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Peri-implant infection

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https://www.readbyqxmd.com/read/28791884/added-value-of-18f-fdg-pet-ct-in-diagnosing-infected-hip-prosthesis
#1
Robert M Kwee, Wouter Am Broos, Boudewijn Brans, Geert Him Walenkamp, Jan Geurts, René E Weijers
Background The diagnosis of infected hip prosthesis is frequently not straightforward yet very important as it changes treatment. Purpose To retrospectively investigate the added value of 18F-FDG PET/CT to conventional tests including radiography, erythrocyte sedimentation rate (ESR)/C-reactive protein (CRP) testing, and joint aspiration, in diagnosing infected hip prosthesis. Material and Methods Seventy-eight hip prostheses of 78 patients (55% men; mean age = 66.5 years; age range = 30-85 years) with non-specific clinical presentation, i...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28765610/high-mobility-group-box-1-protein-level-as-a-novel-biomarker-for-the-development-of-peri-implant-disease
#2
Jinpan Liu, Ronghui Li, Tongjun Liu, Xiaohui Rausch-Fan, Mingguo Wang
Peri-implant disease is a chronic inflammation of the soft and hard tissues around a dental implant, resulting from bacterial infection. Recent evidence indicates that some pro-inflammatory cytokines and chemokines released by immunocytes are substantially responsible for the progress and consequence of inflammation. High mobility group box 1 (HMGB1) is released into the extracellular matrix and acts as a key pro-inflammatory factor during injury, necrosis and inflammation. A higher concentration of HMGB1 has been found in gingival crevicular fluid from inflammatory gingival tissue than from healthy sites...
August 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28757930/efficacy-of-a-new-coating-of-implant-abutment-connections-in-reducing-bacterial-loading-an-in-vitro-study
#3
D Lauritano, C A Bignozzi, D Pazzi, F Cura, F Carinci
BACKGROUND: Titanium is the gold standard for dental implants, since it has demonstrated excellent biocompatibility and osseointegration properties. The rate of osseointegration is however affected by the surface morphology and peri-implant infections may affect fixture and the long-term osseointegration outcome. Thus chemical composition of a coating at the implant-abutment junction (IAJ) surface is expected to play a key role in preventing bacterial infection. PURPOSE: In the present study a new antimicrobial polysiloxane coating functionalized with chlorexidine digluconate (PXT) has been tested in an in vitro model...
January 2017: Oral & Implantology
https://www.readbyqxmd.com/read/28730548/orthopedic-infections-caused-by-obligatory-anaerobic-gram-negative-rods-report-of-two-cases
#4
Marta Kierzkowska, Piotr Pedzisz, Ireneusz Babiak, Jakub Janowicz, Mateusz Kulig, Anna Majewska, Anna Sawicka-Grzelak, Grazyna Mlynarczyk
Anaerobic bone and joint infections are uncommon, although the number of anaerobic infections is presumably underestimated because of difficulties with isolation and identification of obligate anaerobes. This study describes two cases of complicated Bacteroides fragilis peri-implant infection of the lumbar spine, infection of the hip and osteomyelitis. Bacteria were identified with the use of a mass spectrometer, VITEK MS system. Drug susceptibility was performed with the use of E-test. The EUCAST breakpoints were used for interpretation with B...
July 20, 2017: Medical Microbiology and Immunology
https://www.readbyqxmd.com/read/28726761/a-cell-adhesive-plasma-polymerized-allylamine-coating-reduces-the-in-vivo-inflammatory-response-induced-by-ti6al4v-modified-with-plasma-immersion-ion-implantation-of-copper
#5
Uwe Walschus, Andreas Hoene, Maciej Patrzyk, Silke Lucke, Birgit Finke, Martin Polak, Gerold Lukowski, Rainer Bader, Carmen Zietz, Andreas Podbielski, J Barbara Nebe, Michael Schlosser
Copper (Cu) could be suitable to create anti-infective implants based on Titanium (Ti), for example by incorporating Cu into the implant surface using plasma immersion ion implantation (Cu-PIII). The cytotoxicity of Cu might be circumvented by an additional cell-adhesive plasma polymerized allylamine film (PPAAm). Thus, this study aimed to examine in vivo local inflammatory reactions for Ti6Al4V implants treated with Cu-PIII (Ti-Cu), alone or with an additional PPAAm film (Ti-Cu-PPAAm), compared to untreated implants (Ti)...
July 20, 2017: Journal of Functional Biomaterials
https://www.readbyqxmd.com/read/28702784/cementless-modular-distally-fixed-stem-in-hip-revision-arthroplasty-a-single-center-study-of-132-consecutive-hips
#6
Ali Hashem, Ammar Al-Azzawi, Hasan Riyadh, Sebastian Mukka, Arkan Sayed-Noor
PURPOSE: The use of cementless, modular, distally fixed stem in hip revision arthroplasty has increased during the last decades. We aimed to analyze the early and late postoperative complications, re-operation rate, and survival rate of the MP stem operated at our county hospital with relatively limited caseload. METHODS: In this retrospective study, we included 132 hips operated with MP stem between January 2007-2014. An independent observer reviewed patients' medical records in July 2015 (18-102 months postoperatively, median 52...
July 12, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28696671/simultaneous-delivery-of-multiple-antibacterial-agents-from-additively-manufactured-porous-biomaterials-to-fully-eradicate-planktonic-and-adherent-staphylococcus-aureus
#7
S Bakhshandeh, Z Gorgin Karaji, K Lietaert, A C Fluit, C H E Boel, H C Vogely, T Vermonden, W E Hennink, H Weinans, A A Zadpoor, S Amin Yavari
Implant-associated infections are notoriously difficult to treat and may even result in amputation and death. The first few days after surgery are the most critical time to prevent those infections, preferably through full eradication of the micro-organisms entering the body perioperatively. That is particularly important for patients with a compromised immune system such as orthopedic oncology patients, as they are at higher risk for infection and complications. Full eradication of bacteria is, especially in a biofilm, extremely challenging due to the toxicity barrier that prevents delivery of high doses of antibacterial agents...
August 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28688362/ph-dependent-silver-nanoparticles-releasing-titanium-implant-a-novel-therapeutic-approach-to-control-peri-implant-infection
#8
Yiwen Dong, Hui Ye, Yi Liu, Lihua Xu, Zuosu Wu, Xiaohui Hu, Jianfeng Ma, Janak L Pathak, Jinsong Liu, Gang Wu
Peri-implant infection control is crucial for implant fixation and durability. Antimicrobial administration approaches to control peri-implant infection are far from satisfactory. During bacterial infection, pH level around the peri-implant surface decreases as low as pH 5.5. This change of pH can be used as a switch to control antimicrobial drug release from the implant surface. Silver nanoparticles (AgNPs) have broad-spectrum antimicrobial properties. In this study, we aimed to design a pH-dependent AgNPs releasing titania nanotube arrays (TNT) implant for peri-implant infection control...
June 23, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28684070/the-influence-of-different-abutment-materials-on-tissue-regeneration-after-surgical-treatment-of-peri-implantitis-a-randomized-controlled-preclinical-study
#9
Tobias Moest, Jan Wrede, Christian Martin Schmitt, Melanie Stamp, Friedrich Wilhelm Neukam, Karl Andreas Schlegel
OBJECTIVES: This study aimed to assess the impact of different abutment materials on peri-implant tissue regeneration after surgical treatment of peri-implantitis in a large animal model. MATERIAL AND METHODS: Titanium implants (n = 51) were inserted in the upper and lower jaw of eight beagle dogs and a peri-implant infection was induced. After two months the peri-implant infection was surgically treated and abutments with different surfaces (Ti-2: n = 14; CoCrMb: n = 13; Ag-modified Ti-4: n = 14; Ti-4 control: n = 10) were applied...
June 3, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28664712/comparative-study-on-usefulness-of-gentamycin-containing-collagen-implants-in-the-treatment-of-patients-with-osteitis-and-osteomyelitis-of-the-craniofacial-skeleton
#10
COMPARATIVE STUDY
Paweł J Zawadzki, Konrad Perkowski, Michał Kotlarski, Anna Pietruczuk-Padzik, Lidia Chomicz
<b>Introduction and objective.</b> A reduction in incidences of peri-surgical complications due to infections is achieved by antibiotic prophylaxis The objective of the study was to assess the usefulness of gentamycin-containing collagen implants (GCCI) in the treatment of patients with osteitis and osteomyelitis of the craniofacial skeleton. <b>Materials and method.</b> The retrospective study included 103 patients with osteitis and osteomyelitis. 54 patients were treated intra-operatively with GCCI (Garamycin, EusaPharma, Europe)...
May 11, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/28657565/robotic-arm-assisted-partial-knee-arthroplasty-a-single-centre-experience
#11
Andrea Marcovigi, Francesco Zambianchi, Dario Sandoni, Elisa Rivi, Fabio Catani
BACKGROUND AND AIM OF THE WORK: UKA has proven to be an effective surgical procedure, but its survivorship is still negatively affected by inaccuracy in component component positioning, implant and limb alignment. Robotic surgery has been introduced in order to minimize such technical errors. The aim of the present paper was to evaluate clinical and surgical outcomes after a 3 years' experience of robotic assisted UKA with the Mako Robotic Arm. METHODS: Seventy-three patients undergoing  UKA with robotic instrumentation (65 medial UKAs, 8 lateral UKAs) and with a clinical follow-up of 3 -37 months were included in the present study...
June 7, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/28649851/avoidance-of-urinary-catheterization-to-minimize-in-hospital-complications-after-transcatheter-aortic-valve-implantation-an-observational-study
#12
Sandra B Lauck, Jae-Yung Kwon, David A Wood, Jennifer Baumbusch, Tone M Norekvål, Nay Htun, Leo Stephenson, John G Webb
BACKGROUND: Contemporary transcatheter aortic valve implantation (TAVI) devices and approach present opportunities to review historical practices initially informed by early treatment development and cardiac surgery. The avoidance of urinary catheterization in the older TAVI population is a strategy to minimize in-hospital complications. The purpose of the study was to explore elimination-related complications following the phased implementation of a default strategy of avoiding urinary catheterization in patients undergoing transfemoral (TF) TAVI...
June 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28647798/a-new-model-for-biofilm-formation-and-inflammatory-tissue-reaction-intraoperative-infection-of-a-cranial-implant-with-staphylococcus-aureus-in-rats
#13
Silke Glage, Silke Paret, Andreas Winkel, Meike Stiesch, André Bleich, Joachim K Krauss, Kerstin Schwabe
BACKGROUND: Implant failure is a severe and frequent adverse event in all areas of neurosurgery. It often involves infection with biofilm formation, accompanied by inflammation of surrounding tissue, including the brain, and bone loss. The most common bacteria involved are Staphylococcus aureus. We here test whether intraoperative infection of intracranial screws with Staphylococcus aureus would lead to biofilm formation and inflammatory tissue reaction in rats. METHODS: Two titanium screws were implanted in the cranium of Sprague-Dawley rats, anesthetized with xylazine (4 mg/kg) and ketamine (75 mg/kg)...
June 25, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28646465/delayed-complications-of-deep-brain-stimulation-16-year-experience-in-249-patients
#14
Gustavo Fernández-Pajarín, A Sesar, B Ares, J L Relova, E Arán, M Gelabert-González, A Castro
BACKGROUND: Over the years, most of the deep brain stimulation (DBS) complications described have been mainly related to the surgery itself or the stimulation. Only a few authors have dealt with chronic complications or complications due to implanted material. METHODS: We retrospectively analyzed complications beyond the 1st month after surgery in 249 patients undergoing DBS at our site for 16 years, with 321 interventions overall. RESULTS: Our results show that infection is the most frequent delayed complication (12...
June 24, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28630749/imaging-in-peri-prosthetic-assessment-an-orthopaedic-perspective
#15
Christoph H Lohmann, Sanjiv Rampal, Martin Lohrengel, Gurpal Singh
As imaging techniques are ever-evolving, this article aims to provide a brief overview of the various modalities including their limitations. The ability of imaging for evaluation of implant osseo-integration will be addressed and also the role of imaging in assessing septic and aseptic loosening, with a particular focus on adverse tissue reactions, will be discussed. Specific features when imaging the big joints such as shoulder, hip, knee and ankle joint will also be outlined.Overall, a lack of standardisation and validity was noted and despite the gross variety of imaging modalities, there is no technique covering all aspects required for evaluation of implant fixation and septic and aseptic loosening...
May 2017: EFORT open reviews
https://www.readbyqxmd.com/read/28625077/microbiome-and-microbial-biofilm-profiles-of-peri-implantitis-a-systematic-review
#16
Gloria Inés Lafaurie, María Alejandra Sabogal, Diana Marcela Castillo, María Victoria Rincón, Luz Amparo Gómez, Yamil Augusto Lesmes, Leandro Chambrone
BACKGROUND: This systematic review assesses the microbiological profiles of peri-implantitis, periodontitis and healthy implants based on studies that evaluated microbial biofilms and entire microbiomes to establish their similarities and differences. METHODS: The Medical Literature Analysis and Retrieval System Online, via PubMed, EMBASE (Excerpta Medica Database) and Cochrane Central Register of Controlled Trials (CENTRAL) were searched without language restrictions through July 30, 2016...
June 19, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28598582/outcomes-of-intercalary-prosthetic-reconstruction-for-pathological-diaphyseal-femoral-fractures-secondary-to-metastatic-tumors
#17
Hong-Chao Huang, Yong-Cheng Hu, Deng-Xing Lun, Jun Miao, Feng Wang, Xiong-Gang Yang, Xin-Long Ma
OBJECTIVE: To evaluate the clinical outcomes and complications of segmental prosthetic reconstruction for pathological diaphyseal femoral fractures secondary to metastatic tumors. METHODS: Between 2011 and 2015, we retrospectively evaluated 16 patients (6 men and 10 women; 64.5 ± 11.4 years old at diagnosis) who underwent prosthetic reconstruction after segmental resection of diaphyseal femoral fractures due to metastatic lesions. Visual analog scale (VAS), functional outcomes, implant-related complications, and Mean postoperative Musculoskeletal Tumor Society (MSTS) score for each patient were collected...
May 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28571253/antibacterial-effects-of-garlic-extracts-and-ziziphora-essential-oil-on-bacteria-associated-with-peri-implantitis
#18
Farzane Pakdel, Shima Ghasemi, Amirreza Babaloo, Yousef Javadzadeh, Rosa Momeni, Milad Ghanizadeh, Seyyed Reza Moaddab, Farzad Yeganeh Fathi
INTRODUCTION: Peri-implantitis is an inflammatory process, characterized by loss of bone around implants and bleeding on probing. Colonization of bacteria in the pocket created around the implant is one of the most important aetiologic factors involved. Although antibiotics are routinely used and are effective agents against this bacterial infection, due to the side effects and drug resistance of these medications, researchers are more interested in using herbal derivatives. There are relatively limited number of studies in this respect...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28556531/effects-of-uncontrolled-periodontitis-on-marginal-bone-alterations-around-implants-a-case-control-study
#19
Xin Wang, Lei Qin, Chi Lei, Yu Li, Dehua Li
BACKGROUND: The hypothesis of bacterial infection initiating marginal bone loss around dental implant in analogy with natural tooth is still in debate. PURPOSE: The aim of this retrospective study was to investigate the effects of uncontrolled periodontitis on marginal bone alterations around implants compared with the periodontal health group at a mean follow-up of at least 6 years. MATERIALS AND METHODS: Thirty consecutive uncontrolled periodontally compromised patients (PCP) and 30 periodontally healthy patients (PHP), with a total of 96 Straumann implants (PCP = 55, PHP = 41) were matched for age, gender, smoking, and implant characteristics...
May 29, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28540566/-osteosynthesis-associated-infections-epidemiology-definition-and-diagnosis
#20
REVIEW
N Renz, S Feihl, C E Dlaska, M A Schütz, A Trampuz
Osteosynthesis-associated infections occur in 1-5% after closed and in up to 30% after open fractures. There are three different descriptions of implant-associated infections after fracture fixation, which are crucial for the selection of the adequate treatment strategy; temporal appearance from the index surgery (early versus late), pathogenesis of the infection (exogenous, hematogenous and contiguous from an adjacent focus), duration of infection symptoms (acute versus chronic). Diagnosis of osteosynthesis-associated infection is challenging, as chronic low-grade infections often present only with unspecific and subtle clinical symptoms...
June 2017: Der Unfallchirurg
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