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Medical complications in pregnancy

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https://www.readbyqxmd.com/read/29332178/association-of-autism-with-maternal-infections-perinatal-and-other-risk-factors-a-case-control-study
#1
Dikran Richard Guisso, Fadi S Saadeh, Dahlia Saab, Joud El Deek, Sarah Chamseddine, Hadi Abou El Hassan, Ghidaa Majari, Rose-Mary Boustany
This case-control study explores the association between pregnancy/birth complications and other factors with Autism Spectrum Disorder (ASD) in Lebanese subjects aged 2-18 years. Researchers interviewed 136 ASD cases from the American University of Beirut Medical Center Special Kids Clinic, and 178 controls selected by systematic digit dialing in the Greater-Beirut area. Male gender (Adjusted Odds Ratio [95% CI]: 3.9 [2.2-7.0]); postpartum feeding difficulties (2.5 [1.2-5.4]); maternal infections/complications during pregnancy (2...
January 13, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29324601/potentially-preventable-stillbirth-in-a-diverse-u-s-cohort
#2
Jessica M Page, Vanessa Thorsten, Uma M Reddy, Donald J Dudley, Carol J Rowland Hogue, George R Saade, Halit Pinar, Corette B Parker, Deborah Conway, Barbara J Stoll, Donald Coustan, Radek Bukowski, Michael W Varner, Robert L Goldenberg, Karen Gibbins, Robert M Silver
OBJECTIVE: To estimate the proportion of potentially preventable stillbirths in the United States. METHODS: We conducted a secondary analysis of 512 stillbirths with complete evaluation enrolled in the Stillbirth Collaborative Research Network from 2006 to 2008. The Stillbirth Collaborative Research Network was a multisite, geographically, racially, and ethnically diverse, population-based case-control study of stillbirth in the United States. Cases of stillbirth underwent standard evaluation that included maternal interview, medical record abstraction, biospecimen collection, postmortem examination, placental pathology, and clinically recommended evaluation...
January 9, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29323807/impact-of-obesity-on-cesarean-delivery-outcomes
#3
Andrew J Vegel, Dana M Benden, Andrew J Borgert, Kara J Kallies, Shanu N Kothari
BACKGROUND: The rate of cesarean delivery has increased over the last 2 decades. Obesity is a risk factor for complications during pregnancy and cesarean procedures. The objective of this study was to evaluate cesarean delivery outcomes in patients with vs without obesity, and determine the impact of obesity on complications. METHODS: The medical records of patients who underwent a cesarean delivery from 2010 to 2014 were reviewed. Patients were grouped by body mass index (BMI) into obese (≥30kg/m²) and non-obese (<30kg/m²) cohorts for comparison...
November 2017: WMJ: Official Publication of the State Medical Society of Wisconsin
https://www.readbyqxmd.com/read/29323064/vascular-endothelial-growth-factor-expression-in-placenta-of-hypertensive-disorder-in-pregnancy
#4
Abd Fuaat Azliana, Mohamad Razi Zainul-Rashid, Sabrina Florence Chandramaya, Wirda Indah Farouk, Alfian Nurwardah, Yin Ping Wong, Geok Chin Tan
INTRODUCTION: Hypertensive disorder in pregnancy (HDP) represents the most common medical complication in pregnancy. It is the leading cause of maternal and perinatal mortality and morbidity. Vascular endothelial growth factor (VEGF) stimulates vascular endothelial cell growth, survival, and proliferation, and they are known to be expressed in human placenta. The aim of this study was to determine the VEGF expression in the placenta of hypertensive and normotensive patients. MATERIALS AND METHODS: This is a retrospective, cross-sectional study from January 1, 2015 to December 31, 2015...
October 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29319359/secondary-and-tertiary-preventions-of-thyroid-disease
#5
Fereidoun Azizi, Ladan Mehran, Farhad Hosseinpanah, Hossein Delshad, Atieh Amouzegar
INTRODUCTION: Secondary and tertiary preventions are concerned with the recognition of the disease process in a very early stage and delay in progression to complete disease and minimization of complications and the impact of illness. METHODS: All articles related to secondary and tertiary prevention of thyroid diseases were reviewed. Using related key words, articles published between 2001 and 2015 were evaluated, categorized, and analyzed. RESULTS: In secondary prevention, congenital hypothyroidism and subclinical hypo and hyperthyroidism are equally important...
January 10, 2018: Endocrine Research
https://www.readbyqxmd.com/read/29318926/assessment-of-preeclampsia-risk-by-use-of-serum-ionized-magnesium-based-equation
#6
Chatchai Kreepala, Maethaphan Kitporntheranunt, Worrawat Sangwipasnapaporn, Warit Rungsrithananon, Krittanont Wattanavaekin
BACKGROUND: Preeclampsia is a common medical complication in pregnancy. It has been reported to be associated with decreased serum magnesium levels. However, there has not been evidence demonstrating utilization of change in magnesium for prediction of preeclampsia. The purpose of this study was to develop magnesium fraction-based equations which took other significant clinical risk factors into consideration for prediction of preeclampsia. METHODS: We collected serum total and ionized magnesium ionized magnesium levels from 84 pregnant women diagnosed with preeclampsia after week 20 of pregnancy...
November 2018: Renal Failure
https://www.readbyqxmd.com/read/29317608/epigenetics-and-cerebral-organoids-promising-directions-in-autism-spectrum-disorders
#7
REVIEW
Sheena Louise Forsberg, Mirolyuba Ilieva, Tanja Maria Michel
Autism spectrum disorders (ASD) affect 1 in 68 children in the US according to the Centers for Disease Control and Prevention (CDC). It is characterized by impairments in social interactions and communication, restrictive and repetitive patterns of behaviors, and interests. Owing to disease complexity, only a limited number of treatment options are available mainly for children that alleviate but do not cure the debilitating symptoms. Studies confirm a genetic link, but environmental factors, such as medications, toxins, and maternal infection during pregnancy, as well as birth complications also play a role...
January 10, 2018: Translational Psychiatry
https://www.readbyqxmd.com/read/29313912/complications-in-obstetric-anaesthesia
#8
REVIEW
L Maronge, D Bogod
'Obstetric anaesthesia is a litigious area of medical practice - patient expectations are high, and many of the interventions undertaken by anaesthetists are performed urgently or emergently, frequently out of hours. The complications that occur during obstetric practice are not unique to this area of anaesthesia, but some of the physiological and anatomical changes that take place during pregnancy can affect the frequency with which these happen. In this narrative review, we hope to cover a few of the more common complications in obstetric anaesthesia, as well as some of the more severe, yet less frequently occurring problems...
January 2018: Anaesthesia
https://www.readbyqxmd.com/read/29313509/patients-families-perceptions-of-lupus-in-sub-saharan-africa
#9
J Iba Ba, M Ouédraogo, Y S Oliveira, I Nseng Nseng, A Abo Ekomie, J B Boguikouma
Lupus is an autoimmune disease affecting the connective tissue. Its clinical and biological polymorphism is often misunderstood by patients and families and can lead to treatment interruption and a decision to turn to alternative medicine. We used a questionnaire to assess the degree of knowledge of this disease of family members living with lupus patients. Of the 56 lupus patients receiving regular follow-up at our hospital, 123 members of 30 of their families (53.5%) participated. Overall, among these families, 81...
November 1, 2017: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/29310986/multidisciplinary-obstetric-critical-care-delivery-the-concept-of-the-virtual-intensive-care-unit
#10
REVIEW
Michael P Leovic, Hailey N Robbins, Roman S Starikov, Michael R Foley
With an increasing prevalence of chronic medical conditions and the associated potential for decompensation to critical illness among modern day parturients, we present here the concept of the "virtual" intensive care unit. We challenge the traditional association of the word "unit" to extend beyond a fixed physical setting to portray an individualized, predetermined patient care team capable of managing these complex patients in a variety of settings. In this model, obstetric critical care is provided through a multidisciplinary patient care team, with emphasis on early identification of complicated pregnancies, detailed antepartum planning, anticipation of complications, and retrospective review of clinical outcomes aimed at continued quality improvement...
January 5, 2018: Seminars in Perinatology
https://www.readbyqxmd.com/read/29310480/can-sonographic-measurements-and-changes-in-cervical-length-during-pregnancy-predict-preterm-labour-in-an-asymptomatic-low-risk-population
#11
Omer Weitzner, Tal Biron-Shental, Yair Daykan, Osnat Ezra, Ofer Markovitch
OBJECTIVE: This study measured cervical length (CL) at 14-16 and 21-24 weeks of gestation and assessed whether the difference between measurements is predictive of preterm delivery (PTD). METHOD: This retrospective, cohort study included patients with two consecutive CL measured with transvaginal sonography at 14-16 weeks of gestation (CL1) and 21-24 weeks (CL2). Electronic medical records were reviewed for demographic, medical and obstetric history; complications during the current pregnancy and delivery data...
January 8, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29305253/chronic-hypertension-first-trimester-blood-pressure-control-and-likelihood-of-severe-hypertension-preeclampsia-and-small-for-gestational-age
#12
Diane Nzelu, Dan Dumitrascu-Biris, Kypros H Nicolaides, Nikos A Kametas
BACKGROUND: There is extensive evidence that pre-pregnancy chronic hypertension is associated with high risk of development of severe hypertension and preeclampsia and birth of small for gestational age neonates. However, previous studies have not reported whether anti-hypertensive use, blood pressure control or normalization of blood pressure during early pregnancy influence the rates of these pregnancy complications. OBJECTIVE: To stratify women with pre-pregnancy chronic hypertension according to the use of antihypertensive medications and level of blood pressure control at the first hospital visit during the first-trimester of pregnancy and examine the rates of severe hypertension, preeclampsia and birth of small for gestational age neonates according to such stratification...
January 2, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29304810/socioeconomic-status-can-affect-pregnancy-outcomes-and-complications-even-with-a-universal-healthcare-system
#13
Min Kyoung Kim, Seung Mi Lee, Sung-Hee Bae, Hyun Joo Kim, Nam Gu Lim, Seok-Jun Yoon, Jin Yong Lee, Min-Woo Jo
BACKGROUND: Low socioeconomic status can increase the risk of adverse pregnancy outcomes, but it remains unclear whether this negative association is attributed to inadequate prenatal care. Korea has been adopting a universal healthcare system. All Korean citizens must be enrolled National Health Insurance (NHI) or be recipient of Medical Aid (MA). In addition, Korean government launched a financial support system for antenatal care for all pregnant women in 2008. Therefore, in theory, there is no financial barrier to receive prenatal cares regardless of someone's social class...
January 5, 2018: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29304543/standardizing-second-trimester-medical-termination-effects-on-clinical-outcomes
#14
Michelle A Wyatt, Mary Catherine Tolcher
OBJECTIVE:  The objective of this study was to evaluate length of induction and postdelivery complications before and after implementation of a standardized approach to second-trimester medical termination of pregnancy. STUDY DESIGN:  This was a retrospective cohort study of all women undergoing medical termination of pregnancy between 130/7 and 266/7 weeks of gestation at a single, academic institution from July 1, 2012, through June 30, 2015. The primary outcome was the time from the start of induction of labor to delivery of the fetus...
January 5, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29304364/systematic-review-of-health-related-quality-of-life-and-patient-reported-outcome-measures-in-gestational-trophoblastic-disease-a-parallel-synthesis-approach
#15
REVIEW
Jane Ireson, Georgina Jones, Matthew C Winter, Stephen C Radley, Barry W Hancock, John A Tidy
Gestational trophoblastic disease is a rare complication of pregnancy that can develop into cancer. Medical outcomes of gestational trophoblastic disease are well researched, but the effect of the disease on health-related quality of life (HRQOL) requires attention if care is to be improved. This systematic review was designed to establish the effect of gestational trophoblastic disease and its treatment on HRQOL and to identify the appropriateness of HRQOL measures. Quantitative studies found HRQOL in long-term survivors of gestational trophoblastic disease to be at or above population norms...
January 2018: Lancet Oncology
https://www.readbyqxmd.com/read/29302809/preeclampsia-acts-differently-in-in-vitro-fertilization-versus-spontaneous-twins
#16
Rania Okby, Avi Harlev, Kira Nahum Sacks, Ruslan Sergienko, Eyal Sheiner
OBJECTIVE: To investigate risk factors and pregnancy outcome of spontaneous vs in-vitro fertilization (IVF) twins complicated with preeclampsia. STUDY DESIGN: A retrospective population-based cohort study comparing maternal and neonatal outcome in IVF vs spontaneously conceived twins was conducted. Deliveries occurred in a tertiary medical center between the years 1988 and 2010. Women who conceived after ovulation induction and those with chronic hypertension were excluded from the study...
January 4, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29302576/investigating-the-prevalence-of-preterm-birth-in-iranian-population-a-systematic-review-and-meta-analysis
#17
Nasibeh Sharifi, Somayyeh Khazaeian, Reza Pakzad, Azita Fathnezhad Kazemi, Hashemmieh Chehreh
Introduction: Despite medical advances, preterm delivery remains a global problem in developed and developing countries. The present study was aimed at conducting a systematic review and meta-analysis of studies on the prevalence of preterm delivery in Iran. Methods: This study was carried out on studies conducted in Iran by searching databases of SID, Magiran, Irandoc, MEDLIB, Iranmedex, PubMed, Web of science, Google Scholar and Scopus. The search was conducted using advanced search and keywords of preterm delivery and equivalents of it in Mesh and their Farsi's Synonymous in all articles from 2000-2016...
December 2017: Journal of Caring Sciences
https://www.readbyqxmd.com/read/29301729/preconception-care-in-diabetes-predisposing-factors-and-barriers
#18
Shaila Carrasco Falcón, Begoña Vega Guedes, Dácil Alvarado-Martel, Ana M Wägner
BACKGROUND AND OBJECTIVE: Preconception care has been shown to decrease the risk of pregnancy-related complications in women with diabetes, but many women do not plan their pregnancies. Our aim was to identify the associated factors and barriers related to involvement of these women in preconception care. MATERIAL AND METHODS: Fifty women with pregestational diabetes (28 with type 1 diabetes) and 50 non-diabetic pregnant women were consecutively enrolled at our hospital...
January 1, 2018: Endocrinología, Diabetes y Nutrición
https://www.readbyqxmd.com/read/29301466/immediate-perinatal-outcomes-of-postterm-deliveries
#19
Or Maoz, Tamar Wainstock, Eyal Sheiner, Asnat Walfisch
OBJECTIVE: To investigate whether postterm pregnancy (≥42 0/7 weeks' gestation) increases the risk for adverse perinatal outcome. STUDY DESIGN: In this population based cohort study, all singleton deliveries occurring between 1991 and 2014 in a tertiary medical center were included. Pregnancy and perinatal outcomes were compared between postterm and term deliveries (37 0/7 to 41 6/7 weeks' gestation). Preterm deliveries, unknown gestational age, congenital malformations, and multiple gestations, were excluded...
January 4, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29287946/what-we-do-and-do-not-know-about-women-and-kidney-diseases-questions-unanswered-and-answers-unquestioned-reflection-on-world-kidney-day-and-international-woman-s-day
#20
Giorgina B Piccoli, Mona Alrukhaimi, Zhi-Hong Liu, Elena Zakharova, Adeera Levin
Chronic kidney disease affects approximately 10% of the world's adult population: it is within the top 20 causes of death worldwide, and its impact on patients and their families can be devastating. World Kidney Day and International Women's Day in 2018 coincide, thus offering an opportunity to reflect on the importance of women's health and specifically their kidney health, on the community, and the next generations, as well as to strive to be more curious about the unique aspects of kidney disease in women so that we may apply those learnings more broadly...
December 26, 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
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