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refractive errors in premature infants

Ann Hellström, Karin Källén, Birgitta Carlsson, Gerd Holmström, Peter Jakobsson, Pia Lundgren, Fredrik Serenius, Karin Stjernqvist, Kristina Tornqvist, Kerstin Hellgren
AIM: This study evaluated the contributions of various prenatal and postnatal predictive factors to a documented high prevalence of ophthalmological abnormalities in children aged 6.5 years who were born extremely preterm. METHODS: We carried out a prospective population-based study of all children born in Sweden at a gestational age of 22 + 0 to 26 + 6 weeks based on the Extremely Preterm Infants in Sweden Study. The main outcome measures were a combined score of visual impairment, refractive errors and strabismus at 6...
December 27, 2017: Acta Paediatrica
Achim Fieß, Ruth Kölb-Keerl, Alexander K Schuster, Markus Knuf, Bernd Kirchhof, Philipp S Muether, Jacqueline Bauer
BACKGROUND: Limited data exist collating most of the associated factors for strabismus in one analysis. The aim of this study was to assess the prevalence of strabismus and to analyse associated factors in former preterm and full-term infants. METHODS: In this cross-sectional study, 239 former preterm infants with gestational age (GA) ≤ 32 weeks and 264 former full-term born infants with GA ≥ 37 weeks underwent detailed ophthalmologic examination in the age of 4-10 years and perinatal data assessment for risk factor analysis...
December 2, 2017: BMC Ophthalmology
Yi Zha, Guangdong Zhu, Jinfei Zhuang, Haihua Zheng, Jianqiu Cai, Wangqiang Feng
Purpose: To investigate the ocular parameters of premature infants without ROP at gestational age (GA) more than 28 weeks and their relationship with growth parameters. Methods: 76 preterm infants without ROP and 65 term infants were involved to undergo portable slit lamp, RetCam3, ultrasonic A-scan biometry, and cycloplegic streak examination at their 40 weeks' postconceptional ages (PCA). Ocular parameters of infants' right eye and growth parameters were used for analysis...
2017: Journal of Ophthalmology
Levent Korkmaz, Cagatay Karaca, Mustafa Ali Akin, Osman Bastug, Mustafa Sahiner, Ahmet Ozdemir, Tamer Gunes, Mehmet Adnan Ozturk, Selim Kurtoglu
PURPOSE: Retinopathy of prematurity (ROP) is one of the major problems of surviving premature infants with several ophthalmic morbidities such as increased risk of refractive errors, strabismus, and cortical visual impairment. Use of propranolol hydrochloride (PH) for the prevention of ROP is a new promising treatment modality. However, long-term effects are still to be defined. In our study, we aimed to investigate the short-term refractive effects of PH used for ROP prophylaxis in very preterm newborns...
February 2018: Current Eye Research
Anna L Ells, Jason D Wesolosky, April D Ingram, Patrick C Mitchell, Alexander S Platt
OBJECTIVE: The aim of this study was to evaluate the visual and structural outcomes of eyes that received ranibizumab as treatment for retinopathy of prematurity (ROP). METHODS: This was a retrospective case series of infants who received a 0.2 mg (0.02 mL) intravitreal injection of ranibizumab as the primary treatment for type 1 ROP. Outcome measures included regression or recurrence of ROP, complications of treatment, and assessment of visual acuity and refractive error...
October 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Samir Uprety, Priya Morjaria, Jyoti B Shrestha, Gauri S Shrestha, Safal Khanal
SIGNIFICANCE: This study suggests that pre-term infants, even without retinopathy of prematurity, are at risk for abnormal refractive development and informs the need for close monitoring of refractive error in such infants, regardless of their retinopathy of prematurity status. PURPOSE: The present study aims to investigate the refractive error trend in Nepalese pre-term infants without retinopathy of prematurity (ROP) in the first 6 months of life and explore the association of refractive error with birth weight (BW) and gestational age (GA)...
October 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
Florina Stoica, Corina Ladariu, Marie-Jeanne Koos, Alina Stanciu, Gabriela Olariu, Nicoleta Andreescu, Maria Puiu
OBJECTIVES: The aim of this study is to assess the functional outcomes registered in patients from the Western part of Romania, who have been treated for retinopathy of prematurity, using a laser diode (810mn). MATERIALS AND METHODS: In the current study 52 premature infants with gestational age<34 weeks and a birth weight <2000 grams, 96 eyes in total were included. The functional outcomes were assessed by determining the best corrected visual acuity and refractive error...
June 2016: Mædica
Emrah Utku Kabataş, Bengi Ece Kurtul, Pınar Altıaylık Özer, Naciye Kabataş
PURPOSE: To evaluate effectiveness of treatment modalities, major complications and refractive errors in children who were treated with intravitreal bevacizumab (IVB), intravitreal ranibizumab (IVR) or laser photocoagulation (LP) for type 1 retinopathy of prematurity (ROP). METHODS: Premature infants who underwent IVB monotherapy (Group 1), IVR monotherapy (Group 2) or LP (Group 3) for type 1 ROP and infants with spontaneously regressed ROP (Group 4) were included for the study...
January 27, 2017: Current Eye Research
Julie Y C Lok, Wilson W K Yip, Abbie S W Luk, Joyce K Y Chin, Henry H W Lau, Alvin L Young
PURPOSE: To report the visual outcome and refractive status in first 3 years of age in preterm infants suffered from laser-treated Type 1 retinopathy of prematurity (ROP): a 6-year review in Hong Kong DESIGN: Retrospective case series METHODOLOGY: Clinical records of all infants suffered from Type 1 ROP who had undergone laser therapy between 2007 and 2012 were retrospectively reviewed. Basic demographic data, serial changes of refractive error, visual acuity, severity of ROP and laser were analyzed...
January 4, 2017: International Ophthalmology
N Levy, E S Shinwell, H Leiba
OBJECTIVE: To study the effect of plurality on refractive status in former preterm infants at age 8-12 years. METHODS: Refraction was compared in singletons and multiples, in very low birth weight infants (VLBW, <1500 g) at age 6 months and 8-12 years. Preterm infants were compared with a group of term infants. RESULTS: Thirty-seven of 104 (36%) VLBW infants were multiples. Comparison of refraction between singletons and multiples revealed no difference at age 6 months, while at age 8-12 years, multiples had significantly more refractive errors (singletons 28% versus multiples 54% p = 0...
October 2017: Journal of Maternal-fetal & Neonatal Medicine
Özdemir Özdemir, Zühal Özen Tunay, Damla Ergintürk Acar
BACKGROUND/AIM: To investigate the biometric components and refractive errors in premature infants with or without retinopathy of prematurity (ROP). MATERIALS AND METHODS: Anterior chamber depth, lens thickness, vitreous length, and axial length were measured with an ultrasound biometer. Cycloplegic refraction was performed by streak skiascopy. Infants with or without ROP were grouped according to postmenstrual age at the time of ocular examination: Group 1, ≤33 weeks; Group 2, 34-37 weeks; Group 3, 38-41 weeks; Group 4, 42-45 weeks; Group 5, ≥46 weeks...
February 17, 2016: Turkish Journal of Medical Sciences
Isıl Sayman Muslubas, Murat Karacorlu, Mumin Hocaoglu, Serra Arf, Hakan Ozdemir
PURPOSE: To evaluate the outcomes of transscleral diode laser photocoagulation in the eyes of children with a history of threshold retinopathy of prematurity (ROP) and compare them with the eyes of children with no or subthreshold ROP and normal term infants by spectral-domain optical coherence tomography (SD-OCT). METHODS: Three groups of children aged 4 to 10 years were included as follows: 45 patients with regressed ROP who had not received any treatment (group 1), 48 patients with a history of zone 2 threshold ROP who had been treated with transscleral diode laser (group 2), and 56 age-matched healthy full-term children (group 3)...
March 10, 2017: European Journal of Ophthalmology
Je Moon Yoon, Dong Hoon Shin, Sang Jin Kim, Don-Il Ham, Se Woong Kang, Yun Sil Chang, Won Soon Park
PURPOSE: To investigate the anatomical and refractive outcomes in patients with Type 1 retinopathy of prematurity in Zone I. METHODS: The medical records of 101 eyes of 51 consecutive infants with Type 1 retinopathy of prematurity in Zone I were analyzed. Infants were treated by conventional laser photocoagulation (Group I), combined intravitreal bevacizumab injection and Zone I sparing laser (Group II), or intravitreal bevacizumab with deferred laser treatment (Group III)...
January 2017: Retina
Eren Cerman, Deniz Ozarslan Ozcan, Hande Celiker, Muhsin Eraslan, Ozlem Sahin, Haluk Kazokoglu
AIM: To describe the clinical characteristics and late results of patients with retinopathy of prematurity (ROP) treated with "6h cryotherapy". METHODS: Out of 1252 infants screened for ROP, 52 patients were treated with temporal 6h cryotherapy from 1997 to 2005 were recalled to our clinic. Among these 23 patients were available and 46 eyes of 23 infants were included to evaluate for visual acuity, refractive error, ocular alignment, nystagmus, retinal examination (abnormal branching of retinal vessels, retinal thinning, latis degenerations, tortuosity of vessels, straightening of temporal vessels, narrowing of the angle of vessel in the juxtapapillary entrance, pigment changes, macular heterotopia), optic atrophy and optic disc cupping, axial length at birth and axial length at 1y...
2016: International Journal of Ophthalmology
Murat Gunay, Mehmet Ali Sekeroglu, Handan Bardak, Gokhan Celik, Cenap Mahmut Esenulku, Emre Hekimoglu, Yavuz Bardak
PURPOSE: To assess ocular biometric outcomes following intravitreal bevacizumab (IVB) monotherapy for retinopathy of prematurity (ROP) and compare these results with those of laser photocoagulated infants and with the ones with spontaneously regressed ROP. MATERIALS AND METHODS: Premature infants including those who underwent IVB monotherapy (Group 1) or laser photocoagulation (Group 2) for ROP and infants with spontaneously regressed ROP (Group 3) were recruited for the study...
June 2016: Strabismus
Ramak Roohipoor, Reza Karkhaneh, Mohammad Riazi Esfahani, Fateme Alipour, Mahtab Haghighat, Nazanin Ebrahimiadib, Mohammad Zarei, Ramin Mehrdad
AIM: To compare refractive error changes in retinopathy of prematurity (ROP) patients treated with diode and red lasers. METHODS: A randomized double-masked clinical trial was performed, and infants with threshold or prethreshold type 1 ROP were assigned to red or diode laser groups. Gestational age, birth weight, pretreatment cycloplegic refraction, time of treatment, disease stage, zone and disease severity were recorded. Patients received either red or diode laser treatment and were regularly followed up for retina assessment and refraction...
2016: Ophthalmologica. Journal International D'ophtalmologie
O Ozdemir, Z Ozen Tunay, D Erginturk Acar, U Acar
PURPOSE: To examine refractive errors and refractive development in premature infants. METHODS: Premature infants in the retinopathy of prematurity (ROP) screening program were recruited and examined longitudinally between 28 and 58 weeks postmenstrual age. For performing cycloplegic retinoscopy, 1% tropicamide was administered, two drops with a 10-minute interval, in order to paralyze accommodation and to achieve cycloplegia. Birth weight, gestational age, gender and acute ROP disease were recorded...
December 2015: Journal Français D'ophtalmologie
Murat Gunay, Gokhan Celik, Betul Onal Gunay, Alev Aktas, Guner Karatekin, Fahri Ovali
PURPOSE: To evaluate 2-year outcomes following intravitreal bevacizumab (IVB) as monotherapy for aggressive posterior retinopathy of prematurity (APROP). METHODS: Medical records of 40 infants were retrospectively reviewed. Group I included infants who had received IVB injections for APROP. Group II included infants who underwent laser treatment for APROP. Anatomic and refractive outcomes and the presence of anisometropia and strabismus were assessed at follow-up examinations...
September 2015: Arquivos Brasileiros de Oftalmologia
Phuoc Huu Nguyen, Caroline Catt, Tinh Xuan Nguyen, Van Trong Pham
BACKGROUND: The purpose of this study was to evaluate the refraction of eyes treated with diode laser photocoagulation for prethreshold retinopathy of prematurity (ROP) at a mean of 5 years after treatment. MATERIALS AND METHODS: Fifty infants with prethreshold ROP treated with diode laser at Hanoi Childrens' Hospital during the period 2008 to 2009 were reviewed. Refractive error was identified by cycloplegic refraction with Cyclogyl 1%. Myopia was divided into two categories based on magnitude: high myopia (more than -5...
2015: Clinical Ophthalmology
Sailaja Bondalapati, Ronald W Milam, J Niklas Ulrich, Michelle T Cabrera
BACKGROUND AND OBJECTIVE: To explore characteristics associated with cystoid macular edema (CME) in neonates screened for retinopathy of prematurity (ROP). PATIENTS AND METHODS: In this institutional review board-approved, prospective, observational study, premature neonates underwent imaging with handheld spectral-domain optical coherence tomography. RESULTS: Of 73 included infants (median gestational age [GA]: 28 weeks, range 23-33 weeks; birth weight: 966 g, range 506 g-1695 g), 28 (38%) had CME and 17/28 (61%) had ROP...
September 2015: Ophthalmic Surgery, Lasers & Imaging Retina
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