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high resolution magnetic resonance imaging

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https://www.readbyqxmd.com/read/29160621/magnetic-resonance-imaging-in-heart-failure-including-coronary-imaging-numbers-facts-and-challenges
#1
EDITORIAL
Lisa Adams, Michel Noutsias, Boris Bigalke, Marcus R Makowski
Coronary artery disease (CAD) is a major risk factor for the incidence and progression of heart failure (HF). HF is characterized by a substantial morbidity and mortality and its lifetime risk is estimated at approximately 20% for men and women. As patients are in most cases identified only after developing overt clinical symptoms, detecting early stages of CAD and HF is of paramount importance. Due to its non-invasiveness, excellent soft-tissue contrast, high spatial resolution, and multiparametric nature, cardiovascular magnetic resonance (CMR) imaging has emerged as a promising radiation-free technique to assess a wide range of cardiovascular diseases such as CAD or HF, enabling a comprehensive evaluation of myocardial anatomy, regional and global function, and viability with the additional benefit of in vivo tissue characterization...
November 21, 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/29160415/interregional-correlations-of-glucose-metabolism-between-the-basal-ganglia-and-different-cortical-areas-an-ultra-high-resolution-pet-mri-fusion-study-using-18f-fdg
#2
J H Kim, Y D Son, J M Kim, H K Kim, Y B Kim, C Lee, C H Oh
Basal ganglia have complex functional connections with the cerebral cortex and are involved in motor control, executive functions of the forebrain, such as the planning of movement, and cognitive behaviors based on their connections. The aim of this study was to provide detailed functional correlation patterns between the basal ganglia and cerebral cortex by conducting an interregional correlation analysis of the 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) data based on precise structural information...
November 13, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29159580/low-left-amygdala-volume-is-associated-with-a-longer-duration-of-unipolar-depression
#3
Maxim Zavorotnyy, Rebecca Zöllner, L R Schulte-Güstenberg, L Wulff, S Schöning, U Dannlowski, H Kugel, V Arolt, C Konrad
The amygdala plays a crucial role in the pathogenesis of major depressive disorder (MDD). While robust findings support a negative impact of illness duration on hippocampal volume in MDD, morphometric studies of the amygdala have yielded inhomogeneous results. Considering the methodical problems of automatic segmentation methods, a standardized segmentation protocol with proven inter- and intra-rater reliability was employed using high-resolution magnetic resonance imaging. To identify the effect of MDD on amygdala morphometry, 23 unipolar depressed patients who responded to antidepressant medication and 30 age-matched healthy controls (HC) were enrolled...
November 20, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/29159048/resting-state-connectivity-and-executive-functions-after-pediatric-arterial-ischemic-stroke
#4
Salome Kornfeld, Rui Yuan, Bharat B Biswal, Sebastian Grunt, Sandeep Kamal, Juan Antonio Delgado Rodríguez, Mária Regényi, Roland Wiest, Christian Weisstanner, Claus Kiefer, Maja Steinlin, Regula Everts
Background: The aim of this study was to compare the relationship between core executive functions and frontoparietal network connections at rest between children who had suffered an arterial ischemic stroke and typically developing peers. Methods: Children diagnosed with arterial ischemic stroke more than two years previously and typically developing controls were included. Executive function (EF) measures comprised inhibition (Go-NoGo task), fluency (category fluency task), processing speed (processing speed tasks), divided attention, working memory (letter-number sequencing), conceptual reasoning (matrices) and EF in everyday life (questionnaire)...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29158839/characterization-of-cardiac-dynamics-in-an-acute-myocardial-infarction-model-by-four-dimensional-optoacoustic-and-magnetic-resonance-imaging
#5
Hsiao-Chun Amy Lin, Xosé Luís Déan-Ben, Ivana Ivankovic, Melanie A Kimm, Katja Kosanke, Helena Haas, Reinhard Meier, Fabian Lohöfer, Moritz Wildgruber, Daniel Razansky
Extraction of murine cardiac functional parameters on a beat-by-beat basis is limited with the existing imaging modalities due to insufficient three-dimensional temporal resolution. Faster volumetric imaging methods enabling in vivo characterization of functional parameters are poised to advance cardiovascular research and provide a better understanding of the mechanisms underlying cardiac diseases. We present a new approach based on analyzing contrast-enhanced optoacoustic (OA) images acquired at high volumetric frame rate without using cardiac gating or other approaches for motion correction...
2017: Theranostics
https://www.readbyqxmd.com/read/29158816/dual-targeting-theranostic-system-with-mimicking-apoptosis-to-promote-myocardial-infarction-repair-via-modulation-of-macrophages
#6
Jingli Chen, Jun Yang, Ruiyuan Liu, Chenmeng Qiao, Zhiguo Lu, Yuanjie Shi, Zhanming Fan, Zhenzhong Zhang, Xin Zhang
Currently unsatisfactory treatment of myocardial infarction (MI) is due to the unbridled inflammation and the delayed diagnosis at the early stage. To address these problems, firstly, phosphatidylserine (PS) was used to modulate the phenotypes of macrophages (MΦ) and resolve the early inflammation via binding to PS receptors (PSR) on macrophage surface. Secondly, highly-sensitive magnetic iron oxide nanocubes (MIONs) were adopted to realize the early visualization via magnetic resonance imaging (MRI). However, the major drawback for MIONs as contrast agents was their hydrophobic properties and insufficient delivery...
2017: Theranostics
https://www.readbyqxmd.com/read/29157746/particle-filter-based-target-tracking-algorithm-for-magnetic-resonance-guided-respiratory-compensation-robustness-and-accuracy-assessment
#7
Alexandra E Bourque, Stéphane Bedwani, Jean-François Carrier, Cynthia Ménard, Pim Borman, Clemens Bos, Bas W Raaymakers, Nikolai Mickevicius, Eric Paulson, Rob H N Tijssen
PURPOSE: To assess overall robustness and accuracy of a modified particle filter-based tracking algorithm for magnetic resonance (MR)-guided radiation therapy treatments. METHODS AND MATERIALS: An improved particle filter-based tracking algorithm was implemented, which used a normalized cross-correlation function as the likelihood calculation. With a total of 5 healthy volunteers and 8 patients, the robustness of the algorithm was tested on 24 dynamic magnetic resonance imaging (MRI) time series with varying resolution, contrast, and signal-to-noise ratio...
October 12, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29157260/high-resolution-and-accelerated-multi-parametric-mapping-with-automated-characterization-of-vessel-disease-using-intravascular-mri
#8
Guan Wang, Yi Zhang, Shashank Sathyanarayana Hegde, Paul A Bottomley
BACKGROUND: Atherosclerosis is prevalent in cardiovascular disease, but present imaging modalities have limited capabilities for characterizing lesion stage, progression and response to intervention. This study tests whether intravascular magnetic resonance imaging (IVMRI) measures of relaxation times (T1, T2) and proton density (PD) in a clinical 3 Tesla scanner could characterize vessel disease, and evaluates a practical strategy for accelerated quantification. METHODS: IVMRI was performed in fresh human artery segments and swine vessels in vivo, using fast multi-parametric sequences, 1-2 mm diameter loopless antennae and 200-300 μm resolution...
November 20, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29155081/population-receptive-field-prf-measurements-of-chromatic-responses-in-human-visual-cortex-using-fmri
#9
Lauren E Welbourne, Antony B Morland, Alex R Wade
The spatial sensitivity of the human visual system depends on stimulus color: achromatic gratings can be resolved at relatively high spatial frequencies while sensitivity to isoluminant color contrast tends to be more low-pass. Models of early spatial vision often assume that the receptive field size of pattern-sensitive neurons is correlated with their spatial frequency sensitivity - larger receptive fields are typically associated with lower optimal spatial frequency. A strong prediction of this model is that neurons coding isoluminant chromatic patterns should have, on average, a larger receptive field size than neurons sensitive to achromatic patterns...
November 14, 2017: NeuroImage
https://www.readbyqxmd.com/read/29153326/altered-structural-connectivity-of-the-left-visual-thalamus-in-developmental-dyslexia
#10
Christa Müller-Axt, Alfred Anwander, Katharina von Kriegstein
Developmental dyslexia is a highly prevalent reading disorder affecting about 5%-10% of children [1]. It is characterized by slow and/or inaccurate word recognition skills as well as by poor spelling and decoding abilities [2]. Partly due to technical challenges with investigating subcortical sensory structures, current research on dyslexia in humans by and large focuses on the cerebral cortex [3-7]. These studies found that dyslexia is typically associated with functional and structural alterations of a distributed left-hemispheric cerebral cortex network (e...
November 10, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/29151461/-optical-computed-tomography-for-polymer-gel-dosimetry
#11
Hiraku Kawamura, Takaoki Takanashi, Yoshikazu Shimada, Yuichi Sato, Shinji Abe, Satoshi Hara
This article describes an optical computed tomography (OCT) for polymer gel dosimetry, focusing on two systems recently constructed by us. The first OCT system, which is categorized as a first-generation system, comprised a single He-Ne laser, photodiode, and mechanical stages for moving and turning gel dosimeter. Projection data per angle are acquired from turned gel dosimeter. In this system, the reconstructed image is obtained using filtered back-projection (FBP) method from projection data. The second OCT system is a 2D-OCT scanner that utilizes a light panel and a camera detector...
2017: Japanese Journal of Medical Physics
https://www.readbyqxmd.com/read/29150182/mature-hippocampal-neurons-require-lis1-for-synaptic-integrity-implications-for-cognition
#12
Anamaria Sudarov, Xin-Jun Zhang, Leighton Braunstein, Eve LoCastro, Shawn Singh, Yu Taniguchi, Ashish Raj, Song-Hai Shi, Holly Moore, M Elizabeth Ross
BACKGROUND: Platelet-activating factor acetylhydrolase 1B1 (LIS1), a critical mediator of neuronal migration in developing brain, is expressed throughout life. However, relatively little is known about LIS1 function in the mature brain. We previously demonstrated that LIS1 involvement in the formation and turnover of synaptic protrusions and synapses of young brain after neuronal migration is complete. Here we examine the requirement for LIS1 to maintain hippocampal circuit function in adulthood...
September 23, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/29146731/organic-anion-transporting-polypeptide-1b3-as-a-dual-reporter-gene-for-fluorescence-and-magnetic-resonance-imaging
#13
Menq-Rong Wu, Hon-Man Liu, Chen-Wen Lu, Way-Hone Shen, I-Jou Lin, Li-Wen Liao, Yi-You Huang, Ming-Jium Shieh, Jong-Kai Hsiao
Reporter proteins have broad applications in visualizing molecular events at the cellular, tissue and whole-body levels. Transmembrane transporters recognizing specific molecular domains are of particular interest because they enable the migration of signal-source molecules from the extracellular space to the cytoplasm for subsequent application in multimodality imaging. Organic anion-transporting polypeptides (OATPs) have demonstrated their MRI reporter efficacy. We further expanded their use as a dual-modality reporter in MRI and noninvasive in vivo imaging system (IVIS)...
November 16, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29146377/cortical-processing-of-pitch-model-based-encoding-and-decoding-of-auditory-fmri-responses-to-real-life-sounds
#14
REVIEW
Vittoria De Angelis, Federico De Martino, Michelle Moerel, Roberta Santoro, Lars Hausfeld, Elia Formisano
Pitch is a perceptual attribute related to the fundamental frequency (or periodicity) of a sound. So far, the cortical processing of pitch has been investigated mostly using synthetic sounds. However, the complex harmonic structure of natural sounds may require different mechanisms for the extraction and analysis of pitch. This study investigated the neural representation of pitch in human auditory cortex using model-based encoding and decoding analyses of high field (7 T) functional magnetic resonance imaging (fMRI) data collected while participants listened to a wide range of real-life sounds...
November 13, 2017: NeuroImage
https://www.readbyqxmd.com/read/29144031/error-analysis-of-helmholtz-based-mr-electrical-properties-tomography
#15
Stefano Mandija, Alessandro Sbrizzi, Ulrich Katscher, Peter R Luijten, Cornelis A T van den Berg
PURPOSE: MR electrical properties tomography (MR-EPT) aims to measure tissue electrical properties by computing spatial derivatives of measured B1+ data. This computation is very sensitive to spatial fluctuations caused, for example, by noise and Gibbs ringing. In this work, the error arising from the computation of spatial derivatives using finite difference kernels (FD error) has been investigated. In relation to this FD error, it has also been investigated whether mitigation strategies such as Gibbs ringing correction and Gaussian apodization can be beneficial for conductivity reconstructions...
November 16, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29140527/functional-organization-of-face-processing-in-the-human-superior-temporal-sulcus-a-7t-high-resolution-fmri-study
#16
Anne-Kathrin Schobert, Corrado Corradi-Dell'Acqua, Sascha Frühholz, Wietske van der Zwaag, Patrik Vuilleumier
The superior temporal sulcus (STS) is a major component of the human face perception network, implicated in processing dynamic changeable aspects of faces. However, it remains unknown whether STS holds functionally segregated subdivisions for different categories of facial movements. We used high-resolution functional magnetic resonance imaging (fMRI) at 7T in 16 volunteers to compare STS activation to faces displaying angry or happy expressions, eye-gaze shifts, and lip-speech movements. Combining univariate and multivariate analyses, we show a systematic topological organization within STS, with gaze-related activity predominating in the most posterior and superior sector, speech-related activity in the anterior sector, and emotional expressions represented in the intermediate middle STS...
November 11, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/29137053/prognostic-value-of-high-resolution-magnetic-resonance-imaging-in-evaluating-carotid-atherosclerotic-plaque-in-patients-with-ischemic-stroke
#17
Jin-Er Shu, Ming-Liang Ying, Xiao-Rong Chen, Jian-Jun Hua, Jie-Ting Fu, Xiu-Mei Xia, Yong-Hao Pan, Yang Jiang
BACKGROUND: Ischemic stroke (IS) is a devastating occurrence affecting millions worldwide. This study aimed to evaluate the prognostic value of high-resolution magnetic resonance imaging (HRMRI) in assessing carotid atherosclerotic plaque in IS patients. METHODS: Between January 2013 and March 2015, 338 IS patients were recruited for the investigative purposes of the study. All participants of the study underwent an HRMRI inspection procedure after being admitted into the hospital...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29135874/meni%C3%A3-re-and-friends-imaging-and-classification-of-hydropic-ear-disease
#18
Robert Gürkov
BACKGROUND: Over 75 years ago, endolymphatic hydrops was discovered as the pathologic correlate of Menière's disease. However, this pathologic finding could be ascertained only in postmortem histologic studies. Due to this diagnostic dilemma and the variable manifestation of the various audiovestibular symptoms, diagnostic classification systems based on clinical findings have been used hitherto. METHODS: A review of the literature of magnetic resonance (MR) imaging of hydropic ear disease...
December 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29135869/usefulness-of-high-resolution-3d-multi-sequences-for-peripheral-facial-palsy-differentiation-between-bell-s-palsy-and-ramsay-hunt-syndrome
#19
Junko Kuya, Keita Kuya, Yuki Shinohara, Yasuomi Kunimoto, Hiroaki Yazama, Toshihide Ogawa, Hiromi Takeuchi
OBJECTIVE: To investigate the usefulness of magnetic resonance imaging (MRI) including three-dimensional (3D) sequences in the differentiation between Bell's palsy (BP) and Ramsay Hunt syndrome (RHS). STUDY DESIGN: A prospective study. SETTING: Tertiary care center. PATIENTS: Twenty patients: 15 patients with BP and five patients with RHS. INTERVENTION: Diagnostic. MAIN OUTCOME MEASURE: Clinical diagnosis (BP or RHS)...
December 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29131770/differentiation-of-solid-renal-tumors-with-multiparametric-mr-imaging
#20
Camila Lopes Vendrami, Carolina Parada Villavicencio, Todd J DeJulio, Argha Chatterjee, David D Casalino, Jeanne M Horowitz, Daniel T Oberlin, Guang-Yu Yang, Paul Nikolaidis, Frank H Miller
Characterization of renal tumors is critical to determine the best therapeutic approach and improve overall patient survival. Because of increased use of high-resolution cross-sectional imaging in clinical practice, renal masses are being discovered with increased frequency. As a result, accurate imaging characterization of these lesions is more important than ever. However, because of the wide array of imaging features encountered as well as overlapping characteristics, identifying reliable imaging criteria for differentiating malignant from benign renal masses remains a challenge...
November 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
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