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Peri-implant infection

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https://www.readbyqxmd.com/read/27890003/biofilm-mediated-antibiotic-resistant-oral-bacterial
#1
Indu Lata Kanwar, Abhishek Kumar Sah, Preeti K Suresh
Oral diseases like dental caries and periodontal disease are directly associated with the capability of bacteria to form biofilm. Periodontal diseases have been associated to anaerobic Gram-negative bacteria forming a subgingival plaque (Porphyromonas gingivalis, Actinobacillus, Prevotella and Fusobacterium). Biofilm is a complex bacterial community that is highly resistant to antibiotics and human immunity. Biofilm communities are the causative agents of biological developments such as dental caries, periodontitis, and peri-implantitis, and causing periodontal tissue breakdown...
November 24, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27882310/minimal-invasive-horizontal-ridge-augmentation-using-subperiosteal-tunneling-technique
#2
Hyun-Suk Kim, Young-Kyun Kim, Pil-Young Yun
BACKGROUND: The goal of this study was to retrospectively evaluate the prognosis of minimal invasive horizontal ridge augmentation (MIHRA) technique using small incision and subperiosteal tunneling technique. METHODS: This study targeted 25 partially edentulous patients (10 males and 15 females, mean age 48.8 ± 19.7 years) who needed bone graft for installation of the implants due to alveolar bone deficiency. The patients took the radiographic exam, panoramic and periapical view at first visit, and had implant fixture installation surgery...
December 2016: Maxillofacial Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27833731/bone-cells-dynamics-during-peri-implantitis-a-theoretical-analysis
#3
REVIEW
Maria Helena Fernandes, Pedro de Sousa Gomes
OBJECTIVES: The present manuscript aims a detailed characterization of the bone cells dynamics during physiological bone remodelling and, subsequently, to address the cellular and molecular mechanisms that play a fundamental role in the immune-inflammatory-induced uncoupled bone remodelling observed in peri-implantitis. RESULTS: An intimate relationship between the immune system and bone is acknowledged to be determinant for bone tissue remodelling and integrity...
July 2016: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/27793325/occlusal-trauma-and-mucositis-or-peri-implantitis
#4
Euloir Passanezi, Adriana Campos Passanezi Sant'Ana, Carla Andreotti Damante
BACKGROUND AND OVERVIEW: The aim of this study was to describe the effects of bruxism in peri-implant bone loss 6 years after the placement of a successful implant-supported prosthesis, to describe its treatment, and to propose a differential diagnosis of the lesion. CASE DESCRIPTION: A 62-year-old, nonsmoking, systemically healthy partially edentulous woman received 2 osseointegrated implants in the mandibular left region, which supported a 3-element fixed prosthesis...
October 25, 2016: Journal of the American Dental Association
https://www.readbyqxmd.com/read/27786620/a-novel-rat-model-of-polymicrobial-peri-implantitis-a-preliminary-study
#5
Theofilos Koutouzis, Christie Eastman, Sasanka Chukkapalli, Hannu Larjava, Lakshmyya Kesavalu
BACKGROUND: Peri-implantitis is a complex polymicrobial biofilm-induced inflammatory osteolytic gingival infection that results in orofacial implant failures. There are no preclinical in vivo studies in implant dentistry that have investigated the inflammatory response to known microbial biofilms observed in humans. The aim is to develop a novel peri-implant rat model using an established model of polymicrobial periodontitis. METHODS: Wistar rats were used for the study of experimental peri-implantitis...
October 27, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27770768/phage-therapy-a-new-horizon-in-the-antibacterial-treatment-of-oral-pathogens
#6
Mor Shlezinger, Yael Houri-Haddad, Shunit Coppenhagen-Glazer, Grégory Resch, Yok-Ai Que, Shaul Beyth, Elisheva Dorfman, Ronen Hazan, Nurit Beyth
Dental diseases are perhaps the most prevalent infection-related diseases in humans. Biofilm is involved in almost every infectious disease compromising oral health, notably caries, periodontal disease, gingivitis, endodontic infections and peri-implantitis. Current therapies of biofilm-derived oral infections lack sensitivity; they are not species-specific and kill pathogenic species as well as commensal species, which are protective against the formation of pathogenic biofilms. Moreover, antibiotics have a limited effect on biofilm and are almost unused in oral diseases...
September 30, 2016: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/27750384/anti-biofilm-properties-of-bioactive-glasses-embedding-organic-active-compounds
#7
M E Galarraga-Vinueza, J Mesquita-Guimarães, R S Magini, J C M Souza, M C Fredel, A R Boccaccini
Bioactive glasses (BGs) are promising materials for bone repair due to their desirable properties such as osteoconductivity, biodegradability, angiogenic potential, and antibacterial activity. Ionic dissolution products from bioactive glasses increase the medium pH reducing surrounding bacteria proliferation. The activity of BGs against biofilm formation has been enhanced by incorporating organic antibacterial compounds. The aim of this review was to summarize evidence in literature which assesses the efficacy of antibacterial and anti-biofilm compounds embedded in bioactive glasses to prevent peri-implant infection during bone healing...
October 17, 2016: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/27747699/rehabilitation-of-a-complex-midfacial-defect-by-means-of-a-zygoma-implant-supported-prosthesis-and-nasal-epithesis-a-novel-technique
#8
Lorenzo Trevisiol, Pasquale Procacci, Antonio D'Agostino, Francesca Ferrari, Daniele De Santis, Pier Francesco Nocini
PURPOSE: Several authors have described zygoma implants as a reliable surgical option to rehabilitate severe maxillary defects in case of extreme atrophy or oncological resections. The aim of this study is to report a new technical approach to the rehabilitation of a complex oronasal defect by means of a zygoma-implant-supported full-arch dental prosthesis combined with a nasal epithesis. PATIENTS AND METHODS: The patient presented with a subtotal bilateral maxillectomy and total rhinectomy defect because of a squamous cell carcinoma of the nose...
December 2016: Int J Implant Dent
https://www.readbyqxmd.com/read/27707853/developing-a-clinically-representative-model-of-periprosthetic-joint-infection
#9
Alberto V Carli, F Patrick Ross, Samrath J Bhimani, Scott R Nodzo, Mathias P G Bostrom
➤The poor treatment outcomes for periprosthetic joint infection (PJI) reflect the limited understanding that currently exists regarding the pathogenesis of this devastating clinical problem.➤Current animal models of PJI are limited in their translational nature primarily because of their inability to recreate the periprosthetic environment.➤A greater mechanistic understanding of the musculoskeletal and immune systems of small animals, such as mice and rats, provides a more robust platform for modeling and examining the pathogenesis of PJI...
October 5, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27704604/early-implant-associated-osteomyelitis-results-in-a-peri-implanted-bacterial-reservoir
#10
Louise Kruse Jensen, Janne Koch, Bent Aalbaek, Arshnee Moodley, Thomas Bjarnsholt, Kasper Nørskov Kragh, Andreas Petersen, Henrik Elvang Jensen
Implant-associated osteomyelitis (IAO) is a common complication in orthopedic surgery. The aim of this study was to elucidate how deep IAO can go into the peri-implanted bone tissue within a week. The study was performed in a porcine model of IAO. A small steel implant and either 10(4) CFU/kg body weight of Staphylococcus aureus or saline was inserted into the right tibial bone of 12 pigs. The animals were consecutively killed on day 2, 4 and 6 following implantation. Bone tissue around the implant was histologically evaluated...
October 5, 2016: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/27700696/enterococcus-faecalis-and-dental-implants
#11
Dennis Flanagan
E. faecalis appears in many tooth root infections and is not eliminated by root canal therapy. It can reside in tooth root canals and the surrounding bone. This species may vegetate in bone after extraction of an infected tooth and colonize a dental implant after placement in the healed site. A colonization may cause fixture loss or marginal bone loss. These colonizations are generally multi-bacterial and pathogenic properties can be shared via plasmids. However, E. faecalis is not detectable with some culture techniques and thus can be missed...
October 4, 2016: Journal of Oral Implantology
https://www.readbyqxmd.com/read/27697397/implants-in-free-fibula-flap-supporting-dental-rehabilitation-implant-and-peri-implant-related-outcomes-of-a-randomized-clinical-trial
#12
Vinay V Kumar, Supriya Ebenezer, Peer W Kämmerer, P C Jacob, Moni A Kuriakose, Naveen Hedne, Wilfried Wagner, Bilal Al-Nawas
OBJECTIVES: The objective of this study was to assess the difference in success rates of implants when using two or four implant-supported-overdentures following segmental mandibular reconstruction with fibula free flap. METHODS AND DESIGNS: This prospective, parallel designed, randomized clinical study was conducted with 1:1 ratio. At baseline, all participants already had segmental reconstruction of mandible with free fibula flap. The participants were randomized into two groups: Group-I received implant-supported-overdentures on two tissue-level implants and Group-II received implant-supported-overdentures on four tissue-level implants...
November 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/27632667/-the-role-of-a-modular-universal-tumour-and-revision-system-mutars%C3%A2-in-lower-limb-endoprosthetic-revision-surgery-outcome-analysis-of-25-patients
#13
J Schmolders, S Koob, P Schepers, S Gravius, D C Wirtz, C Burger, P H Pennekamp, A C Strauss
Introduction/Background: With extended life expectancy, the number of primary joint arthroplasties has also increased. Revision surgery is also more often necessary, due to aseptic or septic loosening of the prosthesis or periprosthetic fracture. Large bone defects often occur in these patients and several non-modular, conventional implants are available to handle this difficult situation. Custom made implants offer an individually designed and defect-adapted shape with perfect covering of the lesion, but may delay the operation...
September 15, 2016: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/27596293/effects-of-low-frequency-ultrasound-treatment-of-titanium-surface-roughness-on-osteoblast-phenotype-and-maturation
#14
Janina Sedlaczek, Christoph H Lohmann, Ethan M Lotz, Sharon L Hyzy, Barbara D Boyan, Zvi Schwartz
OBJECTIVE: Low-frequency ultrasound is widely used in the treatment of chronically infected wounds. To investigate its feasibility as a method for in situ restoration of metal implant surfaces in cases of peri-implantitis, we evaluated how low-frequency ultrasound affected surface properties of and response of human osteoblast-like MG63 cells to titanium (Ti). MATERIAL AND METHODS: Three Ti surfaces [hydrophobic/smooth (pretreatment, PT); hydrophobic/rough (sandblasted/acid-etched, SLA); and hydrophilic/rough (SLA processed and stored hydrophilicity, mSLA)] were subjected to 25 kHz ultrasound for 10 min/cm(2) ...
September 5, 2016: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/27544827/venous-cutdown-versus-the-seldinger-technique-for-placement-of-totally-implantable-venous-access-ports
#15
REVIEW
Charlie C-T Hsu, Gigi N C Kwan, Hannah Evans-Barns, John A Rophael, Mieke L van Driel
BACKGROUND: Totally implantable venous access ports (TIVAPs) provide patients with a safe and permanent venous access, for instance in the administration of chemotherapy for oncology patients. There are several methods for TIVAP placement, and the optimal evidence-based method is unclear. OBJECTIVES: To compare the efficacy and safety of three commonly used techniques for implanting TIVAPs: the venous cutdown technique, the Seldinger technique, and the modified Seldinger technique...
August 21, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27525370/feasibility-and-safety-of-reveal-linq-insertion-in-a-sterile-procedure-room-versus-electrophysiology-laboratory
#16
Geoffrey R Wong, Dennis H Lau, Melissa E Middeldorp, Judith A Harrington, Simon Stolcman, Lauren Wilson, Darragh J Twomey, Sharath Kumar, Dian A Munawar, Kashif B Khokhar, Rajiv Mahajan, Prashanthan Sanders
BACKGROUND: Insertable cardiac monitors (ICMs) are increasingly utilized for diagnosis of unexplained syncope and arrhythmia monitoring. The Reveal LINQ is a novel miniaturized ICM with improved algorithms. The feasibility and safety of insertion outside the traditional electrophysiology laboratory is unknown. Here we compare outcomes of Reveal LINQ insertion in different environments. METHODS: We report on a prospective, single-centre, non-randomized, observational experience of consecutive Reveal LINQ implantation in the electrophysiology laboratory or a procedure room between October 2013 and October 2015...
November 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27498713/a-novel-treatment-decision-tree-and-literature-review-of-retrograde-peri-implantitis
#17
Nima D Sarmast, Howard H Wang, Nikolaos K Soldatos, Nikola Angelov, Samuel Dorn, Raymond Yukna, Vincent J Iacono
BACKGROUND: Although retrograde peri-implantitis (RPI) is not a common sequela of dental implant surgery, its prevalence has been reported in the literature to be 0.26%. Incidence of RPI is reported to increase to 7.8% when teeth adjacent to the implant site have a previous history of root canal therapy, and it is correlated with distance between implant and adjacent tooth and/or with time from endodontic treatment of adjacent tooth to implant placement. Minimum 2 mm space between implant and adjacent tooth is needed to decrease incidence of apical RPI, with minimum 4 weeks between completion of endodontic treatment and actual implant placement...
December 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27469422/correlation-between-pre-operative-buccal-bone-thickness-and-soft-tissue-changes-around-immediately-placed-and-restored-implants-in-the-maxillary-anterior-region-a-2-year-prospective-study
#18
Himanshu Arora, Saso Ivanovski
OBJECTIVES: This study evaluated the correlation between pre-operative buccal cortical bone thickness and peri-implant tissue response following immediate placement and restoration of implants in the maxillary aesthetic zone. MATERIAL AND METHODS: Eighteen patients (3 males, 15 females) with an age range of 19-57 years requiring the replacement of a single maxillary anterior tooth were included in this prospective study. Patients were selected on the basis of defined criteria: intact socket walls, absence of any acute infection in the sockets, absence of any gingival marginal pathology and attainment of a high primary stability (≥30 Ncm) at implant placement...
July 29, 2016: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/27457788/antibacterial-effect-of-copper-bearing-titanium-alloy-ti-cu-against-streptococcus-mutans-and-porphyromonas-gingivalis
#19
Rui Liu, Kaveh Memarzadeh, Bei Chang, Yumei Zhang, Zheng Ma, Robert P Allaker, Ling Ren, Ke Yang
Formation of bacterial biofilms on dental implant material surfaces (titanium) may lead to the development of peri-implant diseases influencing the long term success of dental implants. In this study, a novel Cu-bearing titanium alloy (Ti-Cu) was designed and fabricated in order to efficiently kill bacteria and discourage formation of biofilms, and then inhibit bacterial infection and prevent implant failure, in comparison with pure Ti. Results from biofilm based gene expression studies, biofilm growth observation, bacterial viability measurements and morphological examination of bacteria, revealed antimicrobial/antibiofilm activities of Ti-Cu alloy against the oral specific bacterial species, Streptococcus mutans and Porphyromonas gingivalis...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27454339/effects-of-surface-conditions-of-titanium-dental-implants-on-bacterial-adhesion
#20
Chun-Ju Chen, Shinn-Jyh Ding, Chun-Cheng Chen
OBJECTIVE: The study is to evaluate the effect of surface roughness of titanium implants on bacterial adhesion and then to investigate the efficacy of the three cleaning treatments for bacterial removal in titanium surfaces. BACKGROUND DATA: Although surface debridement is the basic element for treatment of peri-implantitis to reduce bacterial adhesion, adjunctive therapies such as antiseptics and laser debridement have been proposed to improve the nonsurgical treatment options of the peri-implant infection...
September 2016: Photomedicine and Laser Surgery
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