keyword
https://read.qxmd.com/read/38508791/improvement-of-postural-control-in-the-frail-older-adults-through-foot-care-a-pre-and-post-intervention-study
#21
JOURNAL ARTICLE
Tomoko Yamashita, Kazuhiko Yamashita, Mitsuru Sato, Shingo Ata
Frailty in older adults often leads to foot issues, increasing fall-related fracture risk. Mechanoreceptors, the pressure receptors in the foot sole, are pivotal for postural control. Foot problems can impair mechanoreceptor function, compromising balance. This study aimed to examine the effect of foot care on postural control in frail older adults. Forty-eight participants underwent a five-month monthly foot care intervention. Measurements were taken before and after this intervention. Participants stood for 45 s in a static, open-eyed position on a stabilometer...
March 2024: Medical Engineering & Physics
https://read.qxmd.com/read/38508629/health-related-quality-of-life-after-12-months-post-discharge-in-patients-hospitalised-with-covid-19-related-severe-acute-respiratory-infection-sari-a-prospective-analysis-of-sf-36-data-and-correlation-with-retrospective-admission-data-on-age-disease-severity
#22
JOURNAL ARTICLE
Gavin Wright, Keerthi Senthil, Amir Zadeh-Kochek, Jonathan Heung-San Au, Jufen Zhang, Jiawei Huang, Ravi Saripalli, Mohiuddin Khan, Omar Ghauri, San Kim, Zakiuddin Mohammed, Carol Alves, Gouri Koduri
UNLABELLED: Long-term outcome and 'health-related quality of life' (HRQoL) following hospitalisation for COVID-19-related severe acute respiratory infection (SARI) is limited. OBJECTIVE: To assess the impact of HRQoL in patients hospitalised with COVID-19-related SARI at 1 year post discharge, focusing on the potential impact of age, frailty, and disease severity. METHOD: Routinely collected outcome data on 1207 patients admitted with confirmed COVID-19 related SARI across all three secondary care sites in our NHS trust over 3 months were assessed in this retrospective cohort study...
March 20, 2024: BMJ Open
https://read.qxmd.com/read/38507855/joint-trajectories-of-physical-frailty-and-social-frailty-and-associations-with-adverse-outcomes-a-prospective-cohort-study
#23
JOURNAL ARTICLE
Qinqin Liu, Yuli Huang, Shuai Gao, Binlin Wang, Yanyan Li, Huaxin Si, Wendie Zhou, Jiaqi Yu, Hejing Chen, Cuili Wang
BACKGROUND: We examined joint trajectories of physical frailty and social frailty as well as their associations with adverse outcomes. METHODS: We conducted a prospective cohort study by using five waves of national data from China Health and Retirement Longitudinal Study (CHARLS 2011-2020), involving 4531 participants aged ≥60 years. We identified 4-year trajectories at three examinations from 2011 to 2015 using parallel process latent class growth analysis...
March 5, 2024: Archives of Gerontology and Geriatrics
https://read.qxmd.com/read/38507650/multi-trajectories-of-symptoms-and-their-associations-with-unplanned-30-day-hospital-readmission-among-patients-with-heart-failure-a-longitudinal-study
#24
JOURNAL ARTICLE
Qingyun Lv, Xiaonan Zhang, Yaqi Wang, Xueying Xu, Yuan He, Jingwen Liu, Hairong Chang, Xiaoying Zang, Yue Zhao
AIMS: This study aimed to uncover hidden patterns and predictors of symptom multi-trajectories within 30 days after discharge in patients with heart failure and assess the risk of unplanned 30-day hospital readmission in different patterns. METHODS AND RESULTS: The study was conducted from September 2022 to September 2023 in four third-class hospitals in Tianjin, China. A total of 301 patients with heart failure were enrolled in the cohort, and 248 patients completed a 30-day follow-up after discharge...
March 20, 2024: European Journal of Cardiovascular Nursing
https://read.qxmd.com/read/38507270/force-sensing-treadmill-gait-analysis-system-can-detect-gait-abnormalities-in-haemophilia-patients-without-arthropathy
#25
JOURNAL ARTICLE
Yuya Mawarikado, Asuka Sakata, Yusuke Inagaki, Suguru Harada, Kohei Tatsumi, Naoki Matsumoto, Kenichi Ogiwara, Koji Yada, Yasushi Yoshimura, Akira Kido, Yasuhito Tanaka, Midori Shima, Keiji Nogami
BACKGROUND: Joint damage in patients with haemophilia (PwH) is commonly assessed by imaging, but few reports have described how structural changes in joints, for example, haemophilic arthropathy (HA)-affect gait ability. OBJECTIVES: We evaluated gait function among PwH with HA, PwH without HA, and people without haemophilia (non-PwH) using a Zebris FDM-T treadmill (FDM-T), an easy-to-use gait assessment instrument with a force sensor matrix. METHODS: The following gait parameters were collected: centre of pressure trajectory intersection (COPi) anterior/posterior variability, COPi lateral variability, COPi anterior/posterior symmetry, COPi lateral symmetry, single-limb support line (SLSL) length, and SLSL variability...
March 20, 2024: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://read.qxmd.com/read/38505789/an-open-label-feasibility-study-of-a-nutrition-and-exercise-app-based-solution-in-cirrhosis
#26
JOURNAL ARTICLE
Kathleen P Ismond, Christofer Cruz, Ana Teresa Limon-Miro, Gavin Low, Carla M Prado, John C Spence, Maitreyi Raman, Margaret L McNeely, Puneeta Tandon
BACKGROUND: Nutrition and exercise are the mainstay of therapy for the prevention and treatment of frailty in cirrhosis. This pilot study assessed feasibility of the online delivery of an app-based semi-supervised nutrition and exercise intervention in this population. METHODS: The 11-week pilot recruited adults with cirrhosis who owned internet-connected devices. Patients were encouraged to participate in exercise sessions 3× per week including a combination of online group exercise (weekly) and home-based follow-along exercise (biweekly)...
February 2024: Canadian liver journal
https://read.qxmd.com/read/38504183/post-discharge-nutritional-management-for-patients-with-coronary-heart-disease-and-frailty-a-qualitative-study
#27
JOURNAL ARTICLE
Yifei Yang, Jing Gong, Binxu Yang, Chan Chen, Xintong Deng, Kejun Chen, Yingying Zhao, Xusihong Cai, Jingjing Li, Jing Zhou
BACKGROUND: Frail elderly patients experience physiological function and reserve depletion, leading to imbalances in their internal environment, which increases the risk of coronary heart disease recurrence and malnutrition. However, the majority of these patients, who primarily have a low level of education and lack self-management skills, face difficulties actively dealing with obstacles during the transition period after their discharge from hospitalization. Therefore, it is necessary to understand and discuss in depth the nutrition management experience of discharged elderly patients with coronary heart disease and frailty (ages 65-80 years old) and to analyze the promoting and hindering factors that affect scientific diet behavior during the discharge transition period...
March 19, 2024: BMC Geriatrics
https://read.qxmd.com/read/38504171/do-changes-in-the-frailty-score-differ-by-the-type-of-group-sports-and-exercises-participated-in-a-3-year-longitudinal-study
#28
JOURNAL ARTICLE
Taishi Tsuji, Satoru Kanamori, Ryota Watanabe, Meiko Yokoyama, Yasuhiro Miyaguni, Masashige Saito, Katsunori Kondo
BACKGROUND: Older adults who engage in group sports and exercises achieve greater health benefits than those who exercise by themselves. The benefits of group participation may vary depending on the type of sports/exercise they engage in. The present study aimed to identify the association between specific sports and exercise types performed in groups and evaluate the longitudinal changes in multidimensional frailty scores among community-dwelling older adults in Japan. METHODS: We used 3-year follow-up data from the Japan Gerontological Evaluation Study and analyzed 33,746 men and 36,799 women aged ≥ 65 years...
March 20, 2024: European Review of Aging and Physical Activity
https://read.qxmd.com/read/38501181/characteristics-according-to-frailty-status-among-older-korean-patients-with-hypertension
#29
JOURNAL ARTICLE
Jung-Yeon Choi, Hae-Young Lee, Ju-Hee Lee, Youjin Hong, Sue K Park, Dong Ryeol Ryu, Jang Hoon Lee, Seokjae Hwang, Kye Hun Kim, Sun Hwa Lee, Song-Yi Kim, Jae-Hyeong Park, Sang-Hyun Kim, Hack-Lyoung Kim, Jung Hyun Choi, Cheol-Ho Kim, Myeong-Chan Cho, Kwang-Il Kim
BACKGROUND: As the prevalence of hypertension increases with age and the proportion of the older population is also on the rise, research on the characteristics of older hypertensive patients and the importance of frailty is necessary. This study aimed to identify clinical characteristics of older hypertension in Korea and to investigate these characteristics based on frailty status. METHODS: The HOW to Optimize eLDerly systolic BP (HOWOLD-BP) is a prospective, multicenter, open-label, randomized clinical trial that aims to compare intensive (target systolic blood pressure [SBP] ≤ 130 mmHg) with standard (target SBP ≤ 140 mmHg) treatment to reduce cardiovascular events in older hypertensive Korean patients aged ≥ 65 years...
March 18, 2024: Journal of Korean Medical Science
https://read.qxmd.com/read/38500524/characterization-of-social-frailty-domains-and-related-adverse-health-outcomes-in-the-asia-pacific-a-systematic-literature-review
#30
JOURNAL ARTICLE
Tengku Aizan Hamid, Sarah Abdulkareem Salih, Siti Farra Zillah Abdullah, Rahimah Ibrahim, Aidalina Mahmud
BACKGROUND: Frailty is a significant healthcare challenge worldwide, increasing interest in developing more assessment tools covering for frailty. Recently, there has been a growing awareness of a correlation between social variables and frailty in older people. However, there is a lack of understanding of the social domains of frailty and the related adverse outcomes, particularly in the Asia-Pacific settings. This study aimed to characterize the social frailty domains and their health outcomes by overviewing the frailty screening tools in older people living in the Asia-Pacific region...
2024: PeerJ
https://read.qxmd.com/read/38500091/the-impact-of-residential-environment-on-older-people-s-capabilities-to-live-independently-a-survey-in-beijing
#31
JOURNAL ARTICLE
Mengyuan Chen, Gideon Bolt, Pieter Hooimeijer
BACKGROUND: Studies have shown how environmental factors influence older people's health and functional limitations, which are crucial for achieving healthy aging. However, such a healthy aging model has been criticized for defining health as an absence of disease, because chronic conditions cannot be reversed through medical treatments. In response to such critiques, this study refers to Huber's positive health definition, arguing that health should not be defined as the absence of disease but as the ability to adapt and self-manage in the face of social, physical, and emotional challenges...
March 18, 2024: BMC Public Health
https://read.qxmd.com/read/38498271/phosphate-is-associated-with-frailty-in-older-patients-with-chronic-kidney-disease-not-on-dialysis
#32
JOURNAL ARTICLE
Mariana P Veloso, Venceslau A Coelho, Nigar Sekercioglu, Rosa M A Moyses, Rosilene M Elias
PURPOSE: Frailty is common in older patients with chronic kidney disease (CKD) and has been considered an independent risk factor for adverse clinical outcomes in this population. CKD-associated mineral and bone metabolism (CKD-MBD) increases energy expenditure and causes malnutrition and inflammation leading to frailty. We investigated whether CKD-MBD markers and energy metabolism are associated with frailty in patients with advanced CKD on conservative management. METHODS: In this cross-sectional study, we investigated factors associated with frailty in a sample of 75 patients ≥ 65 years, with stage 4 or 5 CKD...
March 18, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38497389/low-triiodothyronine-syndrome-and-depression-a-cross-sectional-study-in-the-elderly-based-on-comprehensive-geriatric-assessment
#33
JOURNAL ARTICLE
Qian Xue, Yanru Ma, Xia Li, Lihua Deng, Jingtong Wang
INTRODUCTION: Thyroid diseases such as low triiodothyronine syndrome (LT3S) are more common in the elderly population. Comprehensive geriatric assessment (CGA) has been proposed as a supplementary tool for evaluating medical, functional, psychological, and frailty status and various geriatric syndromes. This study aimed to evaluate the impact of thyroid diseases on overall health status using a novel CGA strategy. MATERIAL AND METHODS: 477 patients were enrolled between January 2019 and December 2022...
2024: Endokrynologia Polska
https://read.qxmd.com/read/38495556/impact-of-physical-and-sexual-abuse-on-risk-of-hospitalisations-for-physical-and-mental-illnesses-insights-from-two-large-prospective-cohort-studies
#34
JOURNAL ARTICLE
Philipp Frank, G David Batty, Jaana Pentti, Markus Jokela, Jenni Ervasti, Andrew Steptoe, Glyn Lewis, Mika Kivimäki
BACKGROUND: Physical abuse can lead to severe health consequences that extend beyond immediate harm. We explored the associations of physical abuse experienced during childhood and adulthood with a wide range of adult health conditions requiring hospital treatment. METHODS: We utilised data from a sub-cohort of 157,366 UK Biobank participants (46.4% of the baseline population; age range 45-81; 89,101 women) and repeated analyses in an independent population of 85,929 adults from the Finnish Public Sector (FPS) study (age range 17-78; 68,544 women)...
May 2024: The Lancet regional health. Europe
https://read.qxmd.com/read/38493245/metabolomic-profiles-of-ovariectomized-mice-and-their-associations-with-body-composition-and-frailty-related-parameters-in-postmenopausal-women
#35
JOURNAL ARTICLE
S J Kim, Y Jo, S J Park, E Ji, J Y Lee, E Choi, J-Y Baek, I Y Jang, H-W Jung, K Kim, D Ryu, H J Yoo, B-J Kim
BACKGROUND: Menopause, a dramatical estrogen-deficient condition, is considered the most significant milestone in women's health. PURPOSE: To investigate the metabolite changes attributed to estrogen deficiency using random forest (RF)-based machine learning (ML) modeling strategy in ovariectomized (OVX) mice as well as determine the clinical relevance of selected metabolites in older women. METHODS AND RESULTS: Untargeted and targeted metabolomic analyses revealed that metabolites related to TCA cycle, sphingolipids, phospholipids, fatty acids, and amino acids, were significantly changed in the plasma and/or muscle of OVX mice...
March 17, 2024: Journal of Endocrinological Investigation
https://read.qxmd.com/read/38489994/the-predictive-value-of-masticatory-function-for-adverse-health-outcomes-in-older-adults-a-systematic-review
#36
REVIEW
Menke J de Smit, Willemke Nijholt, Mieke H Bakker, Anita Visser
Masticatory function is associated with a variety of health outcomes. The aim of this systematic review is to clarify the predictive value of masticatory function for adverse health outcomes, such as frailty, sarcopenia and malnutrition, in older adults. An online literature search covered articles published in English or Dutch in three databases (PubMed, Embase and CINAHL, last searched November 4th 2022). Inclusion criteria were: an observational study design, focus on adults aged ≥65 years and evaluation of the association between masticatory function and health outcomes...
March 14, 2024: Journal of Nutrition, Health & Aging
https://read.qxmd.com/read/38489867/growth-hormone-treatment-in-aged-patients-with-comorbidities-a-systematic-review
#37
REVIEW
Olivia Tausendfreund, Martin Bidlingmaier, Sebastian Martini, Katharina Müller, Michaela Rippl, Katharina Schilbach, Ralf Schmidmaier, Michael Drey
OBJECTIVE: Hormonal substitution with growth hormone in aged patients remains a debated research topic and is rarely initiated in clinical practice. This reluctance may originate from concerns about adverse effects and the uncritical use as an anti-aging agent. Nevertheless, beneficial effects for selected patients suffering from certain acute and chronic illnesses could justify its use at an advanced age. This systematic review analyzes randomized controlled studies of GH interventions in older patients with different comorbidities to assess both, beneficial and harmful effects...
March 9, 2024: Growth Hormone & IGF Research
https://read.qxmd.com/read/38488316/one-bite-sized-3d-printed-finger-foods-oriented-to-malnutrition-sarcopenia-and-frailty-prevention-in-the-older-people
#38
JOURNAL ARTICLE
Aušrinė Kurapkienė, Rimantė Vinauskienė, Ina Jasutienė, Gytė Damulevičienė, Jurgita Knašienė, Vita Lesauskaitė, Claire Sulmont-Rosse, Viktorija Eisinaitė, Daiva Leskauskaitė
BACKGROUND: In this study, innovative chocolate, citrus and mixture flavoured tofu-based nutritionally customized, dysphagia-oriented, comfortable-consumed, appetizing, one-bite sized finger foods, oriented to the malnutrition, sarcopenia, and frailty prevention in the older people were created by using 3D printing technology. Developed products were characterised by evaluating chemical composition, physical properties and performing sensory evaluation among geriatric clinic residents (≥60 years)...
March 15, 2024: Journal of the Science of Food and Agriculture
https://read.qxmd.com/read/38487922/restorative-effects-of-epicatechin-in-a-rodent-model-of-aging-induced-muscle-atrophy-underlying-mechanisms
#39
JOURNAL ARTICLE
Israel Ramirez-Sanchez, Viridiana Navarrete-Yañez, Lucia Ramirez, Leonor Galera, Enrique Mendez-Bolaina, Veronica Najera, Guillermo Ceballos, Francisco Villarreal
Sarcopenia is a progressive and generalized age-related skeletal muscle (SkM) disorder characterized by the accelerated loss of muscle mass (atrophy) and function. SkM atrophy is associated with increased incidence of falls, functional decline, frailty and mortality. In its early stage, SkM atrophy is associated with increased pro-inflammatory cytokine levels and proteasome-mediated protein degradation. These processes also link to the activation of atrophy associated factors and signaling pathways for which, there is a lack of approved pharmacotherapies...
March 15, 2024: Food & Function
https://read.qxmd.com/read/38485236/sarcopenia-as-the-mobility-phenotype-of-aging-clinical-implications
#40
JOURNAL ARTICLE
Sunghwan Ji, Hee-Won Jung, Ji Yeon Baek, Il-Young Jang, Eunju Lee
Sarcopenia, which is characterized by an age-related decline in muscle mass and function, poses significant challenges to geriatric care. Its definition has evolved from muscle-specific criteria to include muscle mass, muscle function, and physical performance, recognizing sarcopenia as a physical frailty. Sarcopenia is associated with adverse outcomes, including mortality, falls, fractures, cognitive decline, and admission to long-term care facilities. Neuromechanical factors, protein-energy balance, and muscle protein synthesis-breakdown mechanisms contribute to its pathophysiology...
February 2024: Journal of Bone Metabolism
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