keyword
MENU ▼
Read by QxMD icon Read
search

Uro

keyword
https://www.readbyqxmd.com/read/29679497/ewsr1-patz1-gene-fusion-may-define-a-new-glioneuronal-tumor-entity
#1
Aurore Siegfried, Audrey Rousseau, Claude-Alain Maurage, Sarah Pericart, Yvan Nicaise, Frederic Escudie, David Grand, Alix Delrieu, Anne Gomez-Brouchet, Sophie Le Guellec, Camille Franchet, Sergio Boetto, Matthieu Vinchon, Jean-Christophe Sol, Franck-Emmanuel Roux, Valerie Rigau, Anne-Isabelle Bertozzi, David Tw Jones, Dominique Figarella-Branger, Emmanuelle Uro-Coste
We investigated the challenging diagnostic case of a ventricular cystic glioneuronal tumor with papillary features, by RNA sequencing using the Illumina TruSight RNA Fusion panel. We did not retrieve the SLC44A1-PRKCA fusion gene specific for papillary glioneuronal tumor, but an EWSR1-PATZ1 fusion transcript. RT-PCR followed by Sanger sequencing confirmed the EWSR1-PATZ1 fusion. It matched with canonic EWSR1 fusion oncogene, juxtaposing the entire N terminal transcriptional activation domain of EWSR1 gene and the C terminal DNA binding domain of a transcription factor gene, PATZ1...
April 21, 2018: Brain Pathology
https://www.readbyqxmd.com/read/29663608/the-effects-of-hexachloronaphthalene-on-selected-parameters-of-heme-biosynthesis-and-systemic-toxicity-in-female-wistar-rats-after-90-day-oral-exposure
#2
Michal Klimczak, Adam Darago, Elzbieta Bruchajzer, Katarzyna Domeradzka-Gajda, Maciej Stepnik, Katarzyna Kuzajska, Anna Kilanowicz
Hexachloronaphthalenes (HxCNs) are the most toxic congeners of polychlorinated naphthalenes, a group of compounds lately included into the list of persistent organic pollutants (POPs). This study presents the effects of 90-day intragastric administration of HxCN to female Wistar rats at doses of 0.03, 0.1, and 0.3 mg/kg body weight. The study examined selected parameters of the heme synthesis pathway, oxidative stress, hepatic cytochromes level, and basic hematology indicators. A micronucleus test was also performed...
April 16, 2018: Environmental Toxicology
https://www.readbyqxmd.com/read/29657068/safety-and-efficacy-of-day-case-percutaneous-nephrolithotomy-a-systematic-review-from-european-society-of-uro-technology
#3
REVIEW
Patrick Jones, Grace Bennett, Alexios Dosis, Amelia Pietropaolo, Robert Geraghty, Omar Aboumarzouk, Andreas Skolarikos, Bhaskar K Somani
CONTEXT: Day case or ambulatory percutaneous nephrolithotomy (PCNL) has risen over the last few years with the aim of discharging patients within 24h. OBJECTIVE: We perform a systematic review of literature to evaluate the outcomes of day-case PCNL surgery. EVIDENCE ACQUISITION: A Cochrane style search was performed and the following bibliographic databases were accessed: PubMed, Science Direct, Scopus, and Web of Science. This was carried out in accordance with the Preferred Reporting Items for Systematic reviews and Meta-analyses (PRISMA) guidelines...
April 12, 2018: European Urology Focus
https://www.readbyqxmd.com/read/29649957/tissue-engineered-neo-urinary-conduit-from-decellularized-trachea
#4
Anirudha Anirudhasingh Gmail Com Singh, David Lee, Harrison Jeong, Christine Yu, Jiuru Li, ChenHao Fang, Praveena Sabnekar, Xiaopu Liu, Takahiro Yoshida, Nikolai Sopko, Trinity Bivalacqua
Decellularized tissues have been increasingly popular for constructing scaffolds for tissue engineering applications due to their beneficial biological compositions and mechanical properties. It is therefore natural to consider decellularized trachea for construction of tissue-engineered trachea as well as other tubular organs. A neo-urinary conduit (NUC) is such a tubular organ that works as a passage for urine removal in bladder cancer patients who need a urinary diversion after their diseased bladder is removed...
April 13, 2018: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/29629389/promoting-evidence-informed-policymaking-through-capacity-enhancement-in-implementation-research-for-health-researchers-and-policymakers-in-nigeria-a-cross-sectional-study
#5
Chigozie Jesse Uneke, Abel Ebeh Ezeoha, Henry Chukwuemeka Uro-Chukwu
BACKGROUND: Capacity constraints on implementation research among policymakers and researchers are a major challenge to the evidence to policy link. This study was designed to bring together senior policymakers and researchers in Nigeria to consider issues around research-to-policy interface and enhance their capacity on implementation research. METHODS: The design was a cross-sectional study. A 3-day joint implementation research workshop was held for policymakers and researchers using World Health Organization/TDR Implementation Research Toolkit...
2018: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/29622824/traditional-medicines-and-alternative-practice-in-the-management-of-prostate-diseases-in-southern-ghana
#6
Mathew Y Kyei, George O Klufio, Ali Ayamba, Sherif Mohammed
Objective: This study was aimed at identifying Ghanaian traditional medicines used for the management of prostate diseases and their constituents. Reviews of studies conducted on them are also presented. Methodology: This was a prospective study. Traditional Medicine samples from consecutive patients with either lower urinary symptoms (LUTS) presenting at the Urology Unit of the Korle Bu Teaching Hospital (KBTH) in Accra from January 2015 to June 2016 and had a prior treatment with traditional medicines, had the samples retrieved...
September 2017: Ghana Medical Journal
https://www.readbyqxmd.com/read/29611869/contracting-out-to-improve-the-use-of-clinical-health-services-and-health-outcomes-in-low-and-middle-income-countries
#7
REVIEW
Willem A Odendaal, Kim Ward, Jesse Uneke, Henry Uro-Chukwu, Dereck Chitama, Yusentha Balakrishna, Tamara Kredo
BACKGROUND: Contracting out of governmental health services is a financing strategy that governs the way in which public sector funds are used to have services delivered by non-governmental health service providers (NGPs). It represents a contract between the government and an NGP, detailing the mechanisms and conditions by which the latter should provide health care on behalf of the government. Contracting out is intended to improve the delivery and use of healthcare services. This Review updates a Cochrane Review first published in 2009...
April 3, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29611673/non-conservative-management-of-simple-renal-cysts-in-adults-a-comprehensive-review-of-literature
#8
Ahmed Eissa, Ahmed El Sherbiny, Eugenio Martorana, Giacomo M Pirola, Stefano Puliatti, Michele Scialpi, Salvatore Micali, Bernardo Rocco, Evangelos Liatsikos, Alberto Breda, Francesco Porpiglia, Giampaolo Bianchi
INTRODUCTION: Renal cysts are common findings in nearly 10% of general population. According to Bosniak classification, they are classified into simple and complex renal cysts based on their CT characteristics. The majority of simple renal cysts are asymptomatic and require no intervention. Once they become symptomatic or complicated, a non-conservative management should be considered. EVIDENCE ACQUISITION: This paper is a narrative review of existing manuscripts regarding the non-conservative management of renal cysts...
April 2018: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29603035/clinical-characteristics-of-infections-caused-by-mycoplasma-pneumoniae-p1-genotypes-in-children
#9
Jasna Rodman Berlot, Uroš Krivec, Marina Praprotnik, Tatjana Mrvič, Rok Kogoj, Darja Keše
Mycoplasma pneumoniae (M. pneumoniae) isolates can be classified into two major genetic groups, P1 type 1 (MP1) and P1 type 2 (MP2), based on the DNA sequence of the P1 adhesion protein gene. The aim of our study was to determine if M. pneumoniae P1 genotype is associated with disease manifestation and severity of acute M. pneumoniae infection. We compared epidemiological and clinical data of children infected with either MP1 or MP2. In addition, we separately analysed data of patients presenting with individual manifestations of M...
March 30, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29595040/male-infertility-as-a-proxy-of-the-overall-male-health-status
#10
Paolo Capogrosso, Eugenio Ventimiglia, Luca Boeri, Walter Cazzaniga, Francesco Chierigo, Francesco Montorsi, Andrea Salonia
INTRODUCTION: Male infertility (MI) has been widely associated with different comorbid conditions. The aim of this review is to summarize the available evidences investigating the link between MI cancer, chronic non-malignant conditions and overall health. EVIDENCE ACQUISITION: A literature search has been conducted using the MEDLINE/PubMed and Scopus databases for English-language original and review articles and selecting publications from January 2007 to June 2017, although highly regarded older publications were also considered...
March 28, 2018: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29589154/identification-of-curable-high-risk-prostate-cancer-using-radical-prostatectomy-alone-who-are-the-good-candidates-for-undergoing-radical-prostatectomy-among-patients-with-high-risk-prostate-cancer
#11
Kazuhiro Nagao, Hideyasu Matsuyama, Hiroaki Matsumoto, Takahito Nasu, Mitsutaka Yamamoto, Yoriaki Kamiryo, Yoshikazu Baba, Akinobu Suga, Yasuhide Tei, Satoru Yoshihiro, Akihiko Aoki, Tomoyuki Shimabukuro, Keiji Joko, Shigeru Sakano, Kimio Takai, Shiro Yamaguchi, Jumpei Akao, Seiji Kitahara
BACKGROUND: Currently, there is no consensus regarding which patients with high-risk prostate cancer (PCa) would benefit the most by radical prostatectomy (RP). We aimed to identify patients with high-risk PCa who are treatable by RP alone. METHODS: We retrospectively reviewed data on 315 patients with D'Amico high-risk PCa who were treated using RP without neoadjuvant or adjuvant therapy at the institutions of the Yamaguchi Uro-Oncology Group between 2009 and 2013...
March 27, 2018: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29587739/prevalence-and-antimicrobial-susceptibility-of-asymptomatic-bacteriuria-among-women-with-pelvic-organ-prolapse-in-abakaliki-south-east-nigeria
#12
K C Ekwedigwe, I Sunday-Adeoye, M O Eliboh, M E Isikhuemen, H Uro-Chukwu, P Ezeonu, A B C Daniyan, E N Yakubu
BACKGROUND: Pelvic organ prolapse (POP) is the herniation of pelvic organs from its anatomical confines, and it is of considerable importance to the practicing gynaecologist in middle and low income countries. It is commonly associated with, urinary tract infection (UTI), both symptomatic and asymptomatic due to anatomical and physiological changes. The aim of this study was to determine the prevalence of asymptomatic bacteriuria among women with pelvic organ prolapse, to know the organisms commonly implicated and the sensitivity pattern...
March 27, 2018: BMC Women's Health
https://www.readbyqxmd.com/read/29584705/particulate-guanylyl-cyclase-a-cgmp-signaling-pathway-in-the-kidney-physiologic-and-therapeutic-indications
#13
REVIEW
Yang Chen, John C Burnett
The particulate guanylyl cyclase A (pGC-A)/cGMP pathway plays important roles in regulating renal physiological function and as well as in counteracting pathophysiological conditions. Naturally occurring peptide pGC-A activators consist of atrial natriuretic peptide (ANP), b-type NP (BNP), and urodilatin (URO). These activators bind and activate pGC-A, generating the second messenger cyclic 3',5' guanosine monophosphate (cGMP). Cyclic GMP binds to downstream pathway effector molecules including protein kinase G (PKG), cGMP-gated ion channels, and phosphodiesterases (PDEs)...
March 27, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29573596/lemierre-s-syndrome-following-perianal-abscess-a-case-report
#14
Qusai Aljarrah, Yara Khazaleh, Mooath Al-Jarrah, Jordan W Oldbury, Ahmad K Abou-Foul
INTRODUCTION: Lemierre's syndrome (LS) is a rare and life-threatening condition characterized by suppurative thrombophlebitis of the internal jugular vein (IJV), and a history of head and neck (H&N) sepsis. LS is usually caused by Fusobacterium necrophorum, which is part of the normal flora in the oro-pharynx, and the digestive and urogenital tracts. We here report the first case of LS following perianal sepsis. PRESENTATION OF CASE: A 60-year-old man with a painful left neck swelling, dysphagia and worsening sepsis was referred from a peripheral unit where he had an incision and drainage of a perianal abscess a week earlier...
March 16, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29566085/urine-metabolome-in-women-with-chlamydia-trachomatis-infection
#15
Claudio Foschi, Luca Laghi, Antonietta D'Antuono, Valeria Gaspari, Chenglin Zhu, Nicolò Dellarosa, Melissa Salvo, Antonella Marangoni
The aim of this study was to characterize the urine metabolome of women with Chlamydia trachomatis (CT) uro-genital infection (n = 21), comparing it with a group of CT-negative subjects (n = 98). By means of a proton-based nuclear magnetic resonance (1H-NMR) spectroscopy, we detected and quantified the urine metabolites of a cohort of 119 pre-menopausal Caucasian women, attending a STI Outpatients Clinic in Italy. In case of a CT positive result, CT molecular genotyping was performed by omp1 gene semi-nested PCR followed by RFLP analysis...
2018: PloS One
https://www.readbyqxmd.com/read/29557620/-congenital-erythropoietic-porphyria-case-report-and-management-recommendations
#16
Claudia Salomone B, Isabel Ogueta C, Carlos Reyes V, Gloria Durán S, Noemí Aguirre, Angélica Wietstruck
Congenital erythropoietic porphyria is an extremely rare, autosomal recessive, non-acute cutaneous porphyria, caused by uroporphyrinogen III synthase deficiency, codificated by UROS gene on the chromosome 10q26.2. Porphyrins deposit in cornea, bones and teeth. The first symptoms could be manifested in early childhood, with skin fragility, vesicles and bullae. Severe course produces acral tissues mutilation, eye involvement, hemolytic anemia and hypersplenism. The treatment is complex and it is based in the photoprotection...
April 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29557276/non-physical-approaches-to-counteract-age-related-functional-deterioration-applications-for-rehabilitation-and-neural-mechanisms
#17
Uros Marusic, Sidney Grosprêtre
Normal and pathological ageing are associated with several motor impairments that reduce quality of life and represent a general challenge for public healthcare systems. Consequently, over the past decades, many scientists and physiotherapists dedicated their research to the development and improvement of safe and costless methods to counteract the progressive decline of motor functions with age. The urgency of finding new and easy to implement methods is even more paramount in case of acute pathologies (e...
March 20, 2018: European Journal of Sport Science
https://www.readbyqxmd.com/read/29556486/differences-in-clinical-outcome-between-docetaxel-and-abiraterone-acetate-as-the-first-line-treatment-in-chemo-na%C3%A3-ve-metastatic-castration-resistant-prostate-cancer-patients-with-or-without-the-ineligible-clinical-factors-of-the-cou-aa-302-study
#18
Darren M C Poon, Kuen Chan, Siu H Lee, Tim W Chan, Henry Sze, Eric K C Lee, Daisy Lam, Michelle F T Chan
Background: This study aimed to compare the efficacy of abiraterone acetate (AA) versus docetaxel (T) as first-line treatment in chemo-naïve metastatic castration-resistant prostate cancer (mCRPC) patients with or without the ineligible factors of the COU-AA-302 study (presence of visceral metastases, symptomatic disease, and/or Eastern Cooperative Oncology Group performance status ≥ 2). Materials and methods: The clinical records of chemo-naïve mCRPC patients who received AA in six public oncology centers or T in two of these centers between 2003 and 2014 were reviewed...
March 2018: Prostate International
https://www.readbyqxmd.com/read/29549916/comprehensive-genetic-study-of-fatty-acids-helps-explain-the-role-of-noncoding-inflammatory-bowel-disease-associated-snps-and-fatty-acid-metabolism-in-disease-pathogenesis
#19
Gregor Jezernik, Uroš Potočnik
Fatty acids and their derivatives play an important role in inflammation. Diet and genetics influence fatty acid profiles. Abnormalities of fatty acid profiles have been observed in inflammatory bowel diseases (IBD), a group of complex diseases defined by chronic gastrointestinal inflammation. IBD associated fatty acid profile abnormalities were observed independently of nutritional status or disease activity, suggesting a common genetic background. However, no study so far has attempted to look for overlap between IBD loci and fatty acid associated loci or investigate the genetics of fatty acid profiles in IBD...
March 2018: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/29549606/gonococcal-cellulitis-an-un-friendly-bite
#20
Amos Lal, Alwyn Rapose
BACKGROUND: Gonococcal infection can present with wide spectrum of symptoms, most commonly involving the genitals. This case highlights a rare presentation of Neisseria gonorrhoeae infection primarily with skin involvement without uro-genital disease. CASE: A 33-year-old male was admitted to the hospital with complaints of painful swelling of his penis. In the emergency room, he underwent incision and drainage of the abscess under local anaesthesia. After microbiological evaluation, he was found to have skin abscess caused by N...
March 16, 2018: Infection
keyword
keyword
97984
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"