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radiation arteritis

Haner Direskeneli
Takayasu's arteritis (TAK) is a rare, chronic, large-vessel vasculitis (LVV) that predominantly affects aorta, its major branches and the pulmonary arteries. Recent controversial issues in the diagnosis, disease assessment and prognosis in TAK are discussed in this review. In recent years, conventional angiography, the standard method for the initial diagnosis, seems to have been replaced by the new imaging modalities, such as MRI and 18F-FDG-PET. Less invasive techniques (CT/MRI) are now suggested first, compared to conventional angiography, and MRI is preferable to CT with less contrast load/radiation...
March 2017: Clinical and Experimental Rheumatology
Michael Czihal, Christian Lottspeich, Ulrich Hoffmann
Nowadays noninvasive vascular imaging has an important role in the diagnostic work-up of the large vessel vasculitides (LVV), most importantly giant cell arteritis (GCA) and Takayasu arteritis. Among the imaging modalities available, ultrasound (US) has several important advantages, including low costs, rapid and repetitive availability without exposure to radiation, and high spatial resolution for assessment of large and medium-sized arteries. Therefore, US can be regarded the first line imaging method in suspected LVV...
March 23, 2017: VASA. Zeitschrift Für Gefässkrankheiten
Vasken Dilsizian, Hossein Jadvar
It has been reported that fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography (PET) may detect the inflammatory state and macrophage burden of atherosclerotic plaques and potentially identify vulnerable plaques. However, published reports have been inconsistent in this area. Tavakoli et al ( 1 ) hypothesized that differential regulation of macrophage glucose metabolism by macrophage colony-stimulating factor (M-CSF; inflammation resolving) and granulocyte-M-CSF (GM-CSF; proinflammatory) may contribute to the inconsistency of FDG vessel wall inflammation...
April 2017: Radiology
Hao D Pham, Melissa G Prather, Daniel S Rush
Radiation arteritis is a rare cause of lower extremity peripheral arterial occlusive disease, and has been traditionally treated with open interventions. There have been only a few reported cases of endovascular interventions for this disease. Previous reports described endovascular treatment in the iliac and common femoral regions, but intervention in the superficial femoral artery have not been described. Described here is a case of acute lower extremity ischemia caused by remote radiation arteritis of the superficial femoral artery, which was successfully treated by percutaneous endovascular technique...
November 1, 2016: American Surgeon
Sophie Mavrogeni, George Markousis-Mavrogenis, Genovefa Kolovou
Immunoglobulin 4-related disease (IgG4-related disease) is a systemic inflammatory disease that presents with increases of serum IgG4. It may affect various systems, including the cardiovascular (CV) system. Assessment of serum IgG4 levels and involved organ biopsy are necessary for diagnosis. IgG4-related disease is characterized by fibrosclerosis, lymphocytic infiltration and presence of IgG4-positive plasma cells. The disease usually responds to treatment with corticosteroids and/or immunosuppressive medication...
January 2017: European Journal of Radiology
Ashish J Mathew, Ruchika Goel, Sathish Kumar, Debashish Danda
Childhood-onset Takayasu arteritis (c-TA) is a distinct subset affecting a wide age group, ranging from young infants to adolescents and it differs from adult TA in many aspects. There is scarcity of data on c-TA worldwide. The disease is classified using the European League Against Rheumatism/Pediatric Rheumatology International Trials Organization/Pediatric Rheumatology European Society criteria. The non-specific nature of presenting complaints and lack of appropriate biomarkers delay the early diagnosis of this illness and many children present with complications, which become irreversible once they set in...
February 2016: International Journal of Rheumatic Diseases
Simon Wing, Lisa G Rider, Jay R Johnson, Federick W Miller, Eric L Matteson, Cynthia S Crowson, Sherine E Gabriel
OBJECTIVE: To examine the influence of solar cycle and geomagnetic effects on the incidence of giant cell arteritis (GCA) and rheumatoid arthritis (RA). METHODS: We used data from patients with GCA (1950-2004) and RA (1955-2007) obtained from population-based cohorts. Yearly trends in age-adjusted and sex-adjusted incidence were correlated with the F10.7 index (solar radiation at 10.7 cm wavelength, a proxy for the solar extreme ultraviolet radiation) and AL index (a proxy for the westward auroral electrojet and a measure of geomagnetic activity)...
2015: BMJ Open
Christopher J Busken, Bradley R Grimsley, William P Shutze
Radiation-associated venous stenosis is not as well described in the literature as radiation-induced arteritis and is mainly limited to case reports. Treatment of radiation-associated venous stenosis may be challenged by the patient's comorbidities, such as cancer, compressive tumor, or secondary thrombophilia. The endovascular treatment of venous occlusions is now widespread and is usually the preferred modality. This is especially true for lesions of the iliac venous system. However, the development of arterial stenosis after iliac vein stenting has not previously been reported in the literature as a complication...
2015: Annals of Vascular Surgery
Yasuhiro Katayama, Satoko Yamawaki, Michio Yoshimura, Rino Aya, Tatsuki Enoshiri, Katsuhiro Yoshikawa, Motoko Naitoh, Shigehiko Suzuki
Although combination therapy for keloid including postoperative radiation therapy (RT) is common, the radiation toxicity of RT in a patient with a history of collagen vascular disease has not been fully recognized. We experienced a case of an acute radiodermatitis in a patient with keloid. This patient had a chest keloid because of the bypass surgery for Takayasu's arteritis. After we performed an excision and postoperative RT, severe radiodermatitis occurred. We speculate that the higher single dose and the use of electron beams may be related to the onset of severe acute radiodermatitis in this case...
December 2014: Plastic and Reconstructive Surgery. Global Open
Khalid Bashar, Donagh Healy, Mary Clarke-Moloney, Paul Burke, Eamon Kavanagh, Stewart-Redmond Walsh
INTRODUCTION: Radiation arteritis following neck irradiation as a treatment for head and neck malignancy has been well documented. The long-term sequelae of radiation exposure of the carotid arteries may take years to manifest clinically, and extra-cranial carotid artery (ECCA) stenosis is a well-recognised vascular complication. These carotid lesions should not be regarded as benign and should be treated in the same manner as standard carotid stenosis. Previous studies have noted increased cerebrovascular events such as stroke in this cohort of patients because of high-grade symptomatic carotid stenosis resulting in emboli...
2014: PloS One
P Sewerin, B Ostendorf
Modern imaging procedures play an import role in diagnostic and therapy-control in rheumatic diseases. Reasons are the continuous development, the evaluation and the implementation in local / international guidelines and classification criteria. According to new therapeutic goals and the aim of clinical and radiological remission the early diagnosis and sufficient therapy-control is unalterable. The ultrasound is today an inherent tool in the early diagnosis of joint- and vascular diseases and is used comprehensively in rheumatic diseases...
September 2014: Deutsche Medizinische Wochenschrift
Ahmed Abdel Khalek Abdel Razek, Hortensia Alvarez, Stephen Bagg, Sherif Refaat, Mauricio Castillo
Cerebral vasculitis is characterized by inflammation of the walls of blood vessels and may affect vessels of any size. The pathogenesis of vasculitis remains poorly understood. Vasculitis may affect large vessels (Takayasu arteritis, giant cell arteritis), medium-sized vessels (Kawasaki disease, polyarteritis nodosa), small vessels (immunoglobulin A vasculitis, microscopic polyangiitis, granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiitis), or variable-sized vessels (Behçet disease, Cogan syndrome)...
July 2014: Radiographics: a Review Publication of the Radiological Society of North America, Inc
Khalid Bashar, Seamus McHugh, Paul Burke, Eamon Kavanagh
Radiation arteritis can lead to significant extracranial carotid artery stenosis, affecting the circle of Willis. Cerebral hypoperfusion due to arterial insufficiency is often considered as a differential diagnosis in cases of syncope but rarely proven. We present a case of a 61-year-old man with repeated episodes of syncope-negative cardiac investigations. He had a history of cervical radiation therapy for tonsillar squamous cell carcinoma 15 years previously. Carotid duplex revealed bilateral carotid occlusive disease...
2014: BMJ Case Reports
Chao-Bao Luo, Wan-Yuo Guo, Feng-Chi Chang, Hsiu-Mei Wu, Michael M H Teng, Chung-Jung Lin, David H C Pan, Wen-Yuh Chung, Cheng-Yen Chang
BACKGROUND: The angioarchitecture of arteriovenous fistulas (AVFs) of cerebral arteriovenous malformation (CAVM) after stereotactic radiosurgery (SRS) remain unclear. The purpose of this study is to report the angiographic change of AVF components of CAVMs after SRS and outcomes of endovascular embolisation. METHODS: From 2002 to 2012, a total of 523 CAVMs had been treated primarily by SRS with more than 3-year latency. Among these databases, there were 19 patients with 21 AVFs undergoing embolization after SRS...
January 2014: Acta Neurochirurgica
Yu-Chen Wang, Te-Chun Hsieh, Shang-Wen Chen, Kuo-Yang Yen, Chia-Hung Kao, Kuan-Cheng Chang
No abstract text is available yet for this article.
April 2013: JACC. Cardiovascular Imaging
Richard K Cheng, Michael S Lee, Atsuko Seki, Richard J Shemin, Daniel Cruz, Gentian Lluri, George D Mitchell, Eric H Yang
BACKGROUND: Hodgkin's lymphoma (HL) comprises of 4% of malignancies diagnosed in children from birth to 14 years of age. While overall survival rates have increased, HL survivors can be at risk of late cardiovascular complications from radiotherapy. HL survivors with a history of mediastinal RT have been found to have an increased incidence of myocardial infarction, angina, congestive heart failure, and valvular disorders compared to the general population. METHODS: A 33 year old female with a history of HL status post chemotherapy and mediastinal radiation 11 years ago became symptomatic with multivessel coronary artery disease with aggressive progression of her disease despite coronary bypass graft surgery, patch angioplasty of the left main coronary artery (LMCA) with an extracellular bioscaffold, and repeated percutaneous coronary intervention of the LMCA...
July 2013: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
A Azak, B Huddam, G Koçak, F Kiliç, E Koçak, M Duranay
Takayasu arteritis is a chronic inflammatory disease that primarily affects large arteries such as the aorta and its proximal branches. The association between Takayasu arteritis and ulcerative colitis is an extremely rare condition. Ulcerative colitis is an inflammatory bowel disease, clinical presentation is not specific and may mimic Crohn's disease, radiation colitis, ischemic colitis, a variety of infectious processes, and colitis related to medications. Herein we report a case of Takayasu arteritis who had been misdiagnosed and treated as ulcera-...
March 2012: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
Sophie Mavrogeni, Theodoros Dimitroulas, Sofia N Chatziioannou, George Kitas
OBJECTIVES: Takayasu arteritis is a rare large vessel vasculitis of unknown etiology, in which both early diagnosis and follow-up present very significant challenges. The high incidence of disease-associated morbidity and significant risk of premature death-particularly in young adults-mandate the need to facilitate early diagnosis and aggressive treatment where appropriate. The aim of this review is to summarize the current level of knowledge regarding the usefulness of evolving imaging modalities in the diagnostic workup and management of patients suffering with Takayasu arteritis...
February 2013: Seminars in Arthritis and Rheumatism
Ilya Shoimer, Judy Wismer
BACKGROUND: Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous disorder characterized by giant cells in the dermis phagocytosing damaged elastin fragments. OBJECTIVE: We report a case of a 71-year-old man presenting with erythematous plaques in predominantly sun-exposed areas. METHOD: A diagnosis of AEGCG was made based on the clinical and histologic picture, and treatment with systemic steroids was initiated. However, while tapering the steroid dose, the patient developed a radiating headache that progressed to temporal arteritis and eventual blindness in the right eye...
September 2011: Journal of Cutaneous Medicine and Surgery
Lee J Goldstein, Joseph D Ayers, Scott Hollenbeck, Jason A Spector, Ageliki G Vouyouka
Despite several reports of proximal arm ischemia due to radiation therapy, there are no reports of hand ischemia, presumably due to the rarity of radiation treatment of the distal upper extremity. We present a case of a 42-year-old male presenting with acute hand ischemia 36 years after being treated with forearm radiation for Ewing's sarcoma. Angiography demonstrated a patent brachial artery, occluded radial and ulnar arteries in the forearm, and a normal-caliber reconstituted radial artery at the anatomical snuffbox feeding a patent palmar arch...
February 2010: Annals of Vascular Surgery
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