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high resolution magnetic resonance imaging

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https://www.readbyqxmd.com/read/29788872/recent-advances-in-magnetic-nanoparticle-based-molecular-probes-for-hepatocellular-carcinoma-diagnosis-and-therapy
#1
Qi Zhang, Sudan Wang, Ruirui Qiao, Michael Whittaker, John Quinn, Thomas P Davis, Hongjun Li
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, leading to the second most likely cause of cancer-related deaths. Medical imaging is crucial in clinic for HCC screening and diagnosis. Due to the relatively high special resolution and excellent sensitivity, magnetic resonance imaging (MRI) by using magnetic nanoparticle-based contrast agents has been used so far in HCC imaging and staging, demonstrating great potential and promising in vivo applications. This review focuses on the use of different magnetic nanoparticles for construction of HCC nanoprobes for MR imaging and theranostic purpose...
May 15, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29788854/-myocardial-clefts-incidental-findings-in-parainfectious-myocarditis
#2
Florian Berger, Christopher Hansi, Tilo Niemann
Myocardial Clefts - Incidental Findings in Parainfectious Myocarditis Abstract. We report a 23-year-old woman with parainfectious myocarditis due to gastroenteritis. A transthoracic echocardio-graphy revealed a recess in the left inferobasal ventricle. For further investigation, cardiac magnetic resonance imaging was initiated, which revealed a myocardial cleft, a harmless structural variation of the heart. Cardiac magnetic resonance is a non-invasive imaging technique with a high spatial and temporal resolution that enables a precise depiction of the cardiac anatomy and therefore allows for a differentiation between normal and pathological structural variations of the heart...
2018: Praxis
https://www.readbyqxmd.com/read/29787383/deep-learning-for-undersampled-mri-reconstruction
#3
Chang Min Hyun, Hwa Pyung Kim, Sung Min Lee, Sungchul Lee, Jin Keun Seo
This paper presents a deep learning method for faster magnetic resonance imaging (MRI) by reducing k-space data with sub-Nyquist sampling strategies and provides a rationale for why the proposed approach works well. Uniform subsampling is used in the time-consuming phase-encoding direction to capture high-resolution image information, while permitting the image-folding problem dictated by the Poisson summation formula. To deal with the localization uncertainty due to image folding, a small number of low-frequency k-space data are added...
May 22, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29787354/optical-coherence-tomography-of-the-tympanic-membrane-and-middle-ear-a-review
#4
Hsern Ern Ivan Tan, Peter Luke Santa Maria, Philip Wijesinghe, Brendan Francis Kennedy, Benjamin James Allardyce, Robert Henry Eikelboom, Marcus David Atlas, Rodney James Dilley
Objective To evaluate the recent developments in optical coherence tomography (OCT) for tympanic membrane (TM) and middle ear (ME) imaging and to identify what further development is required for the technology to be integrated into common clinical use. Data Sources PubMed, Embase, Google Scholar, Scopus, and Web of Science. Review Methods A comprehensive literature search was performed for English language articles published from January 1966 to January 2018 with the keywords "tympanic membrane or middle ear,"optical coherence tomography," and "imaging...
May 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29784633/confocal-laser-endomicroscopy-and-optical-coherence-tomography-for-the-diagnosis-of-prostate-cancer-a-needle-based-in-vivo-feasibility-study-protocol-ideal-phase-2a
#5
Abel Swaan, Christophe K Mannaerts, Matthijs Jv Scheltema, Jakko A Nieuwenhuijzen, C Dilara Savci-Heijink, Jean Jmch de la Rosette, R Jeroen A van Moorselaar, Ton G van Leeuwen, Theo M de Reijke, Daniel Martijn de Bruin
BACKGROUND: Focal therapy for prostate cancer has been proposed as an alternative treatment to whole-gland therapies in selected men to diminish side effects in localized prostate cancer. As nowadays imaging cannot offer complete prostate cancer disease characterization, multicore systematic biopsies are recommended (transrectal or transperineal). Optical imaging techniques such as confocal laser endomicroscopy and optical coherence tomography allow in vivo, high-resolution imaging. Moreover, they can provide real-time visualization and analysis of tissue and have the potential to offer additive diagnostic information...
May 21, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29784058/fat-suppressed-gadolinium-enhanced-isotropic-high-resolution-3d-gre-t1wi-for-predicting-small-node-metastases-in-patients-with-rectal-cancer
#6
Yan Chen, Xinyue Yang, Ziqiang Wen, Baolan Lu, Xiaojuan Xiao, Bingqi Shen, Shenping Yu
BACKGROUND: To investigate the application value of fat-suppressed gadolinium-enhanced isotropic high-resolution 3D-GRE-T1WI in regional nodes with different short-axis diameter ranges in rectal cancer, especially in nodes ≤5 mm. METHODS: Patients with rectal adenocarcinoma confirmed by postoperative histopathology were included, and all the patients underwent preoperative 3.0 T rectal magnetic resonance imaging (MRI) and total mesorectal excision (TME) within 2 weeks after an MR scan...
May 21, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29780922/mri-findings-of-contralateral-oculomotor-nerve-palsy-in-parry-romberg-syndrome
#7
Emily K Tam, Marcela Lonngi, Joseph L Demer
Purpose: To study a case of right Parry Romberg syndrome associated with contralateral oculomotor nerve palsy using high-resolution cerebral and orbital magnetic resonance imaging (MRI). Observations: There were no brain MRI abnormalities. However, there was marked enophthalmos on the right with reduction of orbital fat. Extraocular muscles contracted normally in the right eye, but in the left eye, there was reduced contractility of the medial, inferior, and superior rectus muscles...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29773892/metabolite-cycled-density-weighted-concentric-rings-k-space-trajectory-dw-crt-enables-high-resolution-1-h-magnetic-resonance-spectroscopic-imaging-at-3-tesla
#8
Adam Steel, Mark Chiew, Peter Jezzard, Natalie L Voets, Puneet Plaha, Michael Albert Thomas, Charlotte J Stagg, Uzay E Emir
Magnetic resonance spectroscopic imaging (MRSI) is a promising technique in both experimental and clinical settings. However, to date, MRSI has been hampered by prohibitively long acquisition times and artifacts caused by subject motion and hardware-related frequency drift. In the present study, we demonstrate that density weighted concentric ring trajectory (DW-CRT) k-space sampling in combination with semi-LASER excitation and metabolite-cycling enables high-resolution MRSI data to be rapidly acquired at 3 Tesla...
May 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29772956/lumbar-muscle-structure-predicts-operational-postures-in-active-duty-marines
#9
David B Berry, Bahar Shahidi, Ana E Rodríguez-Soto, Jan M Hughes-Austin, Karen R Kelly, Samuel R Ward
Study Design Cross-sectional. Background The relationship between lumbar spine posture and muscle structure is not well understood. Objectives Investigate the predictive capacity of muscle structure on lumbar spine posture in active duty Marines. Methods Fouty-three Marines were scanned using an upright magnetic resonance imaging (MRI) scanner while standing unloaded and standing, sitting, and prone on elbows with body armor. Cobb, horizontal, and sacral angles were measured. Marines were then scanned unloaded in supine using a supine MRI scanner...
May 17, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29770490/functional-magnetic-resonance-electrical-impedance-tomography-fmreit-sensitivity-analysis-using-an-active-bidomain-finite-element-model-of-neural-tissue
#10
Rosalind J Sadleir, Fanrui Fu, Munish Chauhan
PURPOSE: A direct method of imaging neural activity was simulated to determine typical signal sizes. METHODS: An active bidomain finite-element model was used to estimate approximate perturbations in MR phase data as a result of neural tissue activity, and when an external MR electrical impedance tomography imaging current was added to the region containing neural current sources. RESULTS: Modeling-predicted, activity-related conductivity changes should produce measurable differential phase signals in practical MR electrical impedance tomography experiments conducted at moderate resolution at noise levels typical of high field systems...
May 16, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29769642/high-resolution-imaging-of-myeloperoxidase-activity-sensors-in-human-cerebrovascular-disease
#11
Youssef Z Wadghiri, Dung Minh Hoang, Anita Leporati, Matthew J Gounis, Aurora Rodríguez-Rodríguez, Mary L Mazzanti, John P Weaver, Ajay K Wakhloo, Peter Caravan, Alexei A Bogdanov
Progress in clinical development of magnetic resonance imaging (MRI) substrate-sensors of enzymatic activity has been slow partly due to the lack of human efficacy data. We report here a strategy that may serve as a shortcut from bench to bedside. We tested ultra high-resolution 7T MRI (µMRI) of human surgical histology sections in a 3-year IRB approved, HIPAA compliant study of surgically clipped brain aneurysms. µMRI was used for assessing the efficacy of MRI substrate-sensors that detect myeloperoxidase activity in inflammation...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29764720/altered-somatosensory-processing-in-parkinson-s-disease-and-modulation-by-dopaminergic-medications
#12
Aimee J Nelson, Tasnuva Hoque, Carolyn Gunraj, Robert Chen
BACKGROUND: Somatosensory abnormalities contribute to the pathophysiology of Parkinson's disease (PD). The goal of this study was to identify abnormalities in the tactile-evoked activation of the somatosensory and motor cortices in PD, and in a sensorimotor circuit that traverses both of these cortical loci. The second goal was to investigate the impact of dopaminergic medication on these measures. METHODS: Individuals with PD (n = 10, age 61 ± 8 years) and aged-matched controls (n = 11, age 52...
May 7, 2018: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29762436/preoperative-analysis-of-venous-anatomy-before-deep-inferior-epigastric-perforator-free-flap-breast-reconstruction-using-ferumoxytol-enhanced-magnetic-resonance-angiography
#13
John Dortch, Antonio J Forte, Candice Bolan, Pujan Kandel, Galen Perdikis
BACKGROUND: Venous congestion after deep inferior epigastric artery perforator (DIEP) flap breast reconstruction is a complication that may be partially attributable to variations in venous abdominal wall anatomy. In previous work, we have shown that ferumoxytol may be used as a bloodpool contrast agent to perform high-resolution venous imaging. Our current aim was to use this technology to perform a detailed analysis of the venous anatomy among patients undergoing DIEP flap breast reconstruction...
May 14, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29760665/left-ventricular-trabeculations-decrease-the-wall-shear-stress-and-increase-the-intra-ventricular-pressure-drop-in-cfd-simulations
#14
Federica Sacco, Bruno Paun, Oriol Lehmkuhl, Tinen L Iles, Paul A Iaizzo, Guillaume Houzeaux, Mariano Vázquez, Constantine Butakoff, Jazmin Aguado-Sierra
The aim of the present study is to characterize the hemodynamics of left ventricular (LV) geometries to examine the impact of trabeculae and papillary muscles (PMs) on blood flow using high performance computing (HPC). Five pairs of detailed and smoothed LV endocardium models were reconstructed from high-resolution magnetic resonance images (MRI) of ex-vivo human hearts. The detailed model of one LV pair is characterized only by the PMs and few big trabeculae, to represent state of art level of endocardial detail...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29760276/early-blood-brain-barrier-disruption-in-ischemic-stroke-initiates-multifocally-around-capillaries-venules
#15
Angelika Hoffmann, Tassilo Dege, Reiner Kunze, Anne-Sophie Ernst, Holger Lorenz, Laura-Inés Böhler, Thomas Korff, Hugo H Marti, Sabine Heiland, Martin Bendszus, Xavier Helluy, Mirko Pham
BACKGROUND AND PURPOSE: Detection and localization of the early phase of blood-brain barrier disruption (BBBD) in vivo during cerebral ischemia/reperfusion injury remain a major challenge but may be a relevant outcome parameter in stroke. METHODS: We studied early BBBD in mice after transient middle cerebral artery occlusion by multimodal, high-field (9.4T) in vivo magnetic resonance imaging, including the contrast agent gadofluorineM as an albumin-binding tracer...
May 14, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29755611/morphological-biomarker-differentiating-mci-converters-from-nonconverters-longitudinal-evidence-based-on-hemispheric-asymmetry
#16
Xiaojing Long, Chunxiang Jiang, Lijuan Zhang
Identifying subjects with mild cognitive impairment (MCI) who may probably progress to Alzheimer's disease (AD) is important for better understanding the disease mechanisms and facilitating early treatments. In addition to the direct volumetric and thickness measurement based on high-resolution magnetic resonance imaging (MRI), hemispheric asymmetry could be a potential index to detect morphological variations in MCI patients with a high risk of conversion to AD. The present study collected a set of longitudinal MRI data from 53 MCI converters and nonconverters and investigated the asymmetry differences between groups...
2018: Behavioural Neurology
https://www.readbyqxmd.com/read/29754519/the-role-of-imaging-in-early-diagnosis-and-prevention-of-joint-damage-in-inflammatory-arthritis
#17
Jiang Yue, Dongze Wu, Lai-Shan Tam
Inflammatory arthritis is characterized by chronic inflammation in the synovium, associated with degradation of cartilage and erosion of juxta-articular bone. The bone loss and joint destruction mediated by aberrant immunological responses resulting in proinflammatory cytokine release and various immune cell activation are known as osteoimmunology. Areas covered: A structured literature search including Medline and PubMed, Cochrane meta-analyses and abstracts of international congresses was performed to review joint damage in inflammatory arthritis in terms of pathogenesis, novel imaging assessment and prevention...
May 13, 2018: Expert Review of Clinical Immunology
https://www.readbyqxmd.com/read/29754069/high-resolution-vessel-wall-mri-and-vasculopathy-related-to-herpes-zoster-ophthalmicus
#18
Jae W Song, Sam Ojeda, Javier M Romero
Varicella zoster virus is a common viral infection with over 50% of patients over the age of 80 years infected with the virus. Following reactivation, some patients succumb to complications of VZV reactivation with neurologic and optic pathway pathology such as VZV vasculopathy resulting in transient ischemic attacks, strokes, aneurysms, as well as optic neuritis. We show that high resolution vessel wall magnetic resonance imaging can aid in the diagnosis of this condition with circumferential wall thickening and enhancement of the infected vessels...
May 3, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/29753942/magnetic-resonance-imaging-technology-bridging-the-gap-between-noninvasive-human-imaging-and-optical-microscopy
#19
REVIEW
Jonathan R Polimeni, Lawrence L Wald
Technological advances in Magnetic Resonance Imaging (MRI) have provided substantial gains in the sensitivity and specificity of functional neuroimaging. Mounting evidence demonstrates that the hemodynamic changes utilized in functional MRI can be far more spatially and thus neuronally specific than previously believed. This has motivated a push toward novel, high-resolution MR imaging strategies that can match this biological resolution limit while recording from the entire human brain. Although sensitivity increases are a necessary component, new MR encoding technologies are required to convert improved sensitivity into higher resolution...
May 10, 2018: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/29753843/using-temporal-ica-to-selectively-remove-global-noise-while-preserving-global-signal-in-functional-mri-data
#20
Matthew F Glasser, Timothy S Coalson, Janine D Bijsterbosch, Samuel J Harrison, Michael P Harms, Alan Anticevic, David C Van Essen, Stephen M Smith
Temporal fluctuations in functional Magnetic Resonance Imaging (fMRI) have been profitably used to study brain activity and connectivity for over two decades. Unfortunately, fMRI data also contain structured temporal "noise" from a variety of sources, including subject motion, subject physiology, and the MRI equipment. Recently, methods have been developed to automatically and selectively remove spatially specific structured noise from fMRI data using spatial Independent Components Analysis (ICA) and machine learning classifiers...
May 10, 2018: NeuroImage
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