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refractive errors in premature infants

Emrah Utku Kabataş, Bengi Ece Kurtul, Pınar Altıaylık Özer, Naciye Kabataş
PURPOSE: To evaluate effectiveness of treatment modalities, major complications and refractive errors in children who were treated with intravitreal bevacizumab (IVB), intravitreal ranibizumab (IVR) or laser photocoagulation (LP) for type 1 retinopathy of prematurity (ROP). METHODS: Premature infants who underwent IVB monotherapy (Group 1), IVR monotherapy (Group 2) or LP (Group 3) for type 1 ROP and infants with spontaneously regressed ROP (Group 4) were included for the study...
January 27, 2017: Current Eye Research
Julie Y C Lok, Wilson W K Yip, Abbie S W Luk, Joyce K Y Chin, Henry H W Lau, Alvin L Young
PURPOSE: To report the visual outcome and refractive status in first 3 years of age in preterm infants suffered from laser-treated Type 1 retinopathy of prematurity (ROP): a 6-year review in Hong Kong DESIGN: Retrospective case series METHODOLOGY: Clinical records of all infants suffered from Type 1 ROP who had undergone laser therapy between 2007 and 2012 were retrospectively reviewed. Basic demographic data, serial changes of refractive error, visual acuity, severity of ROP and laser were analyzed...
January 4, 2017: International Ophthalmology
N Levy, E S Shinwell, H Leiba
OBJECTIVE: To study the effect of plurality on refractive status in former preterm infants at age 8-12 years. METHODS: Refraction was compared in singletons and multiples, in very low birth weight infants (VLBW, <1500 g) at age 6 months and 8-12 years. Preterm infants were compared with a group of term infants. RESULTS: Thirty-seven of 104 (36%) VLBW infants were multiples. Comparison of refraction between singletons and multiples revealed no difference at age 6 months, while at age 8-12 years, multiples had significantly more refractive errors (singletons 28% versus multiples 54% p = 0...
October 26, 2016: Journal of Maternal-fetal & Neonatal Medicine
Özdemir Özdemir, Zühal Özen Tunay, Damla Ergintürk Acar
BACKGROUND/AIM: To investigate the biometric components and refractive errors in premature infants with or without retinopathy of prematurity (ROP). MATERIALS AND METHODS: Anterior chamber depth, lens thickness, vitreous length, and axial length were measured with an ultrasound biometer. Cycloplegic refraction was performed by streak skiascopy. Infants with or without ROP were grouped according to postmenstrual age at the time of ocular examination: Group 1, ≤33 weeks; Group 2, 34-37 weeks; Group 3, 38-41 weeks; Group 4, 42-45 weeks; Group 5, ≥46 weeks...
February 17, 2016: Turkish Journal of Medical Sciences
Isıl Sayman Muslubas, Murat Karacorlu, Mumin Hocaoglu, Serra Arf, Hakan Ozdemir
PURPOSE: To evaluate the outcomes of transscleral diode laser photocoagulation in the eyes of children with a history of threshold retinopathy of prematurity (ROP) and compare them with the eyes of children with no or subthreshold ROP and normal term infants by spectral-domain optical coherence tomography (SD-OCT). METHODS: Three groups of children aged 4 to 10 years were included as follows: 45 patients with regressed ROP who had not received any treatment (group 1), 48 patients with a history of zone 2 threshold ROP who had been treated with transscleral diode laser (group 2), and 56 age-matched healthy full-term children (group 3)...
March 10, 2017: European Journal of Ophthalmology
Je Moon Yoon, Dong Hoon Shin, Sang Jin Kim, Don-Il Ham, Se Woong Kang, Yun Sil Chang, Won Soon Park
PURPOSE: To investigate the anatomical and refractive outcomes in patients with Type 1 retinopathy of prematurity in Zone I. METHODS: The medical records of 101 eyes of 51 consecutive infants with Type 1 retinopathy of prematurity in Zone I were analyzed. Infants were treated by conventional laser photocoagulation (Group I), combined intravitreal bevacizumab injection and Zone I sparing laser (Group II), or intravitreal bevacizumab with deferred laser treatment (Group III)...
January 2017: Retina
Eren Cerman, Deniz Ozarslan Ozcan, Hande Celiker, Muhsin Eraslan, Ozlem Sahin, Haluk Kazokoglu
AIM: To describe the clinical characteristics and late results of patients with retinopathy of prematurity (ROP) treated with "6h cryotherapy". METHODS: Out of 1252 infants screened for ROP, 52 patients were treated with temporal 6h cryotherapy from 1997 to 2005 were recalled to our clinic. Among these 23 patients were available and 46 eyes of 23 infants were included to evaluate for visual acuity, refractive error, ocular alignment, nystagmus, retinal examination (abnormal branching of retinal vessels, retinal thinning, latis degenerations, tortuosity of vessels, straightening of temporal vessels, narrowing of the angle of vessel in the juxtapapillary entrance, pigment changes, macular heterotopia), optic atrophy and optic disc cupping, axial length at birth and axial length at 1y...
2016: International Journal of Ophthalmology
Murat Gunay, Mehmet Ali Sekeroglu, Handan Bardak, Gokhan Celik, Cenap Mahmut Esenulku, Emre Hekimoglu, Yavuz Bardak
PURPOSE: To assess ocular biometric outcomes following intravitreal bevacizumab (IVB) monotherapy for retinopathy of prematurity (ROP) and compare these results with those of laser photocoagulated infants and with the ones with spontaneously regressed ROP. MATERIALS AND METHODS: Premature infants including those who underwent IVB monotherapy (Group 1) or laser photocoagulation (Group 2) for ROP and infants with spontaneously regressed ROP (Group 3) were recruited for the study...
June 2016: Strabismus
Ramak Roohipoor, Reza Karkhaneh, Mohammad Riazi Esfahani, Fateme Alipour, Mahtab Haghighat, Nazanin Ebrahimiadib, Mohammad Zarei, Ramin Mehrdad
AIM: To compare refractive error changes in retinopathy of prematurity (ROP) patients treated with diode and red lasers. METHODS: A randomized double-masked clinical trial was performed, and infants with threshold or prethreshold type 1 ROP were assigned to red or diode laser groups. Gestational age, birth weight, pretreatment cycloplegic refraction, time of treatment, disease stage, zone and disease severity were recorded. Patients received either red or diode laser treatment and were regularly followed up for retina assessment and refraction...
2016: Ophthalmologica. Journal International D'ophtalmologie
O Ozdemir, Z Ozen Tunay, D Erginturk Acar, U Acar
PURPOSE: To examine refractive errors and refractive development in premature infants. METHODS: Premature infants in the retinopathy of prematurity (ROP) screening program were recruited and examined longitudinally between 28 and 58 weeks postmenstrual age. For performing cycloplegic retinoscopy, 1% tropicamide was administered, two drops with a 10-minute interval, in order to paralyze accommodation and to achieve cycloplegia. Birth weight, gestational age, gender and acute ROP disease were recorded...
December 2015: Journal Français D'ophtalmologie
Murat Gunay, Gokhan Celik, Betul Onal Gunay, Alev Aktas, Guner Karatekin, Fahri Ovali
PURPOSE: To evaluate 2-year outcomes following intravitreal bevacizumab (IVB) as monotherapy for aggressive posterior retinopathy of prematurity (APROP). METHODS: Medical records of 40 infants were retrospectively reviewed. Group I included infants who had received IVB injections for APROP. Group II included infants who underwent laser treatment for APROP. Anatomic and refractive outcomes and the presence of anisometropia and strabismus were assessed at follow-up examinations...
September 2015: Arquivos Brasileiros de Oftalmologia
Phuoc Huu Nguyen, Caroline Catt, Tinh Xuan Nguyen, Van Trong Pham
BACKGROUND: The purpose of this study was to evaluate the refraction of eyes treated with diode laser photocoagulation for prethreshold retinopathy of prematurity (ROP) at a mean of 5 years after treatment. MATERIALS AND METHODS: Fifty infants with prethreshold ROP treated with diode laser at Hanoi Childrens' Hospital during the period 2008 to 2009 were reviewed. Refractive error was identified by cycloplegic refraction with Cyclogyl 1%. Myopia was divided into two categories based on magnitude: high myopia (more than -5...
2015: Clinical Ophthalmology
Sailaja Bondalapati, Ronald W Milam, J Niklas Ulrich, Michelle T Cabrera
BACKGROUND AND OBJECTIVE: To explore characteristics associated with cystoid macular edema (CME) in neonates screened for retinopathy of prematurity (ROP). PATIENTS AND METHODS: In this institutional review board-approved, prospective, observational study, premature neonates underwent imaging with handheld spectral-domain optical coherence tomography. RESULTS: Of 73 included infants (median gestational age [GA]: 28 weeks, range 23-33 weeks; birth weight: 966 g, range 506 g-1695 g), 28 (38%) had CME and 17/28 (61%) had ROP...
September 2015: Ophthalmic Surgery, Lasers & Imaging Retina
Hsi-Kung Kuo, I-Ting Sun, Mei-Yung Chung, Yi-Hao Chen
PURPOSE: To evaluate the refractive development of premature infants with retinopathy of prematurity (ROP) after treatment with laser photocoagulation or intravitreal injection of bevacizumab (IVB). METHODS: The medical records of patients with ROP treated between 2003 and 2012 who underwent yearly follow-ups were retrospectively reviewed. Patients with residual ROP abnormalities were excluded. The cycloplegic refraction at 3 years of age, assessed using an autorefractometer, was recorded...
2015: Ophthalmologica. Journal International D'ophtalmologie
H C Fledelius, R Bangsgaard, C Slidsborg, M laCour
BACKGROUND AND PURPOSE: Refractometers have gained a foothold in childhood screening for ophthalmic disorders. Given the results of an ophthalmic follow-up of an extremely preterm Danish cohort, the results of the Retinomax autorefractor were further evaluated. MATERIALS AND METHODS: A nationwide cohort of infants born before gestational age 28 weeks (n=178) and 56 term controls were examined at the age of 4 years. Refraction was given as the cycloplegic Retinomax value...
June 2015: Eye
Christopher K Hwang, G Baker Hubbard, Amy K Hutchinson, Scott R Lambert
PURPOSE: To determine the relative effectiveness, major complications, and refractive errors associated with intravitreal bevacizumab (IVB) versus panretinal photocoagulation (PRP) to treat type 1 retinopathy of prematurity (ROP). DESIGN: Retrospective case series. PARTICIPANTS: Consecutive infants with type 1 ROP who received either IVB or PRP and had at least 6 months of follow-up. METHODS: The data from infants treated with either IVB or PRP for type 1 ROP between 2008 and 2012 were recorded from 2 medical centers in Atlanta, Georgia...
May 2015: Ophthalmology
Rafael Iribarren
Individual refractive errors usually change along lifespan. Most children are hyperopic in early life. This hyperopia is usually lost during growth years, leading to emmetropia in adults, but myopia also develops in children during school years or during early adult life. Those subjects who remain emmetropic are prone to have hyperopic shifts in middle life. And even later, at older ages, myopic shifts are developed with nuclear cataract. The eye grows from 15 mm in premature newborns to approximately 24 mm in early adult years, but, in most cases, refractions are maintained stable in a clustered distribution...
July 2015: Progress in Retinal and Eye Research
Abdelrahman G Salman, Aza M Said
PURPOSE: To study the structural, visual and refractive outcomes of intravitreal injection of aflibercept monotherapy in patients with high-risk prethreshold type 1 retinopathy of prematurity (ROP). DESIGN: Prospective nonrandomized interventional case series study. PATIENTS AND METHODS: 1 mg/0.025 ml intravitreal aflibercept was administered for patients with high-risk prethreshold type 1 ROP. The primary outcomes studied were unfavorable structural outcome, unfavorable visual outcome and unfavorable refractive outcome...
2015: Ophthalmic Research
San-Ni Chen, Iebin Lian, Ya-Chi Hwang, Yi-Hsing Chen, Yao-Chung Chang, Kun-Hsien Lee, Chih-Chun Chuang, Wei-Chi Wu
PURPOSE: To compare the effect and the treatment outcomes of bevacizumab and ranibizumab in the treatment of Type 1 retinopathy of prematurity (ROP). METHODS: This was a bicentered retrospective case series performed at institutional referral centers. Seventy-two eyes of 37 patients who had intravitreal injections of either bevacizumab or ranibizumab as the primary treatment for Type 1 ROP were included. Outcomes' measures included regression and recurrence of ROP, the surgical complications, and refractive errors at a corrected age of 1 year...
April 2015: Retina
Murat Gunay, Gokhan Celik, Fahri Ovali, Huseyin Yetik, Alev Aktas, Betul Onal Gunay
The purpose of the study is to evaluate the clinical outcome of laser photocoagulation (LPC) in the treatment of retinopathy of prematurity (ROP) at a referral hospital in Turkey. In this retrospective study, a chart review of infants who underwent LPC for ROP between June 2011 and June 2013 was done. Clinical and demographic characteristics, laser parameters, anatomic, and refractive outcomes were evaluated. Totally 113 infants (202 eyes) were enrolled in the study. Of the 202 eyes, 29 eyes had threshold ROP, 141 eyes had prethreshold ROP, and 32 eyes had aggressive posterior ROP (APROP) at initial interventions...
February 2015: International Ophthalmology
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