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Peri-implant infection

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https://www.readbyqxmd.com/read/28316924/newer-proposed-classification-of-periimplant-defects-a-critical-update
#1
REVIEW
Deepak Passi, Mahinder Singh, Shubha Ranjan Dutta, Sarang Sharma, Mansi Atri, Jyoti Ahlawat, Abhinav Jain
The term peri-implantitis is used to describe a destructive inflammatory process affecting the soft and hard tissues around osseo integrated implants, leads to the formation of a peri-implant pocket and loss of supporting bone. Predisposing factors are Poor Plaque Control, inflammation, infection, Smoking, Diabetes and Occlusal Overload. It is diagnosed on the basis of clinical and radiographic interpretation and still no definite criteria have been proposed for the diagnosis and treatment of peri-implantitis...
January 2017: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/28296966/an-oral-multispecies-biofilm-model-for-high-content-screening-applications
#2
Nadine Kommerein, Sascha N Stumpp, Mathias Müsken, Nina Ehlert, Andreas Winkel, Susanne Häussler, Peter Behrens, Falk F R Buettner, Meike Stiesch
Peri-implantitis caused by multispecies biofilms is a major complication in dental implant treatment. The bacterial infection surrounding dental implants can lead to bone loss and, in turn, to implant failure. A promising strategy to prevent these common complications is the development of implant surfaces that inhibit biofilm development. A reproducible and easy-to-use biofilm model as a test system for large scale screening of new implant surfaces with putative antibacterial potency is therefore of major importance...
2017: PloS One
https://www.readbyqxmd.com/read/28291856/histologic-evaluation-of-sinus-grafting-materials-after-peri-implantitis-induced-failure-a-case-series
#3
Antonio Scarano, Anastasia Kelekis Cholakis, Adriano Piattelli
PURPOSE: This human case series presents the clinical and histologic results of five cases of peri-implantitis with subsequent sinus graft infections. Complications may follow maxillary sinus augmentation procedures. It is possible to have an inflammatory reaction, movement of the implant inside the sinus, formation of an insufficient quantity of osseous tissue, and the production of an oroantral fistula. Complications following maxillary subantral augmentation procedures are relatively rare; however, the risks and benefits of any surgery must be carefully evaluated at the onset...
March 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28291850/efficiency-of-nanotube-surface-treated-dental-implants-loaded-with-doxycycline-on-growth-reduction-of-porphyromonas-gingivalis
#4
Cimara Fortes Ferreira, Jegdish Babu, Azhang Hamlekhan, Sweetu Patel, Tolou Shokuhfar
PURPOSE: The prevalence of peri-implant infection in patients with dental implants has been shown to range from 28% to 56%. A nanotube-modified implant surface can deliver antibiotics locally and suppress periodontal pathogenic bacterial growth. The aim of this study was to evaluate the deliverability of antibiotics via a nanotube-modified implant. MATERIALS AND METHODS: Dental implants with a nanotube surface were fabricated and loaded with doxycycline. Afterward, each dental implant with a nanotube surface was placed into 2-mL tubes, removed from solution, and placed in a fresh solution daily for 28 days...
March 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28291188/quantification-of-peri-implant-bacterial-load-and-in-vivo-biofilm-formation-in-an-innovative-clinically-representative-mouse-model-of-periprosthetic-joint-infection
#5
Alberto V Carli, Samrath Bhimani, Xu Yang, Matthew B Shirley, Karen L de Mesy Bentley, F Patrick Ross, Mathias P G Bostrom
BACKGROUND: Periprosthetic joint infection (PJI) is a devastating complication following total joint arthroplasty. Current animal models of PJI are limited because of a lack of quantitative methods and failure to effectively recreate the periprosthetic space. We therefore developed a murine PJI model involving a 3-dimensionally printed Ti-6Al-4V implant capable of bearing weight and permitting quantitative analysis of periprosthetic bacterial load and evaluation of biofilm. METHODS: Twenty-five 12-week-old C57BL/6 mice received a unilateral proximal tibial implant and intra-articular injection of either 3 × 10 colony forming units (CFUs) of Staphylococcus aureus Xen 36 or saline solution...
March 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28255603/intraoperative-diagnosis-of-staphylococcus-aureus-and-coagulase-negative-staphylococcus-using-xpert-mrsa-sa-ssti-assay-in-prosthetic-joint-infection
#6
Andrea Sambri, Giovanni Pignatti, Matteo Romagnoli, Davide Donati, Maurilio Marcacci, Matteo Cadossi
The aim of this prospective study was to evaluate the performance of the Polymerase Chain Reaction (PCR) tool Xpert MRSA/SA SSTI test (Cepheid, Sunnyvale, CA, USA) on periprosthetic samples from a cohort of patients with suspected prosthetic joint infection (PJI). Seventy adult patients were included in this prospective study. On the basis of the preoperative evaluation, 39 patients were clinically considered to have a PJI, whereas 31 were presumed to suffer from an aseptic mobilization of the implant. Xpert MRSA/SA SSTI identified 4 out of 4 MRSA, 7 out of 7 MSSA, and 14 out of 16 methicillin resistant CoNS...
March 1, 2017: New Microbiologica
https://www.readbyqxmd.com/read/28254551/in-silico-identification-of-a-therapeutic-target-for-photo-activated-disinfection-with-indocyanine-green-modeling-and-virtual-screening-analysis-of-arg-gingipain-from-porphyromonas-gingivalis
#7
Maryam Pourhajibagher, Abbas Bahador
BACKGROUND: Porphyromonas gingivalis is a momentous bacterial etiological agent associated with periodontitis, peri-implantitis as well as endodontic infections. The potential advantage of Photo-activated disinfection (PAD) as a promising novel approach is the choice of a suitable target site, specific photosensitizer, and wavelength of light for delivery of the light from source to target. Since Arg-gingipain is a cysteine proteinase that is involved in the virulence of P. gingivalis, it was evaluated as a target site for PAD with indocyanine green (ICG) as a photosensitizer...
February 27, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28218496/functional-analysis-of-bioactivated-surfaces
#8
Selgai Haidari, Marko Boskov, Ulrike Schillinger, Klaus-Dietrich Wolff, Christian Plank, Andreas Kolk
Common scaffold surfaces, such as titanium, can have side effects, e.g., infections, cytotoxicity, impaired osseointegration or low regeneration rates for bone tissue. These effects lead to poor implant integration or even implant loss. Therefore, bioactive implants are promising instruments in tissue regeneration. Osteoinductive elements, such as growth factors and anti-infectives, support wound healing and bone growth and thereby enable faster osseointegration, even in elderly patients. In this study, titanium surfaces were coated with a poly-(D,L-lactide) (PDLLA) layer containing different concentrations of copolymer-protected gene vectors (COPROGs) to locally provide bone morphogenetic protein-2 (BMP-2) or activated anti-infective agents, such as chlorhexidine gluconate, triclosan and metronidazole, to prevent peri-implantitis...
February 20, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28212129/endoscopic-removal-of-a-dental-implant-from-maxillary-sinus
#9
Serkan Dundar, Turgut Karlidag, Erol Keles
The displacement of a dental implant into the maxillary sinus during surgery or after a period of use is a complication defined in the dental implant clinical practice. This complication arises primarily from inadequate bone height and peri-implant infection. Specifically, foreign objects in the maxillary sinus can cause sinusitis via impaired mucociliary flow and foreign body reactions, so they must be removed. Caldwell-Luc, transnasal, and intraoral endoscopic sinus surgeries have all been used to remove such foreign bodies and lesions from maxillary sinuses...
February 16, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28197990/a-chlorhexidine-releasing-epoxy-based-coating-on-titanium-implants-prevents-staphylococcus-aureus-experimental-biomaterial-associated-infection
#10
M Riool, A J Dirks, V Jaspers, L de Boer, T J Loontjens, C M van der Loos, S Florquin, I Apachitei, L N Rijk, H A Keul, S A Zaat
Prevention of biomaterial-associated infections (BAI) remains a challenging problem, in particular due to the increased risk of resistance development with the current antibiotic-based strategies. Metallic orthopaedic devices, such as non-cemented implants, are often inserted under high mechanical stress. These non-cemented implants cannot be protected by e.g. antibioticreleasing bone cement or other antimicrobial approaches, such as the use of bioactive glass. Therefore, in order to avoid abrasion during implantation procedures, we developed an antimicrobial coating with great mechanical stability for orthopaedic implants, to prevent Staphylococcus aureus BAI...
February 14, 2017: European Cells & Materials
https://www.readbyqxmd.com/read/28186870/total-hip-arthroplasty-via-the-direct-anterior-approach-with-kerboull-type-acetabular-reinforcement-device-for-an-elderly-female-with-factor-xi-deficiency
#11
Kei Sano, Yasuhiro Homma, Tomonori Baba, Jun Ando, Mikio Matsumoto, Hideo Kobayashi, Takahito Yuasa, Kazuo Kaneko
We present a case of successful and uncomplicated total hip arthroplasty with an acetabular reinforcement device in an elderly patient with hip osteoarthritis already diagnosed with factor XI deficiency, which is a very rare bleeding disorder and at high risk of post-operative haemorrhage, and it poses a substantial challenge to surgeons as a consequence of the specific risks of infection and fixation failure. Moreover, bone fragility in elderly patient increases potential risk of adverse event. Fresh frozen plasma was used to supplement factor XI activity...
2017: SICOT-J
https://www.readbyqxmd.com/read/28174400/-l-shaped-partial-upper-sternotomy-approach-for-aortic-valve-replacement
#12
Hiroshi Munakata, Noriko Oyama, Yu Murakami, Takahiro Yamazato, Noriyuki Abe, Katsuhito Mabuni, Tadao Kugai
Transcatheter aortic valve implantation is a recent innovation in the treatment of severe aortic stenosis. On the other hand, several reports suggested that minimally invasive aortic valve replacement (MICS-AVR) is likely to be associated with reduced postoperative discomfort and faster recovery. Of note, an upper partial sternotomy for isolated aortic valve replacement( L-shaped MICS-AVR) has been accepted as the most common approach to the MICS-AVR. Since October 2013, we have preformed L-shaped MICS-AVR at our hospital...
February 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28163085/novel-technique-for-proximal-bone-anchoring-of-penile-prosthesis-after-radial-forearm-free-flap-neophallus
#13
Andrew J Cohen, Raj R Bhanvadia, Joseph J Pariser, David M Hatcher, Lawrence J Gottlieb, Gregory T Bales
BACKGROUND: Penile prosthesis insertion allows individuals with a neophallus to achieve erectile function. Lack of corporal bodies to accommodate cylinders makes anchoring of any prosthesis challenging. Anchoring the device to pubic bone is one strategy to achieve proximal stabilization of the prosthesis. PURPOSE: To describe outcomes of bone anchoring of penile implant in a neophallus with an accompanying video focusing on operative technique and salient tips for surgeons performing these procedures...
February 2, 2017: Urology
https://www.readbyqxmd.com/read/28162855/histopathological-and-scanning-electron-microscopy-findings-of-retrieved-porous-polyethylene-implants
#14
S-Y Choi, H-I Shin, T-Y Kwon, T-G Kwon
Porous polyethylene (PPE) implants are biocompatible alloplastic materials commonly used for facial augmentation. However, the effect of sub-periosteal PPE application on the surrounding tissues has not been analyzed clearly. This report documents the case of a 22-year-old woman who underwent peri-alar augmentation with PPE to improve midface retrusion. Although no infection or inflammation occurred at the surgical site, the patient requested removal of the PPE implant for aesthetic reasons alone at 1 year after the surgery...
February 2, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28160028/one-stage-bilateral-implantation-of-a%C3%A2-calcar-guided-short-stem-in%C3%A2-total-hip-arthroplasty-minimally-invasive-modified-anterolateral-approach-in-supine-position
#15
K P Kutzner, S Donner, M Schneider, J Pfeil, P Rehbein
OBJECTIVE: One-stage bilateral, muscle-preserving, calcar-guided implantation technique through the modified minimally invasive anterolateral approach in supine position. INDICATIONS: Bilateral primary/secondary osteoarthritis of the hip; bilateral femoral head necrosis; ASA I-III. CONTRAINDICATIONS: ASA IV; severe osteoporosis, other factors jeopardizing stable anchorage of cementless, calcar-guided short-stem; infection. SURGICAL TECHNIQUE: Supine position...
February 3, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28131641/retrospective-comparative-analysis-of-cardiovascular-implantable-electronic-device-infections-with-and-without-the-use-of-antibacterial-envelopes
#16
COMPARATIVE STUDY
A Hassoun, E D Thottacherry, M Raja, M Scully, A Azarbal
BACKGROUND: Cardiovascular implantable electronic device (CIED) infections are associated with morbidity and mortality. Peri-operative systemic intravenous antibiotic prophylaxis reduces the rate of CIED infections. AIGISRx, a polymer envelope implanted with the CIED, releases minocycline and rifampin, and has been introduced to reduce infections. METHODS: Retrospective review of 184 patients who underwent CIED implantation was conducted. Ninety-two patients were implanted with an AIGISRx envelope (AIGISRx group) and 92 patients were not implanted with an AIGISRx envelope (control group)...
March 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28127324/effect-of-postoperative-amoxicillin-on-early-bacterial-colonization-of-peri-implant-sulcus-a-randomized-controlled-clinical-trial
#17
Neda Moslemi, Aysan Shahnaz, Abbas Bahador, Sepehr Torabi, Sanaa Jabbari, Zahra Alizadeh Oskouei
OBJECTIVES: With side effects of antibiotics taken into consideration, the necessity of antibiotic therapy after simple implant placement procedures is still a subject of debate and the existing literature on this topic is widely controversial. The aim of this study was to assess the effect of postoperative amoxicillin therapy on early colonization of peri-implant sulcus after implant placement. MATERIALS AND METHODS: In this randomized controlled clinical trial, 20 patients requiring simple implant placement were randomly allocated to test or control groups and received postoperative amoxicillin or placebo, respectively...
September 2016: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/28123297/a-decomposable-silica-based-antibacterial-coating-for-percutaneous-titanium-implant
#18
Jia Wang, Guofeng Wu, Xiangwei Liu, Guanyang Sun, Dehua Li, Hongbo Wei
Although percutaneous titanium implants have become one of the best choices as retainers in the facial defects, peri-implantitis still occurs at a significant rate. This unwanted complication occurs due to adhesion of bacteria and subsequent biofilm formation. To solve this problem, we have developed a novel antibiotic nanodelivery system based on self-decomposable silica nanoparticles. In this study, silica-gentamycin (SG) nanoparticles were successfully fabricated using an innovative one-pot solution. The nanoparticles were incorporated within a gelatin matrix and cross-linked on microarc-oxidized titanium...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28116449/-treatment-of-femoral-shaft-fractures-in-children-and-adolescents-%C3%A2-50%C3%A2-kg-a%C3%A2-retrospective-multicenter-trial
#19
M Rapp, R Kraus, P Illing, D W Sommerfeldt, M M Kaiser
BACKGROUND: Operative treatment of diaphyseal fractures of the femur in older children and adolescents remains controversial due to multiple surgical options and higher complication rates in single-center studies compared to younger children. This retrospective multicenter study aimed to register early and late complications in day-by-day treatment. MATERIAL AND METHODS: Sixteen hospitals with particular expertise in pediatric orthopedic trauma participated in this study...
January 23, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28116262/acetabular-prosthetic-protrusio-after-bipolar-hemi-arthroplasty-of-the-hip-case-report-and-review-of-the-literature
#20
Jason Bt Lim, Chia Liang Ang, Hee Nee Pang
INTRODUCTION: Bipolar hemi-arthroplasty of the hip is a commonly performed procedure in elderly patients with intra-capsular fracture of the neck of the femur with good short-term results for pain relief, return to activity and morbidity. The incidence of intra-pelvic prosthesis migration or protrusion is rare and one of the inciting factors is chronic low-grade sepsis. Acetabular prosthesis protrusion poses a difficult and challenging surgical problem due to surrounding neurovascular structures...
July 2016: Journal of Orthopaedic Case Reports
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