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Physical frailty

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https://www.readbyqxmd.com/read/28543956/influence-of-frailty-on-the-quality-of-life-patients-qualified-for-pacemaker-implantation
#1
Agnieszka Mlynarska, Rafal Mlynarski, Krzysztof S Golba
AIMS AND OBJECTIVES: An important question is whether frailty syndrome affects the assessment of quality of life or whether frailty syndrome may reduce the benefits of a cardiac pacemaker implantation. BACKGROUND: Frailty syndrome is known risk factor for quality of life evaluation after selected cardiology invasive procedures. DESIGN: The study was designed as single center prospective study. METHODS: The study included 171 patients aged ≥ 60 years who were qualified for pacemaker implantation...
May 25, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28542531/new-diagnostic-index-for-sarcopenia-in-patients-with-cardiovascular-diseases
#2
Haruhito Harada, Hisashi Kai, Rei Shibata, Hiroshi Niiyama, Yasuhiro Nishiyama, Toyoaki Murohara, Noriko Yoshida, Atsushi Katoh, Hisao Ikeda
BACKGROUND: Sarcopenia is an aging and disease-related syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength, with the risk of frailty and poor quality of life. Sarcopenia is diagnosed by a decrease in skeletal muscle index (SMI) and reduction of either handgrip strength or gait speed. However, measurement of SMI is difficult for general physicians because it requires special equipment for bioelectrical impedance assay or dual-energy X-ray absorptiometry...
2017: PloS One
https://www.readbyqxmd.com/read/28541397/prevalence-and-co-occurrence-of-geriatric-syndromes-in-people-aged-75-years-and-older-in-france-results-from-the-bordeaux-three-city-study
#3
Maturin Tabue-Teguo, Leslie Grasset, José Alberto Avila-Funes, Robin Genuer, Cecile Proust-Lima, Karine Péres, Catherine Féart, Hélène Amieva, Magali González-Colaço Harmand, Catherine Helmer, Nathalie Salles, Muriel Rainfray, Jean François Dartigues
Background: Geriatric syndromes (GSs) are often the result of cumulative insults to multiple organ systems and are considered common in older adults. However, their frequency and co-occurrence are not well known in the elderly population. This study aimed to determine the prevalence of several GSs and to analyze the co-occurrence of these syndromes in a general population of elderly individuals. Methods: A cross-sectional analysis of 630 adults aged 75 years or older participating in the 10-year follow-up of the Bordeaux sample of the French Three-City Study was conducted...
May 24, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28540538/impact-of-a-community-based-frailty-intervention-among-middle-aged-and-older-prefrail-and-frail-homeless-women-a-pilot-randomized-controlled-trial
#4
Benissa E Salem, Jennifer Ma-Pham, Stephanie Chen, Mary-Lynn Brecht, Anna Liza Antonio, Masha Ames
Interventions are needed to address frailty and other behaviors (e.g., drug and alcohol use) among prefrail and frail homeless women (P/FHW). The purpose of this pilot randomized controlled trial (RCT) was to compare the efficacy of a Frailty Intervention (FI) versus a Health Promotion (HP) program among P/FHW (N = 32). Structured instruments assessed sociodemographics, individual, situational, health-related, and behavioral factors. While program differences were not statistically significant with the main outcome variables, medium-to-large effect sizes were found in favor of the HP program as it relates to physical and overall frailty, as well as, any drug use, alcohol use, and drug dependency...
May 24, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/28539130/the-relation-of-education-occupation-and-cognitive-activity-to-cognitive-status-in-old-age-the-role-of-physical-frailty
#5
Andreas Ihle, Élvio R Gouveia, Bruna R Gouveia, Duarte L Freitas, Jefferson Jurema, Angenay P Odim, Matthias Kliegel
BACKGROUND: It remains unclear so far whether the role of cognitive reserve may differ between physically frail compared to less frail individuals. Therefore, the present study set out to investigate the relation of key markers of cognitive reserve to cognitive status in old age and its interplay with physical frailty in a large sample of older adults. METHODS: We assessed Mini-Mental State Examination (MMSE) in 701 older adults. We measured grip strength as indicator of physical frailty and interviewed individuals on their education, past occupation, and cognitive leisure activity...
May 25, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28537326/cognitive-frailty-in-italian-community-dwelling-older-adults-prevalence-rate-and-its-association-with-disability
#6
M Roppolo, A Mulasso, E Rabaglietti
Cognitive frailty is the simultaneous clinical manifestation of both physical frailty and cognitive impairment. This paper aimed to propose and test an operational definition of cognitive frailty. The following specific aims were pursued: (i) to rate the prevalence of cognitive frailty; (ii) to evaluate differences in cognitive functioning among robust, pre-frail, and frail individuals; (iii) to examine the association of cognitive frailty with disability, in a sample of Italian community-dwelling older adults...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28532299/role-of-objectively-measured-sedentary-behaviour-in-physical-performance-frailty-and-mortality-among-older-adults-a-short-systematic-review
#7
Asier Mañas, Borja Del Pozo-Cruz, Francisco José García-García, Amelia Guadalupe-Grau, Ignacio Ara
Sedentary behaviour (SB) has recently emerged as an independent risk factor for different health outcomes. Older adults accumulate long time in SB. Understanding the role that SB plays on health is crucial for a successful aging. This short systematic review summarizes the current evidence related to the effects of objectively measured SB on frailty, physical performance and mortality in adults ≥60 years old. The literature search produced 271 records for physical performance (n = 119), frailty (n = 31), and mortality (n = 121)...
May 22, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28527727/patient-outcomes-following-lower-leg-major-amputations-for-peripheral-arterial-disease-a-series-review
#8
Susan Monaro, Sandra West, Janice Gullick
INTRODUCTION: Despite improvements in revascularization, major amputation remains a significant part of the case-mix in vascular surgical units. These patients tend to be elderly with complex pathology, resulting in poor outcomes and longer lengths of stay (LOS). AIM: This series review provides a description of the patient complexities and outcomes in an Australian cohort undergoing major lower limb amputation for peripheral arterial disease. METHOD: Medical records coded for major amputation between July 2012 and June 2013 in an Australian government funded, tertiary hospital were retrospectively reviewed and descriptively analyzed...
June 2017: Journal of Vascular Nursing: Official Publication of the Society for Peripheral Vascular Nursing
https://www.readbyqxmd.com/read/28526765/factors-associated-with-ischemic-stroke-survival-and-recovery-in-older-adults
#9
Divya Thekkethala Winovich, William T Longstreth, Alice M Arnold, Ravi Varadhan, Adina Zeki Al Hazzouri, Mary Cushman, Anne B Newman, Michelle C Odden
BACKGROUND AND PURPOSE: Little is known about factors that predispose older adults to poor recovery after a stroke. In this study, we sought to evaluate prestroke measures of frailty and related factors as markers of vulnerability to poor outcomes after ischemic stroke. METHODS: In participants aged 65 to 99 years with incident ischemic strokes from the Cardiovascular Health Study, we evaluated the association of several risk factors (frailty, frailty components, C-reactive protein, interleukin-6, and cystatin C) assessed before stroke with stroke outcomes of survival, cognitive decline (≥5 points on Modified Mini-Mental State Examination), and activities of daily living decline (increase in limitations)...
May 19, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28525586/prevalence-and-correlates-of-frailty-among-community-dwelling-chinese-older-adults-the-china-health-and-retirement-longitudinal-study
#10
Chenkai Wu, Ellen Smit, Qian-Li Xue, Michelle C Odden
Background.: Frailty is an age-related clinical syndrome of decreased resilience to stressors and is associated with numerous adverse outcomes. Although there is preponderance of literature on frailty in developed countries, limited investigations have been conducted in less developed regions including China-a country that has the world's largest aging population. We examined frailty prevalence in China by socio-demographics and geographic region, and investigated correlates of frailty...
May 19, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28514618/aerobic-or-resistance-exercise-or-both-in-dieting-obese-older-adults
#11
RANDOMIZED CONTROLLED TRIAL
Dennis T Villareal, Lina Aguirre, A Burke Gurney, Debra L Waters, David R Sinacore, Elizabeth Colombo, Reina Armamento-Villareal, Clifford Qualls
BACKGROUND: Obesity causes frailty in older adults; however, weight loss might accelerate age-related loss of muscle and bone mass and resultant sarcopenia and osteopenia. METHODS: In this clinical trial involving 160 obese older adults, we evaluated the effectiveness of several exercise modes in reversing frailty and preventing reduction in muscle and bone mass induced by weight loss. Participants were randomly assigned to a weight-management program plus one of three exercise programs - aerobic training, resistance training, or combined aerobic and resistance training - or to a control group (no weight-management or exercise program)...
May 18, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28505291/comparison-of-the-simplified-swhi-and-the-standard-chs-frailty-phenotypes-for-prediction-of-mortality-incident-falls-and-hip-fractures-in-older-women
#12
Oleg Zaslavsky, Shira Zelber-Sagi, Andrea Z LaCroix, Robert L Brunner, Robert B Wallace, Barbara B Cochrane, Nancy F Woods
Background: We compared the simplified Women's Health Initiative (sWHI) and the standard Cardiovascular Health Study (CHS) frailty phenotypes in predicting falls, hip fracture, and death in older women. Methods: Participants are from the WHI Clinical Trial. CHS frailty criteria included weight loss, exhaustion, weakness, slowness, and low physical activity. The sWHI frailty score used two items from the RAND-36 physical function and vitality subscales, one item from the WHI physical activity scale plus the CHS weight loss criteria...
May 13, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28503567/cognitive-impairment-in-chronic-kidney-disease-vascular-milieu-and-the-potential-therapeutic-role-of-exercise
#13
REVIEW
Ulf G Bronas, Houry Puzantian, Mary Hannan
Chronic kidney disease (CKD) is considered a model of accelerated aging. More specifically, CKD leads to reduced physical functioning and increased frailty, increased vascular dysfunction, vascular calcification and arterial stiffness, high levels of systemic inflammation, and oxidative stress, as well as increased cognitive impairment. Increasing evidence suggests that the cognitive impairment associated with CKD may be related to cerebral small vessel disease and overall impairment in white matter integrity...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28501417/prevalence-of-frailty-assessed-by-fried-and-kihon-checklist-indexes-in-a-prospective-cohort-study-design-and-demographics-of-the-kyoto-kameoka-longitudinal-study
#14
Yosuke Yamada, Hinako Nanri, Yuya Watanabe, Tsukasa Yoshida, Keiichi Yokoyama, Aya Itoi, Heiwa Date, Miwa Yamaguchi, Motoko Miyake, Emi Yamagata, Hajime Tamiya, Miho Nishimura, Mami Fujibayashi, Naoyuki Ebine, Mitsuyoshi Yoshida, Takeshi Kikutani, Eiichi Yoshimura, Kazuko Ishikawa-Takata, Minoru Yamada, Tomoki Nakaya, Yasuko Yoshinaka, Yoshinori Fujiwara, Hidenori Arai, Misaka Kimura
OBJECTIVE: The Kyoto-Kameoka Study was launched in 2011-2012 to identify the associations among food intake, nutritional status, physical activity, oral function, quality of life or social capital, the use of long-term care insurance (LTCI) system, and healthy lifespan in community-dwelling older people as a part of the World Health Organization Safe Community program. DESIGN: A prospective cohort study, reporting baseline demographics (cross-sectional data). SETTING AND PARTICIPANTS: We conducted 2 mailed self-administered questionnaire surveys; one is a complete population survey with a comprehensive survey of needs in the sphere of daily life (NSDL) that included 2 different frailty indexes, the Kihon Checklist (KCL) and the Fried phenotype, socioeconomic status, general and psychological health, and social relationships; followed by the more detailed Health and Nutrition Survey...
May 11, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28499379/diet-with-a-combination-of-high-protein-and-high-total-antioxidant-capacity-is-strongly-associated-with-low-prevalence-of-frailty-among-old-japanese-women-a-multicenter-cross-sectional-study
#15
Satomi Kobayashi, Hitomi Suga, Satoshi Sasaki
BACKGROUND: The intake of protein and antioxidants has been inversely associated with frailty, individually. However, to our knowledge, no study has evaluated these associations in considering antioxidants or protein intakes as respective confounders. Further, the cooperative effect of dietary protein and antioxidants on frailty has not been investigated. Therefore, we examined the association of high protein and high dietary total antioxidant capacity (TAC) with frailty under the adjustment for dietary TAC or protein intake, respectively...
May 12, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28498173/the-meaning-of-confidence-for-older-people-living-with-frailty-a-qualitative-systematic-review
#16
Frazer Underwood, Lisa Burrows, Rod Gegg, Jos M Latour, Bridie Kent
BACKGROUND: In many countries, the oldest old (those aged 85 years and older) are now the fastest growing proportion of the total population. This oldest population will increasingly be living with the clinical condition of frailty. Frailty syndromes negatively impact on the person as they do the healthcare systems supporting them. Within healthcare literature "loss of confidence" is occasionally connected to older people living with frailty, but ambiguously described. Understanding the concept of confidence within the context of frailty could inform interventions to meet this growing challenge...
May 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28496545/c-reactive-protein-and-frailty-in-the-elderly-a-literature-review
#17
REVIEW
Dimitrios Velissaris, Nikolaos Pantzaris, Ioanna Koniari, Nikolaos Koutsogiannis, Vasilios Karamouzos, Ioanna Kotroni, Anastasia Skroumpelou, John Ellul
Chronic inflammation is a well-established background process in many age-related diseases. Many recent studies investigate the use of various inflammatory biomarkers such as C-reactive protein (CRP), interleukin-6, and interleukin-1 as predictors of physical and cognitive performance among elders. The phenotype of frailty has also been associated with underlying inflammatory mechanisms. The aim of this article was to review the literature referring to the correlation of CRP serum levels and frailty in older individuals...
June 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28490866/nonpharmacological-interventions-to-treat-physical-frailty-and-sarcopenia-in-older-patients-a-systematic-overview-the-senator-project-ontop-series
#18
REVIEW
Isabel Lozano-Montoya, Andrea Correa-Pérez, Iosief Abraha, Roy L Soiza, Antonio Cherubini, Denis O'Mahony, Alfonso J Cruz-Jentoft
BACKGROUND: Physical frailty (PF) and sarcopenia are predictors of negative health outcomes such as falls, disability, hospitalization, and death. Some systematic reviews (SRs) have been published on different nonpharmacological treatments of frailty and sarcopenia using heterogeneous definitions of them. OBJECTIVE: To critically appraise the evidence from SRs of the primary studies on nonpharmacological interventions to treat PF (defined by Fried's frailty phenotype) and sarcopenia (defined by the EWGSOP) in older patients...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28483768/serious-adverse-events-and-the-risk-of-stroke-in-patients-with-rheumatoid-arthritis-results-from-the-german-rabbit-cohort
#19
Y Meissner, A Richter, B Manger, H P Tony, E Wilden, J Listing, A Zink, A Strangfeld
OBJECTIVE: In the general population, the incidence of stroke is increased following other serious events and hospitalisation. We investigated the impact of serious adverse events on the risk of stroke in patients with rheumatoid arthritis (RA), taking risk factors and treatment into account. METHODS: Using data of the German biologics register RABBIT (Rheumatoid Arthritis: Observation of Biologic Therapy) with 12354 patients with RA, incidence rates (IRs) and risk factors for stroke were investigated using multi-state and Cox proportional hazard models...
May 8, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28475664/dynamical-resilience-indicators-in-time-series-of-self-rated-health-correspond-to-frailty-levels-in-older-adults
#20
Sanne M W Gijzel, Ingrid A van de Leemput, Marten Scheffer, Mattia Roppolo, Marcel G M Olde Rikkert, René J F Melis
Background: We currently still lack valid methods to dynamically measure resilience for stressors before the appearance of adverse health outcomes that hamper well-being. Quantifying an older adult's resilience in an early stage would aid complex decision-making in health care. Translating complex dynamical systems theory to humans, we hypothesized that three dynamical indicators of resilience (variance, temporal autocorrelation, and cross-correlation) in time series of self-rated physical, mental, and social health were associated with frailty levels in older adults...
May 5, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
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