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Marta Anna Szychlinska, Paola Castrogiovanni, Francesca Maria Trovato, Houda Nsir, Mokhtar Zarrouk, Debora Lo Furno, Michelino Di Rosa, Rosa Imbesi, Giuseppe Musumeci
PURPOSE: Osteoarthitis (OA) leads to progressive loss of articular cartilage, pain and joint disability. An acute injury constitutes an important risk factor for early OA, determining an inflammatory process responsible of cartilage degeneration and muscle atrophy, due to the joint pain and immobility. The study aims to assess the effects of conjugation of physical activity and diet enriched by olive tree compounds [extra virgin olive oil (EVOO) and olive leaf extract (OLE)], on the musculoskeletal system in OA rat model...
February 15, 2018: European Journal of Nutrition
Emma Altobelli, Paolo Matteo Angeletti, Domenico Piccolo, Rossella De Angelis
BACKGROUND: The aim of this review is to investigate systematically the presence of the most extensively studied Synovial Fluid (SF) and/or serum markers in patients with Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA) and Osteoarthritis (OA), and their associations and correlations with laboratory and clinical data, with a view to providing insights for future research. OBJECTIVE: Papers were selected using the PRISMA flow-chart. Search of the electronic databases according to the above criteria found a total of 55 papers...
2017: Current Rheumatology Reviews
Hassan Bassiouni, Hany Aly, Khaled Zaky, Nouran Abaza, Thomas Bardin
OBJECTIVE: To compare serum 25 OH vitamin D (25 (OH) D) levels between medial femoro-tibial knee osteoarthritis (OA) patients and controls, and to detect structural progression in patients with mild to moderate knee osteoarthritis in relation to baseline 25(OH) D levels in a oneyear longitudinal prospective cohort study. METHODS: Thirty eight patients with medial femoro-tibial knee OA according to the ACR criteria and no knee malalignement, and 20 age, sex and BMI-matched pain free controls were included in the vitamin D study...
2017: Current Rheumatology Reviews
Antoine de Runz, Nicolas Pauchard, Thomas Sorin, François Dap, Gilles Dautel
BACKGROUND: Ulnocarpal impaction syndrome occurs mostly in patients with positive ulnar variance. Ulnar-shortening osteotomy is a commonly used method to correct it, but degenerative changes may appear in the distal radioulnar joint. The authors evaluated outcome after ulnar-shortening osteotomy, particularly the impact of distal radioulnar joint osteoarthritis. METHODS: A 10-year study was performed of patients who underwent ulnar-shortening osteotomy. RESULTS: Forty-six patients were available for clinical examination and radiography...
January 2016: Plastic and Reconstructive Surgery
Pu Wang, Lin Yang, Chuan Liu, Xiaofei Wei, Xiaotian Yang, Yujing Zhou, Hua Jiang, Zhongjie Lei, Jan D Reinhardt, Chengqi He
OBJECTIVE: To determine effects of Whole Body Vibration Exercise (WBVE) associated with quadriceps resistance exercises (QRE) versus QRE only on pain, physical function, biomarkers in serum and urine, activities of daily living (ADL), and quality of life in patients with knee osteoarthitis (OA). DESIGN: Randomized-controlled trial . SETTING: Rehabilitation medicine outpatient department of West China Hospital, Chengdu, Sichuan, People's Republic of China...
November 2016: Clinical Rehabilitation
A-M Glimm, S G Werner, G R Burmester, M Backhaus, S Ohrndorf
BACKGROUND: In rheumatoid arthritis (RA), hand synovitis appears especially in wrist, metacarpophalangeal (MCP) and proximal interphalangeal (PIP) joints. In hand osteoarthritis (OA), potential inflammatory changes are mainly present in PIP and distal interphalangeal (DIP) joints. Joint inflammation can be visualised by fluorescence optical imaging (FOI) and musculoskeletal ultrasound (US). OBJECTIVE: Comparison of the amount and distribution of inflammatory signs in wrist and finger joints of the clinically dominant hand in patients with OA and RA by FOI and gray-scale (GSUS) and power Doppler US (PDUS)...
March 2016: Annals of the Rheumatic Diseases
Gustavo Constantino De Campos, Marcelo Tomio Kohara, Marcia Uchoa Rezende, Olga Fugiko Magashima Santana, Merilu Marins Moreira, Olavo Pires De Camargo
OBJECTIVE: To evaluate the consistency of the questionnaires (WOMAC, Lequesne, VAS, SF 36-PCS and SF 36-MCS) when applied in patients with osteoarthritis of the knees (KOA) verifying if age and level of education interfere with the completion of the questionnaires. METHOD: One hundred and two patients with KOA answered WOMAC, LESQUESNE, VAS and SF-36 questionnaires and provided data correlated with age and education. The internal consistency of the WOMAC questionnaire was verified with Cronbach's alpha...
2014: Acta Ortopedica Brasileira
M D Crema, M C Nevitt, A Guermazi, D T Felson, K Wang, J A Lynch, M D Marra, J Torner, C E Lewis, F W Roemer
PURPOSE: To determine the association of MRI-assessed worsening of tibiofemoral cartilage damage, meniscal damage, meniscal extrusion, separately and together, with progression of radiographic joint space narrowing (JSN). METHOD AND MATERIALS: The Multicenter Osteoarthitis Study (MOST) Study is a cohort study of subjects with or at risk for knee osteoarthritis (OA). Knees with radiographic OA Kellgren-Lawrence grade 2 at baseline and with baseline and 30-month 1...
October 2014: Osteoarthritis and Cartilage
Alina Beraudi, Monica Montesi, Francesco Traina, Stefano Falcioni, Susanna Stea, Aldo Toni
Osteonectin (ON) is an important matrix glycoprotein highly expressed in bone. In several in vitro and animal model studies, ON was used as indicator of the state of osseointegration of implanted devices. There are, however, no studies on ON expression in the synovial fluid of patients with total hip joint replacement (THJR). The purpose of our study was to determine the ON concentration in synovial fluid from three groups of patients: primary uncemented THJR with hip pain ("pain" group; n = 15) and without pain ("no-pain" group; n = 12), and patients with osteoarthitis scheduled to receive a primary THJR (control group; n = 5)...
June 2013: Artificial Organs
Heng Li, Liqin Li, Jikang Min, Honghang Yang, Xuchun Xu, Yongjian Yuan, Dan Wang
BACKGROUND: The aim of this study was to judge whether there is a correlation between some biochemical features of knee osteoarthritic blood and clinical characteristics and to evaluate the potential relationship between osteoarthitis (OA) severity and putative biomarkers for the disease. METHODS: 105 patients suffering from knee OA were analyzed clinically (Lequesne's index) and radiographically (Kellgren and Lawrence, K&L). Plasma and peripheral blood mononuclear cells (PBMC) were harvested separately...
2012: Clinical Laboratory
Mercedes Fernández-Moreno, Ignacio Rego, Francisco J Blanco
Osteoarthritis is a degenerative articular pathology with complex pathogeny because diverse factors interact causing a process of deterioration of the cartilage. In spite of the multifactorial nature of this pathology, from years 50 one knows that certain forms of osteoarthritis are related to a strong genetic component. The genetic bases of this disease do not follow the typical patterns of mendelian inheritance and probably they are related to alterations in multiple genes. The identification of a high number of candidates genes to confer susceptibility to the development of the osteoarthritis shows the complex nature of this disease...
October 2007: Reumatología Clinica
J-N Goubier, L Devun, D Mitton, F Lavaste
UNLABELLED: First carpometacarpal osteoarthitis is frequent and surgery may be necessary if medical treatment is not efficient. Trapeziometacarpal arthroplasty, trapeziometacarpal arthrodesis and trapezectomy may be proposed. These surgical solutions may modify the carpometacarpal kinematics of the thumb. However, no clinical tools are currently available to assess these modifications. The goal of our study is to assess the TM kinematics, with an optoelectronic system, in patients after trapezectomy...
April 2011: Chirurgie de la Main
P Richette, E Vicaut, M-C de Vernejoul, P Orcel, T Bardin
BACKGROUND: Recent findings that subchondral insufficiency fracture in the femoral head may precede rapid chondrolysis suggest a role for systemic low bone mass in the genesis of rapidly destructive hip osteoarthritis (RDHOA). OBJECTIVE: To compare bone mineral density (BMD) in females with RDHOA and those with common hip osteoarth-ritis (OA). METHODS: This prospective case-control study involved 26 females with RDHOA recruited from our institution between March 2000 and November 2006...
March 2009: Clinical and Experimental Rheumatology
Hansjoerg Heep, Gero Hilken, Sebastian Hofmeister, Christian Wedemeyer
OBJECTIVE: Mechanotransduction is the mechanism that due to reacting chondrocytes on biomechanical loading of body mass. Higher biomechanical loading lead to increased degeneration of chondrocytes, whereas moderate loading is protecting. This suggests that body fat regulates bone metabolism first by means of hormonal factors and second that the effects of muscle and loading are signaling factors in mechanotransduction. Leptin, a peptide hormone produced predominantly by white fat cells, is one of these hormonal factors...
2009: International Journal of Biological Sciences
A Amaro, F Amado, J A Duarte, H-J Appell
In order to understand the role of the GLUTEUS MEDIUS muscle (GM) in hip joint osteoarthritis, the objective of this study was to analyze the correlation between morphometric data of GM samples with osteoarthritis scores of ipsilateral and contralateral hips in 41 patients. GM samples obtained during unilateral hip replacement surgery were used to evaluate muscle fibers in the cross-sectional area (CSA) and other features indicative for muscle aging. Clinical symptoms were assessed by the Lequesne pain score...
December 2007: International Journal of Sports Medicine
Rafał S Filip, Jerzy Bylina, Jerzy Zagórski
Osteoporosis and osteoarthrosis are the most common diseases of bone tissue affecting both rural and urban populations. The aim of the study was to investigate the level of education and requirement for health promotion within the scope of common diseases of the skeletal system among rural population in Poland. This was an exploratory study with a cross-sectional design performed between May 2004-September 2005 in rural areas of 16 Voivodeships (main provinces) of Poland. The study population comprised of 404 (62...
2006: Annals of Agricultural and Environmental Medicine: AAEM
Håkan Ström, Kurt Kolstad, Hans Mallmin, Bo Sahlstedt, Jan Milbrink
BACKGROUND: There is no consensus as to whether uncemented or cemented femoral stems should be used in younger patients. We compared the uncemented Cone stem to the cemented Bimetric stem in young patients with osteoarthritis. PATIENTS AND METHODS: We randomized 45 relatively young patients (< 65 years old, mean age 54 years) with osteoarthritis to either an uncemented Cone stem or a cemented Bimetric stem. All patients were followed for 2 years. Outcome was assessed by the Merle d'Aubigné score, conventional radiography and repeated radio-stereometric analysis (RSA)...
February 2006: Acta Orthopaedica
Catherine M Phan, Thomas M Link, Gabrielle Blumenkrantz, Timothy C Dunn, Michael D Ries, Lynne S Steinbach, Sharmila Majumdar
OBJECTIVE: To assess the rate of cartilage loss, the change in bone marrow edema pattern and internal joint derangement at 1.5-T MRI in patients with knee osteoarthritis and to correlate these findings with the clinical Western Ontario and McMaster University Osteoarthitis (WOMAC) score. METHODS: Forty subjects (mean age 57.7+/-15 years; 16 females and 24 males) were recruited: 6 healthy volunteers (OA0), 17 patients with mild osteoarthritis (OA1) and 17 with severe osteoarthritis (OA2) based on the Kellgren-Lawrence scale...
March 2006: European Radiology
Dieter Grob, Friedrich H Bremerich, Jiri Dvorak, Anne F Mannion
Atlantoaxial (C1-C2) facet joint osteoarthitis is a distinct clinical syndrome that often goes unrecognized. Severe pain resistant to conservative treatment that is corroborated by the radiographic findings represents the indication for surgery. The aim of this study was to retrospectively examine the long-term outcome [after an average 6.5 years (SD 4.0)] of C1-2 fusion for osteoarthritis of the atlantoaxial segment in 35 consecutive patients [25 male, 10 female; aged 62 (SD 15) years]. At follow-up, clinical outcome and radiological status was examined in 27/35 (77%) patients, and self-rated pain and disability (Neck Pain and Disability Scale; NPDS) in 29/35 (83%) patients...
March 2006: European Spine Journal
B Auerbach, C-E Heyde, C Melzer
In this case report we present a 56 years old long standing (20 years) Marathon runner, suffering from chronic groin pain for 1(1/2) year. The great variety of diagnosis, which are subsumed under longstanding groin pain, explain the long time to evaluated the exact diagnosis and to institute a selective therapy. A multidisciplinary investigation was necessary to reveal a bone apposition at insertion of the musculus rectus abdominis in result of a chronic pelvic instability after beginning osteoarthitis and reduced range of rotational motion of the hip...
June 2005: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
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