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Cardiac echocardiography

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https://www.readbyqxmd.com/read/29775443/-b-type-natriuretic-peptide-as-a-marker-of-cardiac-dysfunction-in-children-with-chronic-kidney-disease
#1
Tomasz Drożdż, Przemko Kwinta, Zbigniew Kordon, Krystyna Sztefko, Andrzej Rudziński, Katarzyna Zachwieja, Monika Miklaszewska, Danuta Czarnecka, Dorota Drożdż
Left ventricular hypertrophy is the most common organ damage in children with chronic kidney disease (CKD). AIM: The aim of the study was to assess the usefulness of B-type natriuretic peptide (BNP) as a marker of heart injury in children with CKD. MATERIALS AND METHODS: We included 66 children (41 boys and 25 girls) aged 0.7 to 18.6 (median 11.6) years with CKD stage 1-5. The concentrations of urea, creatinine, cystatin C and BNP in blood serum were assessed, and the estimated glomerular filtration rate (eGFR) was calculated from the Schwartz and Filler formulas...
April 23, 2018: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29772401/evaluation-ofserum-free-carnitine-acylcarnitine-levels-and-left-ventricular-systolic-functions-in-children-with-idiopathic-epilepsy-receiving-valproic-acid
#2
Ilknur Kulhas Celik, Haydar Ali Tasdemir, Hülya Ince, Halil Celik, Metin Sungur
OBJECTIVES: In the study, the effect of valproic acid on serum free/acylcarnitine levels and left ventricular systolic function in pediatric patients with idiopathic epilepsy receiving valproic acid was investigated. PATIENTS AND METHODS: Patients receiving valproic acid treatment for six months between January 2012 and December 2012 were evaluated. Blood samples were obtained from the participants twice (pretreatment and the sixth month of treatment) and serum-free and acylcarnitine levels (from C2 to C18:1-OH) were measured using tandem mass spectrometry...
May 14, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29771427/three-dimensional-echocardiography-in-the-diagnosis-of-myocardial-infarction-and-its-correlation-with-the-expressions-of-serum-hif-1%C3%AE-ho-1-and-vegf
#3
Q Yu, L Li, N Zhao
OBJECTIVE: To investigate the correlation between three-dimensional echocardiography and the expressions of hypoxia-inducible factor-1 alpha (HIF-1α), heme oxygenase 1 (HO-1) and vascular endothelial growth factor (VEGF) in patients with myocardial infarction. PATIENTS AND METHODS: A total of 40 patients with acute myocardial infarction treated with three-dimensional echocardiography and 40 patients receiving normal physical examination were selected. According to whether the disease occurred, they were divided into the myocardial infarction group and the normal group...
May 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29769710/jdp2-overexpression-provokes-cardiac-dysfunction-in-mice
#4
Jacqueline Heger, Julia Bornbaum, Alona Würfel, Christian Hill, Nils Brockmann, Renáta Gáspár, János Pálóczi, Zoltán V Varga, Márta Sárközy, Péter Bencsik, Tamás Csont, Szilvia Török, Baktybek Kojonazarov, Ralph Theo Schermuly, Kerstin Böngler, Mariana Parahuleva, Peter Ferdinandy, Rainer Schulz, Gerhild Euler
The transcriptional regulator JDP2 (Jun dimerization protein 2) has been identified as a prognostic marker for patients to develop heart failure after myocardial infarction. We now performed in vivo studies on JDP2-overexpressing mice, to clarify the impact of JDP2 on heart failure progression. Therefore, during birth up to the age of 4 weeks cardiac-specific JDP2 overexpression was prevented by doxycycline feeding in transgenic mice. Then, JDP2 overexpression was started. Already after 1 week, cardiac function, determined by echocardiography, decreased which was also resembled on the cardiomyocyte level...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29769494/clinical-profile-and-outcome-of-peripartum-cardiomyopathy-a-study-in-a-tertiary-cardiac-hospital-of-bangladesh
#5
N Fatema, S K Banerjee, C M Ahmed, A A Habib, F Rahman, S A Ahsan, H Hoque, R C Debnath, S Hashem, J Arzu
This study was done to evaluate the clinical profile, management and to analysis of pregnancy outcomes of peripartum cardiomyopathy pregnant women. Follow up was done after treatment and to see the prognosis. All patients admitted with peripartum cardiomyopathy from July 2009 to June 2014 in the department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh were considered for this observational study. Seventy two (72) women were evaluated. Primi-paras are 28 (39%) of the total study population...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29769130/diagnostic-accuracy-of-low-dose-dual-source-cardiac-computed-tomography-as-compared-to-surgery-in-univentricular-heart-patients
#6
Narumol Chaosuwannakit, Pattarapong Makarawate
BACKGROUND: To evaluate the ability of low radiation dose dual-source computed tomography (DSCT) to depict the features of morphological univentricular heart and to define accuracy by comparing findings with surgery. METHODS: Low radiation dose dual-source cardiac computed tomography (CCT) of 33 cases of functional univentricular heart preliminary diagnosis by echocardiography compared with the results of surgery were retrospectively analyzed (aged 1 day to 4 years, median 5 months)...
May 16, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29767542/optimal-left-ventricular-lead-placement-for-cardiac-resynchronization-therapy-in-postmyocardial-infarction-patients
#7
Carmine Muto, Francesco Solimene, Vincenzo Russo, Gerardo Nigro, Anna Rago, Raffaele Chianese, Paola Chiariello, Carmine Ciardiello, Luigi Caliendo
AIM: To evaluate at a 12-month follow-up, the clinical and echocardiographic outcomes in postmyocardial infarction (MI) heart failure patients who underwent cardiac resynchronization therapy (CRT) device implantation. MATERIALS & METHODS: A total of 100 patients received a CRT device, and the study population was divided into three groups, according to the site of MI and left ventricular (LV) lead placed downstream of the ischemic area, as evaluated by echocardiography...
May 16, 2018: Future Cardiology
https://www.readbyqxmd.com/read/29767239/time%C3%A2-dependent-and-independent-effects-of-thyroid-hormone-administration-following-myocardial-infarction-in-rats
#8
Ioanna Iliopoulou, Iordanis Mourouzis, George I Lambrou, Dimitra Iliopoulou, Dimitrios-Dionysios Koutsouris, Constantinos Pantos
Cardiac function is reduced following myocardial infarction (MI) due to myocardial injury and alterations in the viable non‑ischemic myocardium, a process known as cardiac remodeling. The current treatments available for patients with acute MI (AMI) reduce infarct size, preserve left ventricular (LV) function and improve survival; however, these treatments do not prevent remodeling, which can lead to heart failure. The aim of the present study was to investigate the effects of thyroid hormone (TH) treatment following MI in an in vivo rat model...
May 11, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29766334/a-new-modified-anthropometric-haller-index-obtained-without-radiological-exposure
#9
Andrea Sonaglioni, Massimo Baravelli, Antonio Vincenti, Roberta Trevisan, Maurizio Zompatori, Gian Luigi Nicolosi, Michele Lombardo, Claudio Anzà
To validate a new modified method for measuring the anthropometric Haller index (HI), obtained without radiological exposure. This new method was based on the use of a rigid ruler and of a 2.5 MHz ultrasound transducer for the assessment of latero-lateral and antero-posterior chest diameters, respectively. We enrolled 100 consecutive patients (mean age 67.9 ± 14.5 years, 55% males), who underwent a two-plane CXR, for any clinical indication, over a four-month period. In all patients, the same radiologist calculated the conventional radiological HI (mean value 1...
May 15, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29766272/blood-pressure-is-normal-but-is-the-heart
#10
Serkan Fazlı Çelik, Cemşit Karakurt, Yılmaz Tabel, Taner Elmas, Saim Yoloğlu
BACKGROUND: There is no detailed strain analysis of cardiac functions in treated hypertensive pediatric patients. The aim of this study was to evaluate the cardio-protective effects of different drug classes in treated pediatric hypertensive patients. METHODS: Sixty non-obese-treated hypertensive patients with preserved left ventricular (LV) systolic function and 45 age-, sex-, and body mass index-matched healthy subjects underwent clinical evaluation, including 24-h ambulatory blood pressure monitoring, standard echocardiographic examination, tissue Doppler imaging, and two-dimensional Speckle Tracking Echocardiography...
May 15, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29764969/cardiovascular-phenotype-and-prognosis-of-patients-with-heart-failure-induced-by-cancer-therapy
#11
Wilson Nadruz, Erin West, Morten Sengeløv, Gabriela L Grove, Mário Santos, John D Groarke, Daniel E Forman, Brian Claggett, Hicham Skali, Anju Nohria, Amil M Shah
OBJECTIVE: This study compared the clinical features, cardiac structure and function evaluated by echocardiography, cardiopulmonary response to exercise and long-term clinical outcomes between patients with heart failure (HF) induced by cancer therapy (CTHF) and heart failure not induced by cancer therapy (NCTHF). METHODS: We evaluated 75 patients with CTHF and 894 with NCTHF who underwent clinically indicated cardiopulmonary exercise testing, and followed these individuals for a median of 4...
May 15, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29764968/how-to-prevent-and-manage-radiation-induced-coronary-artery-disease
#12
REVIEW
Jason R Cuomo, Sean P Javaheri, Gyanendra K Sharma, Deepak Kapoor, Adam E Berman, Neal L Weintraub
Radiation-induced coronary heart disease (RICHD) is the second most common cause of morbidity and mortality in patients treated with radiotherapy for breast cancer, Hodgkin's lymphoma and other prevalent mediastinal malignancies. The risk of RICHD increases with radiation dose. Exposed patients may present decades after treatment with manifestations ranging from asymptomatic myocardial perfusion defects to ostial, triple-vessel disease and sudden cardiac death. RICHD is insidious, with a long latency and a tendency to remain silent late into the disease course...
May 15, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29764826/systemic-sclerosis-severe-pulmonary-arterial-hypertension-and-pericardial-effusion-at-diagnosis
#13
Patricia Moniz, Daniel Rei, Joana Rodrigues, Arturo Botella
A 51-year-old female patient with a recent hospital admission reported to the emergency room (ER) with progressive worsening of fatigue, dyspnoea and chest discomfort. She had been recently admitted and discharged with the diagnosis of pericarditis and medicated with non-steroidal anti-inflammatory drugs and diuretics. She returned to the ER with persisting symptoms. Echocardiography was repeated and showed signs of elevated right ventricular systolic pressure and a slightly increased moderate/severe pericardial effusion without signs of cardiac tamponade...
May 14, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29764506/cardiotoxicity-of-5-fluorouracil-and-capecitabine-in-chinese-patients-a-prospective-study
#14
Jianjun Peng, Chao Dong, Chang Wang, Weihua Li, Hao Yu, Min Zhang, Qun Zhao, Bo Zhu, Jun Zhang, Wenliang Li, Fenghua Wang, Qiong Wu, Wenhao Zhou, Ying Yuan, Meng Qiu, Gong Chen
BACKGROUND: 5-Fluorouracil (5-FU) and capecitabine-associated cardiotoxicity ranging from asymptomatic electrocardiography (ECG) abnormalities to severe myocardial infarction has been reported in a number of studies, but such cardiotoxicity in Chinese patients with malignant diseases has not been investigated to date. In the present study, we aimed to prospectively evaluate the incidence rates and clinical manifestations of 5-FU- and capecitabine-associated cardiotoxicity in cancer patients recruited from multiple centers in China...
May 11, 2018: Cancer communications
https://www.readbyqxmd.com/read/29764373/a-subclinical-high-tricuspid-regurgitation-pressure-gradient-independent-of-the-mean-pulmonary-artery-pressure-is-a-risk-factor-for-the-survival-after-living-donor-liver-transplantation
#15
Yosuke Saragai, Akinobu Takaki, Yuzo Umeda, Takashi Matsusaki, Tetsuya Yasunaka, Atsushi Oyama, Ryuji Kaku, Kazufumi Nakamura, Ryuichi Yoshida, Daisuke Nobuoka, Takashi Kuise, Kosei Takagi, Takuya Adachi, Nozomu Wada, Yasuto Takeuchi, Kazuko Koike, Fusao Ikeda, Hideki Onishi, Hidenori Shiraha, Shinichiro Nakamura, Hiroshi Morimatsu, Hiroshi Ito, Toshiyoshi Fujiwara, Takahito Yagi, Hiroyuki Okada
BACKGROUND: Portopulmonary hypertension (POPH) is characterized by pulmonary vasoconstriction, while hepatopulmonary syndrome (HPS) is characterized by vasodilation. Definite POPH is a risk factor for the survival after orthotopic liver transplantation (OLT), as the congestive pressure affects the grafted liver, while subclinical pulmonary hypertension (PH) has been acknowledged as a non-risk factor for deceased donor OLT. Given that PH measurement requires cardiac catheterization, the tricuspid regurgitation pressure gradient (TRPG) measured by echocardiography is used to screen for PH and congestive pressure to the liver...
May 15, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/29762924/early-improvement-in-mitral-regurgitation-after-cardiac-resynchronization-therapy-in-cardiomyopathy-patients
#16
Hakimeh Sadeghian, Masoumeh Lotfi-Tokaldany, Mahdi Montazeri, Ali Kazemi Saeed, Mohammad Sahebjam, Akram Sardari, Gita Ejmalian
BACKGROUND: The study aim was to investigate factors affecting the improvement of mitral regurgitation (MR) severity within 48 hours after cardiac resynchronization therapy (CRT) in patients with cardiomyopathy. METHODS: Sixty-nine cardiomyopathy patients (48 males, 21 females; mean age 59.12 ± 9.66 years) in NYHA functional class ≥III, with left ventricular ejection fraction (LVEF) ≤35%, and QRS duration >120 ms, with MR ≥moderate, were included in the study...
September 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29762920/outcomes-of-a-new-generation-stentless-aortic-valve-a-single-center-experience-with-251-consecutive-implants
#17
Guglielmo Stefanelli, Fabrizio Pirro, Giuseppe Danniballe, Alina Olaru, Marco Meli, Luca Weltert
BACKGROUND: The study aim was to investigate the hemodynamic behavior over time and ease of implant and durability of the Sorin Pericarbon Freedom (SPF)® stentless pericardial aortic xenograft. METHODS: Between March 2003 and April 2010, a total of 251 consecutive, non-selected patients (mean age 70.1 years; range: 17-89 years; 17.1% aged >80 years) received a SPF bioprosthesis as an aortic valve substitute at the authors' institution. All implantations were performed by a single surgeon using a classical, double-line, subcoronary implant technique...
September 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29762841/assessment-of-left-ventricular-systolic-synchrony-and-cardiac-function-in-patients-with-ischemic-heart-disease-by-echocardiography
#18
H-P Qu, P-S Dong, Y-J Song, H-M Wang
OBJECTIVE: To investigate the correlation between left ventricular systolic synchrony and cardiac function in patients with ischemic heart diseases of different degrees by echocardiography. PATIENTS AND METHODS: 84 cases of patients with ischemic heart diseases were consecutively selected including 28 cases of asymptomatic heart failure, 40 cases of mild to moderate heart failure, and 16 cases of severe and refractory heart failure. Interventricular synchrony was evaluated by echocardiography, and the result was expressed by interventricular mechanical delay (IVMD)...
April 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29761889/a-novel-human-s10f-hsp20-mutation-induces-lethal-peripartum-cardiomyopathy
#19
Guan-Sheng Liu, George Gardner, George Adly, Min Jiang, Wen-Feng Cai, Chi Keung Lam, Fawzi Alogaili, Nathan Robbins, Jack Rubinstein, Evangelia G Kranias
Heat shock protein 20 (Hsp20) has been shown to be a critical regulator of cardiomyocyte survival upon cardiac stress. In this study, we investigated the functional significance of a novel human Hsp20 mutation (S10F) in peripartum cardiomyopathy. Previous findings showed that cardiac-specific overexpression of this mutant were associated with reduced autophagy, left ventricular dysfunction and early death in male mice. However, this study indicates that females have normal function with no alterations in autophagy but died within a week after 1-4 pregnancies...
May 15, 2018: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/29761608/effect-of-renal-denervation-on-coronary-flow-reserve-in-patients-with-resistant-hypertension
#20
Sebastian Völz, Bert Andersson, Charlotta Ljungman, Li-Ming Gan, Bengt Rundqvist, Sara Svedlund
Renal denervation (RDN) is a potential modality in the treatment of patients with resistant hypertension (RH) and has shown beneficial effect on a variety of cardiovascular surrogate markers. Coronary flow reserve, as assessed by transthoracic Doppler echocardiography (TDE-CFR) is impaired in patients with hypertension and is an independent predictor of cardiac morbidity. However, data on the effect of RDN on TDE-CFR are scarce. The main objective of this study was to assess the effect of RDN on TDE-CFR. Twenty-six consecutive patients with RH (9 female and 17 male; mean age 62 ± 8 years; mean number of antihypertensive drugs 4·2 ± 1·6) underwent bilateral RDN...
May 14, 2018: Clinical Physiology and Functional Imaging
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