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Peri-implant infection

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https://www.readbyqxmd.com/read/28108235/the-use-of-bacteriophages-to-biocontrol-oral-biofilms
#1
Szymon P Szafrański, Andreas Winkel, Meike Stiesch
Infections induced by oral biofilms include caries, as well as periodontal, and peri-implant disease, and may influence quality of life, systemic health, and expenditure. As bacterial biofilms are highly resistant and resilient to conventional antibacterial therapy, it has been difficult to combat these infections. An innovative alternative to the biocontrol of oral biofilms could be to use bacteriophages or phages, the viruses of bacteria, which are specific, non-toxic, self-proliferating, and can penetrate into biofilms...
January 17, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/28076651/controlled-release-of-chlorhexidine-from-a-mesoporous-silica-containing-macroporous-titanium-dental-implant-prevents-microbial-biofilm-formation
#2
K De Cremer, A Braem, E Gerits, K De Brucker, K Vandamme, J A Martens, J Michiels, J Vleugels, B P Cammue, K Thevissen
Roughened surfaces are increasingly being used for dental implant applications as the enlarged contact area improves bone cell anchorage, thereby facilitating osseointegration. However, the additional surface area also entails a higher risk for the development of biofilm associated infections, an etiologic factor for many dental ailments, including peri-implantitis. To overcome this problem, we designed a dental implant composed of a porous titanium-silica (Ti/SiO2) composite material and containing an internal reservoir that can be loaded with antimicrobial compounds...
January 11, 2017: European Cells & Materials
https://www.readbyqxmd.com/read/28065868/clinical-impact-of-positive-propionibacterium-acnes-cultures-in-orthopedic-surgery
#3
Valery Lavergne, Michel Malo, Cinzia Gaudelli, Michelle Laprade, Stéphane Leduc, Pierre Laflamme, Dominique M Rouleau
BACKGROUND: The clinical significance of a positive culture to Propionibacterium acnes in orthopedic specimens remains unclear, whether about its role as a contaminant or a pathogen, or its impact as a coinfectant. Therefore we performed a retrospective study to provide a more accurate description of the clinical impact of P.acnes in an orthopedic population aiming to determine: 1) if there is a clinical difference between P.acnes infection and contamination? 2) if there is a clinical difference between P...
January 5, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28035706/bioactive-glasses-as-delivery-systems-for-antimicrobial-agents
#4
REVIEW
Josefina Rivadeneira, Alejandro Gorustovich
Most biomaterial-associated infections are caused by opportunistic pathogens and bacteria that are regularly found within the microflora of the implant site. In addition, a biomaterial implant or device remains at risk of infection by hematogenous spread of bacteria disseminated from infections elsewhere in the body or from infected peri-implant tissue in revision surgery. The resulting infections are frequently accompanied by patient morbidity and discomfort and can lead to surgical replacement of the implant after lengthy, unsuccessful attempts to mitigate infections with antibiotic treatments...
December 30, 2016: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28000277/osseointegration-of-titanium-titanium-alloy-and-zirconia-dental-implants-current-knowledge-and-open-questions
#5
REVIEW
Dieter D Bosshardt, Vivianne Chappuis, Daniel Buser
Bone healing around dental implants follows the pattern and sequence of intramembraneous osteogenesis with formation of woven bone first of all followed later by formation of parallel-fibered and lamellar bone. Bone apposition onto the implant surface starts earlier in trabecular bone than in compact bone. While the first new bone may be found on the implant surface around 1 week after installation, bone remodeling starts at between 6 and 12 weeks and continues throughout life. Bone remodeling also involves the bone-implant interface, thus transiently exposing portions of the implant surface...
February 2017: Periodontology 2000
https://www.readbyqxmd.com/read/28000272/initial-and-long-term-crestal-bone-responses-to-modern-dental-implants
#6
REVIEW
Tomas Albrektsson, Bruno Chrcanovic, Per-Olov Östman, Lars Sennerby
Successful osseointegration is the result of a controlled foreign body reaction to dental implants. Osseointegrated implants have demonstrated excellent long-term survivability, although they may be subject to limited marginal bone loss. Marginal bone loss during the first few years after implant placement seldom represents disease, but is instead the result of an adaptive bone response to surgical trauma and implant loading. It is not uncommon for implants with early marginal bone loss to enter a long-lasting state of bone stability...
February 2017: Periodontology 2000
https://www.readbyqxmd.com/read/28000270/use-of-cone-beam-computed-tomography-in-implant-dentistry-current-concepts-indications-and-limitations-for-clinical-practice-and-research
#7
REVIEW
Michael M Bornstein, Keith Horner, Reinhilde Jacobs
Diagnostic radiology is an essential component of treatment planning in the field of implant dentistry. This narrative review will present current concepts for the use of cone beam computed tomography imaging, before and after implant placement, in daily clinical practice and research. Guidelines for the selection of three-dimensional imaging will be discussed, and limitations will be highlighted. Current concepts of radiation dose optimization, including novel imaging modalities using low-dose protocols, will be presented...
February 2017: Periodontology 2000
https://www.readbyqxmd.com/read/28000267/reliability-of-periodontal-diagnostic-tools-for-monitoring-peri-implant-health-and-disease
#8
REVIEW
Pierluigi Coli, Véronique Christiaens, Lars Sennerby, Hugo De Bruyn
The prevalence, causes and consequences of crestal bone loss at dental implants are a matter of debate. In recent years, a high prevalence of peri-implant soft-tissue inflammation, associated with peri-implant bone loss, has been reported and the need for treatments similar to those offered for natural teeth affected by periodontitis has been proposed. This suggestion is based on the assumption that periodontal indices, such as probing pocket depth and bleeding on probing, are reliable indicators of the peri-implant tissue conditions and good predictors of future bone loss...
February 2017: Periodontology 2000
https://www.readbyqxmd.com/read/27973967/10-year-patient-satisfaction-compared-between-computer-assisted-navigation-and-conventional-techniques-in-minimally-invasive-surgery-total-knee-arthroplasty
#9
Saradej Khuangsirikul, Kreangsak Lekkreusuwan, Thanainit Chotanaphuti
BACKGROUND: Both minimally invasive surgery (MIS) and computer-assisted surgery (CAS) in total knee arthroplasty have been scientifically linked with surgical benefits. However, the long-term results of these techniques are still controversial. Most surgeons assessed the surgical outcomes with regard to knee alignment and range of motion, but these factors may not reflect subjective variables, namely patient satisfaction. PURPOSE: To compare satisfaction and functional outcomes between two technical procedures in MIS total knee arthroplasty, namely computer-assisted MIS and conventional MIS procedure, operated on a sample group of patients after 10 years...
December 2016: Comput Assist Surg (Abingdon)
https://www.readbyqxmd.com/read/27935124/erythritol-chlorhexidine-combination-reduces-microbial-biofilm-and-prevents-its-formation-on-titanium-surfaces-in-vitro
#10
Lorenzo Drago, Monica Bortolin, Silvio Taschieri, Elena De Vecchi, Serse Agrappi, Massimo Del Fabbro, Luca Francetti, Roberto Mattina
BACKGROUND: The purpose of this in vitro study was to evaluate the antibiofilm activity of a novel air-polishing powder consisting of erythritol and chlorhexidine, assessing its ability to reduce previously grown microbial biofilm and to prevent biofilm formation on titanium surfaces. METHODS: Clinical strains of Staphylococcus aureus, Pseudomonas aeruginosa, Bacteroides fragilis and Candida albicans isolated from peri-implantitis lesions were used. Biofilm was grown on sandblasted titanium discs and treated with erythritol/chlorhexidine...
December 9, 2016: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/27924602/genome-wide-analysis-of-periodontal-and-peri-implant-cells-and-tissues
#11
Moritz Kebschull, Claudia Hülsmann, Per Hoffmann, Panos N Papapanou
Omics analyses, including the systematic cataloging of messenger RNA and microRNA sequences or DNA methylation patterns in a cell population, organ or tissue sample, are powerful means of generating comprehensive genome-level data sets on complex diseases. We have systematically assessed the transcriptome, miRNome and methylome of gingival tissues from subjects with different diagnostic entities of periodontal disease, and studied the transcriptome of primary cells ex vivo, or in vitro after infection with periodontal pathogens...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27910125/bioprosthetic-tricuspid-valve-replacement-for-tricuspid-valve-endocarditis-secondary-to-infected-endocardial-pacemaker-leads
#12
Zhiwei Xu, Qiuxia Shi, Ju Mei, Yan Tan
BACKGROUND: The purpose of this study was to present outcomes of bioprosthetic tricuspid valve replacement (TVR) in patients with tricuspid valve infective endocarditis (TVIE). METHODS: From October 2001 to December 2015, 26 patients underwent a bioprosthetic TVR due to severe TVIE after endocardial pacemaker implantation. RESULTS: Staphylococcus species and Streptococcus species were the predominant microorganisms. Early 30-day hospital mortality was 0 (0%)...
January 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/27890003/biofilm-mediated-antibiotic-resistant-oral-bacterial-infections-mechanism-and-combat-strategies
#13
Indu Lata Kanwar, Abhishek Kumar Sah, Preeti K Suresh
Oral diseases like dental caries and periodontal disease are directly associated with the capability of bacteria to form biofilm. Periodontal diseases have been associated to anaerobic Gram-negative bacteria forming a subgingival plaque (Porphyromonas gingivalis, Actinobacillus, Prevotella and Fusobacterium). Biofilm is a complex bacterial community that is highly resistant to antibiotics and human immunity. Biofilm communities are the causative agents of biological developments such as dental caries, periodontitis, and peri-implantitis, and causing periodontal tissue breakdown...
24, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27882310/minimal-invasive-horizontal-ridge-augmentation-using-subperiosteal-tunneling-technique
#14
Hyun-Suk Kim, Young-Kyun Kim, Pil-Young Yun
BACKGROUND: The goal of this study was to retrospectively evaluate the prognosis of minimal invasive horizontal ridge augmentation (MIHRA) technique using small incision and subperiosteal tunneling technique. METHODS: This study targeted 25 partially edentulous patients (10 males and 15 females, mean age 48.8 ± 19.7 years) who needed bone graft for installation of the implants due to alveolar bone deficiency. The patients took the radiographic exam, panoramic and periapical view at first visit, and had implant fixture installation surgery...
December 2016: Maxillofacial Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27833731/bone-cells-dynamics-during-peri-implantitis-a-theoretical-analysis
#15
REVIEW
Maria Helena Fernandes, Pedro de Sousa Gomes
OBJECTIVES: The present manuscript aims a detailed characterization of the bone cells dynamics during physiological bone remodelling and, subsequently, to address the cellular and molecular mechanisms that play a fundamental role in the immune-inflammatory-induced uncoupled bone remodelling observed in peri-implantitis. RESULTS: An intimate relationship between the immune system and bone is acknowledged to be determinant for bone tissue remodelling and integrity...
July 2016: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/27793325/occlusal-trauma-and-mucositis-or-peri-implantitis
#16
Euloir Passanezi, Adriana Campos Passanezi Sant'Ana, Carla Andreotti Damante
BACKGROUND AND OVERVIEW: The aim of this study was to describe the effects of bruxism in peri-implant bone loss 6 years after the placement of a successful implant-supported prosthesis, to describe its treatment, and to propose a differential diagnosis of the lesion. CASE DESCRIPTION: A 62-year-old, nonsmoking, systemically healthy partially edentulous woman received 2 osseointegrated implants in the mandibular left region, which supported a 3-element fixed prosthesis...
October 25, 2016: Journal of the American Dental Association
https://www.readbyqxmd.com/read/27786620/a-novel-rat-model-of-polymicrobial-peri-implantitis-a-preliminary-study
#17
Theofilos Koutouzis, Christie Eastman, Sasanka Chukkapalli, Hannu Larjava, Lakshmyya Kesavalu
BACKGROUND: Peri-implantitis is a complex polymicrobial biofilm-induced inflammatory osteolytic gingival infection that results in orofacial implant failures. There are no preclinical in vivo studies in implant dentistry that have investigated the inflammatory response to known microbial biofilms observed in humans. The aim is to develop a novel peri-implant rat model using an established model of polymicrobial periodontitis. METHODS: Wistar rats were used for the study of experimental peri-implantitis...
October 27, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27770768/phage-therapy-a-new-horizon-in-the-antibacterial-treatment-of-oral-pathogens
#18
Mor Shlezinger, Yael Houri-Haddad, Shunit Coppenhagen-Glazer, Grégory Resch, Yok-Ai Que, Shaul Beyth, Elisheva Dorfman, Ronen Hazan, Nurit Beyth
Dental diseases are perhaps the most prevalent infection-related diseases in humans. Biofilm is involved in almost every infectious disease compromising oral health, notably caries, periodontal disease, gingivitis, endodontic infections and peri-implantitis. Current therapies of biofilm-derived oral infections lack sensitivity; they are not species-specific and kill pathogenic species as well as commensal species, which are protective against the formation of pathogenic biofilms. Moreover, antibiotics have a limited effect on biofilm and are almost unused in oral diseases...
September 30, 2016: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/27750384/anti-biofilm-properties-of-bioactive-glasses-embedding-organic-active-compounds
#19
REVIEW
M E Galarraga-Vinueza, J Mesquita-Guimarães, R S Magini, J C M Souza, M C Fredel, A R Boccaccini
Bioactive glasses (BGs) are promising materials for bone repair due to their desirable properties such as osteoconductivity, biodegradability, angiogenic potential, and antibacterial activity. Ionic dissolution products from bioactive glasses increase the medium pH inhibiting surrounding bacteria proliferation. The activity of BGs against biofilm formation has been enhanced by incorporating organic antibacterial compounds. The aim of this review was to summarize evidence in literature which assesses the efficacy of antibacterial and anti-biofilm compounds embedded in bioactive glasses to prevent peri-implant infection during bone healing...
February 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/27747699/rehabilitation-of-a-complex-midfacial-defect-by-means-of-a-zygoma-implant-supported-prosthesis-and-nasal-epithesis-a-novel-technique
#20
Lorenzo Trevisiol, Pasquale Procacci, Antonio D'Agostino, Francesca Ferrari, Daniele De Santis, Pier Francesco Nocini
PURPOSE: Several authors have described zygoma implants as a reliable surgical option to rehabilitate severe maxillary defects in case of extreme atrophy or oncological resections. The aim of this study is to report a new technical approach to the rehabilitation of a complex oronasal defect by means of a zygoma-implant-supported full-arch dental prosthesis combined with a nasal epithesis. PATIENTS AND METHODS: The patient presented with a subtotal bilateral maxillectomy and total rhinectomy defect because of a squamous cell carcinoma of the nose...
December 2016: International Journal of Implant Dentistry
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