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https://www.readbyqxmd.com/read/27918272/rats-can-acquire-conditional-fear-of-faint-light-leaking-through-the-acrylic-resin-used-to-mount-fiber-optic-cannulas
#1
Adam Eckmier, Willy Daney de Marcillac, Agnès Maître, Thérèse M Jay, Matthew J Sanders, Bill P Godsil
Rodents are exquisitely sensitive to light and optogenetic behavioral experiments routinely introduce light-delivery materials into experimental situations, which raises the possibility that light could leak and influence behavioral performance. We examined whether rats respond to a faint diffusion of light, termed caplight, which emanated through the translucent dental acrylic resin used to affix deep-brain optical cannulas in place. Although rats did not display significant changes in locomotion or rearing to caplight in a darkened open field, they did acquire conditional fear via caplight-footshock pairings...
December 2016: Learning & Memory
https://www.readbyqxmd.com/read/27910536/experimental-study-on-the-fluorescence-spectrum-in-the-near-ultraviolet-and-visible-regions-of-a-carbon-dioxide-gas-cerenkov-medium
#2
Xingyin Guan, Huasi Hu, Zhaohui Song, Hetong Han
We investigated the faint fluorescence spectrum of carbon dioxide in the near-ultraviolet and visible regions using an intense relativistic electron beam accelerator with an energy of 0.2-0.3 MeV. Monte Carlo simulations were carried out in advance to maximize the signal-to-noise ratio and a self-normalization pulse experimental layout was designed to overcome the shot-to-shot fluctuations in different pulses of the accelerator. Ultimately, the relative proportion sequences in the near-ultraviolet and visible regions of a carbon dioxide fluorescence spectrum were successfully obtained for the first time...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27902952/simple-40-k-removal-by-acidified-water-leaching-for-estimating-low-levels-of-radiocesium-in-fishery-products-following-fukushima-dai-ichi-nuclear-power-plant-accident
#3
M Inoue, S Yamashita, K Fujimoto, H Kofuji, S Miki, S Nagao
We developed a simple method for (40)K removal by acidified water leaching combined with ammonium phosphomolybdate coprecipitation, for estimating low levels of radiocesium in Japanese flounder. (40)K removal from ashed samples was approximately 98%, with the radiocesium yield of ~98%. The treatment reduced the γ-spectral baseline to ~1/5 at ground and ~3/100 at underground levels (1.04 and 0.11 cph/keV, respectively). Faint signal of (134)Cs, which is embedded in the Compton continuum of (40)K in an untreated sample, was detected...
November 15, 2016: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/27895693/p-wave-dispersion-on-12-lead-electrocardiography-in-adolescents-with-neurocardiogenic-syncope
#4
Dong-Hyuk Lee, Kyung-Min Lee, Jung-Min Yoon, Jae-Woo Lim, Kyung-Ok Kho, Hong-Ryang Kil, Eun-Jung Cheon
PURPOSE: Neurocardiogenic syncope (NCS) is the most frequent cause of fainting during adolescence. Inappropriate cardiovascular autonomic control may be responsible for this clinical event. The head-up tilt test has been considered a diagnostic standard, but it is cumbersome and has a high false-positive rate. We performed a study to evaluate whether P-wave dispersion (PWD) could be a useful electrocardiographic parameter of cardiac autonomic dysfunction in children with NCS. METHODS: Fifty-four patients with NCS (28 boys and 26 girls; mean age, 12...
November 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/27888538/specific-n-glycan-alterations-are-coupled-in-epithelial-mesenchymal-transition-induced-by-egf-in-ge11-epithelial-cells
#5
Qingsong Xu, Chen Qu, Wenjing Wang, Jianguo Gu, Yuguang Du, Linsheng Song
Epithelial-mesenchymal transition (EMT) is a phenomenon in cancer progression during which cancer cells undergo remarkable alteration acquiring highly invasive property. The aim of this study was to evaluate specific N-glycan alterations during EMT induced by epidermal growth factor (EGF) in GE11 epithelial cells. Herein, we demonstrated that EGF activated epidermal growth factor receptor (EGFR)/Akt/extracellular signal-regulated kinase (ERK) phosphorylation and promoted GE11 cell proliferation. Meanwhile, EGF stimulated the epithelial cells to undergo morphological alteration, destroying cell-cell inter-contact and exhibiting mesenchymal cells higher metastatic potential...
November 26, 2016: Cell Biology International
https://www.readbyqxmd.com/read/27885230/the-implantation-of-a-loop-recorder-to-detect-the-cause-of-pre-syncope-in-an-85-year-old-man
#6
Yasuhisa Iriki, Naoya Oketani, Mitsuru Ohishi
The patient was an-85-year-old man with hypertension and hyperlipidemia. The patient had a history of faintness on standing. He visited our hospital after experiencing chest oppression and pre-syncope in 2015. Brain magnetic resonance imaging and echocardiography did not detect any structural brain or heart disease. Ischemic heart disease was suspected based on the myocardial scintigraphy findings, but coronary angiography revealed no unusual findings. Holter electrocardiography did not reveal the reason for his symptoms...
2016: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/27884718/micro-ct-analysis-of-naturally-arrested-brown-spot-enamel-lesions
#7
Mahdi Shahmoradi, Michael V Swain
OBJECTIVES: The aim of this study was to characterize the mineral density parameters through natural enamel brown spot lesions (BSLs) and to visualize and map their mineral distribution pattern in comparison to enamel whitespot lesions (WSLs). METHODS: Study specimens included seventeen proximal WSLs (ICDAS 1, 2), seventeen proximal BSLs and seventeen sound proximal specimens (ICDAS 0) collected from The Oral Surgery Department at Sydney Dental Hospital, Sydney, Australia...
November 21, 2016: Journal of Dentistry
https://www.readbyqxmd.com/read/27883352/-long-term-prognosis-in-patients-with-vasovagal-syncope-after-pacemaker-implantation
#8
REVIEW
Daria Bałczewska, Krzysztof Kaczmarek, Paweł Ptaszyński, Jerzy K Wranicz, Iwona Cygankiewicz
Patients with syncope, without presence of a structural or primary electrical disease, have a very good prognosis. On the other hand, recurring syncope has a negative impact on quality of life and involves a real risk of physical injuries. Vasovagal syncope usually requires no medical therapy and the most commonly recommended instruction include avoidance of fainting triggers, exercise that mainly provoke leg muscles tension, increase salt consumption and drink indicated amount of fluids. In the case cardioinhibitory type of vasovagal syncope the pacemaker implantation can consider...
November 25, 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27877903/the-novel-functional-nucleic-acid-ired-effectively-regulates-target-genes-following-cytoplasmic-delivery-by-faint-electric-treatment
#9
Mahadi Hasan, Noriko Tarashima, Koki Fujikawa, Takashi Ohgita, Susumu Hama, Tamotsu Tanaka, Hiroyuki Saito, Noriaki Minakawa, Kentaro Kogure
An intelligent shRNA expression device (iRed) contains the minimum essential components needed for shRNA production in cells, and could be a novel tool to regulate target genes. However, general delivery carriers consisting of cationic polymers/lipids could impede function of a newly generated shRNA via electrostatic interaction in the cytoplasm. Recently, we found that faint electric treatment (fET) of cells enhanced delivery of siRNA and functional nucleic acids into the cytoplasm in the absence of delivery carriers...
2016: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/27870584/follow-the-carbon-isotopic-labeling-studies-of-early-earth-aerosol
#10
Raea K Hicks, Douglas A Day, Jose L Jimenez, Margaret A Tolbert
Despite the faint young Sun, early Earth might have been kept warm by an atmosphere containing the greenhouse gases CH4 and CO2 in mixing ratios higher than those found on Earth today. Laboratory and modeling studies suggest that an atmosphere containing these trace gases could lead to the formation of organic aerosol haze due to UV photochemistry. Chemical mechanisms proposed to explain haze formation rely on CH4 as the source of carbon and treat CO2 as a source of oxygen only, but this has not previously been verified experimentally...
November 2016: Astrobiology
https://www.readbyqxmd.com/read/27864807/assessing-the-associations-between-awareness-of-myocardial-infarction-symptoms-socioeconomic-factors-and-cardiovascular-disease-risk-factors-through-regression-models
#11
Phoebe Tran, Murray A Mittleman
There are few studies that consider the association between awareness of symptoms of acute myocardial infarction (MI), socioeconomic factors (household income, sex, race/ethnicity, and educational attainment), and cardiovascular (CVD) risk factors. It is important to understand these associations because there is evidence that suggests that disparities in the awareness of MI symptoms lead to disparities in delays in receiving treatment and outcomes of patients with MI. The study was to determine if there are disparities in the awareness of different MI symptoms among different groups with respect to self-reported race, ethnicity, education, age, and income (i...
November 18, 2016: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/27859225/cd93-as-a-potential-target-in-neovascular-age-related-macular-degeneration
#12
Gian Marco Tosi, Elena Caldi, Barbara Parolini, Paolo Toti, Giovanni Neri, Federica Nardi, Claudio Traversi, Gabriele Cevenini, Davide Marigliani, Elisabetta Nuti, Tommaso Bacci, Federico Galvagni, Maurizio Orlandini
In patients with age-related macular degeneration (AMD), choroidal neovascularization is the major cause of severe visual loss. In these patients, the persistence of neovascular growth despite vascular endothelial growth factor-A blockage needs the discovery of new endothelial cell targets. The glycoprotein CD93, highly expressed in activated endothelial cells, has been recently involved in the regulation of the angiogenic process both as transmembrane and soluble protein. Choroidal neovascular membranes from patients affected by AMD were examined by immunofluorescence using anti-CD93 and anti-von Willebrand factor antibodies...
November 15, 2016: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/27852100/withdrawn-acupuncture-for-neck-disorders
#13
REVIEW
Kien Trinh, Nadine Graham, Dominik Irnich, Ian D Cameron, Mario Forget
BACKGROUND: Neck pain is one of the three most frequently reported complaints of the musculoskeletal system. Treatments for neck pain are varied, as are perceptions of benefit. Acupuncture has been used as an alternative to more conventional treatment for musculoskeletal pain. This review summarises the most current scientific evidence on the effectiveness of acupuncture for acute, subacute and chronic neck pain. This update replaces our 2006 Cochrane review update on this topic. OBJECTIVES: To determine the effects of acupuncture for adults with neck pain, with focus on pain relief, disability or functional measures, patient satisfaction and global perceived effect...
November 17, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27849310/characteristics-of-retinal-neovascularization-in-proliferative-diabetic-retinopathy-imaged-by-optical-coherence-tomography-angiography
#14
Akihiro Ishibazawa, Taiji Nagaoka, Harumasa Yokota, Atsushi Takahashi, Tsuneaki Omae, Young-Seok Song, Tatsuhisa Takahashi, Akitoshi Yoshida
Purpose: To characterize the morphology of neovascularization at the disc (NVD) and neovascularization elsewhere (NVE) in treatment-naïve or previously treated proliferative diabetic retinopathy (PDR) patients using optical coherence tomography (OCT) angiography. Methods: En face OCT angiograms of NVD/NVE in 40 eyes of 33 patients with PDR were acquired using RTVue XR Avanti OCT. The morphology of NVD/NVE on OCT angiograms was evaluated, and the activity was determined by biomicroscopy and fluorescein angiography (FA)...
November 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27847819/acute-mountain-sickness-symptoms-depend-on-normobaric-versus-hypobaric-hypoxia
#15
Dana M DiPasquale, Gary E Strangman, N Stuart Harris, Stephen R Muza
Acute mountain sickness (AMS), characterized by headache, nausea, fatigue, and dizziness when unacclimatized individuals rapidly ascend to high altitude, is exacerbated by exercise and can be disabling. Although AMS is observed in both normobaric (NH) and hypobaric hypoxia (HH), recent evidence suggests that NH and HH produce different physiological responses. We evaluated whether AMS symptoms were different in NH and HH during the initial stages of exposure and if the assessment tool mattered. Seventy-two 8 h exposures to normobaric normoxia (NN), NH, or HH were experienced by 36 subjects...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27844191/-indications-for-implantable-loop-recorders-in-patients-with-channelopathies-and-ventricular-tachycardias
#16
Julia Köbe, Kristina Wasmer, Florian Reinke, Lars Eckardt
Implantable loop recorders (ILR) do not play a pivotal role in the current guidelines on ventricular arrhythmias except in identifying rhythm-symptom correlations if ventricular arrhythmias are assumed. Before a decision for a pure diagnostic implantable device is made, a thorough arrhythmic risk assessment is of major importance due to the potential lethal outcome of ventricular arrhythmias. Nevertheless, some clinical circumstances exist where long-term monitoring by an ILR may add significant information in electrical heart diseases, in patients with ventricular arrhythmias, or structural heart diseases and a potential risk of ventricular arrhythmias...
November 14, 2016: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/27833287/precise-breast-implant-placement-using-percutaneous-chest-wall-markings
#17
Janna Joethy, Bien-Keem Tan
BACKGROUND: Traditionally, pre-operative breast markings are usually made using an indelible marker. These markings are at risk of being removed by pre-operative cleaning, positional changes and parenchymal changes post-incision. We present our approach to breast surgery with rib or intercostal markings using methylene blue. METHODS: Using an indelible marker, markings are made on the breast and the inframammary crease. A blue needle (23 G) mounted on a 1 ml syringe is prepared, and aliquots of 0...
May 2016: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/27822418/inhibition-of-mtorc1-signaling-sensitizes-hepatocellular-carcinoma-cells-to-glycolytic-stress
#18
Xin Zhao, Peng Jiang, Xiang Deng, Zhonghu Li, Feng Tian, Fei Guo, Xiaowu Li, Shuguang Wang
Reprogrammed glucose metabolism, especially glycolysis, is profoundly implicated in tumor development or metastasis. As the interconnectedness and flexibility of metabolic signaling, targeting a metabolic signaling molecule may have limited anti-tumor effects. Here, Gene set enrichment analysis (GSEA) was used to explore the accompanied effectors of glycolysis in hepatocellular carcinoma (HCC). Based on the expression of lactate dehydrogenase A (LDHA), a key enzyme in catalyzing pyruvate into lactate, the glycolytic ability of HCC was defined as low group and high group...
2016: American Journal of Cancer Research
https://www.readbyqxmd.com/read/27822381/clinical-pearls-how-my-patients-taught-me-the-fainting-lark-symptom
#19
A Kuiper, M E van Egmond, M P M Harms, M D Oosterhoff, B van Harten, D A Sival, T J de Koning, M A J Tijssen
BACKGROUND: Compulsive movements, complex tics and stereotypies are frequent, especially among patients with autism or psychomotor retardation. These movements can be difficult to characterize and can mimic other conditions like epileptic seizures or paroxysmal dystonia, particularly when abnormal breathing and cerebral hypoxia are induced. CASE PRESENTATION: We describe an 18-year-old patient with Asperger syndrome who presented with attacks of tonic posturing of the trunk and neck...
2016: Journal of Clinical Movement Disorders
https://www.readbyqxmd.com/read/27815001/immediate-and-transient-faintness-following-a-course-of-foam-sclerotherapy-treatment-for-saphenous-vein-incompetence-in-an-elderly-patient
#20
D Rastel
INTRODUCTION: Adverse effects of sclerotherapy are rare. They are divided into two categories: immediate and delayed. Immediate adverse effects are mainly represented by visual disturbances. We are reporting the case of an immediate transient faintness following two sessions of foam sclerotherapy. OBSERVATION: An 80-year-old active female with superficial chronic venous disorder and no significant medical or surgical backgrounds experienced two similar immediate general adverse events following two sessions of sclerotherapy from a total of five...
November 1, 2016: Journal des Maladies Vasculaires
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