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https://www.readbyqxmd.com/read/28804657/a-recurrent-episode-of-dermatomyositis-associated-with-papillary-thyroid-cancer
#1
Vijay Gopal Eranki
OBJECTIVE: It is uncommon for dermatomyositis to be associated with papillary thyroid cancer. We report an unusual case of papillary thyroid cancer presenting with dermatomyositis. METHODS: The case history, imaging and laboratory data is reviewed. RESULTS: We report the case of a 62-year-old female with a prior history of dermatomyositis and breast cancer who presented with a recurrent episode of dermatomyositis. Extensive evaluation of the cause of the dermatomyositis recurrence revealed no recurrence of the breast cancer but a thyroid nodule was identified...
2017: Case Reports in Endocrinology
https://www.readbyqxmd.com/read/28801511/paraneoplastic-mucous-membrane-pemphigoid-with-ocular-and-laryngeal-involvement
#2
Silvia Lambiel, Pavel Dulguerov, Emmanuel Laffitte, Igor Leuchter
A 73-year-old woman was treated 8 years previously for synchronous breast and uterine neoplasms. She presented with a severe sore throat, odynophagia, dysphonia, dyspnoea, ocular irritation and weight loss over the last 3 months. Physical examination revealed ulcerations in the oral cavity, posterior pharyngeal wall and supraglottic larynx, nasal crusting, bilateral conjunctivitis and three cutaneous blisters. A diagnosis of anti-laminin 5 mucous membrane pemphigoid was retained, based on skin biopsy, direct immunofluorescence and immunoprecipitation...
August 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28798811/pregnancy-testing-in-patients-undergoing-radiation-therapy
#3
Shivam M Kharod, Julie Greenwalt, Camille Dessaigne, Anamaria Yeung
Radiation therapy (RT) can be lethal to a developing fetus; therefore, determining pregnancy status before RT is essential. We here sought to determine how many women treated with RT at our institution for over one year were at risk for pregnancy when starting RT. We retrospectively reviewed the medical records of all female patients 12-55 years old treated with radiation, i.e. 1 October 2012 to 31 September 2013. Patients were categorised as 'at risk' if they had a uterus and 'no risk' if they had a hysterectomy...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28798006/breast-adenoid-cystic-carcinoma-a-rare-case-report-and-review-of-the-literature
#4
Lamiae El Amarti, Hanan Raiss, Mohamed Layachi, Salif Baldé, Hamza Ettahri, Ibrahim Elghissassi, Hind Mrabti, Hassan Errihani
BACKGROUND: Primary adenoid cystic carcinoma (ACC) of the breast is a rare subtype of invasive breast cancer. It has a particular interest because of its excellent prognosis conversely to other triple-negative breast cancers that are associated with poor prognosis. The place of chemotherapy and radiotherapy remains controversial and there is no consensus on optimal management of the ACC of the breast. CASE REPORT: A 50-year-old woman, presented with a palpable right breast lump...
May 2017: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/28797032/comprehensive-geriatric-assessment-in-326-older-women-with-early-breast-cancer
#5
D O Okonji, R Sinha, I Phillips, D Fatz, A Ring
BACKGROUND: One-third of new early breast cancer diagnoses occur in women over 70 years old. However, older women are less likely to receive radical curative treatments. This study prospectively evaluated a cohort of older women using a Comprehensive Geriatric Assessment (CGA) to determine whether fitness explained the apparent under-treatment in this patient group. METHODS: In this multi-centre prospective study, patients aged ⩾70 years with Stages I-III breast cancer underwent a pretreatment baseline CGA consisting of eight assessment tools...
August 10, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28794827/preoperative-18-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-in-early-stage-breast-cancer-rates-of-distant-metastases
#6
Vincent Vinh-Hung, Hendrik Everaert, Karim Farid, Navid Djassemi, Jacqueline Baudin-Veronique, Stefanos Bougas, Yuriy Michailovich, Clarisse Joachim-Contaret, Elsa Cécilia-Joseph, Claire Verschraegen, Nam P Nguyen
AIM: To investigate rates of distant metastases (DM) detected with [18]fluorodeoxyglucose-positron emission tomography/computed tomography ((18)FDG-PET/CT) in early stage invasive breast cancer. METHODS: We searched the English language literature databases of PubMed, EMBASE, ISI Web of Knowledge, Web of Science and Google Scholar, for publications on DM detected in patients who had (18)FDG-PET/CT scans as part of the staging for early stages of breast cancer (stage I and II), prior to or immediately following surgery...
July 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/28793755/cancer-screening-rate-in-diabetic-patients-in-the-korean-population-results-from-korean-national-health-and-nutrition-examination-survey-knhanes-2007-2009
#7
Kumban Walter Chuck, Minji Hwang, Kui Son Choi, Mina Suh, Jae Kwan Jun, Boyoung Park
Purpose: To investigate the screening rate for gastric, breast, and cervical cancer in people with diabetes compared with people without diabetes. Methods: Data from the Korean National Health and Nutrition Examination survey 2007-2009 was used. Cancer-free men who were 40 years old and over and women who were 30 years old and over were included. Lifetime screening rate and regular screening rate were compared in people with and without diabetes. Results: People with diabetes received less cancer screening than people without diabetes in their lifetime (53...
August 10, 2017: Epidemiology and Health
https://www.readbyqxmd.com/read/28790868/contraception-concerns-utilization-and-counseling-needs-of-women-with-a-history-of-breast-cancer-a-qualitative-study
#8
Sheila K Mody, Danielle M Panelli, Avanthi Hulugalle, H Irene Su, Jessica R Gorman
INTRODUCTION: Reproductive-aged women who have had breast cancer face unique challenges when it comes to making decisions about contraception. Clinical guidelines indicate that patients should avoid pregnancy during cancer treatment, however the extent of contraception counseling and utilization after diagnosis has not been well studied. METHODS: We conducted three focus groups and one semi-structured interview with women between the ages of 18 and 50 years old diagnosed with breast cancer within the last 5 years...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28790265/-a-case-of-cystoid-macular-edema-secondary-to-albumin-bound-paclitaxel-therapy
#9
Tadao Ito, Katsuya Deguchi, Kazuhiro Yoshii, Mariko Kashii
A 73-year-old woman diagnosed with unresectable pancreatic cancer received weekly gemcitabine(GEM)plus albuminbound paclitaxel(nab-PTX)therapy. Four months after nab-PTX therapy was initiated, she presented with a rapidly decreasing vision in her left eye at an ophthalmology clinic. On admission, her visual acuity was decreased, and optical coherence tomography(OCT)revealed a cystoid macular edema(CME)only in her left eye. She discontinued the nab-PTX therapy immediately. Her visual acuity improved on follow-up 6 months later...
July 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28790263/-three-poor-performance-status-ps-cases-of-metastatic-breast-cancer-controlled-with-adjustment-of-dosing-interval-and-dosage-of-bevacizumab-and-paclitaxel
#10
Mitsuo Terada, Hiroshi Sugiura, Nobuyasu Yoshimoto, Sayaka Nishikawa, Yukashi Ito, Yoko Kawaguchi, Yoshiaki Ando, Yukari Hato
A standard symptomatic therapy regimen of bevacizumab(BV)plus paclitaxel(PTX)was planned for use in 3 cases of metastatic breast cancer. Due to poor patient performance status(PS)because of malignant pleural effusion and ascites, the initial standard regimen was determined to be unsuitable. However, adjustment and fine-tuning of the BV plus PTX interval and dosage were found to be effective in improving symptoms, and consequently obtained good efficacy. Adverse effects were managed with drug withdrawal and symptomatic therapy...
July 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28781789/metastatic-gastric-carcinoma-to-the-breast-a-case-report-and-review-of-the-chinese-literature
#11
Huanhuan Yan, Jun Liu, Xu Ming, Xiaoqian Zhou, Hui Jin, Xiang Li, Miao Zheng
Breast metastasis is extremely unusual in gastric cancer patients worldwide. We herein report the case of a 39-year-old female Chinese patient presenting with symptoms of inflammation in the left breast. A biopsy did not reveal any evidence of malignancy. A modified radical mastectomy was performed and the postoperative pathological examination revealed infiltration by signet ring cell gastric carcinoma. A review of the Chinese literature was performed, and a total of 16 patients with breast metastasis from gastric carcinoma have been reported from 1990 onwards...
August 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28781114/percutaneous-retrieval-of-a-port-a-cath-using-a-pigtail-catheter-combined-with-snaring-technique
#12
Mohsen Mohandes, Sergio Rojas, Verónica Quintern, Jordi Mercé, Cristina Moreno, Jordi Guarinos
We present a case of a 63-year-old woman who underwent chemotherapy for breast cancer through a port-a-cath inserted in left subclavian vein. The device was withdrawn one year later due to jugular vein thrombosis plus dysfunction of the device. A few years later a chest X-ray for scrutinizing dyspnea showed a catheter located in right heart chambers. Percutaneous retrieval via right subclavian vein was planned. Both catheter ends were impacted against heart structures and were not free to be easily captured by a snare...
July 8, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28780723/vitamin-d-receptor-gene-polymorphism-association-with-susceptibility-to-early-onset-breast-cancer-in-iranian-brca1-2-mutation-carrier-and-non-carrier-patients
#13
Ahmad Shahabi, Majid Alipour, Hamid Safiri, Parsa Tavakol, Mehdi Alizadeh, S Milad Hashemi, Mahdieh Shahabi, Mohammad Halimi
Mounting evidences support that vitamin D insufficiency or deficiency is a risk factor of breast cancer. Vitamin D receptor (VDR) is expressed in more than 36 cell types in different organs as in cancerous cells. Numerous allelic variants of VDR gene have been identified in human populations. Association of FokI (rs2228570) and BsmI (rs1544410) single nucleotide polymorphisms (SNPs) in VDR gene with the risk of breast cancer have been investigated in several studies, however, the published data are still inconsistent...
August 6, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28778029/papillotubular-carcinoma-with-an-invasive-micropapillary-carcinoma-component-of-the-breast-characterized-by-a-rapid-increase-in-size-due-to-intra-tumoral-hemorrhage-a-case-report
#14
Motonobu Watanabe, Ryota Matsuoka, Yukako Ichimura, Toshiro Takagaki, Yasushi Iitsuka
INTRODUCTION: Rapidly enlarging mammary tumors, including invasive breast tumors, are clinically rare. Invasive micropapillary carcinoma (IMPC) of the breast is known to have aggressive behavior and poor clinical course compared to invasive ductal carcinoma. CASE PRESENTATION: An 87-year-old woman presented with a rapidly enlarging tumor of the right breast over the course of 3 weeks. Ultrasonography and computed tomography of the chest revealed a giant tumor located on the right chest wall, with heterogeneous parenchymal components and several cystic lesions...
July 25, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28777295/soymilk-improves-muscle-weakness-in-young-ovariectomized-female-mice
#15
Yuriko Kitajima, Shizuka Ogawa, Shintaro Egusa, Yusuke Ono
Estrogens play a key role in an extensive range of physiological functions in various types of tissues throughout the body in females. We previously showed that estrogen insufficiency caused muscle weakness that could be rescued by estrogen administration in a young female ovariectomized (OVX) mouse model. However, long-term estrogen replacement therapy increases risks of breast cancer and cardiovascular diseases. Soymilk contains plant-based protein and isoflavones that exert estrogen-like activity. Here we examined the effects of prolonged soymilk intake on muscle and its resident stem cells, called satellite cells, in the estrogen-insufficient model...
August 4, 2017: Nutrients
https://www.readbyqxmd.com/read/28775132/shift-work-that-involves-circadian-disruption-and-breast-cancer-a-first-application-of-chronobiological-theory-and-the-consequent-challenges
#16
Lin Fritschi, J Valérie Groß, Ursula Wild, Jane S Heyworth, Deborah C Glass, Thomas C Erren
OBJECTIVES: In 2007, the International Agency for Research on Cancer classified shift work involving circadian disruption (CD) as probably carcinogenic to humans. Circadian disruption could be conceptualised as the overlap of activity, such as work, with an individual's biological night. The latter can be approximated from a worker's chronotype (or morning/evening preference). Few previous studies have taken chronotype into account when assessing CD caused by shift work. Our objective was to test the hypothesis that women working during their biological night would be at increased risk of breast cancer...
August 3, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28775079/invasive-lobular-breast-carcinoma-metastasising-to-the-rectum
#17
Nishant Cherian, Nafees Ahmad Qureshi, Callum Cairncross, Mamoon Solkar
Gastrointestinal (GI) metastasis from a primary breast carcinoma is uncommon, with the rectum being one of the least reported sites in the literature. We report a case of a 79-year-old woman who underwent treatment for an infiltrative lobular carcinoma of the right breast with nodal involvement, and 10 years later developed recurrence in the form of rectal metastasis. Spread to the GI tract is most commonly seen with lobular breast carcinomas. Any patient with a history of breast cancer presenting typically or atypically with abdominal symptoms or altered bowel habit should raise a high index of suspicion for recurrent or metastatic disease...
August 3, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28772087/selective-percutaneous-controlled-radiofrequency-thermocoagulation-of-the-gasserian-ganglion-to-control-facial-pain-due-to-medication-related-osteonecrosis-of-the-jaw
#18
Ayano Taniguchi, Keita Fukazawa, Toyoshi Hosokawa
BACKGROUND: Medication-related osteonecrosis of the jaw (MRONJ) is an important complication in patients treated with antiresorptive agents such as bisphosphonates and the receptor activator of nuclear factor κB ligand inhibitor (denosumab). Treatment of MRONJ is extremely difficult, which makes it a distressing long-term complication. OBJECTIVES: We report a case of intractable facial pain due to MRONJ that was successfully controlled with selective percutaneous controlled radiofrequency thermocoagulation of the Gasserian ganglion...
August 3, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28770167/fatal-statin-induced-rhabdomyolysis-by-possible-interaction-with-palbociclib
#19
Kellie Lynn Nelson, David Stenehjem, Meghan Driscoll, Glynn Weldon Gilcrease
A 60- to 65-year-old female on prior statin therapy was initiated on palbociclib and fulvestrant for the treatment of metastatic, hormone-receptor positive breast cancer. She subsequently developed sudden progressive muscle weakness that progressed to death within weeks. The patient noticed progressive proximal muscle weakness after two cycles of palbociclib, with no other medication changes in the interim. This rapidly progressed and resulted in death within 7 days of presentation to hospital. There has been one previous report of rhabdmyolysis with palbociclib, occurring in a patient on concomitant statin...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28768426/necrotising-fasciitis-in-a-patient-treated-with-folfiri-aflibercept-for-colorectal-cancer-a-case-report
#20
A Gonzaga-López, J Muñoz-Rodriguez, A Ruiz-Casado
Anti-angiogenics have become an important part of the treatment of several types of tumours such as ovarian, breast, lung and colorectal cancer. Necrotising fasciitis has been reported with bevacizumab but no cases have been reported with aflibercept, ramucirumab or regorafenib in patients with colorectal cancer. Necrotising fasciitis is a rare complication affecting one in 5000 bevacizumab users. We report the case of a 64-year-old man with stage IV rectosigmoid cancer under treatment with folinic acid, fluorouracil and irinotecan (FOLFIRI) and aflibercept, who developed a Fournier's gangrene...
August 3, 2017: Annals of the Royal College of Surgeons of England
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