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https://www.readbyqxmd.com/read/27867658/man-versus-machine-software-training-for-surgeons-an-objective-evaluation-of-human-and-computer-based-training-tools-for-cataract-surgical-performance
#1
Nizar Din, Phillip Smith, Krisztina Emeriewen, Anant Sharma, Simon Jones, James Wawrzynski, Hongying Tang, Paul Sullivan, Silvestro Caputo, George M Saleh
This study aimed to address two queries: firstly, the relationship between two cataract surgical feedback tools for training, one human and one software based, and, secondly, evaluating microscope control during phacoemulsification using the software. Videos of surgeons with varying experience were enrolled and independently scored with the validated PhacoTrack motion capture software and the Objective Structured Assessment of Cataract Surgical Skill (OSACCS) human scoring tool. Microscope centration and path length travelled were also evaluated with the PhacoTrack software...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27843291/a-new-endocapsular-open-ring-for-prevention-of-anterior-and-posterior-capsule-opacification
#2
Ioannis G Pallikaris, Nela R Stojanovic, Harilaos S Ginis
PURPOSE: The aim of this study is to demonstrate the functionality of a new design of a thick endocapsular open ring for prevention of anterior capsule opacification (ACO) and posterior capsule opacification (PCO). SETTING: The Institute of Vision and Optics, University of Crete and University Hospital of Heraklion, Crete, Greece. DESIGN: Prospective, interventional pilot study. METHODS: Fifteen patients (17 eyes) underwent cataract surgery with phacoemulsification...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27828894/rotationally-asymmetric-multifocal-intraocular-lenses-preoperative-considerations-and-postoperative-outcomes
#3
Jonathan E Moore, Richard N McNeely, Eric E Pazo, Tara C B Moore
PURPOSE OF REVIEW: The manuscript presents a review of recently published studies reporting objective and subjective outcomes and preoperative considerations of asymmetrical multifocal intraocular lenses (IOLs). RECENT FINDINGS: Current publications suggest that asymmetrical multifocal IOLs provide good, distance, intermediate and near vision for cataract and clear lens extraction patients. The contrast sensitivity achieved is similar to monofocal IOLs. Photopic phenomenon such as glare and halos has been reduced through the use of these IOLs leading to better patient satisfaction...
January 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/27818792/smile-and-wavefront-guided-lasik-out-compete-other-refractive-surgeries-in-ameliorating-the-induction-of-high-order-aberrations-in-anterior-corneal-surface
#4
Min-Jie Ye, Cai-Yuan Liu, Rong-Feng Liao, Zheng-Yu Gu, Bing-Ying Zhao, Yi Liao
Purpose. To compare the change of anterior corneal higher-order aberrations (HOAs) after laser in situ keratomileusis (LASIK), wavefront-guided LASIK with iris registration (WF-LASIK), femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK), and small incision lenticule extraction (SMILE). Methods. In a prospective study, 82 eyes underwent LASIK, 119 eyes underwent WF-LASIK, 88 eyes underwent FS-LASIK, and 170 eyes underwent SMILE surgery. HOAs were measured with Pentacam device preoperatively and 6 months after surgery...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27752608/troponin-assay-use-in-the-emergency-department-for-management-of-patients-with-potential-acute-coronary-syndrome-current-use-and-future-directions
#5
William R Fox, Deborah B Diercks
Troponins are proteins commonly found in cardiac tissue that are released during myocardial ischemia or necrosis. These troponins can be detected by assays that can then be used to guide clinical decision-making and disposition, especially if the suspected insult is related to acute coronary syndrome. Timing of troponin measurement can be important as elevations may not be detectible immediately after an insult. New assays have been designed to detect troponin con-centrations previously too low to be detected by conventional assays...
March 2016: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/27733624/stronger-net-posterior-cortical-forces-and-asymmetric-microtubule-arrays-produce-simultaneous-centration-and-rotation-of-the-pronuclear-complex-in-the-early-c-elegans-embryo
#6
Valerie C Coffman, Matthew B A McDermott, Blerta Shtylla, Adriana T Dawes
Positioning of microtubule organizing centers (MTOCs) incorporates biochemical and mechanical cues for proper alignment of the mitotic spindle and cell division site. Current experimental and theoretical studies in the early C. elegans embryo assume remarkable changes in the origin and polarity of forces acting on the MTOCs. These changes must occur over a few minutes, between initial centration and rotation of the pronuclear complex and entry into mitosis, and the models do not replicate in vivo timing of centration and rotation...
October 12, 2016: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/27722751/continuous-curvilinear-capsulorhexis-performed-with-the-verus-ophthalmic-caliper
#7
Malik Y Kahook, Robert J Cionni, Michael J Taravella, Robert E Ang, Aaron N Waite, Jonathan D Solomon, Harvey S Uy
PURPOSE: To compare size, circularity, and centration outcomes of continuous curvilinear capsulorhexis (CCC) performed with or without assistance from the VERUS ophthalmic caliper (Mile High Ophthalmics, Denver, CO). METHODS: This was a multicenter retrospective consecutive case controlled series review. RESULTS: Data from 40 consecutive cases using the VERUS device for CCC were compared to 40 consecutive cases with standard manual CCC. VERUS-assisted CCC size, circularity, and centration were closer to target compared to that of manual only procedures (P < ...
October 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27648002/regulatory-snps-alter-the-gene-expression-of-diabetic-retinopathy-associated-secretary-factors
#8
Chian-Feng Chen, Shiow-Wen Liou, Hsin-Han Wu, Chin-Hui Lin, Li-Shan Huang, Lin-Chung Woung, Ching-Yao Tsai
Objectives: Diabetic retinopathy (DR) is a common microvascular complication in both type I and type II diabetes. Several previous reports indicated the serum centration of some secretary factors were highly associated with DR. Therefore, we hypothesis regulatory SNPs (rSNPs) genotype in secretary factors may alter these gene expression and lead to DR. Methods: At first, pyrosequencing were applying to screen the SNPs which present allele frequency different in DR and DNR. Then individual genotyping was processed by Taqman assays in Taiwanese DR and DNR patients...
2016: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/27643707/tunable-substrate-wettability-by-thin-water-layer
#9
Felipe Jimenez-Angeles, Abbas Firoozabadi
In oil-water-mineral substrate systems we show that the contact angle can be tuned by an ionic structure in the water layer confined between an oil droplet and the sub strate. We perform molecular dynamics simulations of a complex oil droplet in an NaCl aqueous solution on mica surface; the oil is a mixture of n-decane and surfac tant molecules. The surfactant head contains an OH group and an aromatic ring. A thin water layer between the oil droplet and the substrate and ionic stratification regulate the wetting behavior...
September 19, 2016: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/27631415/-the-kamra%C3%A2-inlay-a%C3%A2-realistic-approach
#10
M El-Husseiny, L Daas, A Viestenz, A Langenbucher, B Seitz
BACKGROUND AND PURPOSE: The KAMRA™ inlay (AcuFocus, Irvine, California, USA) is an additional option for correcting presbyopia that has been used for many years in refractive surgery. Our objective is to report our three-month postoperative results of KAMRA™ inlay implantation in terms of near, intermediate and distance vision. PATIENTS AND METHODS: All 24 patients (average age 54.1 ± 6.0 years) were treated with the KAMRA™ inlay in the non-dominant eye (75 % in the left eye) by the same surgeon (MEH)...
September 8, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27628587/corneal-thickening-and-central-flattening-induced-by-femtosecond-laser-hyperopic-shaped-intrastromal-lenticule-implantation
#11
Leonardo Mastropasqua, Mario Nubile
PURPOSE: To investigate the feasibility of the procedure and the modifications of the corneal curvature and profile obtained with a novel technique of stromal-lentoid implantation in ex vivo human corneas. DESIGN: Experimental ex vivo study in human corneas. MATERIALS AND METHODS: Twelve stromal lentoids were produced by means of hyperopic femtosecond lenticule extraction (FLEx) with the VisuMax femtosecond laser (Carl Zeiss Meditec, Jena, Germany) with a refractive power of +8...
September 15, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27603018/understanding-and-modeling-retention-of-mammalian-cells-in-fluidized-bed-centrifuges
#12
William Kelly, Jonathan Rubin, Jennifer Scully, Hari Kamaraju, Piotr Wnukowski, Ravinder Bhatia
Within the last decade, fully disposable centrifuge technologies, fluidized-bed centrifuges (FBC), have been introduced to the biologics industry. The FBC has found a niche in cell therapy where it is used to collect, concentrate, and then wash mammalian cell product while continuously discarding centrate. The goal of this research was to determine optimum FBC conditions for recovery of live cells, and to develop a mathematical model that can assist with process scaleup. Cell losses can occur during bed formation via flow channels within the bed...
October 6, 2016: Biotechnology Progress
https://www.readbyqxmd.com/read/27554392/in-vivo-measurement-in-pigs-of-wash-in-kinetics-of-xenon-at-its-site-of-action
#13
Oliver Adolph, Gebhard Froeba
BACKGROUND: Xenon (Xe) in many respects is an ideal anaesthetic agent. Its blood/gas partition coefficient is lower than that of any other anaesthetic, enabling rapid induction of and emergence from anaesthesia. While the whole body kinetics during wash-in of inhalational anaesthesia is well known, data describing the pharmacokinetics of xenon in the cerebral compartment at the site of action are still largely missing. METHODS: In order to illuminate xenon´s cerebral pharmacokinetics, we anaesthetised five pigs and measured arterial, mixed- and sagittal sinus-venous blood, as well as end-expiratory gas concentrations of xenon by gas chromatography-mass spectrometry (GCMS) up to 30 minutes after starting the anaesthetic gas mixture...
August 23, 2016: Current Clinical Pharmacology
https://www.readbyqxmd.com/read/27552255/27-gauge-needle-assisted-technique-for-repositioning-a-dislocated-intraocular-lens
#14
Pei-Hsuan Li, Gow-Lieng Tseng, Shao-Chi Wu, Shiow-Wen Liou
BACKGROUND: Several techniques for the reposition of a posterior chamber intraocular lens (IOL) posterior dislocating into the vitreous cavity have been developed. However, most of these methods are complicated or include externalizing part of the IOL from a corneal or scleral wound. We here describe a 27-gauge needle-assisted technique for management of a dislocated posterior chamber IOL. METHODS: This is a retrospective, noncomparative, interventional case series that discusses the results of 27-gauge needle-assisted reposition of the posterior chamber IOL with transscleral sulcus fixation in 5 consecutive cases with an IOL dislocated into vitreous cavity...
September 2016: Retina
https://www.readbyqxmd.com/read/27536974/a-comparison-of-spectacles-purchased-online-and-in-uk-optometry-practice
#15
Alison J Alderson, Alison Green, David Whitaker, Andrew J Scally, David B Elliott
PURPOSE: To compare spectacles bought online with spectacles from optometry practices. METHODS: Thirty-three participants consisting of single vision spectacle wearers with either a low (N = 12, mean age 34 ± 14 years) or high prescription (N = 11, mean age 28 ± 9 years) and 10 presbyopic participants (mean age 59 ± 4 years) wearing progressive addition lenses (PALs) purchased 154 pairs of spectacles online and 154 from UK optometry practices. The spectacles were compared via participant-reported preference, acceptability, and safety; the assessment of lens, frame, and fit quality; and the accuracy of the lens prescriptions to international standard ISO 21987:2009...
October 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/27531110/-comparison-of-visual-effects-after-lasik-in-myopia-between-centered-on-the-coaxially-sighted-corneal-light-reflex-and-line-of-sight
#16
Q Cheng, J C Lian, J Zhang, W Q Yao, S S Zhang, S Ye
OBJECTIVE: To compare visual acuity, refractive outcome, high order aberrations, contrast sensitivity and subjective symptom of myopia with laser in situ keratomileusis (LASIK) centered on the coaxially sighted corneal light reflex (CSCLR group) and the conventional ablation of line of sight (LOS group). METHODS: With prospective, double-blind, randomized, controlled trial, the right eyes of patients were included and divided into two groups according to random stratified grouping...
July 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27506475/gsh-induced-controlled-release-of-levofloxacin-from-a-purpose-built-prodrug-luminescence-response-for-probing-the-drug-release-in-escherichia-coli-and-staphylococcus-aureus
#17
Suman Pal, Vadde Ramu, Nandaraj Taye, Devraj G Mogare, Amar M Yeware, Dhiman Sarkar, D Srinivasa Reddy, Samit Chattopadhyay, Amitava Das
Fluoroquinolones are third-generation broad spectrum bactericidal antibiotics and work against both Gram-positive and Gram-negative bacteria. Levofloxacin (L), a fluoroquinolone, is widely used in anti-infective chemotherapy and treatment of urinary tract infection and pneumonia. The main pathogen for urinary tract infections is Escherichia coli, and Streptococcus pneumoniae is responsible for pneumonia, predominantly a lower respiratory tract infection. Poor permeability of L leads to the use of higher dose of this drug and excess drug in the outer cellular fluid leads to central nervous system (CNS) abnormality...
September 21, 2016: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/27469426/laser-in-situ-keratomileusis-for-high-hyperopia-with-corneal-vertex-centration-and-asymmetric-offset
#18
Diego de Ortueta, Sam Arba-Mosquera
PURPOSE: To investigate refractive outcomes and induction of corneal higher order aberrations (HOA) in eyes that underwent laser-assisted in situ keratomileusis (LASIK) for high hyperopia correction using an aberration neutral profile with corneal vertex centration and asymmetric offset. METHODS: A total of 24 consecutive patients (38 eyes) who underwent LASIK by one surgeon using AMARIS 750S excimer laser and a Carriazo-Pendular microkeratome for flap creation were retrospectively analyzed...
July 23, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/27462257/tram-track-suture-technique-for-pupillary-capture-of-a-scleral-fixated-intraocular-lens
#19
Sung In Kim, Kiseok Kim
PURPOSE: To report a new technique using tram-track suture for pupillary capture of a scleral fixated posterior chamber intraocular lens (PC-IOL) to reposition the tilted IOL. METHODS: In this prospective interventional case series, we describe a tram-track suture for pupillary capture of a scleral fixated PC-IOL. A long straight needle with double-armed 10-0 polypropylene is passed behind the iris and just above the optic portion (tilted forward) of the IOL. The other straight needle with double-armed 10-0 polypropylene is passed just below the optic portion (tilted backward) of the IOL...
May 2016: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/27446606/small-incision-lenticule-extraction-for-postkeratoplasty-myopia-and-astigmatism
#20
Tamer H Massoud, Osama Ibrahim, Kitty Shehata, Moones F Abdalla
Purpose. To evaluate the visual and refractive outcomes after small incision lenticule extraction (SMILE) for treating myopia and myopic astigmatism after penetrating keratoplasty (PKP). Design. Case-series. Methods. Ten eyes of 10 patients with previous PKP and residual myopic astigmatism for whom pentacam imaging and thickness measurements were acceptable for laser vision correction. Manifest refraction (MR), uncorrected distance visual acuity (UDVA), and corrected distance visual acuity (CDVA) were obtained preoperatively and one day, one week, and one, 3, and 6 months postoperatively...
2016: Journal of Ophthalmology
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