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https://www.readbyqxmd.com/read/27918221/neutrophilic-inflammation-in-asthma-mechanisms-and-therapeutic-considerations
#1
Hun Soo Chang, Tae-Hyeong Lee, Ji Ae Jun, Ae Rin Baek, Jong-Sook Park, So My Koo, Yang-Ki Kim, Ho Sung Lee, Choon-Sik Park
Neutrophilic airway inflammation represents a pathologically distinct form of asthma and frequently appears in symptomatic adulthood asthmatics. However, clinical impacts and mechanisms of the neutrophilic inflammation have not been thoroughly evaluated up to date. Areas covered: Currently, distinct clinical manifestations, triggers, and molecular mechanisms of the neutrophilic inflammation (namely Toll-like receptor, Th1, Th17, inflammasome) are under investigation in asthma. Furthermore, possible role of the neutrophilic inflammation is being investigated in respect to the airway remodeling...
December 5, 2016: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/27910088/the-efficacy-of-greater-occipital-nerve-blockade-in-chronic-migraine-a-placebo-controlled-study
#2
H L Gul, A O Ozon, O Karadas, G Koc, L E Inan
OBJECTIVE: GON blockade with local anesthetics is an effective treatment for a group of headaches, such as cervicogenic headache, cluster headache, occipital neuralgia, migraine. Our aim was to evaluate the efficacy of greater occipital nerve (GON) blockade in patients with chronic migraine (CM) by using a control group. MATERIALS AND METHODS: We included 44 CM patients and randomly divide the patients into two groups, as group A (bupivacaine) and group B (placebo) to our study...
December 2, 2016: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/27908452/kinetics-and-mechanisms-of-nitrate-and-ammonium-formation-during-ozonation-of-dissolved-organic-nitrogen
#3
Glen Andrew de Vera, Wolfgang Gernjak, Howard Weinberg, Maria José Farré, Jurg Keller, Urs von Gunten
Dissolved organic nitrogen (DON) is an emerging concern in oxidative water treatment because it exerts oxidant demand and may form nitrogenous oxidation/disinfection by-products. In this study, we investigated the reactions of ozone with DON with a special emphasis on the formation of nitrate (NO3(-)) and ammonium (NH4(+)). In batch ozonation experiments, the formation of NO3(-) and NH4(+) was investigated for natural organic matter standards, surface water, and wastewater effluent samples. A good correlation was found between NO3(-) formation and the O3 exposure (R(2) > 0...
January 1, 2017: Water Research
https://www.readbyqxmd.com/read/27898328/fate-of-new-three-anti-influenza-drugs-and-one-prodrug-in-the-water-environment
#4
Takashi Azuma, Mao Ishida, Kanae Hisamatsu, Ayami Yunoki, Kana Otomo, Mari Kunitou, Mai Shimizu, Kaori Hosomaru, Shiori Mikata, Yoshiki Mino
We evaluated the environmental fate of new three anti-influenza drugs, favipiravir (FAV), peramivir (PER), and laninamivir (LAN), and an active prodrug of LAN, laninamivir octanoate (LANO), in comparison with four conventional drugs, oseltamivir (OS), oseltamivir carboxylate (OC), amantadine (AMN), and zanamivir (ZAN) by photodegradation, biodegradation, and sorption to river sediments. In addition, we conducted 9-month survey of urban rivers in the Yodo River basin from 2015 to 2016 (including the influenza season) to investigate the current status of occurrence of these drugs in the river environment...
November 26, 2016: Chemosphere
https://www.readbyqxmd.com/read/27889354/influence-of-ozonolysis-time-during-sugarcane-pretreatment-effects-on-the-fiber-and-enzymatic-saccharification
#5
Olavo Micali Perrone, Jessika Souza Rossi, Marcia Maria de Souza Moretti, Christiane da Costa Carreira Nunes, Sidnei Emilio Bordignon, Eleni Gomes, Roberto Da-Silva, Mauricio Boscolo
Modifications in sugarcane bagasse (SCB) from ozonolysis (O) NaOH (B) and ultrasound (U) (OBU) treatment for cellulosic ethanol production by enzymatic hydrolysis, were evaluated when increasing the exposure time of SCB to ozone. The lignin, cellulose, and hemicellulose after treatment were quantified: lignin removal and a consequent increase in cellulose content were shown using an infrared spectroscopic technique (ATR-FTIR) and chemical characterization. X-ray diffraction analysis (XRD) proved that OBU treatment does not affect the crystalline cellulose portion and electron microscopy techniques established that the fiber region most affected by the OBU treatment was the secondary cell wall, where the greatest lignin content is located...
November 15, 2016: Bioresource Technology
https://www.readbyqxmd.com/read/27889144/exploring-the-microbiota-of-the-red-brown-defect-in-smear-ripened-cheese-by-454-pyrosequencing-and-its-prevention-using-different-cleaning-systems
#6
Raffaele Guzzon, Ilaria Carafa, Kieran Tuohy, Gonzalo Cervantes, Luca Vernetti, Andrea Barmaz, Roberto Larcher, Elena Franciosi
Red-brown pigmentation can occasionally form in smeared-ripened cheese such as Fontina during the ripening process. This reaction is due to over-development of the typical microbiota present on the rind. Previous studies have demonstrated the relationship between red-brown pigmentation and the traditional utilization of wooden shelves during cheese ripening. The first part of the paper focuses on the characterisation of yeast and bacterial microbiota: plate counts and 454-pyrosequencing were performed in spoiled (n = 6) and non-spoiled cheeses (n = 6) and on the wooden shelves used during ripening...
April 2017: Food Microbiology
https://www.readbyqxmd.com/read/27886375/modulation-of-chloride-currents-in-human-lung-epithelial-cells-exposed-to-exogenous-oxidative-stress
#7
Rita Canella, Marta Martini, Roberta Borriello, Carlotta Cavicchio, Ximena M Muresan, Mascia Benedusi, Franco Cervellati, Giuseppe Valacchi
Air pollution continues to be a major public health concern affecting 9 out of 10 individuals living in urban areas worldwide. Respiratory tract is the organ most exposed to gas pollution and ozone has been shown to be one of the most noxious pollutants to which living organisms are exposed. In the present work, we have investigated the effects of 0.1 ppm of ozone on chloride currents in human lung epithelial cells (A549 line) and whether this effect could be modulated by vitamin E pre-treatment. Whole-cell patch clamp technique was applied to not excitable cells in order to obtain information about chloride currents behavior, important for epithelial lung cells homeostasis...
November 25, 2016: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/27884467/elucidating-ozonation-mechanisms-of-organic-micropollutants-based-on-dft-calculations-taking-sulfamethoxazole-as-a-case
#8
Siyu Zhang, Gang Yu, Jingwen Chen, Qing Zhao, Xuejiao Zhang, Bin Wang, Jun Huang, Shubo Deng, Yujue Wang
Ozonation is widely used in wastewater treatment plants to remove diverse organic micropollutants. As molecular structures of organic micropollutants contain multiple ozone-preferred reaction sites, and moreover intermediate products can react with ozone again, ozonation mechanism is complex. A fast increasing number of organic micropollutants and a great demand of ecological risk assessments call for an in silico method to provide insights into the ozonation mechanism of organic micropollutants. Here, an in silico model was developed to unveil ozonation mechanisms of organic micropollutants...
January 2017: Environmental Pollution
https://www.readbyqxmd.com/read/27866746/how-does-elevated-ozone-reduce-methane-emissions-from-peatlands
#9
Sylvia Toet, Viktoria Oliver, Phil Ineson, Sophie McLoughlin, Thorunn Helgason, Simon Peacock, Andrew W Stott, Jeremy Barnes, Mike Ashmore
The effects of increased tropospheric ozone (O3) pollution levels on methane (CH4) emissions from peatlands, and their underlying mechanisms, remain unclear. In this study, we exposed peatland mesocosms from a temperate wet heath dominated by the sedge Schoenus nigricans and Sphagnum papillosum to four O3 treatments in open-top chambers for 2.5years, to investigate the O3 impacts on CH4 emissions and the processes that underpin these responses. Summer CH4 emissions, were significantly reduced, by 27% over the experiment, due to summer daytime (8hday(-1)) O3 exposure to non-filtered air (NFA) plus 35ppb O3, but were not significantly affected by year-round, 24hday(-1), exposure to NFA plus 10ppb or NFA plus 25ppb O3...
November 17, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27858805/degradation-of-reactive-yellow-x-rg-by-o3-fenton-system-response-surface-approach-reaction-mechanism-and-degradation-pathway
#10
Yongjun Shen, Qihui Xu, Jun Liang, Wei Xu
O3/Fenton for the treatment of effluent containing Reactive Yellow X-RG is investigated. The response surface methodology is applied to study the main and interactive effects of the parameters. With the initial dye concentration being controlled at 300 mg L(-1), the optimized conditions for wastewater treatment are 3.68, 29.19 and 18.49 mg min(-1) for initial pH, mole ratio of [H2O2]/[Fe(2+)] and ozone dosage, respectively. The regression quadratic model well describing the degradation efficiency of O3/Fenton process is developed and validated by the analysis of variances, respectively...
November 2016: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/27855331/phenanthrene-degradation-in-soil-by-ozonation-effect-of-morphological-and-physicochemical-properties
#11
J Rodriguez, A García, T Poznyak, I Chairez
The aim of this study was to characterize the ozone reaction with phenanthrene adsorbed in two types of soils (sand and agricultural). The effect of soil physicochemical properties (texture, bulk density, particle density, porosity, elemental composition, permeability, surface area and pore volume) on the phenanthrene decomposition was evaluated. Commercial sand has a uniform morphology (spherical) with a particle size range between 0.178 and 0.150 mm in diameter, regular elemental composition SiO2, specific density of 1701...
November 14, 2016: Chemosphere
https://www.readbyqxmd.com/read/27845288/evaluation-of-the-use-of-ozone-therapy-in-treatment-of-inflammatory-processes-in-diabetes-mellitus-in-an-experiment
#12
S Karatieieva, O Yurkiv, S Semenenko, I Kozlovskaya, S Yakobchuk
Studying the effect of ozone therapy on the course of pyoinflammatory processes with diabetes mellitus in the experiment, conducted on 30 white 24-30 month rats, weight 300-450 gr with purulent-inflammatory processes, it was found out that diabetes, which was simulated by subcutaneous injection of alloxan, causes mosaic disturbances of hemostasis system in the presence of pyoinflammatory processes. Complicated changes in blood condition were also detected against the background of diabetes mellitus: chronometric hypocoagulation on the intrinsic pathway of blood coagulation in association with chronometric hypercoagulation by the external thrombinogenesis mechanism and fibrinogenesis depression against the background of hypofibrinogenaemia...
October 2016: Georgian Medical News
https://www.readbyqxmd.com/read/27837169/ccr2-regulates-inflammatory-cell-accumulation-in-the-lung-and-tissue-injury-following-ozone-exposure
#13
Mary Francis, Angela Groves, Richard Sun, Jessica A Cervelli, Hyejeong Choi, Jeffrey D Laskin, Debra L Laskin
Ozone-induced lung injury is associated with an accumulation of activated macrophages in the lung. Chemokine receptor CCR2 mediates the migration of inflammatory monocytes/macrophages to sites of tissue injury. It is also required for monocyte egress from the bone marrow. In the present studies, we analyzed the role of CCR2 in inflammatory cell trafficking to the lung in response to ozone. Treatment of mice with ozone (0.8 ppm, 3 h) resulted in increases in pro-inflammatory CCR2(+) macrophages in the lung at 24 h, as well as pro-inflammatory CD11b(+)Ly6C(Hi) and iNOS(+) macrophages at 24 h and 48 h...
November 11, 2016: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/27836172/chemical-oxidation-for-mitigation-of-uv-quenching-substances-uvqs-from-municipal-landfill-leachate-fenton-process-versus-ozonation
#14
Chanil Jung, Yang Deng, Renzun Zhao, Kevin Torrens
UV-quenching substance (UVQS), as an emerging municipal solid waste (MSW)-derived leachate contaminant, has a potential to interfere with UV disinfection when leachate is disposed of at publicly owned treatment works (POTWs). The objective of this study was to evaluate and compare two chemical oxidation processes under different operational conditions, i.e. Fenton process and ozonation, for alleviation of UV254 absorbance of a biologically pre-treated landfill leachate. Results showed that leachate UV254 absorbance was reduced due to the UVQS decomposition by hydroxyl radicals (·OH) during Fenton treatment, or by ozone (O3) and ·OH during ozonation...
January 1, 2017: Water Research
https://www.readbyqxmd.com/read/27829507/environmental-risk-assessment-of-wastewaters-from-printed-circuit-board-production-a-multibiomarker-approach-using-human-cells
#15
Marko Gerić, Goran Gajski, Višnja Oreščanin, Ana-Marija Domijan, Robert Kollar, Vera Garaj-Vrhovac
Since the production of printed circuit boards (PCBs) generates wastewater contaminated with heavy metals and organic matter, PCB factories represent potential pollution sites. The wastewater toxicologically tested in this study contained several metals and the most abundant were copper and iron. At two exposure times tested (4 and 24 h) PCB wastewater (PCBW) proved to be cytotoxic (decreased cell viability) and genotoxic (increased comet assay tail intensity and tail moment) to human blood peripheral lymphocytes in vitro, and the oxidative stress parameter (malondialdehyde concentration) was also found to be higher...
November 6, 2016: Chemosphere
https://www.readbyqxmd.com/read/27826237/the-effect-of-chronic-ozone-exposure-on-the-activation-of-endoplasmic-reticulum-stress-and-apoptosis-in-rat-hippocampus
#16
Erika Rodríguez-Martínez, Concepcion Nava-Ruiz, Elsa Escamilla-Chimal, Gabino Borgonio-Perez, Selva Rivas-Arancibia
The chronic exposure to low doses of ozone, like in environmental pollution, leads to a state of oxidative stress, which has been proposed to contribute to neurodegenerative disorders, including Alzheimer's disease (AD). It induces an increase of calcium in the endoplasmic reticulum (ER), which produces ER stress. On the other hand, different studies show that, in diseases such as Alzheimer's, there exist disturbances in protein folding where ER plays an important role. The objective of this study was to evaluate the state of chronic oxidative stress on ER stress and its relationship with apoptotic death in the hippocampus of rats exposed to low doses of ozone...
2016: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/27824188/electronic-structure-characterization-of-an-individual-single-walled-carbon-nanotube-by-in-situ-electrochemical-surface-enhanced-raman-scattering-spectroscopy
#17
Satoshi Yasuda, Shinji Hoshina, Shohei Chiashi, Shigeo Maruyama, Kei Murakoshi
We present an electronic structural analysis of an individual single-walled carbon nanotube (SWNT) by employing electrochemical surface-enhanced Raman scattering (SERS). An isolated SWNT was supported on a well-defined Au nanodimer structure, which possesses a localized surface plasmon resonance (LSPR) field at the nanogap, and highly intense SERS spectra were obtained for the SWNT at the gap region. The absolute potential of the Fermi level of the isolated SWNT in an ionic liquid was determined from the electrochemical potential dependence of the SERS intensity showing the dependence on the chirality of SWNTs...
December 7, 2016: Nanoscale
https://www.readbyqxmd.com/read/27824101/achieving-high-mobility-low-voltage-operating-organic-field-effect-transistor-nonvolatile-memory-by-an-ultraviolet-ozone-treating-ferroelectric-terpolymer
#18
Lanyi Xiang, Wei Wang, Wenfa Xie
Poly(vinylidene fluoride-trifluoroethylene) has been widely used as a dielectric of the ferroelectric organic field-effect transistor (FE-OFET) nonvolatile memory (NVM). Some critical issues, including low mobility and high operation voltage, existed in these FE-OFET NVMs, should be resolved before considering to their commercial application. In this paper, we demonstrated low-voltage operating FE-OFET NVMs based on a ferroelectric terpolymer poly(vinylidene-fluoride-trifluoroethylene-chlorotrifluoroethylene) [P(VDF-TrFE-CTFE)] owed to its low coercive field...
November 8, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27821335/enhanced-adsorption-of-diclofenac-sodium-on-the-carbon-nanotubes-polytetrafluorethylene-electrode-and-subsequent-degradation-by-electro-peroxone-treatment
#19
Qian Huang, Shubo Deng, Danna Shan, Yujue Wang, Bin Wang, Jun Huang, Gang Yu
Effective adsorption of pharmaceuticals and then degradation of them in the regeneration process are attractive for their complete removal from water or wastewater. The adsorption of diclofenac sodium (DS) on the prepared carbon nanotubes-polytetrafluorethylene (CNTs-PTFE) anode was enhanced in the presence of applied voltage. Compared with open circuit adsorption, the initial adsorption rate and adsorbed amount of DS in static adsorption experiments increased 2.1 and 1.2 times, respectively. After adsorption, the CNTs-PTFE anode was changed to cathode to in-situ degrade the adsorbed DS, and all DS was degraded after 10min using the electro-peroxone treatment...
February 15, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/27821332/transparent-wear-resistant-superhydrophobic-and-superoleophobic-poly-dimethylsiloxane-pdms-surfaces
#20
Samuel Martin, Bharat Bhushan
Superoleophobic surfaces that exhibit self-cleaning, antifouling, low-drag, and anti-smudge properties with high transparency are of interest in industrial applications including optical devices, solar panels, and self-cleaning windows. In many superoleophobic surfaces created to date, the lack of mechanical durability has been an issue. In this work, for the first time, transparent, wear-resistant, superhydrophobic and superoleophobic surfaces were developed for polydimethylsiloxane (PDMS) using a simple and scalable fabrication technique...
February 15, 2017: Journal of Colloid and Interface Science
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