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https://www.readbyqxmd.com/read/29791616/short-and-long-latency-auditory-evoked-potentials-in-individuals-with-vestibular-dysfunction
#1
Valdete Alves Valentins Dos Santos Filha, Mirtes Bruckmann, Michele Vargas Garcia
Purpose Evaluate the auditory pathway at the brainstem and cortical levels in individuals with peripheral vestibular dysfunction. Methods The study sample was composed 19 individuals aged 20-80 years that presented exam results suggestive of Peripheral Vestibular Disorder (PVD) or Vestibular Dysfunction (VD). Participants underwent evaluation of the auditory pathway through Brainstem Auditory Evoked Potentials (BAEP) (short latency) and P1, N1, P2, N2, and P300 cortical potentials (long latency). Results Nine individuals presented diagnosis of VD and 10 participants were diagnosed with PVD...
2018: CoDAS
https://www.readbyqxmd.com/read/29790337/copper-i-usy-as-a-ligand-free-and-recyclable-catalyst-for-ullmann-type-o-n-s-and-c-arylation-reactions-scope-and-application-to-total-synthesis
#2
Tony Garnier, Mathieu Danel, Valentin Magne, Anthony Pujol, Valérie Beneteau, Patrick Pale, Stefan Chassaing
The copper(I)-doped zeolite CuI-USY proved to be a versatile, efficient, and recyclable catalyst for various Ullmann-type coupling reactions. Easy-to-prepare and cheap, this catalytic material enables the arylation and heteroarylation of diverse O-, N-, S- and C-nucleophiles under ligand-free conditions, while exhibiting large functional group compatibility. The facility of this catalyst to promote C-O bond formation was further demonstrated with the total synthesis of 3-methylobovatol, a naturally occurring diaryl ether of biological relevance...
May 23, 2018: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29790217/a-sonographic-classification-and-reporting-system-for-diagnosing-adenomyosis
#3
EDITORIAL
Thierry Van den Bosch, Annefleur M de Bruijn, Robert A de Leeuw, Margit Dueholm, Caterina Exacoustos, Lil Valentin, Tom Bourne, D Timmerman, Judith A F Huirne
OBJECTIVE: To develop a uniform classification and standardized reporting system of ultrasound findings of adenomyosis using the Morphological Uterus Sonographic Assessment (MUSA) criteria. METHOD: The opinion presented in this manuscript was built based on a thorough discussion among all authors, including a Delphi procedure. Selected images and videos of typical cases of the different morphological variations of adenomyosis were used in the debates. RESULTS: A classification and reporting system of different types of adenomyosis based on ultrasound was agreed upon including (1) identification of adenomyosis based on MUSA criteria, (2) disease location (anterior, posterior, left lateral, right lateral, fundal), (3) classification of the lesions as focal or diffuse, (4) presence or absence of intralesional cysts, (5) myometrial layer involvement (junctional zone, myometrium, serosal involvement), (6) disease extent (< 25%, 25-50%, > 50% of uterine volume affected by adenomyosis) and (7) lesion size...
May 22, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29788802/acute-effects-of-inhaled-menthol-on-the-rewarding-effects-of-intravenous-nicotine-in-smokers
#4
Gerald W Valentine, Elise E DeVito, Peter I Jatlow, Ralitza Gueorguieva, Mehmet Sofuoglu
OBJECTIVE: This double-blind, placebo controlled study examined whether menthol inhaled from an electronic cigarette (e-cigarette) would change subjective and withdrawal alleviating effects of intravenous nicotine in young adult smokers. METHODS: A total of 32 menthol-preferring smokers and 25 non-menthol-preferring smokers participated in the study that consisted of a random sequence of three different inhaled menthol conditions (0.0%, 0.5%, and 3.2%) across three test sessions (a single menthol condition per session)...
May 1, 2018: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/29788374/presence-of-hpv-apobec-related-minority-variants-in-hpv16-genomes-from-anal-and-cervical-samples-but-not-in-hpv52-and-hpv58
#5
Alice-Andrée Mariaggi, Hélène Péré, Marine Perrier, Benoit Visseaux, Gilles Collin, David Veyer, Quentin Le Hingrat, Valentine Marie Ferré, Véronique Joly, Anne Couvelard, Margot Bucau, Carine Davitian, Diane Descamps, Laurent Abramowitz, Charlotte Charpentier
Background: The aim of this study was to investigate the presence of minority variants (MV) in high-risk Human Papillomavirus types (hrHPV16, HPV52, HPV58) from cervical and anal smears. Methods: Whole HPV genome ultra-deep sequencing (UDS) was performed on cervical and anal smears collected during patients' follow-up. Bioinformatics analyses were performed using Bowtie2® (Geneious®). Results: We assessed 55 HPV16+, 20 HPV52+ and 17 HPV58+ samples, with significant differences in patient characteristics for the two anatomic sites...
May 17, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29787386/comparison-of-tracheal-intubation-conditions-in-operating-room-and-intensive-care-unit-a-prospective-observational-study
#6
Manuel Taboada, Patricia Doldan, Andrea Calvo, Xavier Almeida, Esteban Ferreiroa, Aurora Baluja, Agustin Cariñena, Paula Otero, Valentin Caruezo, Alberto Naveira, Pablo Otero, Julian Alvarez
BACKGROUND: Tracheal intubation is a common intervention in the operating room and in the intensive care unit. The authors hypothesized that tracheal intubation using direct laryngoscopy would be associated with worse intubation conditions and more complications in the intensive care unit compared with the operating room. METHODS: The authors prospectively evaluated during 33 months patients who were tracheally intubated with direct laryngoscopy in the operating room, and subsequently in the intensive care unit (within a 1-month time frame)...
May 22, 2018: Anesthesiology
https://www.readbyqxmd.com/read/29785383/valentine-s-day-misadventure-missing-vagina-for-urethra
#7
Ahmed Kamil, Claudiu Cozman, Asadullah Aslam, Nadeem Nusrat, Syed Jaffry
No abstract text is available yet for this article.
May 2018: Urology Case Reports
https://www.readbyqxmd.com/read/29785294/development-of-a-precision-multimodal-surgical-navigation-system-for-lung-robotic-segmentectomy
#8
Jean Marc Baste, Valentin Soldea, Samy Lachkar, Philippe Rinieri, Mathieu Sarsam, Benjamin Bottet, Christophe Peillon
Minimally invasive sublobar anatomical resection is becoming more and more popular to manage early lung lesions. Robotic-assisted thoracic surgery (RATS) is unique in comparison with other minimally invasive techniques. Indeed, RATS is able to better integrate multiple streams of information including advanced imaging techniques, in an immersive experience at the level of the robotic console. Our aim was to describe three-dimensional (3D) imaging throughout the surgical procedure from preoperative planning to intraoperative assistance and complementary investigations such as radial endobronchial ultrasound (R-EBUS) and virtual bronchoscopy for pleural dye marking...
April 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29784496/the-year-in-vascular-anesthesia-selected-highlights-from-2017
#9
Elizabeth A Valentine, Elizabeth Y Zhou, Emily K Gordon, E Andrew Ochroch
No abstract text is available yet for this article.
April 21, 2018: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29783835/dilational-visco-elasticity-of-proteins-solutions-in-dynamic-conditions
#10
Valentin B Fainerman, Volodymyr I Kovalchuk, Eugene V Aksenenko, Igor I Zinkovych, Alexander V Makievski, Mykola V Nikolenko, Reinhard Miller
Drop profile analysis tensiometry used in the oscillating drop mode provides the dilational visco-elasticity of adsorption layers at liquid interfaces. Applied during the progress of adsorption the dynamic surface rheology can be monitored. For β-casein solutions at the same surface pressure values, the dynamic dilational visco-elasticity is the larger, the longer the adsorption time is, i.e. the smaller the studied protein concentration is. For β-lactoglobulin and human serum albumin, the differences in the visco-elasticity values are less or not dependent on the adsorption time at identical surface pressures...
May 21, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29782864/are-dopamine-receptor-and-transporter-changes-in-rett-syndrome-reflected-in-mecp2-deficient-mice
#11
Dean F Wong, Mary E Blue, James R Brašić, Ayon Nandi, Heather Valentine, Kirstie H Stansfield, Olivier Rousset, Genila Bibat, Mary E Yablonski, Michael V Johnston, Albert Gjedde, SakkuBai Naidu
In the present study we tested the claim that the dopaminergic dysfunction of Rett Syndrome (RTT) also occurs in Mecp2-deficient mice that serve as a model of the syndrome. We used positron emission tomography (PET) to image dopamine D2 receptors (D2 R) and transporters (DAT) in women with RTT and in Mecp2-deficient mice, and D1 R and D2 R density was measured in postmortem human tissue by autoradiography. Results showed 1) significantly reduced D2 R density in the striatum of women with RTT compared to control subjects...
May 18, 2018: Experimental Neurology
https://www.readbyqxmd.com/read/29782823/changing-the-site-energy-of-per-614-in-the-peridinin-chlorophyll-a-protein-does-not-alter-its-capability-of-chlorophyll-triplet-quenching
#12
Alessandro Agostini, Jens Niklas, Tim Schulte, Marilena Di Valentin, Marco Bortolus, Eckhard Hofmann, Wolfgang Lubitz, Donatella Carbonera
The peridinin-chlorophyll-a protein (PCP) is a water-soluble light harvesting protein of the dinoflagellate Amphidinium carterae, employing peridinin (Per) as the main carotenoid to fulfil light harvesting and photo-protective functions. Per molecules bound to the protein experience specific molecular surroundings which lead to different electronic and spectral properties. In the refolded N89 L variant PCP (N89 L-RFPCP) a significant part of the intensity on the long wavelength side of the absorption spectrum is shifted to shorter wavelengths due to a significant change in the Per-614 site energy...
May 18, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29780368/-salmonella-enterica-prophage-sequence-profiles-reflect-genome-diversity-and-can-be-used-for-high-discrimination-subtyping
#13
Walid Mottawea, Marc-Olivier Duceppe, Andrée A Dupras, Valentine Usongo, Julie Jeukens, Luca Freschi, Jean-Guillaume Emond-Rheault, Jeremie Hamel, Irena Kukavica-Ibrulj, Brian Boyle, Alexander Gill, Elton Burnett, Eelco Franz, Gitanjali Arya, Joel T Weadge, Samantha Gruenheid, Martin Wiedmann, Hongsheng Huang, France Daigle, Sylvain Moineau, Sadjia Bekal, Roger C Levesque, Lawrence D Goodridge, Dele Ogunremi
Non-typhoidal Salmonella is a leading cause of foodborne illness worldwide. Prompt and accurate identification of the sources of Salmonella responsible for disease outbreaks is crucial to minimize infections and eliminate ongoing sources of contamination. Current subtyping tools including single nucleotide polymorphism (SNP) typing may be inadequate, in some instances, to provide the required discrimination among epidemiologically unrelated Salmonella strains. Prophage genes represent the majority of the accessory genes in bacteria genomes and have potential to be used as high discrimination markers in Salmonella ...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29779943/astroglial-cb-1-receptors-determine-synaptic-d-serine-availability-to-enable-recognition-memory
#14
Laurie M Robin, José F Oliveira da Cruz, Valentin C Langlais, Mario Martin-Fernandez, Mathilde Metna-Laurent, Arnau Busquets-Garcia, Luigi Bellocchio, Edgar Soria-Gomez, Thomas Papouin, Marjorie Varilh, Mark W Sherwood, Ilaria Belluomo, Georgina Balcells, Isabelle Matias, Barbara Bosier, Filippo Drago, Ann Van Eeckhaut, Ilse Smolders, Francois Georges, Alfonso Araque, Aude Panatier, Stéphane H R Oliet, Giovanni Marsicano
Bidirectional communication between neurons and astrocytes shapes synaptic plasticity and behavior. D-serine is a necessary co-agonist of synaptic N-methyl-D-aspartate receptors (NMDARs), but the physiological factors regulating its impact on memory processes are scantly known. We show that astroglial CB1 receptors are key determinants of object recognition memory by determining the availability of D-serine at hippocampal synapses. Mutant mice lacking CB1 receptors from astroglial cells (GFAP-CB1 -KO) displayed impaired object recognition memory and decreased in vivo and in vitro long-term potentiation (LTP) at CA3-CA1 hippocampal synapses...
May 15, 2018: Neuron
https://www.readbyqxmd.com/read/29779919/radiation-dose-constraints-for-organs-at-risk-in-neuro-oncology-the-european-particle-therapy-network-consensus
#15
REVIEW
Maarten Lambrecht, Daniëlle B P Eekers, Claire Alapetite, Neil G Burnet, Valentin Calugaru, Ida E M Coremans, Piero Fossati, Morten Høyer, Johannes A Langendijk, Alejandra Méndez Romero, Frank Paulsen, Ana Perpar, Laurette Renard, Dirk de Ruysscher, Beate Timmermann, Pavel Vitek, Damien C Weber, Hiske L van der Weide, Gillian A Whitfield, Ruud Wiggenraad, Erik Roelofs, Petra Witt Nyström, Esther G C Troost
PURPOSE: For unbiased comparison of different radiation modalities and techniques, consensus on delineation of radiation sensitive organs at risk (OARs) and on their dose constraints is warranted. Following the publication of a digital, online atlas for OAR delineation in neuro-oncology by the same group, we assessed the brain OAR-dose constraints in a follow-up study. METHODS: We performed a comprehensive search to identify the current papers on OAR dose constraints for normofractionated photon and particle therapy in PubMed, Ovid Medline, Cochrane Library, Embase and Web of Science...
May 17, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29779798/identification-of-factors-predictive-of-postoperative-morbidity-and-short-term-mortality-in-older-patients-after-colorectal-carcinoma-resection-a-single-center-retrospective-study
#16
Teresa Schreckenbach, Matthias Valentin Zeller, Hanan El Youzouri, Wolf Otto Bechstein, Guido Woeste
OBJECTIVES: The aim of this study is to investigate the effect of age on patient outcome after colorectal carcinoma (CRC) resection in patients over 65 years of age. METHODS: This study included patients aged 65 years and older who underwent CRC resection between 2003 and 2013 at a single-center institution. Patients were divided into two groups: Group A (65-74 years old) and Group B (≥75 years old). RESULTS: Multivariable logistic analysis of 415 patients revealed serum albumin levels on the third postoperative day (POD) (Odds Ratio (OR), 0...
May 17, 2018: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/29779686/a-2ma-old-baboon-like-monkey-from-northern-greece-and-new-evidence-to-support-the-paradolichopithecus-procynocephalus-synonymy-primates-cercopithecidae
#17
Dimitris S Kostopoulos, Franck Guy, Zoi Kynigopoulou, George D Koufos, Xavier Valentin, Gildas Merceron
A new fossil cranium of a large papionin monkey from the Lower Pleistocene site of Dafnero-3 in Western Macedonia, Greece, is described by means of outer and inner morphological and metric traits using high-resolution micro-computed tomography. Comparisons with modern cercopithecids and contemporaneous Eurasian fossil taxa suggest that the new cranium could equally be ascribed to either the Eurasian Paradolichopithecus or to the East Asian Procynocephalus. The combination of the available direct and indirect fossil evidence, including the new cranium from Dafnero, revives an earlier hypothesis that considers these two sparsely documented genera as synonyms...
May 17, 2018: Journal of Human Evolution
https://www.readbyqxmd.com/read/29779387/-assessment-of-health-related-quality-of-life-in-psoriasis-patients-in-hungary
#18
Adrienn Katalin Poór, Miklós Sárdy, Tamás Cserni, Valentin Brodszky, Péter Holló, László Gulácsi, Éva Remenyik, Andrea Szegedi, Fanni Rencz, Márta Péntek
INTRODUCTION: The health status and health-related quality of life (HRQoL) of patients with psoriasis in Hungary are understudied. AIM: To assess HRQoL in psoriasis patients, to compare HRQoL of psoriasis patients to that of the general public in Hungary and to identify predictors of HRQoL. METHOD: Between 2012 and 2016, two cross-sectional surveys were carried out among psoriasis patients at two academic dermatology departments. HRQoL was assessed by EQ-5D-3L, EQ Visual Analogue Scale (EQ VAS) and Dermatology Life Quality Index (DLQI)...
May 2018: Orvosi Hetilap
https://www.readbyqxmd.com/read/29777691/improving-electrical-properties-of-ipsc-cardiomyocytes-by-enhancing-cx43-expression
#19
Valentin Sottas, Carl-Mattheis Wahl, Mihnea C Trache, Michael Bartolf-Kopp, Sidney Cambridge, Markus Hecker, Nina D Ullrich
The therapeutic potential of induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) is limited by immature functional features including low impulse propagation and reduced cell excitability. Key players regulating electrical activity are voltage-gated Na+ channels (Nav 1.5) and gap junctions built from connexin-43 (Cx43). Here we tested the hypothesis that enhanced Cx43 expression increases intercellular coupling and influences excitability by modulating Nav 1.5. Using transgenic approaches, Cx43 and Nav 1...
May 16, 2018: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/29776444/mediastinal-staging-of-non-small-cell-lung-cancer-by-endobronchial-and-endoscopic-ultrasonography-with-or-without-additional-surgical-mediastinoscopy-mediastrial-study-protocol-of-a-multicenter-randomised-controlled-trial
#20
Jelle E Bousema, Marcel G W Dijkgraaf, Nicole E Papen-Botterhuis, Hermien W Schreurs, Jos G Maessen, Erik H van der Heijden, Willem H Steup, Jerry Braun, Valentin J J M Noyez, Fieke Hoeijmakers, Naomi Beck, Martijn van Dorp, Niels J M Claessens, Birgitta I Hiddinga, Johannes M A Daniels, David J Heineman, Harmen R Zandbergen, Ad F T M Verhagen, Paul E van Schil, Jouke T Annema, Frank J C van den Broek
BACKGROUND: In case of suspicious lymph nodes on computed tomography (CT) or fluorodeoxyglucose positron emission tomography (FDG-PET), advanced tumour size or central tumour location in patients with suspected non-small cell lung cancer (NSCLC), Dutch and European guidelines recommend mediastinal staging by endosonography (endobronchial ultrasound (EBUS) and endoscopic ultrasound (EUS)) with sampling of mediastinal lymph nodes. If biopsy results from endosonography turn out negative, additional surgical staging of the mediastinum by mediastinoscopy is advised to prevent unnecessary lung resection due to false negative endosonography findings...
May 18, 2018: BMC Surgery
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