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https://www.readbyqxmd.com/read/29684383/prognostic-role-of-haematological-indices-in-sudden-sensorineural-hearing-loss-review-and-meta-analysis
#1
REVIEW
Zaizai Cao, Ziyue Li, Haijie Xiang, Saiyu Huang, Jinjian Gao, Xiang Zhan, Xiuxiu Zhen, Bangliang Li, JianBin Wu, Bobei Chen
BACKGROUND: Complete blood count (CBC) is an important blood test in clinical practice, and it has been recently used to predict the prognosis of patients with sudden sensorineural hearing loss (SSNHL). Some haematological indices of the CBC test have been reported to be associated with the clinical outcome of SSNHL. However, the prognostic value of these haematological indices in SSNHL is currently under debate. Here, we performed a meta-analysis to investigate the association between haematological indices of the CBC test and clinical outcomes in patients with SSNHL...
April 20, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29684249/standard-head-down-tilt-versus-modified-without-head-down-tilt-postural-drainage-in-infants-and-young-children-with-cystic-fibrosis
#2
REVIEW
Diana A Freitas, Gabriela Ss Chaves, Thayla A Santino, Cibele Td Ribeiro, Fernando Al Dias, Ricardo O Guerra, Karla Mpp Mendonça
BACKGROUND: Postural drainage is used primarily in infants with cystic fibrosis from diagnosis up to the moment when they are mature enough to actively participate in self-administered treatments. However, there is a risk of gastroesophageal reflux associated with this technique.This is an update of a review published in 2015. OBJECTIVES: To compare the effects of standard postural drainage (15º to 45º head-down tilt) with modified postural drainage (15º to 30º head-up tilt) with regard to gastroesophageal reflux in infants and young children up to six years old with cystic fibrosis in terms of safety and efficacy...
March 9, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29684213/low-thyroid-function-is-not-associated-with-an-accelerated-deterioration-in-renal-function
#3
Christiaan L Meuwese, Merel van Diepen, Anne R Cappola, Mark J Sarnak, Michael G Shlipak, Douglas C Bauer, Linda P Fried, Massimo Iacoviello, Bert Vaes, Jean Degryse, Kay-Tee Khaw, Robert N Luben, Bjørn O Åsvold, Trine Bjøro, Lars J Vatten, Anton J M de Craen, Stella Trompet, Giorgio Iervasi, Sabrina Molinaro, Graziano Ceresini, Luigi Ferrucci, Robin P F Dullaart, Stephan J L Bakker, J Wouter Jukema, Patricia M Kearney, David J Stott, Robin P Peeters, Oscar H Franco, Henry Völzke, John P Walsh, Alexandra Bremner, José A Sgarbi, Rui M B Maciel, Misa Imaizumi, Waka Ohishi, Friedo W Dekker, Nicolas Rodondi, Jacobijn Gussekloo, Wendy P J den Elzen
Background: Chronic kidney disease (CKD) is frequently accompanied by thyroid hormone dysfunction. It is currently unclear whether these alterations are the cause or consequence of CKD. This study aimed at studying the effect of thyroid hormone alterations on renal function in cross-sectional and longitudinal analyses in individuals from all adult age groups. Methods: Individual participant data (IPD) from 16 independent cohorts having measured thyroid stimulating hormone, free thyroxine levels and creatinine levels were included...
April 18, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29684104/maternal-vitamin-d-supplementation-during-pregnancy
#4
Elizabeth M Curtis, Rebecca J Moon, Nicholas C Harvey, Cyrus Cooper
Introduction: Maternal vitamin D status in pregnancy has been linked to many health outcomes in mother and offspring. A wealth of observational studies have reported on both obstetric outcomes and complications, including pre-eclampsia, gestational diabetes, mode and timing of delivery. Many foetal and childhood outcomes are also linked to vitamin D status, including measures of foetal size, body composition and skeletal mineralization, in addition to later childhood outcomes, such as asthma...
April 19, 2018: British Medical Bulletin
https://www.readbyqxmd.com/read/29684028/does-chlorhexidine-reduce-bacteremia-following-tooth-extraction-a-systematic-review-and-meta-analysis
#5
Iciar Arteagoitia, Carlos Rodriguez Andrés, Eva Ramos
BACKGROUND AND AIMS: Scientific evidence is not clear regarding the use of antimicrobial mouth rinse before dental extraction to reduce bacteremia. We tested the null hypothesis that there would be no difference in the incidence of bacteremia following dental extractions in patients treated with or without chlorhexidine. MATERIAL AND METHODS: We conducted a meta-analysis following the recommendations proposed by PRISMA Preferred Reporting Items for Systematic Reviews and Meta-Analyses...
2018: PloS One
https://www.readbyqxmd.com/read/29684017/dissecting-the-null-model-for-biological-invasions-a-meta-analysis-of-the-propagule-pressure-effect
#6
Phillip Cassey, Steven Delean, Julie L Lockwood, Jason Sadowski, Tim M Blackburn
A consistent determinant of the establishment success of alien species appears to be the number of individuals that are introduced to found a population (propagule pressure), yet variation in the form of this relationship has been largely unexplored. Here, we present the first quantitative systematic review of this form, using Bayesian meta-analytical methods. The relationship between propagule pressure and establishment success has been evaluated for a broad range of taxa and life histories, including invertebrates, herbaceous plants and long-lived trees, and terrestrial and aquatic vertebrates...
April 23, 2018: PLoS Biology
https://www.readbyqxmd.com/read/29684016/correcting-for-batch-effects-in-case-control-microbiome-studies
#7
Sean M Gibbons, Claire Duvallet, Eric J Alm
High-throughput data generation platforms, like mass-spectrometry, microarrays, and second-generation sequencing are susceptible to batch effects due to run-to-run variation in reagents, equipment, protocols, or personnel. Currently, batch correction methods are not commonly applied to microbiome sequencing datasets. In this paper, we compare different batch-correction methods applied to microbiome case-control studies. We introduce a model-free normalization procedure where features (i.e. bacterial taxa) in case samples are converted to percentiles of the equivalent features in control samples within a study prior to pooling data across studies...
April 23, 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29683557/the-prevalence-of-gestational-diabetes-mellitus-in-mainland-china-a-systematic-review-and-meta-analysis
#8
Chenghan Gao, Xin Sun, Li Lu, Fangwei Liu, Jing Yuan
BACKGROUND: Pregnant women with gestational diabetes mellitus (GDM) are at a higher risk of adverse pregnancy outcomes.The aim of this study was to estimate the pooled prevalence of GDM in mainland China according to International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria. METHODS: We performed a systematic review by searching both English and Chinese literature databases. Random effects models were used to summarize the prevalence of GDM in mainland China...
April 23, 2018: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/29683475/pharmacological-interventions-for-the-prevention-of-insufficiency-fractures-and-avascular-necrosis-associated-with-pelvic-radiotherapy-in-adults
#9
REVIEW
Qurrat U van den Blink, Kate Garcez, Caroline C Henson, Susan E Davidson, Claire E Higham
BACKGROUND: Pelvic radiotherapy is a treatment delivered to an estimated 150,000 to 300,000 people annually across high-income countries. Fractures due to normal stresses on weakened bone due to radiotherapy are termed insufficiency fractures. Pelvic radiotherapy-related interruption of the blood supply to the hip is termed avascular necrosis and is another recognised complication. The reported incidences of insufficiency fractures are 2.7% to 89% and risk of developing avascular necrosis is 0...
April 23, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29683474/antidepressants-for-the-treatment-of-depression-in-people-with-cancer
#10
REVIEW
Giovanni Ostuzzi, Faith Matcham, Sarah Dauchy, Corrado Barbui, Matthew Hotopf
BACKGROUND: Major depression and other depressive conditions are common in people with cancer. These conditions are not easily detectable in clinical practice, due to the overlap between medical and psychiatric symptoms, as described by diagnostic manuals such as the Diagnostic and Statistical Manual of Mental Disorders (DSM) and International Classification of Diseases (ICD). Moreover, it is particularly challenging to distinguish between pathological and normal reactions to such a severe illness...
April 23, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29683066/identification-of-circulating-micrornas-as-diagnostic-biomarkers-for-ovarian-cancer-a-pooled-analysis-of-individual-studies
#11
Quan Zhou, Man-Zhen Zuo, Ze He, Hai-Rong Li, Wei Li
BACKGROUND: Circulating microRNAs (miRNAs) are proposed as promising non-invasive diagnostic biomarkers for many cancers. However, the diagnostic value of circulating miRNAs in ovarian cancer is inconsistent in different studies. Thus we performed this meta-analysis to systematically evaluate the diagnostic value of circulating miRNAs in ovarian cancer. METHODS: Eligible studies that were published prior to 30 June 2017 were searched from the PubMed, EMBASE, Cochrane Library, and Chinese National Knowledge Infrastructure...
April 1, 2018: International Journal of Biological Markers
https://www.readbyqxmd.com/read/29683035/is-peripherally-inserted-central-catheter-related-thrombosis-associated-with-abo-blood-group-a-case-control-pilot-study
#12
Raad A Haddad, Yanal Alnimer, Ahmed Abdalla, Carlos F Ríos-Bedoya, Ghassan Bachuwa
Peripherally inserted central catheter (PICC) use is associated with many complications including line-related thrombosis. Several studies and meta-analyses confirmed the increased risk to develop venous thromboembolism in non-O blood group individuals. Our pilot study aimed to examine whether PICC-related thrombosis is influenced by ABO blood group. We identified patients admitted to Hurley Medical Center between March 2012 and March 2016 who had PICC placed during their admission, had their ABO blood group identified in their medical record, and had upper extremity venous Doppler ultrasound performed on the same side of PICC...
January 1, 2018: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/29682972/parsing-and-quantification-of-raw-orbitrap-mass-spectrometer-data-using-rawquant
#13
Kevin A Kovalchik, Sophie Moggridge, David D Y Chen, Gregg B Morin, Christopher S Hughes
Effective analysis of protein samples by mass spectrometry (MS) requires careful selection and optimization of a range of experimental parameters. As the output from the primary detection device, the 'raw' MS data file can be used to gauge the success of a given sample analysis. However, the closed-source nature of the standard raw MS file can complicate effective parsing of the data contained within. To ease and increase the range of analyses possible, the RawQuant tool was developed to enable parsing of raw MS files derived from Thermo Orbitrap instruments to yield meta and scan data in an openly readable text format...
April 23, 2018: Journal of Proteome Research
https://www.readbyqxmd.com/read/29682912/diabetic-macular-oedema-under-represented-in-the-genetic-analysis-of-diabetic-retinopathy
#14
REVIEW
Suzanne Broadgate, Christine Kiire, Stephanie Halford, Victor Chong
Diabetic retinopathy, a complication of both type 1 and type 2 diabetes, is a complex disease and is one of the leading causes of blindness in adults worldwide. It can be divided into distinct subclasses, one of which is diabetic macular oedema. Diabetic macular oedema can occur at any time in diabetic retinopathy and is the most common cause of vision loss in patients with type 2 diabetes. The purpose of this review is to summarize the large number of genetic association studies that have been performed in cohorts of patients with type 2 diabetes and published in English-language journals up to February 2017...
April 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29682852/novel-in-silico-multivariate-mapping-of-intrinsic-and-anticorrelated-connectivity-to-neurocognitive-functional-maps-supports-the-maturational-hypothesis-of-adhd
#15
Nina de Lacy, Ian Kodish, Srinivas Rachakonda, Vince D Calhoun
From childhood to adolescence, strengthened coupling in frontal, striatal and parieto-temporal regions associated with cognitive control, and increased anticorrelation between task-positive and task-negative circuits, subserve the reshaping of behavior. ADHD is a common condition peaking in adolescence and regressing in adulthood, with a wide variety of cognitive control deficits. Alternate hypotheses of ADHD emphasize lagging circuitry refinement versus categorical differences in network function. However, quantifying the individual circuit contributions to behavioral findings, and relative roles of maturational versus categorical effects, is challenging in vivo or in meta-analyses using task-based paradigms within the same pipeline, given the multiplicity of neurobehavioral functions implicated...
April 22, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29682791/prevalence-of-refractive-errors-in-children-in-india-a-systematic-review
#16
REVIEW
Sethu Sheeladevi, Bharani Seelam, Phanindra B Nukella, Aditi Modi, Rahul Ali, Lisa Keay
Uncorrected refractive error is an avoidable cause of visual impairment which affects children in India. The objective of this review is to estimate the prevalence of refractive errors in children ≤ 15 years of age. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed in this review. A detailed literature search was performed to include all population and school-based studies published from India between January 1990 and January 2017, using the Cochrane Library, Medline and Embase...
April 22, 2018: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29682757/infrared-lasers-for-the-treatment-of-moderate-to-severe-periodontitis-an-american-academy-of-periodontology-best-evidence-review
#17
Leandro Chambrone, Umberto D Ramos, Mark A Reynolds
OBJECTIVE: This systematic review assesses the efficacy of infrared laser therapy used alone or as an adjunct to nonsurgical or surgical periodontal therapy, on clinical and patient-centered outcomes in patients with periodontitis. METHODS: Randomized clinical trials (RCTs) with a follow-up duration ≥ 3 months that evaluated root surface debridement (i.e., scaling and root debridement with or without surgical access) to laser therapy alone or laser therapy plus root surface debridement for the treatment of adult patients (≥18 years old) with moderate to severe aggressive or chronic periodontitis were considered eligible for inclusion...
April 22, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/29682699/effects-of-continuous-positive-airway-pressure-on-cardiovascular-biomarkers-in-patients-with-obstructive-sleep-apnea-a-meta-analysis-of-randomized-controlled-trials
#18
Yu Ning, Tian-Song Zhang, Wan-Wan Wen, Kun Li, Yun-Xiao Yang, Yan-Wen Qin, Hui-Na Zhang, Yun-Hui Du, Lin-Yi Li, Song Yang, Yun-Yun Yang, Miao-Miao Zhu, Xiao-Lu Jiao, Yan Zhang, Ming Zhang, Yong-Xiang Wei
PURPOSE: Obstructive sleep apnea (OSA) is associated with increased levels of systemic inflammatory markers, increased arterial stiffness, and endothelial dysfunction, which may lead to increased cardiovascular risk. We aimed to quantify the effects of continuous positive airway pressure (CPAP) on cardiovascular biomarkers and to establish predictors of response to CPAP. METHODS: We searched PubMed and the Cochrane Library from inception to May 31, 2017. Randomized controlled trials (RCTs) assessing the efficacy of CPAP on high-sensitivity C-reactive protein (hs-CRP), interleukin 6 (IL-6), tumor necrosis factor- alpha (TNF-α), augmentation index (AIx), pulse wave velocity (PWV), and flow-mediated dilatation (FMD) in patients with OSA were selected by consensus...
April 22, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29682310/rehabilitation-following-meniscal-repair-a-systematic-review
#19
Robert C Spang Iii, Michael C Nasr, Amin Mohamadi, Joseph P DeAngelis, Ara Nazarian, Arun J Ramappa
Objective: To review existing biomechanical and clinical evidence regarding postoperative weight-bearing and range of motion restrictions for patients following meniscal repair surgery. Methods and data sources: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline, we searched MEDLINE using following search strategy: (((("Weight-Bearing/physiology"[Mesh]) OR "Range of Motion, Articular"[Mesh]) OR "Rehabilitation"[Mesh])) AND ("Menisci, Tibial"[Mesh])...
2018: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29682210/age-at-menarche-and-risks-of-gestational-diabetes-mellitus-a-meta-analysis-of-prospective-studies
#20
Ya Xiao, Ruixue Chen, Minghao Chen, Anling Luo, Dayi Chen, Qiuer Liang, Yunfei Cai, Liguo Chen, Xiaoshan Zhao
Background: Accumulating evidence suggests that early menarche is associated with adult obesity, which in turn may increase the risk of insulin resistance and hyperglycemia. However, the relation of menarcheal age with gestational diabetes mellitus (GDM) remains inconsistent across studies. The objective of this meta-analysis was to evaluate the association between age at menarche and GDM risk. Materials and Methods: We searched Medline (PubMed), Embase, Web of Knowledge and the Cochrane library through the end of May 2017...
March 30, 2018: Oncotarget
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