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https://www.readbyqxmd.com/read/29048917/a-population-based-study-of-the-prevalence-of-abnormal-uterine-bleeding-and-its-related-factors-among-iranian-reproductive-age-women-an-updated-data
#1
Hadigheh Kazemijaliseh, Fahimeh Ramezani Tehrani, Samira Behboudi-Gandevani, Davood Khalili, Farhad Hosseinpanah, Fereidoun Azizi
BACKGROUND: Abnormal uterine bleeding (AUB) is one of the most common gynecologic complaints among reproductive-age women. The purpose of this study was to investigate the prevalence of AUB and its related factors among reproductive age Iranian women. METHODS: A population-based cross-sectional study was conducted on 1393 women aged 15 - 45 years who participated in the Tehran Lipid and Glucose Study in 2009 - 2012. FIGO terminology and previous definitions were used for classification of AUB...
September 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/29038072/amenorrhea-rates-and-predictors-during-one-year-of-levonorgestrel-52mg-intrauterine-system-use
#2
Philip D Darney, Gretchen S Stuart, Michael A Thomas, Carrie Cwiak, Andrea Olariu, Mitchell D Creinin
OBJECTIVE: Evaluate amenorrhea patterns and predictors of amenorrhea during the first year after levonorgestrel 52mg intrauterine system (IUS) placement. STUDY DESIGN: This cohort analysis includes 1714 nulliparous and parous women who received a Liletta® levonorgestrel 52mg IUS in a multicenter trial to evaluate efficacy and safety for up to 8years. Participants maintained a daily diary with bleeding information. We assessed bleeding patterns in 90-day intervals; amenorrhea was defined as no bleeding or spotting in the preceding 90days...
October 13, 2017: Contraception
https://www.readbyqxmd.com/read/29030160/mobile-application-vs-paper-pictorial-blood-assessment-chart-to-track-menses-in-young-women-a-randomized-cross-over-design
#3
Amanda E Jacobson, Sara K Vesely, Fareeda Haamid, Myra Christian-Rancy, Sarah H O'Brien
BACKGROUND: /Objectives: Heavy menstrual bleeding is a common complaint reported by approximately 30% of women. The Pictorial Blood Assessment Chart (PBAC) score is often used to quantify severity of menstrual bleeding. However, the traditional PBAC paper diary may be subject to recall bias and compliance issues, especially in adolescents. We developed a mobile application (app) version of the PBAC score and evaluated patient satisfaction and compliance with app reporting vs paper reporting...
October 10, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28984905/meta-analysis-of-bipolar-radiofrequency-endometrial-ablation-versus-thermal-balloon-endometrial-ablation-for-the-treatment-of-heavy-menstrual-bleeding
#4
REVIEW
Yan Zhai, Zihan Zhang, Wei Wang, Tingping Zheng, Huili Zhang
BACKGROUND: Heavy menstrual bleeding is a common problem that can severely affect quality of life. OBJECTIVES: To compare bipolar radiofrequency endometrial ablation and thermal balloon ablation for heavy menstrual bleeding in terms of efficacy and health-related quality of life (HRQoL). SEARCH STRATEGY: Online registries were systematically searched using relevant terms without language restriction from inception to November 24, 2016. SELECTION CRITERIA: Randomized control trials or cohort studies of women with heavy menstrual bleeding comparing the efficacy of two treatments were eligible...
October 6, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28983163/angioleiomyoma-of-uterus-masquerading-as-malignant-ovarian-tumor
#5
Sweta Singh, Monalisha Naik, Narbadyswari Deep Bag, Susama Patra
Uterine angioleiomyoma is rare. A 40-year-old nulliparous woman presented with heavy menstrual bleeding (HMB) for the past 2 years and mass per abdomen with severe dysmenorrhea for three cycles. She had received 8 units of packed cell transfusion outside. Clinical examination revealed a huge 32-week-sized abdominopelvic mass with irregular margins. Ultrasonography (USG) of the abdomen and pelvis showed a large solid cystic mass on the right side of the abdomen with a well-defined hypoechoeic rounded lesion of size 5...
July 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28951427/an-unexpected-complication-following-uterine-artery-embolisation
#6
Sarah Peters, Michelle Wise, Brendan Buckley
A 35-year-old nulliparous woman underwent uterine artery embolisation (UAE) for heavy menstrual bleeding and anaemia due to fibroids, refractive to medical and surgical treatment.Bilateral UAE was performed after cephazolin prophylaxis and analgesia. Postoperatively, pain and abdominal bloating were prominent. Symptoms were initially treated as postembolisation syndrome, and analgesia was escalated. By the third day, pain was worsening and the woman developed marked tachypnoea and tachycardia, with raised inflammatory markers and lactate...
September 26, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28939480/title-hysteroscopic-removal-of-retained-products-of-conception-implanted-over-a-focal-area-of-adenomyosis-a-case-report
#7
Luis Alonso, Laura Nieto, Jose Carugno
STUDY OBJECTIVE: To describe a technique for hysteroscopic removal of retained products of conception (RPOC) implanted over an area of adenomyosis. DESIGN: Case report (Canadian Task Force classification III) SETTING: Retained products of conception is an unfortunate complication that may occur after resolution of a normal pregnancy, being more common after early pregnancy termination or spontaneous miscarriage. (1) Immediate consequences of RPOC include persistent vaginal bleeding, abdominal pain, pelvic infection, fever and dilated cervix...
September 19, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28910998/abnormal-uterine-bleeding
#8
Ying Cheong, Iain T Cameron, Hilary O D Critchley
Introduction: It is not uncommon for a woman to suffer from abnormal uterine bleeding (AUB) or heavy menstrual bleeding (HMB) at some point during her lifetime. Once pathology is excluded, in practice, management needs to be individualised, taking into account the improvement of the woman's symptoms and quality of life. Sources of data: Peer-reviewed journals, governmental and professional society publications. Areas of agreement: There is now agreement on a structured, universal approach to the diagnosis of AUB, with the aide memoirs PALM (polyps, adenomyosis, leiomyoma, malignancy) and COEIN (coagulopathies, ovulatory dysfunction, endometrial, iatrogenic, not otherwise classified)...
September 1, 2017: British Medical Bulletin
https://www.readbyqxmd.com/read/28888699/endometrial-ablation-a-review-article
#9
REVIEW
Abimbola Famuyide
The destruction of the endometrium in women with heavy menstrual bleeding has been employed for well over a century and the various techniques of delivering forms of thermal energy have been modified over the years to assure a safe and effective treatment approach. Today, six non-resectoscopic devices are approved for use in the United States in addition to resectoscopic techniques that rely on skillful use of the operative hysteroscope. Regardless of the technique employed, endometrial ablation uniformly reduces menstrual blood loss, improves general and menstrual related quality of life and prevents hysterectomy in four out of five women who undergo the procedure...
September 6, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28873279/differences-in-bleeding-phenotype-and-provider-interventions-in-postmenarchal-adolescents-when-compared-to-adult-women-with-bleeding-disorders-and-heavy-menstrual-bleeding
#10
L V Srivaths, Q C Zhang, V R Byams, J E Dietrich, A H James, P A Kouides, R Kulkarni
INTRODUCTION: Due to lack of patient/health care provider awareness causing delayed diagnosis, the bleeding phenotype and provider interventions in adolescents with heavy menstrual bleeding (HMB) and bleeding disorders (BD) may be different when compared to adults. AIM: The aim of this study was to compare/characterize bleeding phenotype and provider interventions in postmenarchal adolescents < 18 years and premenopausal adults ≥ 18 years with HMB and BD...
September 5, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28866121/focus-on-uterine-fibroids-evolving-options-to-optimize-care
#11
Sukhbir Sony Singh, Erica E Marsh
No abstract text is available yet for this article.
September 1, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28865555/versatility-of-the-suprapubic-port%C3%A2-in%C3%A2-robotic-assisted-laparoscopic-myomectomy
#12
Ndeye-Aicha Gueye, Linnea R Goodman, Tommaso Falcone
OBJECTIVE: To demonstrate the multiple advantages of the suprapubic port in robotic assisted laparoscopic myomectomy. DESIGN: Video demonstration of a robotic assisted laparoscopic myomectomy technique using a suprapubic incisional retractor (GelPOINT). SETTING: Hospital. PATIENT(S): A 32-year-old primigravid women with heavy menstrual bleeding and pelvic pain with a 12-cm leiomyoma (International Federation of Gynecology and Obstetrics type 5)...
September 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28858896/evaluation-and-management-of-heavy-menstrual-bleeding-in-adolescents
#13
Lisa M Moon, Gisselle Perez-Milicua, Jennifer E Dietrich
PURPOSE OF REVIEW: Heavy menstrual bleeding (HMB) is a common condition in women of reproductive age; however, adolescents with this issue present unique challenges in both diagnosis and management. Much of the research into this topic focuses on the adult population, with variable applicability to adolescents. There are currently no standard guidelines for the work up and treatment of adolescents with HMB. RECENT FINDINGS: Current research into this topic has explored the utilization of standardized protocols in the evaluation of HMB in adolescents, the efficacy of various hormonal, nonhormonal, and surgical treatment modalities, and the benefits of a multidisciplinary approach...
October 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28826369/literature-review-on-the-role-of-uterine-fibroids-in-endometrial-function
#14
Deborah E Ikhena, Serdar E Bulun
Uterine fibroids are benign uterine smooth muscle tumors that are present in up to 8 out of 10 women by the age of 50. Many of these women experience symptoms such as heavy and irregular menstrual bleeding, early pregnancy loss, and infertility. Traditionally believed to be inert masses, fibroids are now known to influence endometrial function at the molecular level. We present a comprehensive review of published studies on the effect of uterine fibroids on endometrial function. Our goal was to explore the current knowledge about how uterine fibroids interact with the endometrium and how these interactions influence clinical symptoms...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28815060/defective-expression-of-atg4d-abrogates-autophagy-and-promotes-growth-in-human-uterine-fibroids
#15
Abdeljabar El Andaloussi, Samar Habib, Gizem Soylemes, Archana Laknaur, Heba Elhusseini, Ayman Al-Hendy, Nahed Ismail
Uterine fibroids (UF) are the most common pelvic tumors in women of reproductive-age and they usually cause heavy menstrual bleeding, pain and infertility. Autophagy is a collection of processes that enables the cells to digest and recycle their cytoplasmic contents, such as toxic protein aggregates, defunct or disused organelles and invading microorganisms. Dysregulation in autophagy process were described in neoplasms; however, the contribution of autophagy to the pathogenesis of UF remains unknown. In this study, we demonstrate that autophagy is deregulated in human UF as evidenced by significant accumulation of autophagosome in human UF cells compared to normal myometrium cells...
2017: Cell Death Discovery
https://www.readbyqxmd.com/read/28796898/comparison-of-the-levonorgestrel-releasing-intrauterine-system-hysterectomy-and-endometrial-ablation-for-heavy-menstrual-bleeding-in-a-decision-analysis-model
#16
REVIEW
Michelle Louie, Jennifer Spencer, Stephanie Wheeler, Victoria Ellis, Tarek Toubia, Lauren D Schiff, Matthew T Siedhoff, Janelle K Moulder
BACKGROUND: A better understanding of the relative risks and benefits of common treatment options for abnormal uterine bleeding (AUB) can help providers and patients to make balanced, evidence-based decisions. OBJECTIVES: To provide comparative estimates of clinical outcomes after placement of levonorgestrel-releasing intrauterine system (LNG-IUS), ablation, or hysterectomy for AUB. SEARCH STRATEGY: A PubMED search was done using combinations of search terms related to abnormal uterine bleeding, LNG-IUS, hysterectomy, endometrial ablation, cost-benefit analysis, cost-effectiveness, and quality-adjusted life years...
August 10, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28790785/a-randomized-control-trial-to-assess-efficacy-of-mifepristone-in-medical-management-of-uterine-fibroid
#17
D Arora, Jaya Chawla, S P S Kochar, J C Sharma
BACKGROUND: Fibroids are the most common benign tumours of uterus. Heavy menstrual bleeding is the commonest concern for which medical attention is sought. Hysterectomies for leiomyoma constitute a third of all hysterectomies. Thus, healthcare cost to society due to uterine leiomyomas is of considerable importance. METHODS: A prospective study was conducted at tertiary care hospital of armed forces. 120 women in pre-menopausal age group with complaints of menorrhagia, Pictorial Bleeding Assessment Chart (PBAC) scoring ≥100 and at least one fibroid ≥2...
July 2017: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28754438/cost-effectiveness-of-treatments-for-heavy-menstrual%C3%A2-bleeding
#18
Jennifer C Spencer, Michelle Louie, Janelle K Moulder, Victoria Ellis, Lauren D Schiff, Tarek Toubia, Matthew T Siedhoff, Stephanie B Wheeler
BACKGROUND: Heavy menstrual bleeding affects up to one third of women in the United States, resulting in a reduced quality of life and significant cost to the health care system. Multiple treatment options exist, offering different potential for symptom control at highly variable initial costs, but the relative value of these treatment options is unknown. OBJECTIVE: The objective of the study was to evaluate the relative cost-effectiveness of 4 treatment options for heavy menstrual bleeding: hysterectomy, resectoscopic endometrial ablation, nonresectoscopic endometrial ablation, and the levonorgestrel-releasing intrauterine system...
July 25, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28734829/feasibility-of-prophylactic-salpingectomy-during-vaginal%C3%A2-hysterectomy
#19
Danielle D Antosh, Rachel High, Heidi W Brown, Sallie S Oliphant, Husam Abed, Nisha Philip, Cara L Grimes
BACKGROUND: The American Congress of Obstetricians and Gynecologists recommends that "the surgeon and patient discuss the potential benefits of the removal of the fallopian tubes during a hysterectomy in women at population risk of ovarian cancer who are not having an oophorectomy," resulting in an increasing rate of salpingectomy at the time of hysterectomy. Rates of salpingectomy are highest for laparoscopic and lowest for vaginal hysterectomy. OBJECTIVE: The primary objective of this study was to determine the feasibility of bilateral salpingectomy at the time of vaginal hysterectomy...
July 20, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28696501/long-term-incidence-of-hysterectomy-following-endometrial-resection-or-endometrial-ablation-for-heavy-menstrual-bleeding
#20
Emmanouil Kalampokas, Sarah McRobbie, Fiona Payne, David E Parkin
OBJECTIVE: To estimate the incidence of hysterectomy following endometrial resection or endometrial ablation (ERA). METHODS: The present retrospective study enrolled women who underwent ERA for benign heavy menstrual bleeding (HMB) at Aberdeen Royal Infirmary, UK, between February 1, 1990, and December 31, 1997; follow-up data to the end of 2015 were included from the pathology laboratory report system from the single pathology laboratory in the region. Data were compared between patients who did or did not require a hysterectomy after ERA...
October 2017: International Journal of Gynaecology and Obstetrics
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