keyword
https://read.qxmd.com/read/38651170/what-triggers-the-coupling-of-proton-transfer-and-electron-transfer-at-the-active-site-of-nitrogenase
#1
JOURNAL ARTICLE
Ian Dance
In converting N2 to NH3 the enzyme nitrogenase utilises 8 electrons and 8 protons in the complete catalytic cycle. The source of the electrons is an Fe4 S4 reductase protein (Fe-protein) which temporarily docks with the MoFe-protein that contains the catalytic active cofactor, FeMo-co, and an electron transfer cluster called the P cluster. The overall mechanism involves 8 repetitions of a cycle in which reduced Fe-protein docks with the MoFe-protein, one electron transfers to the P-cluster, and then to FeMo-co, followed by dissociation of the two proteins and re-reduction of the Fe-protein...
April 23, 2024: Dalton Transactions: An International Journal of Inorganic Chemistry
https://read.qxmd.com/read/38650832/tango1-dances-to-export-of-procollagen-from-the-endoplasmic-reticulum
#2
JOURNAL ARTICLE
Carol M Artlett, Lianne M Connolly
The endoplasmic reticulum (ER) to Golgi secretory pathway is an elegantly complex process whereby protein cargoes are manufactured, folded, and distributed from the ER to the cisternal layers of the Golgi stack before they are delivered to their final destinations. The export of large bulky cargoes such as procollagen and its trafficking to the Golgi is a sophisticated mechanism requiring TANGO1 (Transport ANd Golgi Organization protein 1. It is also called MIA3 (Melanoma Inhibitory Activity protein 3). TANGO1 has two prominent isoforms, TANGO1-Long and TANGO1-Short, and each isoform has specific functions...
December 2023: Fibrosis (Hong Kong)
https://read.qxmd.com/read/38643016/art-therapies-and-cognitive-function-in-elderly-with-subjective-cognitive-decline-a-protocol-for-a-network-meta-analysis
#3
JOURNAL ARTICLE
Qian Liu, Fang Wang, Lixia Tan, Li Liu, Xiuying Hu
INTRODUCTION: Subjective cognitive decline means a decline in the subjective perception of self-cognitive function, which is likely to evolve into mild cognitive impairment and dementia. The number of elderly with subjective cognitive decline has increased, bringing huge burdens and challenges to caregivers and society. With the increase in research on art therapies, some of them have gradually been proven to be effective for cognitive function. Therefore, this study aims to summarise the evidence and identify the best art therapy for elderly with subjective cognitive decline...
April 19, 2024: BMJ Open
https://read.qxmd.com/read/38642883/binding-evolution-of-the-dengue-virus-envelope-against-dc-sign-a-combined-approach-of-phylogenetics-and-molecular-dynamics-analyses-over-30-years-of-dengue-virus-in-brazil
#4
JOURNAL ARTICLE
André Berndt Penteado, Geovani de Oliveira Ribeiro, Emerson Luiz Lima Araújo, Rodrigo Bentes Kato, Caio Cesar de Melo Freire, Joselio Maria Galvão de Araújo, Gabriel da Luz Wallau, Richard Steiner Salvato, Ronaldo de Jesus, Geraldine Goés Bosco, Helena Ferreira Franz, Pedro Eduardo Almeida da Silva, Elcio de Souza Leal, Gustavo Henrique Goulart Trossini, Daniel Ferreira de Lima Neto
The Red Queen Hypothesis (RQH), derived from Lewis Carroll's "Through the Looking-Glass", postulates that organisms must continually adapt in response to each other to maintain relative fitness. Within the context of host-pathogen interactions, the RQH implies an evolutionary arms race, wherein viruses evolve to exploit hosts and hosts evolve to resist viral invasion. This study delves into the dynamics of the RQH in the context of virus-cell interactions, specifically focusing on virus receptors and cell receptors...
April 18, 2024: Journal of Molecular Biology
https://read.qxmd.com/read/38640093/the-effects-of-dance-interventions-on-physical-function-and-quality-of-life-among-middle-aged-and-older-adults-a-systematic-review
#5
JOURNAL ARTICLE
Jingting Lu, Nur Athirah Abd Rahman, Matthew Wyon, Shazlin Shaharudin
BACKGROUND: Fundamental physical functions such as postural control and balance are vital in preserving everyday life, affecting an individual's quality of life. Dance is a physical activity that offers health advantages across various life stages. Nevertheless, the effects of dance interventions on physical function, postural control, and quality of life among older adults have remained underexplored. The review aimed to examine the strength of evidence for dance interventions on physical function and quality of life among middle-aged and older adults...
2024: PloS One
https://read.qxmd.com/read/38637156/describing-the-food-choices-of-aboriginal-children-attending-an-afterschool-cultural-program-from-two-different-knowledge-systems-the-importance-of-country-community-and-kinship
#6
JOURNAL ARTICLE
Yasmine Probst, Anthony McKnight, Gabrielle O'Flynn, Sarah Tillott, Rebecca M Stanley
AIMS: This study describes a program co-created with Aboriginal communities to strengthen cultural ties with the children. Food data are reported from two knowledge systems (lenses): Western and Aboriginal relational, focused on Country, community, and kinship. METHODS: A cultural program was undertaken with primary school children of Aboriginal heritage, on Yuin nation, over 10 weeks including culturally appropriate practices (painting, bushtucker, and dance)...
April 18, 2024: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://read.qxmd.com/read/38635740/aoa-critical-issues-symposium-advancing-diversity-equity-and-inclusion-in-orthopaedic-surgery
#7
JOURNAL ARTICLE
Sean A Tabaie, Sarah Dance, Matthew Schmitz, Lisa Lattanza, Addisu Mesfin
In recent years, the medical field has recognized the pivotal role of diversity, equity, and inclusion (DEI) in enhancing patient care and addressing health-care disparities. Orthopaedic surgery has embraced these principles to create a more inclusive and representative workforce. A DEI symposium that was sponsored by the American Orthopaedic Association convened orthopaedic surgeons, researchers, educators, and stakeholders to discuss challenges and strategies for implementing DEI initiatives. The symposium emphasized the importance of equity, and fostered conversations on creating equal opportunities and resources...
April 18, 2024: Journal of Bone and Joint Surgery. American Volume
https://read.qxmd.com/read/38635312/lesions-in-a-songbird-vocal-circuit-increase-variability-in-song-syntax
#8
JOURNAL ARTICLE
Avani Koparkar, Timothy L Warren, Jonathan D Charlesworth, Sooyoon Shin, Michael S Brainard, Lena Veit
Complex skills like speech and dance are composed of ordered sequences of simpler elements, but the neuronal basis for the syntactic ordering of actions is poorly understood. Birdsong is a learned vocal behavior composed of syntactically ordered syllables, controlled in part by the songbird premotor nucleus HVC (proper name). Here, we test whether one of HVC's recurrent inputs, mMAN (medial magnocellular nucleus of the anterior nidopallium), contributes to sequencing in adult male Bengalese finches ( Lonchura striata domestica )...
April 18, 2024: ELife
https://read.qxmd.com/read/38634549/an-odd-dancing-couple-non-small-cell-lung-carcinoma-with-coexisting-egfr-mutation-and-ntrk-1-translocation-a-case-report
#9
JOURNAL ARTICLE
Ramon Robledano, Maria D Lozano
In the 21st century, there has been a dramatic shift in the diagnosis and management of non-small cell lung carcinoma (NSCLC), with an increasing use of minimally invasive tissue acquisition methods. Current treatments require morphologic subtyping and biomarker information in all cases. Determining such biomarkers is a continuously evolving field; current guidelines state that the determination of mutations on the Epidermal Growth Factor (EFGR), Kirsten Rat Sarcoma viral oncogene homolog (KRAS), Proto-oncogene B-Raf (BRAF), Human epidermal growth factor receptor 2 (HER2) and Anaplastic Lymphoma Kinase (ALK), genes as well as fusions on genes such as ROS Proto-Oncogene 1, Receptor Tyrosine Kinase (ROS1), MET proto-oncogene, receptor tyrosine kinase (MET), RET proto-oncogene (RET), and the Neurotrophic Tyrosine Receptor Kinase (NTRK) family is mandatory...
April 18, 2024: Diagnostic Cytopathology
https://read.qxmd.com/read/38633130/chronic-myeloproliferative-neoplasm-in-adulthood-in-cbl-syndrome-harboring-a-splice-site-cbl-variant-alongside-a-novel-constitutional-csf3r-variant
#10
George Mason, Rhian Aghajani, Brieanna Dance, Jad Othman, Linda Goodwin, William Stevenson, Naomi Mackinlay
Casitas B-cell lineage (CBL) syndrome is a rare RASopathy known to predispose to CBL-mutated juvenile myelomonocytic leukemia (JMML) in childhood. Adulthood acute myeloid leukemia arising out of a genetic aberrancies consistent with prior CBL-mutated JMML has been twice previously described, but chronic myeloproliferative neoplasia has not. We present a case of progressive myeloproliferative neoplasm in adulthood in the context of CBL syndrome alongside a novel CSF3R variant. We also review pathogenic splice-site mutations in CBL-mutated JMML...
April 2024: EJHaem
https://read.qxmd.com/read/38632997/machine-learning-assisted-novel-recyclable-flexible-triboelectric-nanogenerators-for-intelligent-motion
#11
JOURNAL ARTICLE
Yuzhang Wen, Fengxin Sun, Zhenning Xie, Mengqi Zhang, Zida An, Bing Liu, Yuning Sun, Fei Wang, Yupeng Mao
In the smart era, big data analysis based on sensor units is important in intelligent motion. In this study, a dance sports and injury monitoring system (DIMS) based on a recyclable flexible triboelectric nanogenerator (RF-TENG) sensor module, a data processing hardware module, and an upper computer intelligent analysis module are developed to promote intelligent motion. The resultant RF-TENG exhibits an ultra-fast response time of 17 ms, coupled with robust stability demonstrated over 4200 operational cycles, with 6% variation in output voltage...
April 19, 2024: IScience
https://read.qxmd.com/read/38627000/the-dance
#12
JOURNAL ARTICLE
Andrew Lodge
No abstract text is available yet for this article.
April 2024: Canadian Family Physician Médecin de Famille Canadien
https://read.qxmd.com/read/38622946/dance-with-the-senses-a-dance-class-with-visual-impaired-and-sighted-children-in-a-conservatory-one-year-experience
#13
JOURNAL ARTICLE
Anne-Violette Bruyneel, Lucy Nightingale
BACKGROUND: Children with visual impairment very often have additional motor disorders and developmental delays. They are less active than typical children of a similar age, even though physical activity is essential for their well-being. METHODS: A weekly dance class for 1 year was offered to 4 visually impaired and 5 sighted children in a conservatory. RESULTS: The children's satisfaction was excellent, and they perceived an improvement in their mood, walking, balance and coordination, and felt more physically active...
April 15, 2024: Arts & Health
https://read.qxmd.com/read/38622900/the-use-of-dance-and-movement-for-the-embodied-healing-of-interpersonal-trauma-in-women-and-girls-a-systematic-review
#14
REVIEW
Catherine X Liang, Thema Bryant
Interpersonal trauma is a pervasive issue with devastating consequences for women and girls of diverse identities. Research has shown that there are many potential physiological consequences for experiencing trauma, and as such, treatment for trauma should incorporate the body. Dance/Movement Therapy (DMT) has been emerging in the current literature as one body-oriented treatment approach effective in helping women and girls heal from interpersonal trauma. This review uses textual narrative evidence synthesis to examine how practitioners are currently using DMT for this population, what treatment outcomes have been observed, and what the racial/ethnic identities and international contexts are for survivors who have benefited from DMT...
April 15, 2024: Trauma, Violence & Abuse
https://read.qxmd.com/read/38618855/complex-interventions-for-a-complex-system-using-systems-thinking-to-explore-ways-to-address-unhealthy-commodity-industry-influence-on-public-health-policy
#15
JOURNAL ARTICLE
Adam Bertscher, Britta Katharina Matthes, James Nobles, Anna Gilmore, Krista Bondy, Amber Van Den Akker, Sarah Dance, Michael Bloomfield, Mateusz Zatoński
BACKGROUND: Interventions are needed to prevent and mitigate unhealthy commodity industry (UCI) influence on public health policy. Whilst literature on interventions is emerging, current conceptualisations remain incomplete as they lack considerations of the wider systemic complexities surrounding UCI influence, which may limit intervention effectiveness. This study applies systems thinking as a theoretical lens to help identify and explore how possible interventions relate to one another in the systems in which they are embedded...
February 27, 2024: International Journal of Health Policy and Management
https://read.qxmd.com/read/38618848/building-a-systems-map-applying-systems-thinking-to-unhealthy-commodity-industry-influence-on-public-health-policy
#16
JOURNAL ARTICLE
Adam Bertscher, James Nobles, Anna Gilmore, Krista Bondy, Amber Van Den Akker, Sarah Dance, Michael Bloomfield, Mateusz Zatoński
BACKGROUND: Unhealthy commodity industries (UCIs) engage in political practices to influence public health policy, which poses barriers to protecting and promoting public health. Such influence exhibits characteristics of a complex system. Systems thinking would therefore appear to be a useful lens through which to study this phenomenon, potentially deepening our understanding of how UCI influence are interconnected with one another through their underlying political, economic and social structures...
March 13, 2024: International Journal of Health Policy and Management
https://read.qxmd.com/read/38617830/dancing-out-of-step-a-case-of-tuberculous-meningitis-presenting-as-childhood-chorea
#17
Jao Jarro B Garcia, Cherie Marie A Tecson-Delos Santos
BACKGROUND: Acute to subacute pediatric movement disorders require prompt diagnosis to identify potentially treatable diseases. CASE REPORT: We present a 6-year-old male with a three-week history of generalized chorea transitioning to predominantly right-sided hemichorea and then to left hemiplegia. DISCUSSION: We review the mechanisms in tuberculous meningitis underlying his movement abnormalities.
2024: Tremor and Other Hyperkinetic Movements
https://read.qxmd.com/read/38616540/cueing-dancers-to-externally-rotate-from-the-hips-improves-potentially-injurious-ankle-joint-angles-and-contact-forces-during-a-demipointe-ballet-position
#18
JOURNAL ARTICLE
Tessa Hulburt, Laura Santos, Katherine Moos, David Popoli, Kristen Nicholson
Introduction: The demipointe dance position puts the ankle at high risk of overuse injury and posteromedial ankle pain due to increased ankle valgus forces. Previous work has shown that creating lower limb external rotation intrinsic to demipointe with hip external rotation reduces foot pronation that causes ankle valgus stress. Therefore, the purpose of this work was to examine long axis rotation kinematics of the hip, knee, and ankle as well as the ankle joint contact forces in demipointe to better understand the biomechanical impact(s) of the specific cue to increase hip external rotation in this position...
April 14, 2024: Journal of Dance Medicine & Science
https://read.qxmd.com/read/38608509/target-analysis-of-psychoactive-drugs-in-oral-fluid-by-quechers-extraction-and-lc-ms-ms
#19
JOURNAL ARTICLE
Ettore Ferrari Júnior, Victor Souza Bitencourt, Ágatha Beatriz Mariano de Souza, Eloisa Dutra Caldas
This study aimed to validate a modified QuEChERS method, followed by liquid chromatography-tandem mass spectrometry, for the determination of 51 psychoactive substances and screening of 22 ones in oral fluid from electronic dance music party (EDM) attendees. Unstimulated oral fluid was collected in a polypropylene tube and stored in a glass vial at -20 ºC. The sample was extracted with acetonitrile:water and MgSO4 /NaOAc, followed by cleanup with primary secondary amine and MgSO4 . The effectiveness of the sample storage conditions was shown to be comparable to when the Quantisal™ buffer was used, with no substantial concentration loss (< 15%) for all the substances after up to 72 hours at -20º C...
April 8, 2024: Journal of Pharmaceutical and Biomedical Analysis
https://read.qxmd.com/read/38606116/embodied-collaborative-writing-in-graduate-dance-education
#20
JOURNAL ARTICLE
Pirkko Markula, Janita Frantsi
This paper explores how embodied writing can inform teaching, learning, and research presentation in graduate-level dance education in a kinesiology faculty. The focus is on a graduate dance course "The Dancing Body in Motion", which combines the anatomical analysis of the physical body, social theory, and lived dance experiences to promote more embodied and holistic teaching and learning. The authors, an instructor and a student of the course, share their experiences and reflections on the course through an embodied presentation of a dialogue that combines the instructor's lecture notes, the student's learning journal entries, and their reflections both separately and in conversation with each other...
2024: Frontiers in sports and active living
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