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https://www.readbyqxmd.com/read/27911036/properties-of-embryoid-bodies
#1
REVIEW
Joshua M Brickman, Palle Serup
Embryoid bodies (EBs) have been popular in vitro differentiation models for pluripotent stem cells for more than five decades. Initially, defined as aggregates formed by embryonal carcinoma cells, EBs gained more prominence after the derivation of karyotypically normal embryonic stem cells from early mouse blastocysts. In many cases, formation of EBs constitutes an important initial step in directed differentiation protocols aimed at generated specific cell types from undifferentiated stem cells. Indeed state-of-the-art protocols for directed differentiation of cardiomyocytes still rely on this initial EB step...
December 2, 2016: Wiley Interdisciplinary Reviews. Developmental Biology
https://www.readbyqxmd.com/read/27909162/mental-health-stigma-impact-on-mental-health-treatment-attitudes-and-physical-health
#2
Amy E Sickel, Jason D Seacat, Nina A Nabors
The purpose of this study was to test two models of the impact of mental health stigma on both attitudes toward seeking psychological help and physical health. General self-efficacy, self-esteem, and anxiety were tested as potential mediators of these two relationships. A sample of adults (N = 423) aged 18-72 years was surveyed using the participant pool of a large, distance learning university. Structural equation modeling results indicated that mental health stigma directly and indirectly influenced treatment attitudes and physical health...
December 1, 2016: Journal of Health Psychology
https://www.readbyqxmd.com/read/27898387/a-novel-adaboost-framework-with-robust-threshold-and-structural-optimization
#3
Peng-Bo Zhang, Zhi-Xin Yang
The AdaBoost algorithm is a popular ensemble method that combines several weak learners to boost generalization performance. However, conventional AdaBoost.RT algorithms suffer from the limitation that the threshold value must be manually specified rather than chosen through a self-adaptive mechanism, which cannot guarantee a result in an optimal model for general cases. In this paper, we present a generic AdaBoost framework with robust threshold mechanism and structural optimization on regression problems...
November 24, 2016: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/27894229/-self-reported-experience-in-patients-treated-with-hepatitis-c-direct-acting-antivirals
#4
Irene Cañamares Orbis, Javier Saez de la Fuente, Ismael Escobar Rodriguez, Concepción Esteban Alba, Ana Such Díaz, Ismael Escobar Rodríguez
BACKGROUND AND OBJECTIVE: To learn about and analyze the self-reported treatment experience of HCV patients who started treatment with direct acting antivirals agents (DAA), at a real-time, proactive and integrated into the pharmaceutical care healthcare process, using a prospective questionnaire completed by patients as clinical tool. MATERIAL AND METHODS: Observational and cross-sectional study conducted between April (start of the National Strategic Plan) and December 2015 in the Outpatient Pharmacy Service...
November 1, 2016: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/27892659/university-students-with-dyslexia-a-qualitative-exploratory-study-of-learning-practices-challenges-and-strategies
#5
Lois MacCullagh, Agnes Bosanquet, Nicholas A Badcock
People with dyslexia are vastly under-represented in universities (Katusic et al., , Richardson & Wydell, ; Stampoltzis & Polychronopoulou, ). This situation is of concern for modern societies that value social justice. This study was designed to explore learning experiences of university students with dyslexia and factors that could contribute to their success. Thirteen students with dyslexia and 20 non-dyslexic peers were interviewed about their university learning experiences using a semi-structured qualitative approach...
November 28, 2016: Dyslexia: the Journal of the British Dyslexia Association
https://www.readbyqxmd.com/read/27891356/attitudes-and-perceptions-of-medical-undergraduates-towards-mobile-learning-m-learning
#6
Rakesh Narayan Patil, Balaji D Almale, Mrunal Patil, Amit Gujrathi, Supriya Dhakne-Palwe, Anuradha R Patil, Shriram Gosavi
INTRODUCTION: Mobile technology is one of the latest extensions of technological innovations that can be integrated into medical education. With the aid of these devices, students learn faster outside the classroom by having quick access to the internet and easy retrieval of required health related learning resources to keep alongside of recent trend and development. In medicine practice one has to continuously update his/her medical knowledge and mobile learning will serve as a tool for self-directed learning...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27882520/app-use-in-psychiatric-education-a-medical-student-survey
#7
Cecilia Lau, Venkata Kolli
OBJECTIVE: The objective of the study is to understand and appraise app use by medical students during their clerkships. METHODS: Following Creighton University IRB approval, a voluntary and anonymous paper-based, 15-question survey was distributed to third-year medical students. Data were analyzed using Microsoft Excel. RESULTS: Of 112 medical students available, 76.7% (86) participated in the survey. All participants owned a smartphone or tablet with 84...
November 23, 2016: Academic Psychiatry
https://www.readbyqxmd.com/read/27877117/general-habit-propensity-relates-to-the-sensation-seeking-subdomain-of-impulsivity-but-not-obesity
#8
Anja Dietrich, Sanne de Wit, Annette Horstmann
According to dual-system theory, instrumental learning and performance depend on the balance between goal-directed and habitual action control. Overreliance on habits has been argued to characterize clinical conditions such as drug addiction or obsessive-compulsive disorder as well as obesity and excessive impulsivity. A tendency toward habitual action control in obesity has already been indicated in the food domain. However, impairments might not be restricted to eating behavior. This has been suggested by domain-general obesity-associated disturbances in executive function as well as alterations in corticostriatal circuits underlying the goal-directed and habitual systems...
2016: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/27875379/the-decision-neuroscience-perspective-on-suicidal-behavior-evidence-and-hypotheses
#9
Alexandre Y Dombrovski, Michael N Hallquist
PURPOSE OF REVIEW: Suicide attempts are usually regretted by people who survive them. Furthermore, addiction and gambling are over-represented among people who attempt or die by suicide, raising the question whether their decision-making is impaired. Advances in decision neuroscience have enabled us to investigate decision processes in suicidal people and to elucidate putative neural substrates of disadvantageous decision-making. RECENT FINDINGS: Early studies have linked attempted suicide to poor performance on gambling tasks...
January 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/27875237/automatic-facial-expression-recognition-system-using-deep-network-based-data-fusion
#10
Anima Majumder, Laxmidhar Behera, Venkatesh K Subramanian
This paper presents a novel automatic facial expressions recognition system (AFERS) using the deep network framework. The proposed AFERS consists of four steps: 1) geometric features extraction; 2) regional local binary pattern (LBP) features extraction; 3) fusion of both the features using autoencoders; and 4) classification using Kohonen self-organizing map (SOM)-based classifier. This paper makes three distinct contributions. The proposed deep network consisting of autoencoders and the SOM-based classifier is computationally more efficient and performance wise more accurate...
November 17, 2016: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/27853349/developing-crossmodal-expression-recognition-based-on-a-deep-neural-model
#11
Pablo Barros, Stefan Wermter
A robot capable of understanding emotion expressions can increase its own capability of solving problems by using emotion expressions as part of its own decision-making, in a similar way to humans. Evidence shows that the perception of human interaction starts with an innate perception mechanism, where the interaction between different entities is perceived and categorized into two very clear directions: positive or negative. While the person is developing during childhood, the perception evolves and is shaped based on the observation of human interaction, creating the capability to learn different categories of expressions...
October 2016: Adaptive Behavior
https://www.readbyqxmd.com/read/27848199/anesthesiology-resident-wellness-program-at-the-university-of-saskatchewan-concept-and-development
#12
Anita Chakravarti, Mateen Raazi, Jennifer O'Brien, Breanna Balaton
PURPOSE: We describe the need for an anesthesiology resident wellness program (ARWP) and the challenges associated with its development and implementation. We also present the results of a preliminary program evaluation. METHODS: We conducted a needs assessment of Canadian anesthesiology residency programs for a formal ARWP. This endeavor involved both a cross-sectional survey and a focus group of Canadian anesthesiology residency training program directors (PDs)...
November 15, 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/27844198/anesthesiology-resident-wellness-program-at-the-university-of-saskatchewan-curriculum-content-and-delivery
#13
Anita Chakravarti, Mateen Raazi, Jennifer O'Brien, Breanna Balaton
Resident and physician health are increasingly recognized by the Royal College of Physicians and Surgeons of Canada and its CanMEDS framework as integral to residency training in Canada. Resident stress, burnout, and depression also have implications for patient care. Although curricula have been advocated to promote resident wellness and resilience, no such published curricula exist to guide programs in addressing these needs. The purpose of this article is to describe the curriculum content and delivery of the Anesthesiology Residency Wellness Program (ARWP) at the University of Saskatchewan...
November 14, 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/27836424/executive-function-in-children-born-preterm-risk-factors-and-implications-for-outcome
#14
REVIEW
H Gerry Taylor, Caron A C Clark
Executive function (EF) refers to the set of cognitive processes involved in the self-regulation of emotion and goal-directed behavior. These skills and the brain systems that support them develop throughout childhood and are frequently compromised in preterm children, even in those with broadly average global cognitive ability. Risks for deficits in EF in preterm children and attendant problems in learning and psychosocial functioning are higher in those with more extreme prematurity, neonatal complications, and related brain abnormalities...
November 8, 2016: Seminars in Perinatology
https://www.readbyqxmd.com/read/27827940/psychometric-properties-of-a-36-item-version-of-the-stress-management-competency-indicator-tool
#15
Stefano Toderi, Guido Sarchielli
The development of supervisors' behaviours has been proposed as an innovative approach for the reduction of employees' work stress. The UK Health and Safety Executive (HSE) developed the "Stress Management Competency Indicator Tool" (SMCIT), designed to be used within a learning and development intervention. However, its psychometric properties have never been evaluated, and the length of the questionnaire (66 items) limits its practical applicability. We developed a brief 36-item version of the questionnaire, assessed its psychometric properties and studied the relationship with the employees' psychosocial work environment...
November 7, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27825381/cornerstone-program-for-transition-age-youth-with-serious-mental-illness-study-protocol-for-a-randomized-controlled-trial
#16
Michelle R Munson, Andrea Cole, Victoria Stanhope, Steven C Marcus, Mary McKay, James Jaccard, Shelly Ben-David
BACKGROUND: Transition-age youth have elevated rates of mental disorders, and they often do not receive services. This is a serious public health concern, as mental health conditions persist into adulthood. Continuing to engage this population has been a pervasive challenge for the mental health care system worldwide. Few mental health interventions have been developed for transition-age youth, and even fewer have been found to be effective over the transition to adulthood. Cornerstone, a theoretically guided intervention has shown promise for addressing the mental health and psychosocial needs of this population as they emerge into adulthood...
November 8, 2016: Trials
https://www.readbyqxmd.com/read/27820786/self-directed-learning-in-physician-assistant-education-learning-portfolios-in-physician-assistant-programs
#17
Jeremy H Neal, Laura D M Neal
Self-directed learning (SDL) portfolios are underused in the educational process and should be considered by physician assistant (PA) programs. Clinicians such as PAs are responsible for self-identifying their learning needs, competencies, and ongoing educational requirements. This article introduces an outline for SDL in the PA profession, for direct use by learners and indirect use by educators. Without a plan, many professionals may lack the insight, motivation, and knowledge needed to improve their skill set and establish goals for individual lifelong learning...
December 2016: Journal of Physician Assistant Education
https://www.readbyqxmd.com/read/27810867/alternative-realities-faculty-and-student-perceptions-of-instructional-practices-in-laboratory-courses
#18
Christopher W Beck, Lawrence S Blumer
Curricular reform efforts depend on our ability to determine how courses are taught and how instructional practices affect student outcomes. In this study, we developed a 30-question survey on inquiry-based learning and assessment in undergraduate laboratory courses that was administered to 878 students in 54 courses (41 introductory level and 13 upper level) from 20 institutions (four community colleges, 11 liberal arts colleges, and five universities, of which four were minority-serving institutions). On the basis of an exploratory factor analysis, we defined five constructs: metacognition, feedback and assessment, scientific synthesis, science process skills, and instructor-directed teaching...
2016: CBE Life Sciences Education
https://www.readbyqxmd.com/read/27805746/digital-recording-as-a-teaching-and-learning-method-in-the-skills-laboratory
#19
Ingebjørg Strand, Lise Gulbrandsen, Åshild Slettebø, Dagfinn Nåden
AIM AND OBJECTIVES: The aim of this study was to get information on how nursing students react to, think about and learn from digital recording as a learning and teaching method over time. BACKGROUND: Based on the teaching and learning philosophy of the university college, we used digital recording as a tool in our daily sessions in skills laboratory. However, most of the studies referred to in the background review had a duration of from only a few hours to a number of days...
November 2, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27803204/flipping-the-classroom-assessment-of-strategies-to-promote-student-centered-self-directed-learning-in-a-dental-school-course-in-pediatric-dentistry
#20
Brenda S Bohaty, Gloria J Redford, Cynthia C Gadbury-Amyot
The aim of this study was to explore student and course director experiences with the redesign of a traditional lecture-based course into a flipped classroom for teaching didactic content in pediatric dentistry to second-year dental students. The study assessed student satisfaction, extent of student engagement, overall course grades, and course director satisfaction. The students enrolled in a flipped classroom pediatric dentistry course (spring semester 2014; SP14) were asked to complete pre- and post-course questionnaires to assess their perceptions of active learning, knowledge acquisition, and course satisfaction...
November 2016: Journal of Dental Education
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