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https://www.readbyqxmd.com/read/28458740/fabrication-of-a-reticular-poly-lactide-co-glycolide-cylindrical-scaffold-for-the-in-vitro-development-of-microvascular-networks
#1
Yen-Ting Tung, Cheng-Chung Chang, Jyh-Cherng Ju, Gou-Jen Wang
The microvascular network is a simple but critical system that is responsible for a range of important biological mechanisms in the bodies of all animals. The ability to generate a functional microvessel not only makes it possible to engineer vital tissue of considerable size but also serves as a platform for biomedical studies. However, most of the current methods for generating microvessel networks in vitro use rectangular channels which cannot represent real vessels in vivo and have dead zones at their corners, hence hindering the circulation of culture medium...
2017: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/28420469/-heparin-reduces-endothelial-cell-damage-induced-by-neutrophil-extracellular-traps
#2
Yanting Qiao, Jing Jiang, Zhidan Zhang, Xiaochun Ma
OBJECTIVE: Clarify the effect of neutrophil extracellular traps (NETs) on endothelial cell injury, and investigate whether the heparin can exert a protective effect on endothelial cells by reducing the endothelial cell injury induced by NETs. METHODS: Neutrophils (PMN) were obtained from healthy human peripheral blood by Percoll-Histopaque density gradient centrifugation, and was stimulated with phorbol ester (PMA) to induce NETs. The qualitative and quantitative analysis of NETs was detected by immunofluorescence staining combined with fluorescence detector...
April 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28411713/cosmetic-sclerotherapy
#3
Jennifer J Watson, M Ashraf Mansour
Telangiectasias and spider veins are considered a common cosmetic concern for both women and men. Sclerotherapy is a frequently used, low-risk, and highly successful method to treat these venous problems. This article reviews the pathophysiology and diagnosis of telangiectasias and reticular veins as well as the currently available agents and techniques of sclerotherapy. The possible complications and adverse outcomes of sclerotherapy are described. Standard care and follow-up for patients after the procedure are outlined...
May 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/27935886/-adjuvant-phlebotrophic-therapy-and-its-effect-on-anti-inflammatory-response-after-sclerotherapy
#4
RANDOMIZED CONTROLLED TRIAL
V Yu Bogachev, B V Boldin, V N Lobanov, N R Arkadan, M Yu Ermak
The study was aimed at evaluating the degree of the systemic and local inflammatory reaction after sclerotherapy, as well as the effect of micronized purified flavonoid fraction (Detralex) thereupon. The study comprised a total of 60 female patients presenting with reticular veins and telangiectasias (clinical class C1 according to the CEAP classification). The patients were subdivided into two groups, each comprising 30 women. The Study Group patients two weeks prior to the forthcoming sclerotherapy had been taking Detralex prescribed at a daily dose of 1,000 mg whose administration was prolonged by not less than 2 months after the procedure...
2016: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/27911107/endovenous-and-perivenous-808-nm-laser-treatment-of-lower-limb-collateral-reticular-and-telangiectasiac-veins
#5
Walter Bugiantella, Bruno Bovani, Francesco Zini
BACKGROUND: Visible leg veins are not only a mere aesthetic problem, but may also be manifestation of altered microcirculation and superficial venous incompetency. Sclerotherapy is the first-line treatment for leg veins < 4 mm, but it often needs multiple sessions and sometimes fails. The main limitations of transcutaneous laser treatment are the diameter and the depth of the veins: the greater, the harder photothermolysis is, so that higher powers may lead to aesthetic complications...
February 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27738241/evaluation-of-sodium-tetradecyl-sulfate-and-polidocanol-as-sclerosants-for-leg-telangiectasia-based-on-histological-evaluation-with-clinical-correlation
#6
Ronald Bush, Peggy Bush
INTRODUCTION: This study was designed to determine by histological evaluation and clinical correlation the most effective sclerosant concentration of Sotradecol® (sodium tetradecyl sulfate) and Asclera® (polidocanol) for the treatment of leg telangiectasia. METHODS: Histological studies were completed on 40 patients, all of whom were female with a mean age of 53. After sclerotherapy with varying concentrations of sclerosant solutions for the treatment of 0.8 mm and 1 mm leg telangiectasia, histological specimens were examined for the following criteria: luminal changes, subintimal changes, smooth muscle wall alterations, and vessel wall integrity...
October 12, 2016: Phlebology
https://www.readbyqxmd.com/read/27723901/neutrophil-extracellular-traps-in-health-and-disease
#7
Paul Hasler, Stavros Giaglis, Sinuhe Hahn
Polymorphonuclear neutrophil granulocytes are the first responders of the immune system to threats by invading microorganisms. In the traditional view, they combat the intruders by phagocytosis and externalisation of granules containing lytic and microbicidal factors. A dozen years ago, this concept was expanded by the observation that neutrophils may react to bacteria by extruding their nuclear chromosomal DNA with attached nuclear and cytoplasmic constituents to form extracellular reticular structures. Since they trapped and immobilised the microbes, they were designated neutrophil extracellular traps (NETs), and their ensuing cell death NETosis...
2016: Swiss Medical Weekly
https://www.readbyqxmd.com/read/27681276/the-use-of-transillumination-as-a-rational-approach-to-sclerotherapy-and-endovascular-laser-ablation-of-varices-results-in-the-use-of-an-original-instrument
#8
Marco Apperti, Ermenegildo Furino, Antonio Sellitti, Gennaro Quarto
AIM: To explain the mode of using and the obtained results during EVLA procedures and sclerotherapies with support of Visioven®, a laser transillumination instrument. MATERIALS AND METHODS: 205 patients suffering from Chronic Venous Insufficiency - CEAP-C stage 1-2 enrolled (103 females and 102 males) and divided into two groups. A Group: patients candidate for sclerotherapy; B Group: patients to be subjected to endovascular laser ablation (EVLA). In both groups patients were divided into two sub-groups on the basis of the use of Visioven® or not during the procedure...
2016: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/27467230/successful-treatment-of-chronic-venous-ulcers-with-a-1-320-nm-endovenous-laser-combined-with-other-minimally-invasive-venous-procedures
#9
Ashley Wysong, Brent R Taylor, Michael Graves, Vineet Mishra, Ryan Gilbertson, Hubert T Greenway, Leland Housman
BACKGROUND: Venous ulcers are very common with few curative treatment options. OBJECTIVE: To report the closure rate and clinical characteristics of active venous ulcers in a vein clinic using endovenous laser ablation (EVLA) with a 1,320-nm laser. METHODS AND MATERIALS: A prospective database was kept consisting of patients with an active venous ulcer at the time of consultation in a single-practitioner academic vein clinic from March 2007 to May 2014...
August 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27379853/-practical-aspects-of-sclerotherapy
#10
REVIEW
Markus Stücker, Martin Dörler
Sclerotherapy is an important part of the treatment of varicose veins. It may also be performed in patients with contraindications for operative procedures. By adjusting the mode of application (liquid or foam) and the concentration it can be used for the treatment of all vein types. In comparison to other treatment options it is especially well suited for the treatment of spider veins and reticular veins, pudendal varicosity and so called "feeding" varicose veins in the proximity of venous leg ulcers. A current European guideline, which was approved by 23 European phlebologic societies, supports the good international standardization of this treatment technique...
June 2016: Wiener Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27336342/-transitory-evening-venous-reflux-in-patients-with-intracutaneous-varicosity-and-medicamentous-correction-thereof
#11
Yu T Tsukanov, A I Nikolaichuk
The authors carried out a study aimed at revealing transitory refluxes along the great saphenous vein (GSV) in patients with intracutaneous varicosity, and at investigating the possibility of removing them by means of preparations of micronized purified flavonoid fraction (MPFF). The study included a total of one hundred and forty-seven 21-to-47-year-old (mean age 31±4.4 years) women presenting with cutaneous varicosity (class C1s). The duration of skin manifestations amounted to 9.4±3.9 years (varying from 4 to 24 years)...
2016: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/27314532/orthostatic-loading-induced-transient-venous-refluxes-day-orthostatic-loading-test-and-remedial-effect-of-micronized-purified-flavonoid-fraction-in-patients-with-telangiectasia-and-reticular-vein
#12
Yurii T Tsukanov, Aleksandr I Nicolaichuk
BACKGROUND: Orthostatic loading can induce transient venous reflux (TVR). Among patients with telangiectasia and reticular varices, we determined the proportion that developed TVR after a day of orthostatic loading (DOL test), and investigated the remedial effects of micronized purified flavonoid fraction (MPFF). METHODS: All 96 patients enrolled in this study had telangiectasia and reticular varices. Patients underwent duplex scanning (DS)in the morningand evening, and vein diameters were measured...
June 17, 2016: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/27113709/hand-rejuvenation-a-comprehensive-review-of-fat-grafting
#13
REVIEW
Don Hoang, Matthew I Orgel, David A Kulber
Dermal atrophy, bulging reticular veins, and prominent bones and tendons are characteristic of the aging hand. Demand for cosmetic procedures to restore a youthful appearance to the dorsum of the hand has risen in recent years. A review of the literature reveals that of the many options for hand restoration, autologous fat grafting stands out as the most promising choice compared with many available alternative options such as microdermabrasion, peeling agents, and dermal fillers. This article details the surgical technique and relevant anatomy necessary for successful hand rejuvenation...
May 2016: Journal of Hand Surgery
https://www.readbyqxmd.com/read/27104778/safety-concerns-for-sclerotherapy-of-telangiectases-reticular-and-varicose-veins
#14
REVIEW
Eugenia Yiannakopoulou
BACKGROUND: Sclerotherapy has been extensively used in the treatment of valvular insufficiency of superficial veins. Although sclerotherapy seems safe, reports of serious adverse events (AE) have been published. This paper aims to review AE of sclerosing agents. METHODS: Electronical databases were searched for identifying articles on local, serious and long-term AE of sclerotherapy. RESULTS: Hyperpigmentation and matting are the most often local AE of sclerotherapy...
2016: Pharmacology
https://www.readbyqxmd.com/read/26556703/management-of-reticular-veins-and-telangiectases
#15
REVIEW
Philip Coleridge Smith
AIM: To review the literature related to the management of reticular varices and telangiectases of the lower limbs to provide guidance on the treatment of these veins. FINDINGS: Very few randomised clinical trials are available in this field. A European Guideline has been published on the treatment of reticular varices and telangiectases, which is largely based on the opinion of experts. Older accounts written by individual phlebologists contain extensive advice from their own practice, which is valuable in identifying effective methods of sclerotherapy...
November 2015: Phlebology
https://www.readbyqxmd.com/read/26411530/naca-deficiency-reveals-the-crucial-role-of-somite-derived-stromal-cells-in-haematopoietic-niche-formation
#16
Emi Murayama, Milka Sarris, Michael Redd, Dorothée Le Guyader, Catherine Vivier, Wyatt Horsley, Nikolaus Trede, Philippe Herbomel
The ontogeny of haematopoietic niches in vertebrates is essentially unknown. Here we show that the stromal cells of the caudal haematopoietic tissue (CHT), the first niche where definitive haematopoietic stem/progenitor cells (HSPCs) home in zebrafish development, derive from the caudal somites through an epithelial-mesenchymal transition (EMT). The resulting stromal cell progenitors accompany the formation of the caudal vein sinusoids, the other main component of the CHT niche, and mature into reticular cells lining and interconnecting sinusoids...
2015: Nature Communications
https://www.readbyqxmd.com/read/26359998/a-randomized-double-blind-placebo-controlled-study-of-the-effect-of-a-high-potency-topical-corticosteroid-after-sclerotherapy-for-reticular-and-telangiectatic-veins-of-the-lower-extremities
#17
RANDOMIZED CONTROLLED TRIAL
Daniel P Friedmann, Ana M Liolios, Douglas C Wu, Mitchel P Goldman, Sasima Eimpunth
BACKGROUND: Although typically mild, transient, and expected, most adverse events (AEs) postsclerotherapy are inflammatory in nature. OBJECTIVE: To evaluate the effects of a high-potency topical corticosteroid (TC) applied immediately postsclerotherapy. MATERIALS AND METHODS: Subjects undergoing bilateral lower extremity sclerotherapy with polidocanol had extremities randomized to a single application of betamethasone dipropionate and placebo saline solutions immediately post-treatment in a double-blind manner...
October 2015: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/26221338/comparison-of-high-ligation-and-stripping-of-the-great-saphenous-vein-combined-with-foam-sclerotherapy-versus-conventional-surgery-for-the-treatment-of-superficial-venous-varicosities-of-the-lower-extremity
#18
Zi-Yuan Zhao, Xiu-Jun Zhang, Jun-Hai Li, Mei Huang
The aim of this study was to compare the results of high ligation and stripping of the great saphenous vein (GSV) trunk combined with foam sclerotherapy with conventional surgery for the treatment of superficial venous varicosities of the lower extremity. One hundred and thirty eight patients with primary or secondary superficial venous varicosities of the lower extremity were included. 60 underwent conventional surgery and 78 were treated with high ligation and stripping of the GSV trunk and foam sclerotherapy of GSV branches, spider veins, and reticular veins...
2015: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/25813260/-present-and-future-in-the-management-of-venous-vascular-diseases
#19
REVIEW
Peter Gavorník, Andrej Dukát, Ľudovít Gašpar, Eva Gavorníková
The prevalence and the incidence of chronic and acute venous vascular disease has been shown to be globally very high, in both industrialized and developing countries. Chronic venous diseases of lower extremities are being an integral part of the third millennium's deadly angiopandemy, at the present time. The rate of the most severe cases with advanced stage of venous failure is approximately twice as high in the population (2.1 %) as has been assumed so far. Among venoactive drugs (VAD), micronized purified flavonoid fraction (MPFF) of diosmin hesperidin remains the agent with the highest degree of recommendation and it also indicated to pharmacotherapeutical support of leg ulcer healing, along with sulodexide and pentoxifylline...
February 2015: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/25755590/biliary-tract-anatomy-and-its-relationship-with-venous-drainage
#20
REVIEW
Chittapuram S Ramesh Babu, Malay Sharma
Portal cavernoma develops as a bunch of hepatopetal collaterals in response to portomesenteric venous obstruction and induces morphological changes in the biliary ducts, referred to as portal cavernoma cholangiopathy. This article briefly reviews the available literature on the vascular supply of the biliary tract in the light of biliary changes induced by portal cavernoma. Literature pertaining to venous drainage of the biliary tract is scanty whereas more attention was focused on the arterial supply probably because of its significant surgical implications in liver transplantation and development of ischemic changes and strictures in the bile duct due to vasculobiliary injuries...
February 2014: Journal of Clinical and Experimental Hepatology
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