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https://www.readbyqxmd.com/read/29909229/functional-evaluation-of-bilateral-subtalar-arthroereisis-for-the-correction-of-flexible-flatfoot-in-children-1-year-follow-up
#1
Paolo Caravaggi, Giada Lullini, Lisa Berti, Sandro Giannini, Alberto Leardini
BACKGROUND: Flexible flatfoot (FFF) is a common alteration of the foot diagnosed in the pediatric population causing pain and decreased quality of life. Surgical treatment via arthroereisis of the subtalar joint can be recommended when non-invasive options do not result in sufficient pain relief. While clinical outcome of subtalar joint arthroereisis is generally positive, no functional evaluation has thus far been reported following surgery. RESEARCH QUESTION: The aim of this study was to assess the effects of two arthroereisis implants for the correction of bilateral FFF on foot and lower limb biomechanics during gait...
June 11, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29908796/mortality-and-implant-survival-with-simultaneous-and-staged-bilateral-total-knee-arthroplasty-experience-from-the-australian-orthopaedic-association-national-joint-replacement-registry
#2
Hwa Sen Chua, Sarah L Whitehouse, Michelle Lorimer, Richard De Steiger, Linda Guo, Ross W Crawford
BACKGROUND: Total knee arthroplasty (TKA) is an effective procedure for relieving pain and restoring function in osteoarthritis, with a significant proportion of patients having severe disease bilaterally. However, although there are differences in patient selection criteria for bilateral procedures, there is no consensus regarding the optimal timing for bilateral TKA. The aim of this study was to compare rates and causes of revision and 30-day mortality between simultaneous and staged bilateral TKA using data from the Australian Orthopaedic Association National Joint Replacement Registry...
May 17, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29908488/effect-of-dissolution-of-magnesium-alloy-az31-on-the-rheological-properties-of-phosphate-buffer-saline
#3
Usman Riaz, Leela Rakesh, Ishraq Shabib, Waseem Haider
The issue of long-term incompatible interactions associated with the permanent implants can be eliminated by using various biodegradable metal implants. The recent research is focusing on the use of degradable stents to restore most of the hindrances of capillaries, and coronary arteries by supplying instant blood flow with constant mechanical and structural support. However, internal endothelialization and infection due to the corrosion of implanted stents are not easy to diagnose in the long run. In the recent past, magnesium (Mg) has been widely investigated for the cardiovascular stent applications...
June 5, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29905641/surgical-treatment-of-diplopia-in-graves-orbitopathy-patients
#4
Anja Eckstein, Joachim Esser, Michael Oeverhaus, Peerooz Saeed, Hinke Marijke Jellema
PURPOSE: To review the authors' current understanding of motility dysfunction in patients with thyroid eye disease and to summarize appropriate evaluation and available management options. METHODS: Data were retrieved from a systematic search of the literature. RESULTS: Diplopia is one of the most disabling symptoms for Graves orbitopathy patients. It occurs in moderate-to-severe Graves orbitopathy stages and does not respond well to available anti-inflammatory treatment...
June 13, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29898490/-temporary-pacemakers-step-by-step
#5
Matthias Graf, Patrick Stiller, Martin Karch
Symptomatic bradycardia is usually caused by abnormalities of atrioventricular conduction or sinus node dysfunction. Reversible and irreversible causes must be considered.Temporary pacemakers are used in the emergency treatment in case of severe bradyarrhythmia.They help to bridge the acute phase until spontaneous restoration of atrioventricular or sinus node function or -if spontaneous restoration fails- until a permanent pacemaker system was implanted.In the following article we discuss the commonly used temporary pacemaker systems...
June 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29897818/androgens-induce-growth-of-the-limb-skeletal-muscles-in-a-rapamycin-insensitive-manner
#6
Michael L Rossetti, David H Fukuda, Bradley S Gordon
Signaling through the mechanistic target of rapamycin complex 1 (mTORC1) has been well-defined as an androgen-sensitive transducer mediating skeletal muscle growth in vitro, however, this has yet to be tested in vivo. As such, male mice were subjected to either sham or castration surgery and allowed to recover for 7 weeks to induce atrophy of skeletal muscle. Then, castrated mice were implanted with either a control pellet or pellet that administered rapamycin (~2.5 mg/kg/day). Seven days post implant, a subset of castrated mice with control pellets and all castrated mice with rapamycin pellets were given once weekly injections of nandrolone decanoate (ND) to induce muscle growth over a 6-week period...
June 13, 2018: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/29897351/midfacial-tissue-assessment-of-the-effect-of-amount-of-keratinized-mucosa-on-immediate-temporarization-of-fresh-socket-implants-8-year-follow-up
#7
Roberto Crespi, Paolo Capparé, Giovanni Crespi, Giorgio Gastaldi, Georgios E Romanos, Enrico Gherlone
The aim of the present study was to consider the long-term midfacial mucosal outcome around final prosthetic restorations on dental implants placed and loaded immediately after tooth extractions. A total of 42 patients requiring tooth extractions were recruited, and 142 teeth were extracted. Based on the amount of keratinized mucosa (KM), implants were categorized into group A (KM ≥ 2 mm; n = 61) or group B (KM < 2 mm; n = 62). In both groups, all patients received temporary prosthetic restorations immediately after the surgical procedure...
June 12, 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29896546/abundant-heterotopic-bone-formation-following-use-of-rhbmp-2-in-the-treatment-of-acetabular-bone-defects-during-revision-hip-arthroplasty
#8
Alexander Arzeno, Tim Wang, James I Huddleston
Revision hip arthroplasty in the setting of periacetabular bone loss presents a significant challenge, as options for restoring bone loss are limited. Recombinant human bone morphogenetic protein-2 may offer a solution by promoting bone growth to restore bone stock before implant reimplantation. Here we present a case of a patient with a periprosthetic acetabulum fracture, resulting in pelvic discontinuity as the result of significant periacetabular bone loss. Using a staged approach, periacetabular bone stock was nearly entirely reconstituted using recombinant BMPs and allograft, which resulted in stable fixation, but with abundant heterotopic bone formation...
June 2018: Arthroplasty Today
https://www.readbyqxmd.com/read/29896455/acetabular-cup-revision-arthroplasty-using-morselized-impaction-allograft
#9
REVIEW
Joong-Myung Lee, Tae-Ho Kim
The rate of acetabular cup revision arthroplasty is gradually rising along with an increased risk of osteolysis and prosthesis loosening over time and an increase in life expectancy. The goals of revision total hip arthroplasty are: i) implant stability through reconstruction of large bone defects, ii) restoration of range of motion and biomechanics of the hip joint, and iii) normalization of uneven limb lengths. In acetabular cup revision arthroplasty, stable fixation of acetabular components is difficult in the presence of severe bone loss (e...
June 2018: Hip & Pelvis
https://www.readbyqxmd.com/read/29894550/stability-of-implant-abutment-connection-after-using-the-rescue-kit-an-in-vitro-study
#10
Achim Sprenger, Kristupas Gutauskas, Andreas Filippi, Martin Rosentritt, Sebastian Kühl
PURPOSE: To evaluate whether removing a fractured abutment screw with a specific rescue device negatively affects the success of a new restoration in terms of early abutment loosening. MATERIALS AND METHODS: Implants (n = 10) with a regular platform of 4.1 mm (tissue level [TL]) and implants (n = 10) with a reduced diameter of 3.3 mm (bone level [BL]) were used. The screws of eight respective abutments for both implant types were artificially weakened in order to fracture during torque application for abutment insertion...
June 12, 2018: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29893541/hierarchical-self-healing-and-superhydrophobic-zirconium-phosphate-hybrid-membrane-based-on-the-interfacial-crystal-growth-of-lyotropic-2d-nanoplatelets
#11
Minxiang Zeng, Pingmei Wang, Jianhui Luo, Baoliang Peng, Bin Ding, Lecheng Zhang, Ling Wang, Dali Huang, Ian Echols, Ehab Abo Deeb, Eric Bordovsky, Chang-Hyun Choi, Carlos Ybanez, Patricia Meras, Evan Situ, M Sam Mannan, Zhengdong Cheng
We demonstrate a facile route to in situ growth of lyotropic zirconium phosphate (ZrP) nanoplates on textiles via an interfacial crystal growing process. The as-prepared hybrid membrane shows a hierarchical architecture of textile fibers (porous platform for fluid transport), ZrP nanoplatelets (layered scaffolds for chemical barriers), and octadecylamine (organic species for superhydrophobic functionalization). Interestingly, such hybrid membrane is able to separate the oily wastewater with high separation efficiency of 99...
June 12, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29891731/local-bdnf-delivery-to-the-injured-cervical-spinal-cord-using-an-engineered-hydrogel-enhances-diaphragmatic-respiratory-function
#12
Biswarup Ghosh, Zhicheng Wang, Jia Nong, Mark W Urban, Zhiling Zhang, Victoria A Trovillion, Megan C Wright, Yinghui Zhong, Angelo C Lepore
We developed an innovative biomaterial-based approach to repair the critical neural circuitry that controls diaphragm activation by locally delivering brain-derived neurotrophic factor (BDNF) to injured cervical spinal cord. BDNF can be used to restore respiratory function via a number of potential repair mechanisms; however, widespread BDNF biodistribution resulting from delivery methods such as systemic injection or lumbar puncture can lead to inefficient drug delivery and adverse side effects. As a viable alternative, we developed a novel hydrogel-based system loaded with polysaccharide-BDNF particles self-assembled by electrostatic interactions that can be safely implanted in the intrathecal space for achieving local BDNF delivery with controlled dosing and duration...
June 11, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29889914/flapless-postextraction-socket-implant-placement-part-3-the-effects-of-bone-grafting-and-provisional-restoration-on-soft-tissue-color-change-a-retrospective-pilot-study
#13
Stephen J Chu, Hanae Saito, Maurice A Salama, David A Garber, Henry Salama, Guido O Sarnachiaro, Mark A Reynolds, Dennis P Tarnow
This article presents the results of a soft tissue color study on flapless immediate implant therapy from a sample of 23 patients who received either a provisional restoration alone or with bone grafting. The gingival color in clinical photographs was measured for the implant and for the contralateral tooth site at 2.0 and 5.0 mm below the free gingival margin using Photoshop software (Lightroom CC, Adobe). The average color difference (ΔE) values for the two groups were 2.6 and 2.4 at 2.0 mm and 1.9 and 2...
July 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29889780/the-sound-of-a-cochlear-implant-investigated-in-patients-with-single-sided-deafness-and-a-cochlear-implant
#14
Jeroen P M Peters, Anne W Wendrich, Ruben H M van Eijl, Koenraad S Rhebergen, Huib Versnel, Wilko Grolman
HYPOTHESIS: A cochlear implant (CI) restores hearing in patients with profound sensorineural hearing loss by electrical stimulation of the auditory nerve. It is unknown how this electrical stimulation sounds. BACKGROUND: Patients with single-sided deafness (SSD) and a CI form a unique population, since they can compare the sound of their CI with simulations of the CI sound played to their nonimplanted ear. METHODS: We tested six stimuli (speech and music) in 10 SSD patients implanted with a CI (Cochlear Ltd)...
July 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29888347/the-challenge-of-managing-patients-with-generalized-short-root-anomaly-a-case-report
#15
Dimitrios Michelogiannakis, Heleni Vastardis, Ioannis Melakopoulos, Chrysanthy Papathanasopoulou, Konstantinos I Tosios
The case of an 18-year-old woman with generalized short root anomaly (SRA) is presented, and the clinical management and challenges associated with this rare condition are discussed. The patient was referred for restoration of the edentulous maxillary left anterior region. Due to the SRA, the patient had previously received limited orthodontic treatment for the ectopic maxillary canines. The maxillary left canine failed during orthodontic traction, the left lateral incisor migrated in its region and had poor prognosis due to severe mobility...
June 8, 2018: Quintessence International
https://www.readbyqxmd.com/read/29886385/transcutaneously-refillable-3d-printed-biopolymeric-encapsulation-system-for-the-transplantation-of-endocrine-cells
#16
Marco Farina, Corrine Ying Xuan Chua, Andrea Ballerini, Usha Thekkedath, Jenolyn F Alexander, Jessica R Rhudy, Gianluca Torchio, Daniel Fraga, Ravi R Pathak, Mariana Villanueva, Crystal S Shin, Jean A Niles, Raffaella Sesana, Danilo Demarchi, Andrew G Sikora, Ghanashyam S Acharya, A Osama Gaber, Joan E Nichols, Alessandro Grattoni
Autologous cell transplantation holds enormous promise to restore organ and tissue functions in the treatment of various pathologies including endocrine, cardiovascular, and neurological diseases among others. Even though immune rejection is circumvented with autologous transplantation, clinical adoption remains limited due to poor cell retention and survival. Cell transplant success requires homing to vascularized environment, cell engraftment and importantly, maintenance of inherent cell function. To address this need, we developed a three dimensional (3D) printed cell encapsulation device created with polylactic acid (PLA), termed neovascularized implantable cell homing and encapsulation (NICHE)...
May 30, 2018: Biomaterials
https://www.readbyqxmd.com/read/29885962/does-a-fixed-offset-hemiarthroplasty-implant-have-any-effect-on-pain-and-function-in-patients-with-a-femoral-neck-fracture
#17
Bola Akinola, Ruaraidh Collins, Francis C J Sim, Martyn J Parker
INTRODUCTION: Hip hemiarthroplasty is the commonest operation performed for a displaced intracapsular hip fracture in the UK. A variety of implants including fixed offset prostheses are utilised. There has been no study investigating the relationship between restoration of femoral offset and long term pain and function. This study aims to evaluate long-term pain and functional outcomes of a fixed offset hemiarthroplasty implant (the Exeter trauma system). PATIENTS AND METHODS: All patients were retrospectively reviewed from a prospectively collected database...
May 26, 2018: Injury
https://www.readbyqxmd.com/read/29884312/survival-of-dental-implants-placed-in-vascularised-fibula-free-flaps-after-jaw-reconstruction
#18
Sameh Attia, Joerg Wiltfang, Jörn Pons-Kühnemann, Jan-Falco Wilbrand, Philipp Streckbein, Christopher Kähling, Hans-Peter Howaldt, Heidrun Schaaf
PURPOSE: Ablative oncological surgery to treat head-and-neck cancer often triggers a requirement for jaw reconstruction. Modern surgical procedures using free microvascular flaps afford acceptable outcomes in terms of restoration of bony and soft tissue defects. A fibula free flap is often the preferred flap, as the bone length is considerable and a two-surgeon approach is possible. Dental implants play important roles in functional rehabilitation. Our aim was to evaluate the survival of dental implants placed in reconstructed areas after transfer of fibula tissue to the jaw...
June 5, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29883813/comparative-analysis-of-two-porcine-kidney-decellularization-methods-for-maintenance-of-functional-vascular-architectures
#19
Joao Paulo Zambon, In Kap Ko, Mehran Abolbashari, Jennifer Huling, Cara Clouse, Tae Hyoung Kim, Charesa Smith, Anthony Atala, James J Yoo
Kidney transplantation is currently the only definitive solution for the treatment of end-stage renal disease (ESRD), however transplantation is severely limited by the shortage of available donor kidneys. Recent progress in whole organ engineering based on decellularization/recellularization techniques has enabled pre-clinical in vivo studies using small animal models; however, these in vivo studies have been limited to short-term assessments. We previously developed a decellularization system that effectively removes cellular components from porcine kidneys...
June 5, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29882338/minimally-invasive-treatment-of-an-adult-with-severe-pseudo-class-iii-malocclusion
#20
Farhad Vahidi
Pseudo class III malocclusion is reverse anterior occlusion or anterior cross-bite with first molars and canines in a class I relationship. It is very important to diagnose the pseudo class III from true skeletal class III. The combination of anterior displacement of the mandible, tooth wear, and loss of occlusal vertical dimension (OVD) in adults may result anterior cross-bite. The key factor in diagnosis of this malocclusion is an interdisciplinary approach with an orthodontist. Cephalometric images are essential for diagnosis of pseudo class III mal-occlusion...
June 7, 2018: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
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