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https://www.readbyqxmd.com/read/29158173/standardized-and-simplified-retroperitoneal-lymph-node-dissection-during-retroperitoneal-laparoscopic-radical-nephroureterectomy-for-urothelial-carcinoma-of-the-upper-ureter-or-renal-pelvis-en-bloc-resection-technique
#1
Toru Kanno, Go Kobori, Masashi Kubota, Satoshi Funada, Takao Haitani, Takashi Okada, Yoshihito Higashi, Seiji Moroi, Hitoshi Yamada
OBJECTIVE To describe our en-bloc technique of retroperitoneal lymph node dissection (RPLND) during retroperitoneal laparoscopic radical nephroureterectomy (RNU) for upper urinary tract urothelial carcinoma (UTUC) and evaluate perioperative outcomes. METHODS From 2002 to 2015, 114 patients with UTUC located at the pelvis and/or upper or middle ureter underwent retroperitoneal laparoscopic RNU at two institutions. Performance of RPLND began in February 2009. The template of RPLND included the renal hilar and para-aortic lymph nodes (left side) and the renal hilar, paracaval, retrocaval, and intra-aortocaval lymph nodes (right side)...
November 17, 2017: Urology
https://www.readbyqxmd.com/read/29135122/the-role-of-the-multidisciplinary-team-in-the-decision-making-process-in-stage-one-testicular-cancer-retrospective-cohort-analysis
#2
Tomislav Omrcen, Andrija Katic, Eduard Vrdoljak
PURPOSE: To analyze the role of a multidisciplinary team (MDT) in the decision-making process in clinical stage one (CS I) testicular cancer (TC). METHODS: We retrospectively evaluated data on 115 consecutive patients with CS I TC (excluding stage IS) who were referred to the Department of Oncology, University Hospital of Split, Croatia, from 2003 to 2012. Fifty-six patients (48.7%) were referred between 2003 and 2007, before the introduction of the MDT and 59 patients (51...
September 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/29129354/surgical-management-and-outcomes-of-patients-with-bone-metastases-in-germ-cell-tumors-a-case-series
#3
Alessandro Nini, Marcus Konieczny, Christian Winter, Achim Lusch, Rüdiger Krauspe, Peter Albers
OBJECTIVE: To report perioperative and oncological outcomes of patients with nodal and bone involvement treated with postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) and simultaneous bone resection (BR). PATIENTS AND METHODS: Between 2008 and 2016, 14 consecutive unselected TC patients with nodal and bone involvement underwent PC-RPLND and BR. Surgery was performed together with orthopedic surgeons. Standard PC-RPLNDs were performed in 4 patients...
November 9, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/29104087/long-term-survival-of-good-risk-germ-cell-tumor-patients-after-postchemotherapy-retroperitoneal-lymph-node-dissection-a-comparison-of-bep%C3%A2-%C3%A3-3-vs-ep%C3%A2-%C3%A3-4-and-treating-institution
#4
Clint Cary, Joseph M Jacob, Costantine Albany, Timothy A Masterson, Nasser H Hanna, Lawrence H Einhorn, Richard S Foster
BACKGROUND: Patients with International Germ Cell Cancer Collaborative Group (IGCCCG) good-risk testicular cancer might receive either 4 cycles of etoposide and cisplatin (EP × 4) or 3 cycles of bleomycin, etoposide, and cisplatin (BEP × 3). We sought to examine differences in survival after retroperitoneal lymph node dissection (PC-RPLND) between patients who received EP × 4 compared with BEP × 3. PATIENTS AND METHODS: The Indiana University Testis Cancer database was queried to identify IGCCCG good-risk PC-RPLND patients who received either EP × 4 or BEP × 3 induction chemotherapy...
October 16, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/29026972/retroperitoneal-lymph-node-dissection-for-testicular-seminomas-population-based-practice-and-survival-outcomes
#5
Hiten D Patel, Gregory A Joice, Zeyad R Schwen, Alice Semerjian, Ridwan Alam, Arnav Srivastava, Mohamad E Allaf, Phillip M Pierorazio
PURPOSE: While retroperitoneal lymph node dissection (RPLND) is traditionally reserved for nonseminomatous germ cell tumors, recent efforts to reduce long-term toxicities of radiation and chemotherapy have turned attention to its application for testicular seminomas. Currently, RPLND is reserved for the post-chemotherapy for stage II testicular seminomas; we aimed to describe current utilization of RPNLD for testicular seminomas by stage and implications for survival. METHODS: A national sample of men diagnosed with stage IA/IB/IS/IIA/IIB/IIC testicular seminoma (1988-2013) was evaluated from SEER Program registries...
October 12, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/29021655/robot-assisted-retroperitoneal-lymph-node-dissection-feasibility-and-outcome-in-postchemotherapy-residual-mass-in-testicular-cancer
#6
Amitabh Singh, Smaranjit Chatterjee, Prashant Bansal, Abhishek Bansal, Sudhir Rawal
INTRODUCTION: We aimed to evaluate the surgical feasibility, complication, and oncological outcome of robot-assisted retroperitoneal lymph node dissection (RA-RPLND) in patients of testicular tumor with postchemotherapy residual retroperitoneal mass. METHODS: A total of 13 patients underwent RA-RPLND between January 2012 and September 2016 at our institute. A study was started on December 2015, so data were collected retrospectively and prospectively regarding patient demography, tumor characteristics, surgical, pathological outcome, and oncological outcome...
October 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28964782/laparoscopic-retroperitoneal-lymph-node-dissection-l-rplnd-in-clinical-stage-i-non-seminomatous-germ-cell-tumors-of-the-testis-nsgctt-safety-and-efficacy-analyses-in-a-high-volume-center
#7
Nicola Nicolai, Nicholas Tarabelloni, Francesca Gasperoni, Mario Catanzaro, Silvia Stagni, Tullio Torelli, Antonio Tesone, Laura Bettin, Andrea Necchi, Patrizia Giannatempo, Daniele Raggi, Maurizio Colecchia, Luigi Piva, Roberto Salvioni, Anna Maria Paganoni, Giorgio Pizzocaro, Davide Biasoni
PURPOSE: Prognosis of stage I NSGCTT is very favorable. Early and late side effects of treatment may condition quality of life and survival. We determine tolerability, safety and efficacy of L-RPLND in stage I NSGCTT in a high-volume center. PATIENTS AND METHODS: From 2000 and 2014, 225 patients undergoing unilateral L-RPLND were prospectively recorded. Since 2007 patients underwent multidisciplinary clinic and were proposed surgery as an alternative to surveillance or adjuvant chemotherapy...
September 27, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28935185/impact-of-hospital-case-volume-on-testicular-cancer-outcomes-and-practice-patterns
#8
Solomon L Woldu, Justin T Matulay, Timothy N Clinton, Nirmish Singla, Laura-Maria Krabbe, Ryan C Hutchinson, Arthur Sagalowsky, Yair Lotan, Vitaly Margulis, Aditya Bagrodia
BACKGROUND: Given the rarity of testicular germ cell tumors (TGCTs) and the complex aspects of management, we evaluate the effect of hospital TGCT case volume on overall survival outcomes and practice patterns. MATERIALS AND METHODS: The National Cancer Database was queried for patients diagnosed with seminoma or nonseminomatous germ cell tumor (NSGCT). Hospitals were classified by case volume as high (99th percentile, ≥26.1 cases annually), high-intermediate (95-99th percentile, 14...
September 18, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28758272/transoral-robotic-retropharyngeal-node-dissection-in-oropharyngeal-squamous-cell-carcinoma-patterns-of-metastasis-and-functional-outcomes
#9
Scott Troob, Babak Givi, Macgregor Hodgson, Alia Mowery, Neil D Gross, Peter E Andersen, Daniel Clayburgh
BACKGROUND: Assessment of the retropharyngeal lymph nodes is essential in the treatment for oropharyngeal squamous cell carcinoma (SCC). Transoral robotic retropharyngeal lymph node dissection (RPLND) may provide valuable staging information and guide selection of adjuvant therapy in a transoral robotic surgery (TORS) treatment paradigm. METHODS: Outcomes were compared between 30 patients with oropharyngeal SCC with tonsillar primaries undergoing RPLND and 37 stage-matched cases without RPLND...
July 31, 2017: Head & Neck
https://www.readbyqxmd.com/read/28506050/-a-clinicopathologic-study-of-6-patients-with-histologically-pure-seminoma-but-elevated-serum-alpha-fetoprotein
#10
Shuya Kandori, Koji Kawai, Ken Tanaka, Takashi Kawahara, Atsushi Ikeda, Ryutaro Ishitsuka, Tomokazu Kimura, Takahiro Kojima, Akira Joraku, Jun Miyazaki, Hiroyuki Nishiyama
Histologically pure seminoma with elevated alpha-fetoprotein (AFP), so-called AFP-positive seminoma, is rare. It is recommended that patients with AFP-positive seminoma be managed as non-seminoma, but the clinical features and prognosis of this disease are not fully understood. In this study, we retrospectively analyzed 6 cases of metastatic AFP-positive seminoma at Tsukuba University Hospital (TUH). AFP was elevated before induction chemotherapy in 4 patients with an average of 1,372 ng/ml. In the remaining 2 patients, AFP became elevated during or after induction chemotherapy...
April 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/28443239/primitive-neuro-ectodermal-tumor-arising-in-a-testicular-teratoma-with-retroperitoneal-metastasis-a-case-report-and-review-of-literature
#11
Guodong Hu, Andrew Wang, Xiu Wang, Leilei Xia, Benjamin L Taylor, S Buce Malkowicz, Priti Lal, Julia R Maisel
A 38-year-old man presenting with left testicular mass and extensive retroperitoneal lymphadenopathy underwent radical orchiectomy and specimen showed a germ cell tumor of primarily primitive neuroectodermal tumor mixed with mature teratoma. He then underwent RPLND, followed by adjuvant CAV (cyclophosphamide, doxorubicin, vincristine) and IE (ifosfamide, etoposide) alternating chemotherapy given the high rate of recurrence and high rate of response to the PNET-specific chemotherapy.
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28325537/midline-extraperitoneal-approach-to-retroperitoneal-lymph-node-dissection-in-testicular-cancer-minimizing-surgical-morbidity
#12
Sumeet Syan-Bhanvadia, Soroush T Bazargani, Thomas G Clifford, Jie Cai, Gus Miranda, Siamak Daneshmand
BACKGROUND: Retroperitoneal lymph node dissection (RPLND) is an important component of the management of testicular germ cell tumor (GCT) but carries significant surgical morbidity. OBJECTIVE: To describe our experience with a midline extraperitoneal (EP) approach to RPLND for seminomatous and nonseminomatous GCT. DESIGN, SETTING, AND PARTICIPANTS: From 2010 to 2015, 122 consecutive patients underwent RPLND from a prospective database. Patients requiring aortic resection or retrocrural dissection or with intraperitoneal disease were excluded...
November 2017: European Urology
https://www.readbyqxmd.com/read/28296054/modified-retroperitoneal-lymph-node-dissection-for-post-chemotherapy-residual-tumour-a-long-term-update
#13
Jane S Cho, Hristos Z Kaimakliotis, Clint Cary, Timothy A Masterson, Stephen Beck, Richard Foster
OBJECTIVE: To update previously reported outcomes of modified-template post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND) in appropriately selected patients with metastatic non-seminomatous germ cell tumour (NSGCT), as our previous report was criticised for short follow-up and so we now provide a long-term update on this cohort. PATIENTS AND METHODS: In all, 100 patients with normal serum markers after cisplatin-based chemotherapy and residual retroperitoneal tumour underwent modified PC-RPLND between 1991 and 2004...
July 2017: BJU International
https://www.readbyqxmd.com/read/28262537/robot-assisted-retroperitoneal-lymph-node-dissection-ra-rplnd-in-the-adolescent-population
#14
A P Glaser, D K Bowen, B W Lindgren, J J Meeks
BACKGROUND: Robot-assisted retroperitoneal lymph node dissection (RA-RPLND) has built on success and techniques of laparoscopic RPLND, with the added benefits of robotic technology. This paper demonstrates use of the da Vinci Xi(®) system for RA-RPLND in two adolescent patients. METHODS: Case #1: A 17-year-old male presented with a left testicular mass and elevated alpha-fetoprotein (AFP) and human chorionic gonadotropin (HCG). Pathology revealed a mixed non-seminomatous germ cell tumor (60% embryonal, 35% yolk sac, 5% choriocarcinoma, + lymphovascular invasion)...
February 17, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28150168/retroperitoneal-lymph-node-dissection-an-update-in-testicular-malignancies
#15
REVIEW
K Yadav
Management of testicular cancer has evolved through many breakthroughs. The decades of zeal to improve oncologic adequacy and to decrease morbidity has led to the current scientific knowledge of retroperitoneal lymph node dissection templates. Retroperitoneal lymph node dissection (RPLND) has potential for staging, prognostication and therapeutic importance in the management of testicular malignancy. RPLND has overcome limitations of current imaging which understage 30% of stage I disease and overstage 25-30% of stage II disease...
July 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/28124545/robot-assisted-laparoscopic-retroperitoneal-lymph-node-dissection-in-testicular-tumor
#16
Fabio C M Torricelli, Denis Jardim, Giuliano B Guglielmetti, Vipul Patel, Rafael F Coelho
INTRODUCTION AND OBJECTIVE: Retroperitoneal lymph node dissection (RPLND) is indicated for patients with non-seminomatous germ cell tumor (NSGCT) with residual disease after chemotherapy. Although the gold standard approach is still the open surgery, few cases of robot-assisted laparoscopic RPLND have been described. Herein, we aim to present the surgical technique for robot-assisted laparoscopic RPLND. PATIENT AND METHOD: A 30 year-old asymptomatic man presented with left testicular swelling for 2 months...
January 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27981731/robotic-salvage-retroperitoneal-and-pelvic-lymph-node-dissection-for-node-only-recurrent-prostate-cancer-technique-and-initial-series
#17
Andre Abreu, Carlos Fay, Daniel Park, David Quinn, Tanya Dorff, John Carpten, Peter Kuhn, Parkash Gill, Fabio Almeida, Inderbir Gill
OBJECTIVES: To describe the technique of robot-assisted high-extended salvage retroperitoneal and pelvic lymphadenectomy (sRPLND+PLND) for 'node-only' recurrent prostate cancer. PATIENTS AND METHODS: In all, 10 patients underwent robot-assisted sRPLND+PLND (09/2015-03/2016) for 'node-only' recurrent prostate cancer, as identified by (11) C-acetate positron emission tomography/computed tomography imaging. Our anatomical template extends from bilateral renal artery/vein cranially up to Cloquet's node caudally, completely excising lymphatic-fatty tissue from aorto-caval and iliac vascular trees; RPLND precedes PLND...
September 2017: BJU International
https://www.readbyqxmd.com/read/27909618/clinico-pathological-outcomes-of-post-primary-and-salvage-chemotherapy-retroperitoneal-lymph-node-dissection-for-mixed-germ-cell-tumors-king-hussein-cancer-center-experience
#18
Kholoud Alqasem, Ibrahim Abukhiran, Judy Jasser, Tamer Bisharat, Riyad T Ellati, Jakub Khzouz, Ibrahim Al-Saidi, Ali Al-Daghamin
OBJECTIVE: We sought to characterize clinical and pathologic outcomes of advanced mixed germ cell tumors after retroperitoneal lymph node dissection for post-chemotherapy residual masses. MATERIAL AND METHODS: Between January 2006 and November 2015, 56 patients underwent retroperitoneal lymph node dissection (RPLND) for residual masses of greater than 1 cm after receiving either primary chemotherapy or salvage chemotherapy. Retrospective review of the patients' characteristics, clinical, pathological, and treatment outcomes were performed after institutional review board (IRB) and ethics committee approval...
December 2016: Turkish Journal of Urology
https://www.readbyqxmd.com/read/27879966/andrological-complications-following-retroperitoneal-lymph-node-dissection-for-testicular-cancer
#19
REVIEW
Alessandro Crestani, Francesco Esperto, Marta Rossanese, Gianluca Giannarini, Nicola Nicolai, Vincenzo Ficarra
Retroperitoneal lymph node dissection (RPLND) is a fundamental surgical step in the treatment of testicular cancer. Nowadays, primary RPLND has partially lost its role in favour of active surveillance (for low risk stage I disease) and short cycle chemotherapy in non-seminomatous germ cell tumor (NSGCT). Conversely, post-chemotherapy RPLND (PC-RPLND) remains the standard treatment for residual masses after chemotherapy. In consideration of curability rate of testicular cancer and the life expectancy of testicular cancer survivors the identification and the prevention of andrological complications became fundamental...
June 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/27878048/validation-of-a-prediction-model-for-avoiding-post-chemotherapy-retroperitoneal-lymphadenectomy-in-patients-with-metastatic-nonseminomatous-germ-cell-cancer
#20
Nahid Punjani, Nicholas Power, James J Vanhie, Eric Winquist
INTRODUCTION: Post-chemotherapy residual masses (PCRMs) may contain persistent cancer or teratoma in more than 50% of patients with metastatic non-seminomatous germ cell tumours (mNSGCTs). Retroperitoneal lymph node dissection (RPLND) is curative, but controversy exists about selection criteria for surgery. A validated prediction model by Vergouwe et al (2007) based on over 1000 patients was evaluated at our centre. METHODS: mNSGCT patients treated with RPLND for PCRMs were identified from an electronic database...
August 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
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