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https://www.readbyqxmd.com/read/28729177/the-iowa-voiding-improvement-partnership-experience-early-observations-with-a-collaborative-pediatric-uro-psychologic-clinic
#1
K M Bonnett, L L Fuller, C S Cooper, A M Arlen, D W Storm
INTRODUCTION: Bladder and bowel dysfunction (BBD) are common problems in children presenting for pediatric urology referral. Psychiatric issues may be present in these children, making their treatment difficult. In 2013, the University of Iowa Voiding Improvement Partnership (VIP) Clinic was established for the treatment of these patients. STUDY OBJECTIVE: This study sought to evaluate early experience with this specialized clinic, to determine the pre-existing urologic and psychologic conditions seen in these clinic patients, and to evaluate the clinical outcomes after VIP treatment...
July 1, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28721462/-outpatient-specialist-treatment-%C3%A2-%C3%A2-116b-new-changes-pending-in-outpatient-uro-oncology
#2
REVIEW
A Schroeder
No abstract text is available yet for this article.
July 18, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28719043/implementation-rates-of-uro-oncology-multi-disciplinary-meeting-decisions
#3
Ned Kinnear, Riley Smith, Derek B Hennessey, Damien Bolton, Shomik Sengupta
OBJECTIVES: To assess implementation rates of the consensus plans made at the uro-oncology multidisciplinary meeting (MDM) of an Australian tertiary centre, and analyse obstacles to implementation. METHODS: A retrospective review was performed of all patients discussed at the uro-oncology MDM at our institution between 1 January to 30 June 2015. Rates of referral for MDM discussion following a new histological diagnosis of malignancy, categorised by tumour type, were assessed...
July 18, 2017: BJU International
https://www.readbyqxmd.com/read/28707840/erratum
#4
(no author information available yet)
L'article « L'urogériatrie du médecin généraliste » [ Frequent uro-geriatric symptoms : helpful tools for general practitioners], Rev Med Suisse 2016;12:2077-82 [PMID: 28700153] paru dans le numéro 541 du 30 novembre 2016 de la Revue médicale suisse, a également été coécrit par le Dr Caroline Carera Sager, Service d'urologie, HUG, Genève. Les auteurs sont donc : Drs Guillaume Altwegg, Jacques Klein, Grégory Wirth, Caroline Carera Sager et Pr Christophe E. Iselin.
December 14, 2016: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28706333/availability-of-pediatric-evaluated-formulations-in-serbia
#5
Bojana Božić, Sanja Stupar, Duško Stupar, Uroš Babić, Milica Bajčetić
OBJECTIVES: The aim of this study is to analyze the availability and coverage by health insurance reimbursement of pediatric formulations labeled for children up to the age of 12 in Serbia. To provide good insight in general availability of pediatric medicines, results were compared with the World Health Organization's (WHO) "Model List of Essential Medicines for Children" and with published evidence. MATERIALS AND METHODS: Sources of information about medicines are the Summary of Product Characteristics, National Health Insurance Fund (NHIF) Drug Lists, WHO Model Lists of Essential Medicines for Children, and Serbia's official drug registry (2013)...
March 2017: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/28700153/-frequent-uro-geriatric-symptoms-helpful-tools-for-general-practitioners
#6
Guillaume Altwegg, Jacques Klein, Grégory Wirth, Christophe E Iselin
Each developed country faces an aging population. Increase of age rises the risk to develop urologic pathology especially in men. Routine investigation and diagnostic of urologic pathology important, however must take into account the patient in his globality (including age, comorbidities, drug medication as well as sociocultural environment). The aim of this article is to help the general practitioner in taking decisions with frequent uro-geriatric symptoms. Bladder catheterization remains an invasive treatment and indication should be regularly re-evaluated...
November 30, 2016: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28699201/characterization-of-sugar-and-polyphenolic-diversity-in-floral-nectar-of-different-obla%C3%A4-inska-sour-cherry-clones
#7
Basem Guffa, Nebojša M Nedić, Dragana Č Dabić Zagorac, Tomislav B Tosti, Uroš M Gašić, Maja M Natić, Milica M Fotirić Akšić
'Oblačinska' sour cherry, an autochthonous cultivar, is the most planted cultivar in Serbian orchards. Since fruit trees in temperate zone reward insects by producing nectar which 'quality' affects the efficiency of insect pollination, the aim of this study was analyzing of sugars and polyphenolics in floral nectar of 16 'Oblačinska' sour cherry clones with different yielding potential. The contents of sugars and sugar alcohols were analyzed by ion chromatography, while polyphenolic profile was established using liquid chromatography - mass spectrometry technique (LC/MS)...
July 12, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28677107/a-french-retrospective-study-on-clinical-outcome-in-102-choroid-plexus-tumors-in-children
#8
A Siegfried, S Morin, C Munzer, M B Delisle, M Gambart, S Puget, C A Maurage, C Miquel, C Dufour, P Leblond, N André, D Figarella Branger, J Kanold, J-L Kemeny, C Icher, A Vital, E Uro Coste, A I Bertozzi
The aim of this study was to review and describe therapeutic approaches in children with choroid plexus tumor (CPT) based on a nationwide series. The World Health Organization classification subdivides these rare tumors into three histological subtypes corresponding to three grades of malignancy: low grade (grade I) choroid plexus papilloma (CPP), intermediate grade (grade II) atypical choroid plexus papilloma (aCPP) and high grade (grade III) choroid plexus carcinoma (CPC). This retrospective study included 102 French children younger than 18 years, treated from 2000 to 2012: 54 CPP, 26 aCPP and 22 CPC...
July 4, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28664838/treatment-of-antibody-mediated-rejection-of-kidney-grafts-with-bortezomib-and-or-rituximab-compared-to-standard-regimen-experience-of-slovene-national-center
#9
Teja Oblak, Jelka Lindič, Jakob Gubenšek, Radoslav Kveder, Andreja Aleš Rigler, Andrej Škoberne, Željka Večerić Haler, Špela Borštnar, Nuša Avguštin, Rafael Ponikvar, Gregor Mlinšek, Dušan Ferluga, Nika Kojc, Uroš Godnov, Damjan Kovač
BACKGROUND: The aim of our study was to determine outcomes of standard treatment of antibody-mediated rejection (ABMR) of kidney grafts as compared to the addition of bortezomib or rituximab. METHODS: The cohort of this retrospective study included patients treated for ABMR of kidney grafts at our national center in the period of 2005 - 2017, divided into two groups: standard (ST) group treated standardly with plasmapheresis or immunoadsorption, intravenous immunoglobulins, and corticosteroids, and BR group treated with the addition of bortezomib and/or rituximab...
2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28662320/an-approach-to-determine-the-prevalence-of-poor-mental-health-among-urban-and-rural-population-in-serbia-using-propensity-score-matching
#10
Milena Šantrić-Milićević, Nataša Rosić, Uroš Babić, Zorica Šupić-Terzić, Janko Janković, Jovana Todorović, Goran Trajković
OBJECTIVE: Studies about mental health among urban and rural residents are scarce. A limited number of studies report somewhat better mental health in rural settings, despite higher rates of suicides. The main objective of this study was to describe social conditions of the population of Serbia in rural and urban settlements and to assess the differences in the prevalence of mental health disorders. METHODS: Propensity score matching of urban and rural persons (2 × 3,569 persons) has eliminated confounding effects from social variables (age, gender, wealth index, education level, employment, family status) and self-rated health...
June 2017: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28660389/clinical-and-molecular-characterization-of-prader-willi-syndrome
#11
G N Sanjeeva, Madhuri Maganthi, Himabindu Kodishala, Rohit Kumar R Marol, Pooja S Kulshreshtha, Elisa Lorenzetto, Jayarama S Kadandale, Uros Hladnik, P Raghupathy, Meenakshi Bhat
OBJECTIVES: To describe the clinical presentations and molecular diagnosis to aid the clinicians in early diagnosis and appropriate management of Prader-Willi syndrome (PWS). METHODS: Thirty-four clinically diagnosed PWS cases were enrolled after obtaining informed consent/assent. Demographic details, clinical data and anthropometry were recorded using structured proforma. The facial dysmorphology was evaluated. Appropriate genetic testing was performed to confirm the diagnosis...
June 29, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28659719/somatic-mutation-analyses-in-studies-of-the-clonal-evolution-and-diagnostic-targets-of-prostate-cancer
#12
REVIEW
Dmitry S Mikhaylenko, Gennady D Efremov, Vladimir V Strelnikov, Dmitry V Zaletaev, Boris Y Alekseev
Prostate cancer (PC) is the most common uro-oncological disease in the global population and still requires a more efficient laboratory diagnosis. Point mutations of oncogenes and tumor sup-pressor genes are the most frequent molecular genetic events in carcinogenesis. The mutations are re-sponsible, to a great extent, for the clonal evolution of cancer and can be considered as primary candi-date molecular markers of PC. Using next-generation sequencing to analyze the mutations in PC, the main molecular PC subtypes were identified, which depended on the presence of fusion genes and FOXA1, CHD1, and SPOP point mutations; other driver mutations responsible for the progression of PC subclones were also characterized...
June 2017: Current Genomics
https://www.readbyqxmd.com/read/28655391/prevalence-and-risk-factors-for-nonvertebral-bone-fractures-in-kidney-transplant-recipients-a-single-center-retrospective-analysis
#13
Alexander Jerman, Jelka Lindič, Andrej Škoberne, Špela Borštnar, Maja Martinuč Bergoč, Uroš Godnov, Damjan Kovač
BACKGROUND: Complex and longstanding bone disease superimposed by harmful influences of immunosuppression is the reason for increased risk of bone fracture in kidney transplant recipients. The aim of our study was to analyze the incidence and prevalence of nonvertebral bone fractures and early (in the first post-transplant year) clinical and laboratory risk factors for suffering bone fracture in the long-term post-transplant period. METHODS: Clinical and laboratory data as well as bone mineral density (BMD) measurements of 507 first kidney transplant recipients who were transplanted in the period from 1976 to 2011 were analyzed...
June 28, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28652880/testosterone-monitoring-for-men-with-advanced-prostate-cancer-review-of-current-practices-and-a-survey-of-canadian-physicians
#14
REVIEW
Bobby Shayegan, Frédéric Pouliot, Alan So, John Fernandes, Joseph Macri
Androgen-deprivation therapy (ADT) is a standard of care in the treatment of advanced prostate cancer; however, testosterone monitoring practices for men undergoing ADT vary across Canada. Although a testosterone level of 1.7 nmol/L or lower has historically been defined as the accepted castrate level, newer assays with improved sensitivity have shown that both medical and surgical castration can suppress testosterone levels to below 0.7 nmol/L. This review explores the evidence supporting a redefinition of the castrate testosterone level as 0...
June 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28652879/are-renal-tumour-scoring-systems-better-than-clinical-judgement-at-predicting-partial-nephrectomy-complexity
#15
Ravi M Kumar, Luke T Lavallée, Darren Desantis, Sonya Cnossen, Ranjeeta Mallick, Ilias Cagiannos, Chris Morash, Rodney H Breau
INTRODUCTION: We aimed to determine how renal tumour scoring systems, such as RENAL, PADUA, and Centrality (C)-index, compare to clinical judgement at predicting time required for tumour removal and kidney reconstruction during partial nephrectomy. METHODS: A consecutive cohort of partial nephrectomy patients treated at The Ottawa Hospital, a tertiary care uro-oncological centre, was retrospectively reviewed. Preoperative axial images were reviewed by four experienced urological oncologists who independently rated the complexity of a partial nephrectomy from 1-10 to generate a clinical judgement score...
June 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28639505/rationale-and-design-of-the-multiethnic-pharmacogenomics-in-childhood-asthma-consortium
#16
Niloufar Farzan, Susanne J Vijverberg, Anand K Andiappan, Lambang Arianto, Vojko Berce, Natalia Blanca-López, Hans Bisgaard, Klaus Bønnelykke, Esteban G Burchard, Paloma Campo, Glorisa Canino, Bruce Carleton, Juan C Celedón, Fook Tim Chew, Wen Chin Chiang, Michelle M Cloutier, Denis Daley, Herman T Den Dekker, F Nicole Dijk, Liesbeth Duijts, Carlos Flores, Erick Forno, Daniel B Hawcutt, Natalia Hernandez-Pacheco, Johan C de Jongste, Michael Kabesch, Gerard H Koppelman, Vangelis G Manolopoulos, Erik Melén, Somnath Mukhopadhyay, Sara Nilsson, Colin N Palmer, Maria Pino-Yanes, Munir Pirmohamed, Uros Potočnki, Jan A Raaijmakers, Katja Repnik, Maximilian Schieck, Yang Yie Sio, Rosalind L Smyth, Csaba Szalai, Kelan G Tantisira, Steve Turner, Marc P van der Schee, Katia M Verhamme, Anke H Maitland-van der Zee
AIM: International collaboration is needed to enable large-scale pharmacogenomics studies in childhood asthma. Here, we describe the design of the Pharmacogenomics in Childhood Asthma (PiCA) consortium. MATERIALS & METHODS: Investigators of each study participating in PiCA provided data on the study characteristics by answering an online questionnaire. RESULTS: A total of 21 studies, including 14,227 children/young persons (58% male), from 12 different countries are currently enrolled in the PiCA consortium...
July 2017: Pharmacogenomics
https://www.readbyqxmd.com/read/28634226/phostine-pst3-1a-targets-mgat5-and-inhibits-glioblastoma-initiating-cell-invasiveness-and-proliferation
#17
Zahra Hassani, Ali Saleh, Soumaya Turpault, Salim Khiati, Willy Morelle, Jacques Vignon, Jean-Philippe Hugnot, Emmanuelle Uro-Coste, Philippe Legrand, Marcel Delaforge, Séverine Loiseau, Ludovic Clarion, Marc Lecouvey, Jean-Noël Volle, David Virieux, Jean-Luc Pirat, Hugues Duffau, Norbert Bakalara
Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor and accounts for a significant proportion of all primary brain tumors. Median survival after treatment is around 15 months. Remodeling of N-glycans by the N-acetylglucosamine glycosyltransferase (MGAT5) regulates tumoral development. Here, perturbation of MGAT5 enzymatic activity by the small-molecule inhibitor 3-Hydroxy-4,5-bis-benzyloxy-6-benzyloxymethyl-2-phenyl2-oxo-2λ5-[1,2]oxaphosphinane (PST3.1a) restrains GBM growth. In cell based assays it is demonstrated that PST3...
June 20, 2017: Molecular Cancer Research: MCR
https://www.readbyqxmd.com/read/28605963/a-molecular-and-haematological-study-of-theileria-equi-in-balkan-donkeys
#18
Dajana Davitkov, Darko Davitkov, Milos Vucicevic, Ljubodrag Stanisic, Milena Radakovic, Uros Glavinic, Zoran Stanimirovic
Equine piroplasmosis in donkeys has been recognised as a serious problem of major economic importance. The present molecular study is the first investigation of the presence of Theileria equi and Babesia caballi in Balkan donkeys and of the possible haematological alterations related to it. A total of 70 apparently healthy donkeys from Serbia were included in this study. The overall prevalence of T. equi infection in donkeys tested with multiplex PCR was 50%. There was no B. caballi-positive sample. Infections in donkeys included in this study seem to be associated with decreased red blood cell count, haemoglobin concentration, haematocrit and platelet count, and with increased white blood cell count, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration...
June 2017: Acta Veterinaria Hungarica
https://www.readbyqxmd.com/read/28595655/nuclear-protein-in-testis-carcinoma-of-the-mediastinum-a-case-report
#19
Gonçalo Boleto, Jeanne-Marie Perotin, Claire Launois, Emmanuelle Uro-Coste, Philippe Birembaut, Sandra Dury, Hervé Vallerand, François Lebargy, Gaëtan Deslée, Juliette Vella-Boucaud
BACKGROUND: Nuclear protein in testis carcinoma is a rare and very aggressive undifferentiated cancer which characteristically arises in the midline of the head, neck, and mediastinum. CASE PRESENTATION: We describe the case of a 46-year-old white woman admitted for superior vena cava syndrome revealing a mediastinal tumor. Pathological examination of specimens obtained by mediastinoscopy revealed an undifferentiated tumor with solid growth and positive immunoreactivity for p40 and negative immunoreactivity for cytokeratin markers...
June 9, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28594672/the-experiences-of-specialist-nurses-working-within-the-uro-oncology-multidisciplinary-team-in-the-united-kingdom
#20
Geoffrey Punshon, Ruth Endacott, Phillippa Aslett, Jane Brocksom, Louisa Fleure, Felicity Howdle, Morven Masterton, Anita O'Connor, Adrian Swift, Paul Trevatt, Alison Leary
PURPOSE: United Kingdom prostate cancer nursing care is provided by a variety of urology and uro-oncology nurses. The experience of working in multidisciplinary teams (MDT) was investigated in a national study. DESIGN: The study consisted of a national survey with descriptive statistics and thematic analysis. METHODS: A secondary analysis of a data subset from a UK whole population survey was undertaken (n = 285) of the specialist nursing workforce and the services they provide...
July 2017: Clinical Nurse Specialist CNS
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