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https://www.readbyqxmd.com/read/28340027/influence-of-long-term-in-vivo-exposure-debris-accumulation-and-archwire-material-on-friction-force-among-different-types-of-brackets-and-archwires-couples
#1
Uroš Mezeg, Jasmina Primožic
Objective: The aim was to assess the influence of long-term in vivo exposure, debris accumulation and archwire material on static and kinetic friction force among different types of brackets and archwires couples. Material and Methods: Friction testing was performed among four lower incisors' brackets, conventional and self-ligating (SL), coupled with either nickel-titanium or stainless steel archwires, as-received and in vivo exposed in 18 subjects. The friction testing was performed for a sliding distance of 14 mm at a speed of 10 mm/min, with a starting force of 0...
February 28, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/28339438/the-role-of-autonomic-function-in-exercise-induced-endogenous-analgesia-a-case-control-study-in-myalgic-encephalomyelitis-chronic-fatigue-syndrome-and-healthy-people
#2
Jessica Van Oosterwijck, Uros Marusic, Inge De Wandele, Lorna Paul, Mira Meeus, Greta Moorkens, Luc Lambrecht, Lieven Danneels, Jo Nijs
BACKGROUND: Patients with myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) are unable to activate brain-orchestrated endogenous analgesia (or descending inhibition) in response to exercise. This physiological impairment is currently regarded as one factor explaining post-exertional malaise in these patients. Autonomic dysfunction is also a feature of ME/CFS. OBJECTIVES: This study aims to examine the role of the autonomic nervous system in exercise-induced analgesia in healthy people and those with ME/CFS, by studying the recovery of autonomic parameters following aerobic exercise and the relation to changes in self-reported pain intensity...
March 2017: Pain Physician
https://www.readbyqxmd.com/read/28338302/use-of-the-uro-dyna-ct-in-endourology-the-new-frontier
#3
Fabio C Vicentini, Luiz A A Botelho, José L M Braz, Ernane S Almeida, Marcelo Hisano
We describe the use of the Uro Dyna-CT, an imaging system used in the operating room that produces real-time three-dimensional (3D) imaging and cross-sectional image reconstructions similar to an intraoperative computerized tomography, during a percutaneous nephrolithotomy and a contralateral flexible ureteroscopy in a complete supine position. A 65 year-old female patient had an incomplete calyceal staghorn stone in the right kidney and a 10mm in the left one. The procedure was uneventful and the intraoperative use of the Uro Dyna-CT identified 2 residual stones that were not found by digital fluoroscopy and flexible nephroscopy at the end of surgery, helping us to render the patient stone-free in one procedure, which was confirmed by a postoperative CT scan...
March 24, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28336286/robotic-surgery-in-uro-oncology-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#4
REVIEW
Daniel Steffens, Ruban Thanigasalam, Scott Leslie, Bharvi Maneck, Jane M Young, Michael Solomon
Robotic surgery represents a new horizon in minimally-invasive urological surgery. This systematic review of the literature and meta-analysis examines the effectiveness of robotic surgery compared with laparoscopic or open surgery for major uro-oncological procedures. 25 articles reported findings from 8 trials of prostatectomy (4 trials) and cystectomy (4 trials) including 1033 participants. Robotic surgery is comparable to laparoscopic or open surgery for oncological outcomes, overall complications, and provides somewhat better functional outcome, when compared to laparoscopic and open surgery...
March 20, 2017: Urology
https://www.readbyqxmd.com/read/28335238/selective-plasma-etching-of-polymeric-substrates-for-advanced-applications
#5
REVIEW
Harinarayanan Puliyalil, Uroš Cvelbar
In today's nanoworld, there is a strong need to manipulate and process materials on an atom-by-atom scale with new tools such as reactive plasma, which in some states enables high selectivity of interaction between plasma species and materials. These interactions first involve preferential interactions with precise bonds in materials and later cause etching. This typically occurs based on material stability, which leads to preferential etching of one material over other. This process is especially interesting for polymeric substrates with increasing complexity and a "zoo" of bonds, which are used in numerous applications...
June 7, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28334762/missense-uros-mutations-causing-congenital-erythropoietic-porphyria-reduce-uros-homeostasis-that-can-be-rescued-by-proteasome-inhibition
#6
Jean-Marc Blouin, Ganeko Bernardo-Seisdedos, Emma Sasso, Julie Esteve, Cécile Ged, Magalie Lalanne, Arantza Sanz-Parra, Pedro Urquiza, Hubert de Verneuil, Oscar Millet, Emmanuel Richard
Congenital erythropoietic porphyria (CEP) is an inborn error of heme biosynthesis characterized by uroporphyrinogen III synthase (UROS) deficiency resulting in deleterious porphyrin accumulation in blood cells responsible for hemolytic anemia and cutaneous photosensitivity. We analyzed here the molecular basis of UROS impairment associated with twenty nine UROS missense mutations actually described in CEP patients. Using a computational and biophysical joint approach we predicted that most disease-causing mutations would affect UROS folding and stability...
February 21, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28332005/levetiracetam-synergizes-with-gabapentin-pregabalin-duloxetine-and-selected-antioxidants-in-a-mouse-diabetic-painful-neuropathy-model
#7
Radica Stepanović-Petrović, Ana Micov, Maja Tomić, Uroš Pecikoza
RATIONALE: We have reported that levetiracetam, a novel anticonvulsant with analgesic properties, synergizes with ibuprofen/aspirin/paracetamol in a model of diabetic painful neuropathy (DPN). Most guidelines recommend gabapentin, pregabalin, and duloxetine as first- or second-line agents for DPN. OBJECTIVE: We examined the effects of combination treatment of first-/second-line analgesics with levetiracetam in a model of DPN. Additionally, the levetiracetam's combinations with antioxidants, low dose of aspirin, coenzyme Q10, or α-lipoic acid were evaluated...
March 22, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28299237/asymptomatic-urolithiasis-complicated-by-nephrocutaneous-fistula
#8
Marion Hamard, Gaël Amzalag, Christoph D Becker, Pierre-Alexandre Poletti
Asymptomatic spontaneous nephrocutaneous fistula is a rare and severe complication of chronic urolithiasis. We report a case of 56-year-old woman with a nephrocutaneous fistula (NFC) which developed from a superinfected urinoma following calyceal rupture due to an obstructing calculus in the left ureter. The patient was clinically asymptomatic and came to the emergency department for a painless left flank fluctuating mass. This urinoma was superinfected, with a delayed development of renal abscesses and perirenal phlegmon found on contrast-enhanced uro-computed tomography (CT), responsible for left renal vein thrombophlebitis and left psoas abscess...
2017: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/28298611/frequency-tuning-and-directional-sensitivity-of-tympanal-vibrations-in-the-field-cricket-gryllus-bimaculatus
#9
Martin J Lankheet, Uroš Cerkvenik, Ole N Larsen, Johan L van Leeuwen
Female field crickets use phonotaxis to locate males by their calling song. Male song production and female behavioural sensitivity form a pair of matched frequency filters, which in Gryllus bimaculatus are tuned to a frequency of about 4.7 kHz. Directional sensitivity is supported by an elaborate system of acoustic tracheae, which make the ears function as pressure difference receivers. As a result, phase differences between left and right sound inputs are transformed into vibration amplitude differences. Here we critically tested the hypothesis that acoustic properties of internal transmissions play a major role in tuning directional sensitivity to the calling song frequency, by measuring tympanal vibrations as a function of sound direction and frequency...
March 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28285981/novel-budesonide-particles-for-dry-powder-inhalation-dpi-prepared-using-a-microfluidic-reactor-coupled-with-ultrasonic-spray-freeze-drying
#10
Denis Saboti, Uroš Maver, Hak-Kim Chan, Odon Planinšek
Budesonide is a potent active pharmaceutical ingredient, often administered using respiratory devices such as metered dose inhalers (MDI), nebulizers and dry powder inhalers (DPI). Inhalable drug particles are conventionally produced by crystallization followed by milling. This approach tends to generate partially amorphous materials that require post-processing to improve the formulations' stability. Other methods involve homogenization or precipitation and often require the use of stabilizers, mostly surfactants...
March 9, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28282036/heterarchy-of-transcription-factors-driving-basal-and-luminal-cell-phenotypes-in-human-urothelium
#11
Carl Fishwick, Janet Higgins, Lawrence Percival-Alwyn, Arianna Hustler, Joanna Pearson, Sarah Bastkowski, Simon Moxon, David Swarbreck, Chris D Greenman, Jennifer Southgate
Cell differentiation is affected by complex networks of transcription factors that co-ordinate re-organisation of the chromatin landscape. The hierarchies of these relationships can be difficult to dissect. During in vitro differentiation of normal human uro-epithelial cells, formaldehyde-assisted isolation of regulatory elements (FAIRE-seq) and RNA-seq was used to identify alterations in chromatin accessibility and gene expression changes following activation of the nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) as a differentiation-initiating event...
March 10, 2017: Cell Death and Differentiation
https://www.readbyqxmd.com/read/28254473/precision-surgery-and-genitourinary-cancers
#12
R Autorino, F Porpiglia, P Dasgupta, J Rassweiler, J W Catto, L J Hampton, E Lima, V Mirone, I H Derweesh, F M J Debruyne
The landscape of the surgical management of urologic malignancies has dramatically changed over the past 20 years. On one side, better diagnostic and prognostic tools allowed better patient selection and more reliable surgical planning. On the other hand, the implementation of minimally invasive techniques and technologies, such as robot-assisted laparoscopy surgery and image-guided surgery, allowed minimizing surgical morbidity. Ultimately, these advances have translated into a more tailored approach to the management of urologic cancer patients...
February 20, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28249799/european-association-of-urology-position-statement-on-the-role-of-the-urologist-in-the-management-of-male-hypogonadism-and-testosterone-therapy
#13
EDITORIAL
Vincenzo Mirone, Frans Debruyne, Gert Dohle, Andrea Salonia, Nikolaos Sofikitis, Paolo Verze, Mikkel Fode, Christopher Chapple
Testosterone is a crucial sex hormone important for the health and development of men of all ages. It plays a role in the integrity and maintaining the function of several systems and organs. Testosterone deficiency is linked to a number of signs and symptoms potentially affecting every man in his complexity and masculinity, and is therefore of strong urological interest. For this reason, urologists should attach importance to the need for knowledge, vocational education, and training in this specific area.
February 26, 2017: European Urology
https://www.readbyqxmd.com/read/28243183/multidisciplinary-management-of-sexual-dysfunction-perineal-pain-and-elimination-dysfunction-in-a-woman-with-multiple-sclerosis
#14
Michela Miletta, Fabrizio Bogliatto, Leonardo Bacchio
BACKGROUND: Multiple sclerosis (MS) is a chronic disease that commonly affects young women and is associated with sexual dysfunction (SD) and lower anourogenital dysfunction, which affect quality of life. We evaluated the importance of an integrated multidisciplinary approach in the Lower Female Ano-Uro-Genital Network (LFAUGN) to manage a variety of complex symptoms. METHODS: A 40-year-old woman with MS and primary concerns about perineal pain and SD was treated by a trained midwife from the LFAUGN and a physical therapist after a multidisciplinary diagnostic process that included gynecologic evaluation for perineal pain and SD, physiatric assessment, urologic assessment for bladder retention (BR), and surgical examination for obstructed defecation syndrome (ODS)...
January 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28225537/laryngeal-sensitivity-testing-in-youth-with-exercise-inducible-laryngeal-obstruction
#15
Irena Hočevar-Boltežar, Uroš Krivec, Maja Šereg-Bahar
Exercise-inducible laryngeal obstruction (EILO) has been recognized as a not rare respiratory problem in youth practicing sports. The aim of the study was to test the mechanosensitivity of the larynx, and to identify the factors affecting it in a group of youth with proven EILO. Laryngeal sensory testing was performed in 54 adolescents and young adults with EILO. Laryngeal mucosal alterations were assessed according to the Reflux Finding Score (RFS). The data concerning diseases possibly affecting the upper airway, findings of previously performed flexible videolaryngoscopy during exercise, and RFS score were compared between the participants with laryngeal hyposensitivity and those with normal sensitivity...
February 20, 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28220328/the-provision-of-dietary-and-physical-activity-advice-for-men-diagnosed-with-prostate-cancer-a-qualitative-study-of-the-experiences-and-views-of-health-care-professionals-patients-and-partners
#16
Eileen Sutton, Lucy E Hackshaw-McGeagh, Jonathan Aning, Amit Bahl, Anthony Koupparis, Raj Persad, Richard M Martin, J Athene Lane
PURPOSE: To explore the views and experiences of health care professionals (HCPs), men diagnosed with localised prostate cancer and their partners about the provision of advice on diet and physical activity after diagnosis and treatment for localised prostate cancer. METHODS: Semi-structured in-depth interviews with ten HCPs (Consultant Urological Surgeons, Uro-Oncology Clinical Nurse Specialists and Allied Health Professionals: see Table 1) and sixteen men diagnosed with localised prostate cancer and seven of their partners...
February 20, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28205027/risk-factors-affecting-unplanned-reoperation-after-laparoscopic-gastrectomy-for-gastric-cancer-experience-from-a-high-volume-center
#17
Ping Li, Chang-Ming Huang, Ru-Hong Tu, Jian-Xian Lin, Jun Lu, Chao-Hui Zheng, Jian-Wei Xie, Jia-Bin Wang, Qi-Yue Chen, Long-Long Cao, Mi Lin
BACKGROUND: To evaluate the risk factors affecting unplanned reoperation (URO) after laparoscopic gastrectomy (LAG) for gastric cancer (GC) and establish a model to predict URO preoperatively. STUDY DESIGN: Between May 2007 and December 2014, we prospectively collected and retrospectively analyzed the data of 2608 GC patients who underwent LAG. Among them, 2580 patients not requiring an URO were defined as the Non-URO group, and 28 patients requiring an URO were defined as the URO group...
February 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28201752/characteristics-of-h3-k27m-mutant-gliomas-in-adults
#18
David Meyronet, Maud Esteban-Mader, Charlotte Bonnet, Marie-Odile Joly, Emmanuelle Uro-Coste, Alexandra Amiel-Benouaich, Fabien Forest, Cécilia Rousselot-Denis, Fanny Burel-Vandenbos, Véronique Bourg, Jacques Guyotat, Tanguy Fenouil, Anne Jouvet, Jérôme Honnorat, François Ducray
No abstract text is available yet for this article.
February 13, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/28192608/testis-sparing-surgery-for-treatment-of-small-testicular-lesions-is-it-feasible-even-in-germ-cell-tumors
#19
Nebojsa Bojanic, Uros Bumbasirevic, Gordana Bojanic, Ivan Vukovic, Bogomir Milojevic, Tatjana Pekmezovic
BACKGROUND AND OBJECTIVES: To evaluate the results of testis-sparing surgery (TSS) in patients, with small testicular lesions and a normal contralateral testicle. METHODS: In all, 28 patients were treated with TSS for small testicular lesions and a normal contralateral testicle. TSS was considered in patients with testicular lesions smaller than 2 cm and no evidence of metastatic disease. RESULTS: The mean age of patients was 35.3 ± 7...
March 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28161695/computerized-cognitive-training-and-brain-derived-neurotrophic-factor-during-bed-rest-mechanisms-to-protect-individual-during-acute-stress
#20
Angelina Passaro, Cecilia Soavi, Uros Marusic, Enrico Rejc, Juana M Sanz, Mario L Morieri, Edoardo Dalla Nora, Voyko Kavcic, Marco V Narici, Carlo Reggiani, Gianni Biolo, Giovanni Zuliani, Stefano Lazzer, Rado Pišot
Acute stress, as bed rest, was shown to increase plasma level of the neurotrophin brain-derived neurotrophic factor (BDNF) in older, but not in young adults. This increase might represent a protective mechanism towards acute insults in aging subjects. Since computerized cognitive training (CCT) is known to protect brain, herein we evaluated the effect of CCT during bed rest on BDNF, muscle mass, neuromuscular function and metabolic parameters. The subjects that underwent CCT did not show an increase of BDNF after bed rest, and showed an anti-insular modification pattern in metabolism...
February 3, 2017: Aging
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