Fei Zhang, Zhong Li, Jin-Lai Lei, Kun Zhang, Yan Zhuang
The aim of this study was to assess Physical Component Summary (PCS), Mental Component Summary (MCS) of the Mos 36-item Short Form Health Survey (SF-36) score, and the virtual Analogue Scale (VAS) of pain during the treatment period and the complication rate associated with infected nonunion of the tibia managed surgically by bone transport.This is a retrospective analysis of prospectively collected data in a consecutive patient cohort. Patients suffering from infected nonunion of the tibia were treated by bone transport from 2012 to 2014...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29132789/scaphoid-fracture-fixation-in-a-nonunion-model-a-biomechanical-study-comparing-3-types-of-fixation
#6
Avanthi Mandaleson, Stephen K Tham, Craig Lewis, David C Ackland, Eugene T Ek
PURPOSE: Union of a scaphoid fracture after fixation is influenced by various factors, one of which is fracture stability. This study aims to compare the biomechanical stability of 3 different types of scaphoid fracture fixation in a scaphoid nonunion model. METHODS: Thirty cadaveric scaphoid specimens were assigned to one of 3 different fixation groups: (1) single 3.0-mm compression screw, (2) two 2.2-mm screws, and (3) scaphoid plate. A 3-mm volar wedge osteotomy was created at the scaphoid waist to simulate a nonunion model...
November 11, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29132434/an-acetabular-preserving-procedure-for-pelvic-giant-cell-tumor-involving-partial-acetabulum
#7
Cong Xiao, Yong Zhou, Wenli Zhang, Yi Luo, Chongqi Tu
BACKGROUND: The management of pelvic giant cell tumors (GCTs) involving the acetabulum remains a challenge for surgeons on how to balance the relative benefits of minimizing recurrence and maintaining postoperative hip function. The present study was to present and evaluate the clinical indications, operative technique, and outcomes of pelvic GCTs involving partial acetabulum treated with multiplanar osteotomy and reconstruction of autogenous femoral head bone grafts combined with cementless total hip arthroplasty (THA)...
November 13, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29130879/vascularized-medial-femoral-condyle-graft-for-manubrium-nonunion-case-report-and-review-of-the-literature
#8
William R Aibinder, Michael E Torchia, Allen T Bishop, Alexander Y Shin
Fractures of the sternum are rare. Persistent nonunions, however, can lead to chronic pain and significant functional limitations. The vascularized medial femoral condyle is a versatile tool in the surgeon's armamentarium. Traditionally, it has been used as a thin corticoperiosteal graft in the treatment of nonunion of tubular bones. Its use as a structural corticocancellous graft has also been expanding. This report presents a case of a patient with a recalcitrant symptomatic nonunion of the manubrium treated with the unique combined corticoperiosteal and corticocancellous vascularized bone graft from the medial femoral condyle and reviews the literature concerning these uncommon nonunions...
October 2017: Journal of Surgical Orthopaedic Advances
https://www.readbyqxmd.com/read/29130872/a-retrospective-comparative-analysis-of-the-use-of-implantable-bone-stimulators-in-nonunions
#9
J Ryan Martin, George Vestermark, Brian Mullis, Jeffrey Anglen
This study details the use of implantable bone stimulators in the setting of nonunion. A retrospective comparative analysis was used to evaluate the efficacy of implantable bone stimulators in achieving union in the setting of atrophic or oligotrophic nonunion by two fellowship-trained orthopaedic trauma surgeons. Initially, 72 patients underwent surgical intervention for nonunion. Twenty-one patients had an implantable bone stimulator placed at the time of nonunion surgery. Thirty-eight patients had a minimum of 1-year follow-up...
October 2017: Journal of Surgical Orthopaedic Advances
https://www.readbyqxmd.com/read/29125707/vascularized-humeral-periosteal-flap-to-treat-lateral-humeral-condyle-nonunion-an-anatomical-study-and-report-of-two-successfully-treated-pediatric-cases
#10
S Sergi Barrera-Ochoa, Francisco Soldado, Alfonso Rodriguez-Baeza, Paula Diaz-Gallardo, Felipe Hodgson, Pablo S Corona, Jorge Knörr
PURPOSE: Nonunion is a common complication of lateral condyle humeral (LCH) fractures in children. In situ fixation with a screw and bone grafting is the classically-recommended method of treatment. The purpose of this study is to analyze the feasibility of obtaining a vascularized periosteal flap obtained from the lateral humerus and based on the posterior collateral radial vessels (PCRV). Second, to report the results after the application in two pediatric cases. METHODS: Periosteal branches of PCRV were studied in ten upper limbs from fresh human cadavers...
November 10, 2017: Microsurgery
https://www.readbyqxmd.com/read/29122282/masquelet-technique-with-external-locking-plate-for-recalcitrant-distal-tibial-nonunion
#11
Ching-Hou Ma, Yen-Chun Chiu, Kun-Ling Tsai, Yuan-Kun Tu, Cheng-Yo Yen, Chin-Hsien Wu
OBJECTIVE: In the present retrospective study, we aimed to analyze the results of treatment for recalcitrant distal tibial nonunion using Masquelet technique with locking plate as a definitive external fixator. MATERIALS: We included 15 consecutive cases of distal tibial nonunion treated at our hospital between January 2012 and December 2015. The reconstructive procedure comprised debridement of the nonunion site, deformity correction, stabilization with an external locked plate, defect filling with cement spacer for inducing membrane formation, and bone reconstruction using a cancellous bone autograft (Masquelet technique)...
October 26, 2017: Injury
https://www.readbyqxmd.com/read/29119287/smoking-and-obesity-influence-the-risk-of-nonunion-in-lateral-opening-wedge-closing-wedge-and-torsional-distal-femoral-osteotomies
#12
Franz Liska, Bernhard Haller, Andreas Voss, Julian Mehl, Florian B Imhoff, Lukas Willinger, Andreas B Imhoff
PURPOSE: Lateral distal femoral osteotomies (DFO) have recently been performed more frequently. In addition to realignment for varus and valgus deformity, the indication was extended with the introduction of torsional osteotomies in patellofemoral instability. The purpose of this study was to assess the general and technical risk factors for nonunion in lateral opening, closing and torsional DFO. METHODS: A total of 150 lateral DFO [98 opening wedge (LOWDFO) and 52 closing wedge (LCWDFO)] were analyzed in regard to potential risk factors for nonunion until plate removal...
November 8, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29115654/management-of-capitellar-fractures-with-open-reduction-and-internal-fixation-using-herbert-screws
#13
Asif Sultan, Omar Khursheed, Mohammad Rafiq Bhat, Hilal Ahmad Kotwal, Qazi Waris Manzoor
BACKGROUND: Capitellar fractures are rare elbow injuries and can cause severe limitation of function if not properly managed. Numerous treatments have evolved, from closed reduction and cast immobilization to open reduction and internal fixation (ORIF), so as to achieve a stable joint that allows early mobilization. We determined the functional outcomes of treating these fractures with ORIF using Herbert screws via an extensile lateral approach. METHODS: Fifteen patients with capitellar fractures were included in this retrospective study...
November 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29115642/combined-treatment-with-extracorporeal-shock%C3%A2-wave-therapy-and-bone-marrow-mesenchymal-stem-cell-transplantation-improves-bone-repair-in-a-rabbit-model-of-bone-nonunion
#14
Tao Fan, Guozhi Huang, Wen Wu, Rong Guo, Qing Zeng
The aim of the present study was to analyze whether extracorporeal shock‑wave therapy (ESWT) combined with bone marrow mesenchymal stem cell (BMMSC) transplantation improves bone repair in a rabbit bone nonunion model. ESWT combined with BMMSC effectively enhanced mechanical strength, fracture stiffness and histological scores, and increased alkaline phosphatase activity, and osteopontin, runt related transcription factor 2 and collagen type I α1 chain protein expression levels in a rabbit bone nonunion model...
November 6, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29114187/use-of-fibular-bone-graft-and-cancellous-screw-fixation-in-the-management-of-neglected-femur-neck-fractures-in-young-patients
#15
Ghulam Mustafa Kaim Khani, Kamran Hafeez, Muhammad Bux, Nusrat Rasheed, Naveed Ahmed, M Perwez Anjum
Objective: To present the clinical outcome of patients with neglected femur neck fracture treated with fibular bone graft. Methods: During May 2010-February 2013, 15 patients younger than 35 years of age with neglected fracture neck of femur were managed with non-vascularized fibular graft and cannulated screws. Fractures were classified according to Sandhu Classification. Hip function was assessed using Harris hip score. Results: Fifteen patients with mean age of 28...
November 2017: International Journal of Health Sciences
https://www.readbyqxmd.com/read/29113460/impact-of-age-on-human-adipose-stem-cells-for-bone-tissue-engineering
#16
Denis Dufrane
Bone nonunion is a pathological condition in which all bone healing processes have stopped, resulting in abnormal mobility between 2 bone segments. The incidence of bone-related injuries will increase in an aging population, leading to such injuries reaching epidemic proportions. Tissue engineering and cell therapy using mesenchymal stem cells (MSCs) have raised the possibility of implanting living tissue for bone reconstruction. Bone marrow was first proposed as the source of stem cells for bone regeneration...
September 2017: Cell Transplantation
https://www.readbyqxmd.com/read/29110711/radial-extracorporeal-shock-wave-therapy-is-efficient-and-safe-in-the-treatment-of-fracture-nonunions-of-superficial-bones-a-retrospective-case-series
#17
Paulo Kertzman, Nikolaus B M Császár, John P Furia, Christoph Schmitz
BACKGROUND: A substantial body of evidence supports the use of focused extracorporeal shock wave therapy (fESWT) in the non-invasive treatment of fracture nonunions. On the other hand, virtually no studies exist on the use of radial extracorporeal shock wave therapy (rESWT) for this indication. METHODS: We retrospectively analyzed 22 patients treated with rESWT for fracture nonunions of superficial bones that failed to heal despite initial surgical fixation in most cases...
November 6, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29109927/low-intensity-pulsed-ultrasound-and-halo-immobilization-is-an-effective-treatment-for-nonunion-following-traumatic-spondylolisthesis-of-the-axis
#18
Kohtaroh Oda, Tetsuro Ohba, Shigeto Ebata, Hirotaka Haro
This case report describes a unique case involving traumatic spondylolisthesis of the axis that resulted in nonunion, angulation, and displacement after conservative treatment with a cervical collar, but which was successfully achieved union with halo immobilization and low-intensity pulsed ultrasound (LIPUS). Halo immobilization of a traumatic spondylolisthesis in a 20-year-old patient, that previously failed to improve after wearing a cervical collar for 3 months, was immediately followed by treatment with a LIPUS device (SAFHS 4000J; Teijin Pharma, Tokyo, Japan) 20 minutes once daily to the right and left fracture sites which were located using fluoroscopic guidance...
October 2017: Journal of Neurological Surgery Reports
https://www.readbyqxmd.com/read/29109841/mandibular-reconstruction-with-lateral-tibial-bone-graft-an-excellent-option-for-oral-and-maxillofacial-surgery
#19
Ana Lucia Carpi Miceli, Livia Costa Pereira, Thiago da Silva Torres, Mônica Diuana Calasans-Maia, Rafael Seabra Louro
Autogenous bone grafts are the gold standard for reconstruction of atrophic jaws, pseudoarthroses, alveolar clefts, orthognathic surgery, mandibular discontinuity, and augmentation of sinus maxillary. Bone graft can be harvested from iliac bone, calvarium, tibial bone, rib, and intraoral bone. Proximal tibia is a common donor site with few reported problems compared with other sites. The aim of this study was to evaluate the use of proximal tibia as a donor area for maxillofacial reconstructions, focusing on quantifying the volume of cancellous graft harvested by a lateral approach and to assess the complications of this technique...
December 2017: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/29105591/treatment-of-the-scaphoid-humpback-deformity-is-correction-of-the-dorsal-intercalated-segment-instability-deformity-critical
#20
Christophe L Mathoulin, Margareta Arianni
Treatment of scaphoid fractures has been focused mainly on achieving union, with less attention to restoring normal scaphoid shape and orientation. Malalignment of one carpal bone will disrupt the kinetics of the entire wrist. The dorsal intercalated segment instability deformity associated with scaphoid waist nonunion is a nondissociative form of carpal instability. It has to be reduced in the treatment of scaphoid waist nonunions to avoid kinetic problems that will lead to arthritic changes. Computerized tomography scanning has become indispensable to visualize the humpback deformity clearly...
January 1, 2017: Journal of Hand Surgery, European Volume
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