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Lip and palatal cleft

Gregory S Antonarakis, Bryan D Tompson, David M Fisher
OBJECTIVE:   Maxillary growth in patients with cleft lip and palate is highly variable. The authors' aim was to investigate associations between preoperative cleft lip measurements and maxillary growth determined cephalometrically in patients with complete unilateral cleft lip and palate (cUCLP). DESIGN:   Retrospective cross-sectional study. PATIENTS:   Children with cUCLP. METHODS:   Preoperative cleft lip measurements were made at the time of primary cheiloplasty and available for each patient...
November 2016: Cleft Palate-craniofacial Journal
P Ha, C Li, B Shi
The purpose of this study was to investigate the key factors in relation to parent satisfaction with the primary repair of paediatric cleft lip. One hundred and ninety-five children born with cleft lip and/or palate aged between 3 months and 1 year were recruited, along with their caregivers. All patients underwent primary cleft lip repair, and a telephone interview was held with their main caregivers at 3 months postoperative. The level of satisfaction with each item included in a simplified Cleft Evaluation Profile was ascertained and recorded...
October 18, 2016: International Journal of Oral and Maxillofacial Surgery
Ádám Berniczei-Roykó, Jan-Hendrik Tappe, Axel Krinner, Tomasz Gredes, András Végh, Katona Gábor, Kamila Linkowska-Świdzińska, Ute Ulrike Botzenhart
BACKGROUND Cleft defects are one of the most frequent birth-deformities of the orofacial region and they are commonly associated with anomalies of the tooth structure, size, shape, formation, eruption, and tooth number. The aim of our study was to evaluate the prevalence, distribution, and potential association of combined hypodontia in cleft-affected patients with regard to all types of teeth in both jaws in the permanent dentition. MATERIAL AND METHODS This retrospective radiographic analysis included patients with various types of clefts treated orthodontically in the Department of Orofacial Orthopedics and Orthodontics at Heim Pàl Children's Hospital, Budapest...
October 21, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Myoung Seok Lee, Jeong Yeon Cho, Sang Youn Kim, Seung Hyup Kim, Joong Shin Park, Jong Kwan Jun
Purpose: The purpose of this study was to evaluate the feasibility and usefulness of sagittal color Doppler ultrasonography (CDUS) for the diagnosis of fetal cleft lip (CL) and cleft palate (CP). Methods: We performed targeted ultrasonography on 25 fetuses with CL and CP, taking coronal and axial images of the upper lip and maxillary alveolar arch in each case. The existence of defects in and malalignment of the alveolus on the axial image, hard palate defects on the midsagittal image, and flow-through defects on CDUS taken during fetal breathing or swallowing were assessed...
August 6, 2016: Ultrasonography
Suleyman Kutalmiş Buyuk, Mevlut Celikoglu, Yasin Atakan Benkli, Ahmet Ercan Sekerci
AIM: The aim of the study was to evaluate the transverse craniofacial morphology of the adolescent patients affected by unilateral cleft lip and palate (UCLP) and to compare the findings with age- and sex-matched control group without any cleft using their cone-beam computed tomography (CBCT) images. METHODS: The study sample (n = 56 patients; mean age: 14.35 ± 3.06 years) consisted of 26 UCLP (n = 26 patients; 10 women and 16 men; mean age: 13.70 ± 2...
October 2016: Journal of Craniofacial Surgery
Benjamin B Massenburg, Hillary E Jenny, Saurabh Saluja, John G Meara, Mark G Shrime, Nivaldo Alonso
BACKGROUND: Cleft lip and/or palate (CLP) is estimated to occur in 1 out of every 700 births, but for many people residing in low- and middle-income countries this deformity may be repaired late in life or not at all. This study aims to analyze worldwide provider-perceived barriers to the surgical repair of CLP in low- and middle-income countries. METHODS: From 2011 to 2014, Smile Train distributed a multiple-choice, voluntary survey to healthcare providers to identify areas of need in CLP care worldwide...
October 2016: Journal of Craniofacial Surgery
Peter A Lioufas, Michelle R Quayle, James C Leong, Paul G McMenamin
: To explore the potential viability and limitations of 3D printed models of children with cleft palate deformity. BACKGROUND: The advantages of 3D printed replicas of normal anatomical specimens have previously been described. The creation of 3D prints displaying patient-specific anatomical pathology for surgical planning and interventions is an emerging field. Here we explored the possibility of taking rare pediatric radiographic data sets to create 3D prints for surgical education...
September 2016: Plastic and Reconstructive Surgery. Global Open
Michael Alperovich, Lawrence E Brecht, Stephen M Warren
No abstract text is available yet for this article.
October 14, 2016: Journal of Craniofacial Surgery
Dario Bertossi, Claudia Corega, Armando Boccieri, Pasquale Procacci, Carmen Mortellaro, Pierfrancesco Nocini
: Secondary cleft lip nasal deformities corrective procedures are still a major concern for the maxillofacial surgeons. OBJECTIVE: The aim of this study was twofold, to present a new "anatomical balance" correction for the correction of secondary cleft nose deformities and to evaluate it through a long-term follow-up study. PARTICIPANTS: One hundred twenty patients with cleft lip and palate and secondary nasal tip deformities were recruited for this study...
October 14, 2016: Journal of Craniofacial Surgery
Hideyuki Suenaga, Asako Taniguchi, Kazumichi Yonenaga, Kazuto Hoshi, Tsuyoshi Takato
INTRODUCTION: Computer-assisted preoperative simulation surgery is employed to plan and interact with the 3D images during the orthognathic procedure. It is useful for positioning and fixation of maxilla by a plate. We report a case of maxillary retrusion by a bilateral cleft lip and palate, in which a 2-stage orthognathic procedure (maxillary advancement by distraction technique and mandibular setback surgery) was performed following a computer-assisted preoperative simulation planning to achieve the positioning and fixation of the plate...
October 4, 2016: International Journal of Surgery Case Reports
Ahmad S Burhan, Fehmieh R Nawaya
BACKGROUND: Cleft lip and palate (CLP) anomaly is one of the most prevalent congenital defects causing disturbances of dental arch dimensions. This study aimed at investigating differences in these dimensions between preschool children with cleft lip/palate and a matched control group representing healthy individuals with normal occlusion (NO). MATERIALS AND METHODS: The sample of this cross-sectional analytical study consisted of 108 plaster models of children aged from 4 to 5...
September 2016: Journal of the Egyptian Public Health Association
Anna Maria Pinto, Valentina Imperatore, Laura Bianciardi, Margherita Baldassarri, Paolo Galluzzi, Simone Furini, Giovanni Centini, Alessandra Renieri, Francesca Mari
Orofacial clefts are the most common congenital craniofacial anomalies and can occur as an isolated defect or be associated with other anomalies such as posterior fossa anomalies as a part of several genetic syndromes. We report two consecutive voluntary pregnancy interruptions in a nonconsanguineous couple following the fetal ultrasound finding of cleft lip and palate and posterior fossa anomalies confirmed by means of post-termination examination on the second fetus. The quantitative fluorescent PCR, the karyotype, and the comparative genomic hybridization-array analysis after amniocentesis were normal...
October 4, 2016: Clinical Dysmorphology
G J Roode, K-W Bütow, S Naidoo
To identify the pathogenic micro-organisms that had colonised preoperatively in clefts in the soft palate and oro-nasopharynx, we retrospectively studied the preoperative microbiological profiles of 200 infants who had had primary repair of all types of cleft in the soft palate. Data from a private practice that specialises in the repair of facial clefts were extracted randomly from patients' files. We analysed the results of the culture of preoperative swabs taken from clefts in the soft palate and oro-nasopharynx, and the resistance profile of organisms towards various antibiotics...
October 10, 2016: British Journal of Oral & Maxillofacial Surgery
Katherine Payne, Niall Davison, Alexander Thompson, Kevin O'Brien, Iain A Bruce
Children with a cleft palate (CP) have an increased tendency towards otitis media with effusion (OME) compared with other children; There are no epidemiological data available to indicate how many children within specific age groups with CP have OME, or will still have OME, after the current recommended 'watchful waiting' period of three-months before considering intervention; This study aimed to identify the proportion of 2-year olds with CP, or cleft lip and palate (CLP), that have a confirmed diagnosis of OME and the proportion of 2-year olds with CLP or CP that still have OME after a period of 3-months 'watchful waiting'; Using a structured elicitation exercise, this study identified that experts in the management of children with CP estimated that around 61% of 2-year olds would have a confirmed diagnosis of OME and 55% of these 2-year olds would still have OME after a period of 3-months watchful waiting; In the absence of data from a prospective cohort of children with CP the results from this study can be used as the foundation to inform the design of future prospective randomised trials of interventions for children with CP and OME: An elicitation exercise can be used to estimate the proportion of affected individuals when more definitive data is not available This article is protected by copyright...
October 15, 2016: Clinical Otolaryngology
Negar Salimi, Jolanta Aleksejūnienė, Edwin Yen, Angelina Loo
OBJECTIVE:   To examine the time trends and determinants of palatal fistula in children with different types of cleft at British Columbia's Children's Hospital between 1995 and 2012. METHODS:   A total of 558 medical charts of nonsyndromic patients with cleft lip and palate were eligible for the chart review. The occurrence of primary palatal fistula was assessed at any time throughout the patient's total observation period. Three types of clefts were recorded: unilateral cleft lip and palate (ULCLP), bilateral cleft lip and palate (BLCLP), and isolated cleft palate (ICP)...
October 14, 2016: Cleft Palate-craniofacial Journal
Bin Wang, Yuxi Zhou, Song Leng, Liyuan Zheng, Hong Lv, Fei Wang, Li-Hai Tan, Yimin Sun
Developmental dyslexia (DD) is a neurodevelopment disorder characterized by reading disabilities without apparent etiologies. Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a structural craniofacial malformation featured by isolated orofacial abnormalities. Despite substantial phenotypic differences, potential linkage between these two disorders has been suggested as prevalence of DD among NSCL/P patients was much higher than that in general populations. Previous neuroimaging studies observed impaired short-term memory in patients with DD and NSCL/P, respectively...
October 13, 2016: Journal of Human Genetics
Eva Hoffmannova, Šárka Bejdová, Jiri Borský, Ján Dupej, Veronika Cagáňová, Jana Velemínská
BACKGROUND: A new method of early neonatal cheiloplasty has recently been employed on patients having complete unilateral cleft lip and palate (cUCLP). We aimed to investigate (1) their detailed palatal morphology before surgery and growth during the 10 months after neonatal cheiloplasty, (2) the growth of eight dimensions of the maxilla in these patients, (3) the development of these dimensions compared with published data on noncleft controls and on cUCLP patients operated using later operation protocol (LOP; 6 months of age)...
November 2016: International Journal of Pediatric Otorhinolaryngology
Aurora Ibarra-Arce, Tania Albavera-Giles, Beatriz Zavaleta-Villa, Gabriela Ortiz de Zárate-Alarcón, Laura Flores-Peña, María Del Carmen Sierra-Romero, Mirza Romero-Valdovinos, Angélica Olivo-Díaz
OBJECTIVE: Non-syndromic cleft lip/palate malformation (CL/P) is one of the most common birth defects in humans and has a complex etiology involving genetic and environmental factors. Mutations in the MSX1 gene are critical during craniofacial development. The purpose of this study was to investigate the contribution of MSX1 gene polymorphisms to the risk of developing CL/P in a sample of Mexican patients. METHODS: The sample consisted of 282 subjects (69 cases and 213 relatives)...
November 2016: International Journal of Pediatric Otorhinolaryngology
Zhang Xuan, Yang Zhongpeng, Guo Yanjun, Dai Jiaqi, Zhu Yuchi, Shi Bing, Li Chenghao
OBJECTIVE: To assess the association between maternal active cigarette smoking and the risk of oral clefts in the offspring. STUDY DESIGN: Oral clefts are divided into three subgroups: total clefts, cleft lip with or without cleft palate (CL ± P), and cleft palate only (CP). Data from studies on different levels of smoking were gathered to examine the dose-response effect. RESULTS: The present meta-analysis included 29 case-control and cohort studies through Cochrane, PubMed, and Ovid Medline searches...
August 18, 2016: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
V Lebese, C Aldous, H L Malherbe
BACKGROUND: The National Department of Health in South Africa (SA) routinely collects congenital disorder (CD) data for its national CD surveillance system. The current system has been implemented since 2006, but no reports on the data collected, methodology, achievements or challenges have been published to date. OBJECTIVES: To ascertain the effectiveness of the current national CD surveillance system and its implementation. METHOD: A descriptive, retrospective study using an audit of the current database was undertaken to evaluate the number of notifications received, types of CDs reported and the quality of reporting across SA for data received from 2006 to 2014...
September 5, 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
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