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eating disorder and anxiety

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https://www.readbyqxmd.com/read/27914942/is-there-a-role-for-ghrelin-in-central-dopaminergic-systems-focus-on-nigrostriatal-and-mesocorticolimbic-pathways
#1
REVIEW
Alicia Stievenard, Mathieu Méquinion, Zane B Andrews, Alain Destée, Marie-Christine Chartier-Harlin, Odile Viltart, Christel C Vanbesien-Mailliot
The gastro-intestinal peptide ghrelin has been assigned many functions. These include appetite regulation, energy metabolism, glucose homeostasis, intestinal motility, anxiety, memory or neuroprotection. In the last decade, this pleiotropic peptide has been proposed as a therapeutic agent in gastroparesis for diabetes and in cachexia for cancer. Ghrelin and its receptor, which is expressed throughout the brain, play an important role in motivation and reward. Ghrelin finely modulates the mesencephalic dopaminergic signaling and is thus currently studied in pathological conditions including dopamine-related disorders...
November 30, 2016: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/27914473/effectiveness-of-enhanced-cognitive-behavioral-therapy-cbt-e-for-eating-disorders-study-protocol-for-a-randomized-controlled-trial
#2
Martie de Jong, Kees Korrelboom, Iris van der Meer, Mathijs Deen, Hans W Hoek, Philip Spinhoven
BACKGROUND: While eating disorder not otherwise specified (EDNOS) is the most common eating disorder (ED) diagnosis in routine clinical practice, no specific treatment methods for this diagnosis have yet been developed and studied. Enhanced cognitive behavioral therapy (CBT-E) has been described and put to the test as a transdiagnostic treatment protocol for all EDs, including EDNOS. Initial research in the UK suggests that CBT-E is more effective for EDs, especially bulimia nervosa (BN) and EDNOS, than the earlier version of CBT...
December 3, 2016: Trials
https://www.readbyqxmd.com/read/27904991/eat-up%C3%A2-family-centered-feeding-intervention-to-promote-food-acceptance-and-decrease-challenging-behaviors-a-single-case-experimental-design-replicated-across-three-families-of-children-with-autism-spectrum-disorder
#3
Joanna Cosbey, Deirdre Muldoon
This study evaluated the effectiveness of a family-centered feeding intervention, Easing Anxiety Together with Understanding and Perseverance (EAT-UP™), for promoting food acceptance of children with autism spectrum disorder at home. A concurrent multiple-baseline design was used with systematic replication across three families. Baseline was followed by an 'Intervention-Coaching' phase and then an 'Intervention-Independent' phase. Using direct observation and pre- and post-intervention questionnaires, data on acceptance of less preferred foods and challenging mealtime behaviors were collected...
November 30, 2016: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/27894209/the-prevalence-and-risk-indicators-of-symptoms-of-common-mental-disorders-among-current-and-former-dutch-elite-athletes
#4
Vincent Gouttebarge, Ruud Jonkers, Maarten Moen, Evert Verhagen, Paul Wylleman, Gino Kerkhoffs
The aim of the study was to determine the prevalence and comorbidity of symptoms of common mental disorders (distress, anxiety/depression, sleep disturbance, eating disorders, adverse alcohol use) among current and former Dutch elite athletes, and to explore the inference between potential risk indicators (severe injury, surgery, life events, sport career dissatisfaction, social support) and the outcomes measures under investigation. Cross-sectional analyses were conducted on baseline questionnaires from an ongoing prospective cohort study among 203 current and 282 former elite Dutch athletes (response rate: 28% among current athletes and 95% among former athletes)...
November 29, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/27891714/altered-serum-level-of-matrix-metalloproteinase-9-and-its-association-with-decision-making-in-eating-disorders
#5
Junko Matsumoto, Yoshiyuki Hirano, Kenji Hashimoto, Tamaki Ishima, Nobuhisa Kanahara, Tomihisa Niitsu, Akihiro Shiina, Tasuku Hashimoto, Yasunori Sato, Koutaro Yokote, Shunichi Murano, Hiroshi Kimura, Yutaka Hosoda, Eiji Shimizu, Masaomi Iyo, Michiko Nakazato
AIMS: The aims of this study were to determine whether the serum levels of precursor brain-derived neurotrophic factor (proBDNF), mature BDNF (mBDNF), and matrix metalloproteinase-9 (MMP-9) are altered in patients with eating disorders (EDs) including anorexia nervosa (AN) and bulimia nervosa (BN), and to explore whether those levels are associated with decision-making abilities. METHODS: Nineteen women with AN, 28 women with BN, and 22 age-matched healthy women (HC) were enrolled in the current study...
November 28, 2016: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/27891104/hoarding-symptoms-are-not-exclusive-to-hoarders
#6
Caterina Novara, Gioia Bottesi, Stella Dorz, Ezio Sanavio
Hoarding disorder (HD) was originally conceptualized as a subcategory of obsessive compulsive disorder (OCD), and numerous studies have in fact focused exclusively on investigating the comorbidity between OCD and HD. Hoarding behavior can nevertheless also be found in other clinical populations and in particular in patients with eating disorders (ED), anxiety disorders (AD), major depression (MD), and psychotic disorders (PD). The current study was carried out with the aim of investigating, using a validated instrument such as the Saving Inventory-Revised (SI-R), the presence of HD symptoms in patients diagnosed with ED, AD, MD, and PD...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27885066/effects-in-dogs-with-behavioural-disorders-of-a-commercial-nutraceutical-diet-on-stress-and-neuroendocrine-parameters
#7
S Sechi, A Di Cerbo, S Canello, G Guidetti, F Chiavolelli, F Fiore, R Cocco
The well-being of dogs can be affected by changes in human lifestyle, eating habits and increased stressors that lead to behavioural disorders including fear, hyperactivity and anxiety, followed by negative affective moods and poor welfare. This randomised, controlled clinical evaluation involved 69 dogs, 38 males and 31 females, of different breeds, with behavioural disorders related to anxiety and chronic stress. They were fed a control diet or a nutraceutical diet (ND group) for 45 days. Neuroendocrine (serotonin, dopamine, β-endorphins, noradrenaline and cortisol) and stress (derivatives of reactive oxygen metabolites (dROMs) and biological antioxidant potential (BAP)) parameters related to behavioural disorders were evaluated at the beginning and end of the study period...
November 24, 2016: Veterinary Record
https://www.readbyqxmd.com/read/27884425/the-eating-disorder-associated-hdac4-a778t-mutation-alters-feeding-behaviors-in-female-mice
#8
Michael Lutter, Michael Z Khan, Kenji Satio, Kevin C Davis, Ian J Kidder, Latisha McDaniel, Benjamin W Darbro, Andrew A Pieper, Huxing Cui
BACKGROUND: While eating disorders (EDs) are thought to result from a combination of environmental and psychological stressors superimposed on genetic vulnerability, the neurobiological basis of EDs remains incompletely understood. We recently reported that a rare missense mutation in the gene for the transcriptional repressor histone deacetylase 4 (HDAC4) is associated with the risk of developing an ED in humans. METHODS: To understand the biological consequences of this missense mutation, we created transgenic mice carrying this mutation by introducing the alanine to threonine mutation at position 778 of mouse Hdac4 (corresponding to position 786 of the human protein)...
October 13, 2016: Biological Psychiatry
https://www.readbyqxmd.com/read/27878933/psychiatric-disorders-during-early-adulthood-in-those-with-childhood-onset-type-1-diabetes-rates-and-clinical-risk-factors-from-population-based-follow-up
#9
M N Cooper, A Lin, G A Alvares, N H de Klerk, T W Jones, E A Davis
AIM: To determine the incidence of and risk factors for psychiatric disorders in early adulthood in patients with childhood onset type 1 diabetes (T1D). METHODS: In this retrospective-cohort study, we identified a population-based childhood onset T1D cohort and an age and sex matched (5:1) non-diabetic comparison cohort. Data linkage was used to access inpatient hospitalization data, mental health support service data, and mortality data to follow-up both cohorts into early adulthood...
November 23, 2016: Pediatric Diabetes
https://www.readbyqxmd.com/read/27877043/polycystic-ovary-syndrome-and-mental-disorders-a-systematic-review-and-exploratory-meta-analysis
#10
REVIEW
Sergio Luís Blay, João Vicente Augusto Aguiar, Ives Cavalcante Passos
BACKGROUND: The association between depression, anxiety, and polycystic ovary syndrome (PCOS) is still unclear. Therefore, a systematic review and meta-analysis was conducted to assess the rates of comorbid psychiatric disorders among women with PCOS compared to women without it. METHODS: PubMed/MEDLINE, Embase, PsycINFO, and Web of Science databases were searched from inception to November 27, 2015. Studies were eligible for inclusion if they were original reports in which the rates of mood (bipolar disorder, dysthymia, or major depressive disorder), obsessive-compulsive spectrum disorders, trauma- and stressor-related disorders, anxiety disorders or psychotic disorders, somatic symptom and related disorders, or eating disorders had been investigated among women with an established diagnosis of PCOS and compared with women without PCOS...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27862148/application-of-structural-equation-mixture-modeling-to-characterize-the-latent-structure-of-eating-pathology
#11
Kelsie T Forbush, Jennifer E Wildes
OBJECTIVE: Several theoretical models describe the structure of eating disorders (EDs), and a burgeoning empirical literature has sought to identify whether eating pathology is conceptualized best as categorical (presence or absence of disorder), dimensional (continuous), or a hybrid of categories and dimensions. METHODS: This study used structural equation mixture modeling (SEMM) to identify the latent structure of EDs. Items from the Eating Pathology Symptoms Inventory (EPSI) were administered to individuals with EDs (N = 344)...
November 12, 2016: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/27856605/medically-hospitalized-patients-with-eating-disorders-and-somatoform-disorders-in-pediatrics-what-are-their-similarities-and-differences-and-how-can-we-improve-their-care
#12
Patricia Ibeziako, Jennifer M Rohan, Simona Bujoreanu, Christine Choi, Meghan Hanrahan, Melissa Freizinger
OBJECTIVES: The purpose of the current study is to describe the demographic and clinical characteristics and health care use of medically hospitalized patients with eating disorders (ED) and somatoform disorders (SFD) in a pediatric setting and to use the findings to explore opportunities for improved care. METHODS: Retrospective chart reviews of 125 patients with SFD and 125 patients with ED (N = 250) seen at a tertiary pediatric facility over a 12- and 19-month period, respectively...
December 2016: Hospital Pediatrics
https://www.readbyqxmd.com/read/27855559/psychiatric-disorders-and-personality-styles-in-mothers-of-female-adolescent-patients-with-eating-disorders
#13
Silke Rost, Viola Kappel, Harriet Salbach, Nora Schneider, Ernst Pfeiffer, Ulrike Lehmkuhl, Sibylle Winter, Lea Sarrar
OBJECTIVE: To provide further insight into the presently poorly understood role of familial psychopathology in the development of eating disorders (ED). METHOD: The present study assesses psychiatric and personality disorders listed on Axis I and II of the DSM-IV in 27 mothers of adolescent patients with anorexia (AN mothers) and 14 bulimia nervosa (BN mothers) as well as 22 mentally healthy girls (CG mothers) on a categorical level. Furthermore, we conducted a dimensional diagnostic regarding personality styles and personality traits...
November 18, 2016: Zeitschrift Für Kinder- und Jugendpsychiatrie und Psychotherapie
https://www.readbyqxmd.com/read/27852337/eating-problems-in-adolescents-and-youths-explanatory-variables
#14
Carmen Maganto, Maite Garaigordobil, Lorea Kortabarria
This study had the following goals: (1) to analyze the differences between participants with and without risk of eating disorders (ED) in self-esteem, happiness, depression, anxiety, anger, and psychological variables related to ED; (2) to determine possible differences in the group at risk of ED on these variables as a function of sex; and (3) to determine which variables explain the risk of ED. Eight assessment instruments were administered to 1.075 participants (74.6% without risk of ED and 25.4% at risk)...
November 17, 2016: Spanish Journal of Psychology
https://www.readbyqxmd.com/read/27849376/clomiphene-citrate-in-the-treatment-of-idiopathic-or-functional-hypogonadotropic-hypogonadism-in-men-a-case-series-and-review-of-the-literature
#15
Yair Liel
OBJECTIVE: Late onset hypogonadotropic hypogonadism (LOH) is a complex, heterogeneous entity. Whenever treatment is indicated, the endocrine literature has recommend testosterone replacement. We present our experience with clomiphene citrate (CC) treatment in patients with LOH and a review of the literature. DESIGN: A retrospective case series. PATIENTS AND MEASUREMENTS: Eighteen male patients with hypogonadotropic hypogonadism, roughly according to the EMAS criteria for LOH, attended at an academic hospital outpatient clinic...
November 16, 2016: Endocrine Practice
https://www.readbyqxmd.com/read/27836626/stress-induced-eating-in-women-with-binge-eating-disorder-and-obesity
#16
Rebecca R Klatzkin, Sierra Gaffney, Kathryn Cyrus, Elizabeth Bigus, Kimberly A Brownley
The purpose of the current study was to investigate stress-induced eating in women with binge-eating disorder (BED) and obesity. Three groups of women [obese with BED (n=9); obese non-BED (n=11); and normal weight (NW) non-BED (n=12)], rated their levels of hunger and psychological distress before and after completing the Trier Social Stress Test, followed by food anticipation and then consumption of their preferred snack food. We differentiated between the motivational and hedonic components of eating by measuring the amount of food participants poured into a serving bowl compared to the amount consumed...
November 9, 2016: Biological Psychology
https://www.readbyqxmd.com/read/27830582/exposure-with-response-prevention-erp-for-body-dissatisfaction-in-a-group-therapy-format-an-exploratory-study
#17
Brad A Mac Neil, Pauline Leung, Vanessa Montemarano
PURPOSE: The aim of this exploratory study was to examine patient satisfaction and outcomes from exposure with response prevention (ERP) delivered in a group therapy format. The group was aimed at addressing eating disorder symptoms associated with body dissatisfaction in the later stages of outpatient treatment. METHODS: 33 adults with a DSM-5 diagnosis of an eating disorder participated in the ERP group. Participants completed pre- and post-ERP group measures of depression, anxiety, self-evaluation based on body image, restraint, eating concern, weight concern, shape concern, upward and downward appearance comparisons, and patient satisfaction...
November 9, 2016: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/27824643/clinical-psychological-and-physiological-correlates-of-patients-who-defecate-after-meal
#18
Michel Bouchoucha, Ghislain Devroede, Florence Mary, Cyriaque Bon, Gheorges Airinei, Bakhtiar Bejou, Robert Benamouzig
BACKGROUND AND AIMS: Food is the most important synchronizer of gastrointestinal motility and secretion. Many patients with functional bowel or anorectal disorders complain of fecal urge and stool output after eating. PATIENTS AND METHODS: In this prospective observational study, 408 consecutive outpatients with functional bowel and/or anorectal disorders (74% female, 50.2±15.6 years, 24.8±5.0 kg/m²) filled Rome III questionnaires. Depression and anxiety scores, a physiological evaluation (total and segmental colonic transit time, colonic transit response to eating using a standard 1000 kcal test meal, and anorectal manometry), were measured...
November 7, 2016: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27819466/the-structure-of-psychopathology-in-adolescence-and-its-common-personality-and-cognitive-correlates
#19
Natalie Castellanos-Ryan, Frederic N Brière, Maeve O'Leary-Barrett, Tobias Banaschewski, Arun Bokde, Uli Bromberg, Christian Büchel, Herta Flor, Vincent Frouin, Juergen Gallinat, Hugh Garavan, Jean-Luc Martinot, Frauke Nees, Tomas Paus, Zdenka Pausova, Marcella Rietschel, Michael N Smolka, Trevor W Robbins, Robert Whelan, Gunter Schumann, Patricia Conrod
The traditional view that mental disorders are distinct, categorical disorders has been challenged by evidence that disorders are highly comorbid and exist on a continuum (e.g., Caspi et al., 2014; Tackett et al., 2013). The first objective of this study was to use structural equation modeling to model the structure of psychopathology in an adolescent community-based sample (N = 2,144) including conduct disorder, attention-deficit/hyperactivity disorder (ADHD), oppositional-defiant disorder (ODD), obsessive-compulsive disorder, eating disorders, substance use, anxiety, depression, phobias, and other emotional symptoms, assessed at 16 years...
November 2016: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/27809925/guided-self-help-interventions-for-mental-health-disorders-in-children-with-neurological-conditions-study-protocol-for-a-pilot-randomised-controlled-trial
#20
Sophie Bennett, Isobel Heyman, Anna Coughtrey, Jess Simmonds, Sophia Varadkar, Terence Stephenson, Margaret DeJong, Roz Shafran
BACKGROUND: Rates of mental health disorders are significantly greater in children with physical illnesses than in physically well children. Children with neurological conditions, such as epilepsy, are known to have particularly high rates of mental health disorders. Despite this, mental health problems in children with neurological conditions have remained under-recognised and under-treated in clinical settings. Evidence-based guided self-help interventions are efficacious in reducing symptoms of mental health disorders in children, but their efficacy in reducing symptoms of common mental health disorders in children with neurological conditions has not been investigated...
November 4, 2016: Trials
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