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https://www.readbyqxmd.com/read/27879449/ethnic-comparison-of-clinical-characteristics-and-ischemic-stroke-subtypes-among-young-adult-patients-with-stroke-in-hawaii
#1
Kazuma Nakagawa, Cherisse S Ito, Sage L King
BACKGROUND AND PURPOSE: Native Hawaiians and other Pacific Islanders (NHOPI) with ischemic stroke have younger age of stroke onset compared with whites. However, ethnic differences in stroke subtypes in this population have been inadequately studied. METHODS: Consecutive young adult patients (aged ≤55 years) who were hospitalized for ischemic stroke between 2006 and 2012 at a tertiary center in Honolulu were studied. Clinical characteristics and stroke subtypes based on pathophysiological TOAST classification (Trial of Org 10172) of NHOPI and Asians were compared with whites...
November 22, 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27721908/frailty-characteristics-in-chronic-hiv-patients-are-markers-of-white-matter-atrophy-independently-of-age-and-depressive-symptoms-a-pilot-study
#2
Kalpana J Kallianpur, Marissa Sakoda, Louie Mar A Gangcuangco, Lishomwa C Ndhlovu, Tracie Umaki, Dominic Chow, Suwarat Wongjittraporn, Cecilia M Shikuma
BACKGROUND: Chronic HIV disease is associated with neurocognitive impairment and age-related conditions such as frailty. OBJECTIVE: To determine whether regional brain volumetric changes correlate with frailty parameters in older (≥ 40 years) HIV+ patients on stable combination antiretroviral therapy. METHOD: Thirty-five HIV-infected participants in the Hawaii Aging with HIV Cohort - Cardiovascular Disease study underwent T1-weighted brain magnetic resonance imaging, frailty assessment and neuropsychological testing...
2016: Open Medicine Journal
https://www.readbyqxmd.com/read/27294768/cultural-dance-program-improves-hypertension-management-for-native-hawaiians-and-pacific-islanders-a-pilot-randomized-trial
#3
Joseph Keawe'aimoku Kaholokula, Mele Look, Tricia Mabellos, Guangxiang Zhang, Mapuana de Silva, Sheryl Yoshimura, Cappy Solatorio, Thomas Wills, Todd B Seto, Ka'imi A Sinclair
OBJECTIVE: Native Hawaiians and Pacific Islanders (NHPI) bear an unequal burden of hypertension and cardiovascular disease. Hula, the traditional dance of Hawaii, has shown to be a culturally meaningful form of moderate-vigorous physical activity for NHPI. A pilot study was done in Honolulu, Hawaii, to test a 12-week hula-based intervention, coupled with self-care education, on blood pressure management in NHPI with hypertension in 2013. METHOD: NHPI with a systolic blood pressure (SBP) ≥140 mmHg were randomized to the intervention (n = 27) or a wait-list control (n = 28)...
December 22, 2015: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/27097224/elevation-of-non-classical-cd14-lowcd16-monocytes-is-associated-with-increased-albuminuria-and-urine-tgf-%C3%AE-1-in-hiv-infected-individuals-on-stable-antiretroviral-therapy
#4
Brooks I Mitchell, Mary Margaret Byron, Roland C Ng, Dominic C Chow, Lishomwa C Ndhlovu, Cecilia M Shikuma
OBJECTIVE: High rates of albuminuria are observed among HIV-infected individuals on stable antiretroviral therapy (ART). Though pro-inflammatory and pro-fibrotic responses are described as components of albuminuria in the general population, it is unclear how these responses are associated to albuminuria in ART-treated chronic HIV. We investigated the relationship of monocyte subsets and urine inflammatory and fibrotic biomarkers to albuminuria in ART-treated HIV-infected participants...
2016: PloS One
https://www.readbyqxmd.com/read/26867220/non-classical-monocytes-and-monocyte-chemoattractant-protein-1-mcp-1-correlate-with-coronary-artery-calcium-progression-in-chronically-hiv-1-infected-adults-on-stable-antiretroviral-therapy
#5
Nath Zungsontiporn, Raquel R Tello, Guangxiang Zhang, Brooks I Mitchell, Matthew Budoff, Kalpana J Kallianpur, Beau K Nakamoto, Sheila M Keating, Philip J Norris, Lishomwa C Ndhlovu, Scott A Souza, Cecilia M Shikuma, Dominic C Chow
BACKGROUND: Persistent inflammation and immune activation has been hypothesized to contribute to increased prevalence of subclinical atherosclerosis and cardiovascular disease (CVD) risk in patients with chronic HIV infection. In this study, we examined the correlation of peripheral monocyte subsets and soluble biomarkers of inflammation to coronary artery calcium (CAC) progression, as measured by cardiac computed tomography scan. METHODS: We conducted a longitudinal analysis utilizing baseline data of 78 participants with HIV infection on stable antiretroviral therapy (ART) in the Hawaii Aging with HIV-Cardiovascular study who had available baseline monocyte subset analysis as well as CAC measurement at baseline and at 2-year follow up...
2016: PloS One
https://www.readbyqxmd.com/read/26777795/serum-amyloid-p-sap-is-associated-with-impaired-brachial-artery-flow-mediated-dilation-in-chronically-hiv-1-infected-adults-on-stable-antiretroviral-therapy
#6
Nath Zungsontiporn, Lishomwa C Ndhlovu, Brooks I Mitchell, James H Stein, Kalpana J Kallianpur, Beau Nakamoto, Sheila M Keating, Philip J Norris, Scott A Souza, Cecilia M Shikuma, Dominic C Chow
OBJECTIVE: This study aimed to evaluate the relationship between inflammatory biomarkers and endothelial dysfunction (ED), as measured by brachial artery flow-mediated dilation (FMD). METHODS: We conducted a cross-sectional analysis utilizing baseline data of 135 participants with HIV infection on stable antiretroviral therapy (ART) in the Hawaii Aging with HIV-Cardiovascular (HAHC-CVD) study who had available baseline inflammatory biomarkers and brachial artery FMD measurements...
November 2015: HIV Clinical Trials
https://www.readbyqxmd.com/read/26728928/the-associations-of-c-reactive-protein-with-serum-levels-of-polyunsaturated-fatty-acids-and-trans-fatty-acids-among-middle-aged-men-from-three-populations
#7
A El-Saed, K Masaki, T Okamura, R W Evans, Y Nakamura, B J Willcox, S Lee, H Maegawa, T B Seto, J Choo, A Fujiyoshi, K Miura, L H Kuller, H Ueshima, A Sekikawa
BACKGROUND: C-reactive protein (CRP) and many fatty acids (FAs) have been linked to cardiovascular disease. Associations of serum CRP with FAs in different populations have not been established. METHODS: Participants were 926 men aged 40-49 (2002-2006) from a population-based sample; 310 Whites from Pennsylvania, U.S., 313 Japanese from Shiga, Japan, and 303 Japanese Americans from Hawaii, U.S. Serum CRP (mg/L) was measured using immunosorbent assay while serum FAs (%) were measured using capillary-gas-liquid chromatography...
January 2016: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/26629706/environmental-predictors-of-us-county-mortality-patterns-on-a-national-basis
#8
Melissa P L Chan, Robert S Weinhold, Reuben Thomas, Julia M Gohlke, Christopher J Portier
A growing body of evidence has found that mortality rates are positively correlated with social inequalities, air pollution, elevated ambient temperature, availability of medical care and other factors. This study develops a model to predict the mortality rates for different diseases by county across the US. The model is applied to predict changes in mortality caused by changing environmental factors. A total of 3,110 counties in the US, excluding Alaska and Hawaii, were studied. A subset of 519 counties from the 3,110 counties was chosen by using systematic random sampling and these samples were used to validate the model...
2015: PloS One
https://www.readbyqxmd.com/read/26356593/serum-amyloid-p-sap-is-associated-with-impaired-brachial-artery-flow-mediated-dilation-in-chronically-hiv-1-infected-adults-on-stable-antiretroviral-therapy
#9
Nath Zungsontiporn, Lishomwa C Ndhlovu, Brooks I Mitchell, James H Stein, Kalpana J Kallianpur, Beau Nakamoto, Sheila M Keating, Philip J Norris, Scott A Souza, Cecilia M Shikuma, Dominic C Chow
OBJECTIVE: This study aimed to evaluate the relationship between inflammatory biomarkers and endothelial dysfunction (ED), as measured by brachial artery flow-mediated dilation (FMD). METHODS: We conducted a cross-sectional analysis utilizing baseline data of 135 participants with HIV infection on stable antiretroviral therapy (ART) in the Hawaii Aging with HIV-Cardiovascular (HAHC-CVD) study who had available baseline inflammatory biomarkers and brachial artery FMD measurements...
November 2015: HIV Clinical Trials
https://www.readbyqxmd.com/read/26218760/childhood-conscientiousness-and-leukocyte-telomere-length-40-years-later-in-adult-women-preliminary-findings-of-a-prospective-association
#10
Grant W Edmonds, Hélène C F Côté, Sarah E Hampson
Leukocyte telomere length (LTL) shortens with age, and is a prospective marker of mortality related to cardiovascular disease. Many health behaviors and social environmental factors have been found to be associated with LTL. Several of these are also associated with conscientiousness, a dispositional personality trait. Conscientiousness is a propensity to be planful, adhere to social norms, and inhibit pre-potent responses. Like LTL, conscientiousness is prospectively related to mortality, possibly through cumulative effects on health over the life course via multiple pathways...
2015: PloS One
https://www.readbyqxmd.com/read/26118142/stroke-disparities-disaggregating-native-hawaiians-from-other-pacific-islanders
#11
COMPARATIVE STUDY
Kazuma Nakagawa, Pippa R MacDonald, Susan M Asai
OBJECTIVES: To compare the clinical characteristics of Native Hawaiians (NH) and other Pacific Islanders (PI) who are hospitalized with ischemic stroke. DESIGN: Retrospective, cross-sectional analysis of medical records. SETTING: Tertiary, Primary Stroke Center in Honolulu, Hawaii. PATIENTS: Consecutive patients with race/ethnicity identified as NH or PI who were hospitalized for ischemic stroke between January 2006 and December 2012...
2015: Ethnicity & Disease
https://www.readbyqxmd.com/read/26038953/hiv-and-coronary-artery-calcium-score-comparison-of-the-hawaii-aging-with-hiv-cardiovascular-study-and-multi-ethnic-study-of-atherosclerosis-mesa-cohorts
#12
Dominic Chow, Rebekah Young, Nicole Valcour, Richard A Kronmal, Corey J Lum, Nisha I Parikh, Russell P Tracy, Matthew Budoff, Cecilia M Shikuma
OBJECTIVES: To determine the association of HIV, immunologic, and inflammatory factors on coronary artery calcium (CAC), a marker of subclinical atherosclerosis. METHODS: Cross-sectional study comparing baseline data of males from Hawaii Aging with HIV - Cardiovascular Study (HAHCS) with the Multi-Ethnic Study of Atherosclerosis (MESA) cohort. The cohorts were pooled to determine effects of HIV on CAC and explore immunologic and inflammatory factors that may explain development of CAC in HIV...
August 2015: HIV Clinical Trials
https://www.readbyqxmd.com/read/25739422/total-and-differential-white-blood-cell-counts-in-late-life-predict-8-year-incident-stroke-the-honolulu-heart-program
#13
Ji Young Huh, George Webster Ross, Randi Chen, Robert D Abbott, Christina Bell, Bradley Willcox, Lenore Launer, Helen Petrovitch, Brock Kaya, Kamal Masaki
OBJECTIVES: To study the association between total and differential white blood cell (WBC) count and incident stroke in an older Asian population. DESIGN: Prospective population-based study with 8 years of follow-up. SETTING: The Honolulu Heart Program, Oahu, Hawaii. PARTICIPANTS: Japanese-American men aged 71 to 93 who were free of stroke and had baseline WBC counts measured in 1991-93 (N=3,342). MEASUREMENTS: Participants were divided into quartiles of total and differential WBC count for analysis and were followed for incident stroke (thromboembolic and hemorrhagic (hemorrhagic)) for 8 years using data from a comprehensive hospital surveillance system...
March 2015: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/25733644/associations-of-key-diet-quality-indexes-with-mortality-in-the-multiethnic-cohort-the-dietary-patterns-methods-project
#14
MULTICENTER STUDY
Brook E Harmon, Carol J Boushey, Yurii B Shvetsov, Reynolette Ettienne, Jill Reedy, Lynne R Wilkens, Loic Le Marchand, Brian E Henderson, Laurence N Kolonel
BACKGROUND: Healthy dietary patterns have been linked positively with health and longevity. However, prospective studies in diverse populations in the United States addressing dietary patterns and mortality are limited. OBJECTIVE: We assessed the ability of the following 4 diet-quality indexes [the Healthy Eating Index-2010 (HEI-2010), the Alternative HEI-2010 (AHEI-2010), the alternate Mediterranean diet score (aMED), and the Dietary Approaches to Stop Hypertension (DASH)] to predict the reduction in risk of mortality from all causes, cardiovascular disease (CVD), and cancer...
March 2015: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/25535599/the-pili-ohana-project-a-community-academic-partnership-to-achieve-metabolic-health-equity-in-hawai-i
#15
Joseph Keawe'aimoku Kaholokula, Puni Kekauoha, Adrienne Dillard, Sheryl Yoshimura, Donna-Marie Palakiko, Claire Hughes, Claire Km Townsend
Native Hawaiians and Pacific Islanders (NHPI) have higher rates of excess body weight and related medical disorders, such as diabetes and cardiovascular disease, compared to other ethnic groups in Hawai'i. To address this metabolic health inequity, the Partnership for Improving Lifestyle Intervention (PILI) 'Ohana Project, a community-academic partnership, was formed over eight years ago and developed two community-placed health promotion programs: the PILI Lifestyle Program (PLP) to address overweight/obesity and the Partners in Care (PIC) to address diabetes self-care...
December 2014: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/25535597/kumu-hula-perspectives-on-health
#16
Mele A Look, Gregory G Maskarinec, Mapuana de Silva, Todd Seto, Marjorie L Mau, Joseph Keawe'aimoku Kaholokula
To prepare for research studies that would evaluate the impact of hula as part of a clinical intervention, including cardiovascular disease (CVD) prevention and management programs, kumu hula defined as "culturally recognized hula educators and experts," were interviewed. Investigators sought to elicit their views regarding hula's traditional and contemporary connections to health and well-being, assess the cultural appropriateness of such projects, and suggest ways to maintain hula's cultural integrity throughout clinical intervention programs...
December 2014: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/25514532/total-and-differential-white-blood-cell-counts-predict-eight-year-incident-coronary-heart-disease-in-elderly-japanese-american-men-the-honolulu-heart-program
#17
Shigehiko Karino, Bradley J Willcox, Kaon Fong, Serena Lo, Robert Abbott, Kamal H Masaki
BACKGROUND: Previous studies have reported an association between total and differential white blood cell (WBC) counts and incident coronary heart disease (CHD), but data from elderly populations are scarce. The purpose of this study was to examine the association between total and differential WBC counts and incident CHD in an elderly Japanese-American population. METHODS: Total and differential WBC counts were examined at a baseline examination from 1991 to 1993 in the Honolulu Heart Program...
February 2015: Atherosclerosis
https://www.readbyqxmd.com/read/25478304/tropic-lightning-myth-or-menace
#18
John McCarthy
Lightning is one of the leading causes of death related to environmental disaster. Of all lightning fatalities documented between 2006 and 2012, leisure activities contributed the largest proportion of deaths, with water-associated, sports, and camping being the most common. Despite the prevalence of these activities throughout the islands, Hawai'i has had zero documented lightning fatalities since weather data tracking was initiated in 1959. There is a common misconception that lightning does not strike the ground in Hawai'i...
November 2014: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/25205472/albuminuria-is-associated-with-elevated-acute-phase-reactants-and-proinflammatory-markers-in-hiv-infected-patients-receiving-suppressive-combination-antiretroviral-therapy
#19
Pichaya O-charoen, Lishomwa C Ndhlovu, Louie Mar A Gangcuangco, Sheila M Keating, Philip J Norris, Roland C K Ng, Brooks I Mitchell, Cecilia M Shikuma, Dominic C Chow
Albuminuria among HIV-infected individuals has been found to be associated with cardiovascular disease (CVD) and mortality. Inflammation has been associated with albuminuria. The pathophysiology of albuminuria in HIV-infected individuals is poorly understood. We investigated the association of albuminuria with inflammatory biomarkers among HIV-infected individuals on combination antiretroviral therapy (cART). This is a cross-sectional analysis of participants enrolled in the Hawaii Aging with HIV-Cardiovascular Cohort...
December 2014: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/24950146/fruit-and-vegetable-consumption-ethnicity-and-risk-of-fatal-ischemic-heart-disease
#20
S Sharma, S Vik, L N Kolonel
OBJECTIVE: Mortality rates from ischemic heart disease vary among ethnic groups. Dietary intake of fruits and vegetables has been associated with a lower risk of ischemic heart disease, but ethnic-specific data are limited. DESIGN: Prospective cohort study. SETTING: Hawaii and Los Angeles County, between 1993 and 1996. PARTICIPANTS: These analyses included 164,617 adults age 45 to 75, representing five ethnic groups who were enrolled in the Multiethnic Cohort Study...
2014: Journal of Nutrition, Health & Aging
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