keyword
MENU ▼
Read by QxMD icon Read
search

thyroid pathology

keyword
https://www.readbyqxmd.com/read/29240719/pericardial-effusion-as-a-presenting-symptom-of-hashimoto-thyroiditis-a-case-report
#1
Alberto Leonardi, Laura Penta, Marta Cofini, Lucia Lanciotti, Nicola Principi, Susanna Esposito
Background: Hashimoto thyroiditis (HT) is the most frequent cause of acquired hypothyroidism in paediatrics. HT is usually diagnosed in older children and adolescents, mainly in females and is rare in infants and toddlers with cardiac involvement, including pericardial effusion, that can be found in 10% to 30% of adult HT cases. In this paper, a child with HT and pericardial effusion as the most important sign of HT is described. Case presentation: A four-year-old male child suffering for a few months from recurrent abdominal pain sometimes associated with vomiting underwent an abdominal ultrasound scan outside the hospital...
December 14, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29239042/special-types-of-thyroid-carcinoma
#2
REVIEW
Zubair W Baloch, Virginia A LiVolsi
This article reviews the small percentage of thyroid tumours that are not classified as classic papillary thyroid carcinoma, follicular thyroid carcinoma, and medullary thyroid carcinoma. It includes subtypes of papillary thyroid carcinoma, including, tall-cell, hobnail/micropapillary, columnar cell, diffuse sclerosing and solid variants. Poorly differentiated carcinoma, high-grade carcinoma and anaplastic thyroid carcinoma are reviewed. Also discussed are entities that are unusual but need to be recognized as primary thyroid neoplasms, i...
January 2018: Histopathology
https://www.readbyqxmd.com/read/29239041/hereditary-and-familial-thyroid-tumours
#3
REVIEW
Julie Guilmette, Vania Nosé
The worldwide incidence of thyroid malignancies has been increasing rapidly. Sensitive imaging modalities and early detection of thyroid lesions have made thyroid cancers the most rapidly increasing cancers in the USA in 2017 (SEER Cancer Facts, 2017). Clinical awareness of potential risk factors, such as inherited thyroid cancers, has allowed earlier recognition of more vulnerable population clusters. Hereditary thyroid neoplasms arising from calcitonin-producing C cells are known as familial medullary thyroid carcinomas (FMTCs), and include well-documented syndromes such as multiple endocrine neoplasia IIA or IIB, and pure familial medullary thyroid carcinoma syndrome...
January 2018: Histopathology
https://www.readbyqxmd.com/read/29239040/molecular-pathology-of-thyroid-tumours-of-follicular-cells-a-review-of-genetic-alterations-and-their-clinicopathological-relevance
#4
REVIEW
Giorgia Acquaviva, Michela Visani, Andrea Repaci, Kerry J Rhoden, Dario de Biase, Annalisa Pession, Tallini Giovanni
Thyroid cancer is the most common endocrine malignancy. Knowledge of the molecular pathology of thyroid tumours originating from follicular cells has greatly advanced in the past several years. Common molecular alterations, such as BRAF p.V600E, RAS point mutations, and fusion oncogenes (RET-PTC being the prototypical example), have been, respectively, associated with conventional papillary carcinoma, follicular-patterned tumours (follicular adenoma, follicular carcinoma, and the follicular variant of papillary carcinoma/non-invasive follicular thyroid neoplasm with papillary-like nuclear features), and with papillary carcinomas from young patients and arising after exposure to ionising radiation, respectively...
January 2018: Histopathology
https://www.readbyqxmd.com/read/29239033/what-s-new-in-pituitary-pathology
#5
REVIEW
Sylvia L Asa, Ozgur Mete
The increasing recognition of pituitary disorders and their impact on quality of life and longevity has made understanding of this small gland a subject of paramount importance. Pituitary pathology has seen many significant studies that indicate progress in identification and classification of pituitary lesions, as well as improved management strategies for patients. In this review, we outline six major areas of advances: (i) changes in terminology from 'adenoma' to 'pituitary neuroendocrine tumour'; (ii) reclassification of hormone-negative tumours based on transcription factor expression that defines lineage; (iii) updates in new pathogenetic mechanisms, including those that underlie rare lesions such as X-LAG and pituitary blastoma; (iv) clarification of hypophysitis due to immunotherapy, xanthomatous hypophysitis due to rupture of a Rathke's cleft cyst and IgG4 disease as the cause of inflammatory pseudotumour; (v) the consolidation of pituicytoma variants, including spindle cell oncocytoma and granular cell tumour based on thyroid transcription factor-1 (TTF-1) reactivity; and (vi) the pathogenetic mechanisms that distinguish papillary from adamantinomatous craniopharyngioma...
January 2018: Histopathology
https://www.readbyqxmd.com/read/29235733/intraoperative-parathyroid-aspiration-and-parathyroid-hormone-assay-during-parathyroidectomy-for-primary-hyperparathyroidism
#6
Miki Paker, Shani Fisher, Salim Mazzawi, Raul Kolodner, Dror Ashkenazi
BACKGROUND: Direct aspiration from suspected pathological tissue and rapid parathyroid hormone analysis may offer a reliable, cost effective alternative to currently used "gold standard" tests. OBJECTIVES: To validate the accuracy of intraoperative measurements of parathyroid hormone levels in parathyroid adenomas. METHODS: A prospective study included 22 patients diagnosed with primary hyperparathyroidism who underwent parathyroidectomy due to an adenoma or hyperplasia...
December 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29234625/insight-into-differentiated-thyroid-cancer-gross-pathological-specimen-shrinkage-and-its-influence-on-tnm-staging
#7
Alexis Lacout, Emmanuel Chamorey, Juliette Thariat, Mostafa El Hajjam, Carole Chevenet, Renaud Schiappa, Pierre Yves Marcy
Introduction: This study aimed at comparing thyroid cancer staging when taking into account the differences between the "T" assessment" using ultrasound (US) and histopathological measurements. Material and Methods: This retrospective study included all consecutive differentiated follicular thyroid cancer (DTC) and medullary thyroid cancer (MTC) patients who underwent postoperative histopathological staging assessment at a single institution. Anaplastic thyroid carcinomas were excluded from the present study...
November 2017: European Thyroid Journal
https://www.readbyqxmd.com/read/29229118/clinical-predictors-of-lymph-node-metastasis-and-survival-rate-in-papillary-thyroid-microcarcinoma-analysis-of-3607-patients-at-a-single-institution
#8
Yanan Xu, Le Xu, Jiadong Wang
BACKGROUND: The treatment of papillary thyroid microcarcinoma (PTMC) patients is controversial, as PTMC is often found incidentally and its prognosis is quite good. Because lymph node metastasis (LNM) is one of the main predictors of recurrence and impacts the survival rate of PTMC patients, this study aims to retrospectively identify the clinical factors that increase the risk of LNM and/or recurrence and can then be used to separate clinically unfavorable PTMCs from the rest and to help guide their treatment accordingly...
January 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29228030/logistic-regression-analysis-of-conventional-ultrasonography-strain-elastosonography-and-contrast-enhanced-ultrasound-characteristics-for-the-differentiation-of-benign-and-malignant-thyroid-nodules
#9
Tiantian Pang, Leidan Huang, Yingyuan Deng, Tianfu Wang, Siping Chen, Xuehao Gong, Weixiang Liu
The aim of the study is to screen the significant sonographic features by logistic regression analysis and fit a model to diagnose thyroid nodules. A total of 525 pathological thyroid nodules were retrospectively analyzed. All the nodules underwent conventional ultrasonography (US), strain elastosonography (SE), and contrast -enhanced ultrasound (CEUS). Those nodules' 12 suspicious sonographic features were used to assess thyroid nodules. The significant features of diagnosing thyroid nodules were picked out by logistic regression analysis...
2017: PloS One
https://www.readbyqxmd.com/read/29225207/parathyroid-carcinoma-occurred-in-two-glands-in-multiple-endocrine-neoplasia-1-a-report-on-a-rare-case
#10
Yoko Omi, Kiyomi Horiuchi, Kento Haniu, Momoko Tokura, Erin Nagai, Osamu Isozaki, Yoji Nagashima, Takahiro Okamoto
Primary hyperparathyroidism is the most common hormonal manifestation associated with multiple endocrine neoplasia 1 (MEN1). It is generally caused by parathyroid hyperplasia, and parathyroid carcinoma is rare. Here, we report a case of MEN1 with parathyroid carcinoma in two parathyroid glands causing primary hyperparathyroidism. A 40-year-old man with primary hyperparathyroidism due to MEN1 underwent a total parathyroidectomy. His corrected calcium and intact PTH (i-PTH) serum levels were 10.8 mg/dL and 203 pg/mL, respectively...
December 8, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/29224804/clinical-implications-of-pathologic-factors-after-thyroid-lobectomy-in-patients-with-papillary-thyroid-carcinoma
#11
Young Min Park, Doh Young Lee, Kyung Ho Oh, Jae-Gu Cho, Seung-Kuk Baek, Soon-Young Kwon, Kwang-Yoon Jung, Jeong-Soo Woo
OBJECTIVE: We evaluated the clinical and prognostic significance of pathologic factors by analyzing the treatment results of patients who underwent thyroid lobectomy. MATERIALS AND METHODS: We retrospectively analyzed data from 734 patients diagnosed with papillary thyroid cancer who underwent thyroid lobectomy at Korea University Hospital from January 2004 to December 2016. RESULTS: A total of 734 patients were included in the study and their mean age was 44...
December 2017: Oral Oncology
https://www.readbyqxmd.com/read/29214321/hemithyroidectomy-for-low-risk-follicular-carcinoma-of-thyroid-results-from-a-regional-hospital
#12
Tam-Lin Chow, Susanna Wai-Yin Tam, Chi-Yee Choi, Wilson Wai-Yin Kwan
INTRODUCTION: Excellent outcome after conservative thyroid surgery for low-risk follicular thyroid carcinoma (FTC) has been reported from highly specialised centres. However, it is uncertain whether similar treatment results can be achieved in low-volume hospitals. METHODS: At our institution, 49 patients with FTC were treated during 1991-2014. Patients with minimally invasive FTC (MIFTC) were usually treated with hemithyroidectomy. The demographic data, pathology, treatment modality and oncological outcomes of these patients were retrospectively evaluated...
December 7, 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/29208984/a-nonlinear-approach-to-identify-pathological-change-of-thyroid-nodules-based-on-statistical-analysis-of-ultrasound-rf-signals
#13
Huan Xu, Chunrui Liu, Ping Yang, Juan Tu, Bin Yang, Dong Zhang
In order to reassure the majority of patients with benign nodules from unnecessary needle biopsy, there is an increasing clinical requirement to identify benign and malignant thyroid nodules during ultrasound diagnosis. A nonlinear approach based on statistical analysis of ultrasound radio-frequency (RF) signals was developed for differential diagnosing the thyroid nodules to improve the diagnostic accuracy. Data from 44 patients with solitary thyroid nodules were collected, following with the ultrasound-guided fine needle aspiration (FNA) as the ground truth...
December 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29197093/the-association-between-irisin-and-muscle-metabolism-in-different-thyroid-disorders
#14
Ariadna Zybek-Kocik, Nadia Sawicka-Gutaj, Ewelina Szczepanek-Parulska, Mirosław Andrusiewicz, Joanna Waligórska-Stachura, Piotr Białas, Tomasz Krauze, Przemysław Guzik, Jerzy Skrobisz, Marek Ruchała
BACKGROUND: Irisin is a new adipo-myokine, encoded by the FNDC5 gene. Currently, there is a discussion regarding the relation between thyroid function and irisin concentration. This prospective study assesses the influence of thyrometabolic changes on serum irisin concentration in association with altered muscle metabolism. This is performed on a large cohort of patients affected by severe hypo- or hyperthyroidism, as well as by the expression of the FNDC5 gene in thyroid tissue affected by different pathologies...
December 2, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29193941/-findings-of-thyroid-nodules-in-autopsies-in-western-mexico
#15
Luis Ricardo Ramírez-González, Ricardo Sevilla-Vizcaíno, Paulina Monge-Reyes, Jaime Ernesto Aldaz-Dorantes, Aida Rebeca Márquez-Valdez, David García-Martínez, Alejandro González-Ojeda, Clotilde Fuentes-Orozco, Marisol Ramírez-Anaya, Silvia Reyna-Téllez, Octavio Villanueva-Sánchez
BACKGROUND: International literature reports a prevalence of 50% of thyroid nodules detected during autopsies of subjects without known thyroid disease. Currently there are no studies of this type in Mexico. The aim was to identify the prevalence of thyroid nodules in autopsied bodies without known thyroid pathology. METHODS: A series of cases of 300 cadavers without known thyroid pathology, from which we obtained their thyroid glands. It was analyzed the presence of thyroid nodules as well as their macroscopic and microscopic characteristics...
September 2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29193910/does-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-have-distinctive-features-on-sonography
#16
Tamar C Brandler, Joseph Yee, Fang Zhou, Margaret Cho, Joan Cangiarella, Xiao-Jun Wei, Melissa Yee-Chang, Wei Sun
BACKGROUND: The noninvasive encapsulated follicular variant of papillary carcinoma (nEFVPTC) has recently been reclassified to "noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP)," removing this entity from the malignant category. This re-categorization has had major implications for clinical management. NIFTP has overlapping cytohistologic features with papillary thyroid carcinoma (PTC) and with follicular adenomas (FA), but sonographic data comparing NIFTP to PTC and FA is lacking...
November 29, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29189861/-study-and-management-of-thyroid-nodes-by-non-specialist-physicians-soched-consensus
#17
Hernán Tala, René E Díaz, José Miguel Domínguez Ruiz-Tagle, Jorge Sapunar Zenteno, Pedro Pineda, Patricia Arroyo Albala, Marcela Barberán, Patricio Cabané, Francisco Cruz Olivos, Patricio Gac E, Andrea Glasinovic Pizarro, Hernán E González, Francisca Grob, Maria Soledad Hidalgo Valle, Rodrigo Jaimovich, Alejandra Lanas, Claudio Liberman, Maite Lobo Guiñez, Arturo Madrid
The thyroid nodule is a frequent cause of primary care consultation. The prevalence of a palpable thyroid nodule is approximately 4-7%, increasing up to 67% by the incidental detection of nodules on ultrasound. The vast majority are benign and asymptomatic, staying stable over time. The clinical importance of studying a thyroid nodule is to exclude thyroid cancer, which occurs in 5 to 10% of the nodules. The Board of SOCHED (Chilean Society of Endocrinology and Diabetes) asked the Thyroid Study Group to develop a consensus regarding the diagnostic management of the thyroid nodule in Chile, aimed at non-specialist physicians and adapted to the national reality...
August 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29189376/clinical-significance-of-a-solitary-cold-thyroid-nodule-in-the-setting-of-graves-disease
#18
Dwight M Achong
I-NaI thyroid uptake and scan in a 46-year-old woman with symptomatic hyperthyroidism demonstrated marked, diffusely increased uptake consistent with Graves disease, as well as a solitary hypofunctioning ("cold") nodule. Pathologic evaluation following total thyroidectomy and selective neck dissection revealed invasive multifocal papillary thyroid carcinoma in a background of Graves disease and 5 of 36 lymph nodes positive for metastatic disease. This case serves as a reminder that when present a cold nodule in the setting of Graves disease warrants further evaluation for underlying malignancy...
November 17, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29189171/inappropriate-sinus-tachycardia
#19
Mohammed Ruzieh, Abdelmoniem Moustafa, Ebrahim Sabbagh, Mohammad M. Karim, Saima Karim
Definition and diagnosis: Inappropriate Sinus Tachycardia (IST) is a clinical syndrome characterized by a sinus heart rate inexplicably higher than one hundred beats per minute at rest that is associated with symptoms like palpitations, dyspnea or dizziness in the absence of primary causes of tachycardia. The diagnosis requires exclusion of other causes of tachycardia including medications/substances (such as anti-cholinergic, beta-blocker withdrawal, caffeine, and alcohol) or medical conditions (such as panic attacks, pulmonary embolism, fever, hyperthyroidism, hypovolemia, anemia, and pain)...
November 29, 2017: Current Cardiology Reviews
https://www.readbyqxmd.com/read/29188054/solitary-pulmonary-capillary-hemangioma-presents-as-ground-glass-opacity-on-computed-tomography-indicating-adenocarcinoma-in-situ-atypical-adenomatous-hyperplasia-a-case-report
#20
Yanmei Zhu, Ning Qu, Lili Sun, Xiao Meng, Xiaoyan Li, Yong Zhang
Solitary pulmonary capillary hemangioma (SPCH) is a rare type of benign lung tumor, which must be distinguished from early lung cancer and precancerous lesions of the lung that manifest in a similar way upon imaging. The current study describes a case of SPCH and a review of the literature is performed. The patient was a 40-year-old Chinese woman who was referred to the Liaoning Cancer Hospital and Institute (Shenyang, China) in October, 2015 with a cough without obvious inducement. Computed tomography (CT) demonstrated pure ground glass opacity (GGO) in the right upper lung...
December 2017: Biomedical Reports
keyword
keyword
97843
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"