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Peri-implant infection

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https://www.readbyqxmd.com/read/29778881/polymerase-chain-reaction-pcr-based-methods-promising-molecular-tools-in-dentistry
#1
REVIEW
Shahriar Shahi, Sepideh Zununi Vahed, Nazanin Fathi, Simin Sharifi
Polymerase chain reaction (PCR) has become a popular diagnosis and research technique in dentistry. Several studies show that its high sensitivity and specificity allow it as a precise, efficient, and rapid method for detection, identification, and quantification of microorganism. Several genetic polymorphisms can be determined along with detection of immune and inflammatory markers, therefore providing the more accurate perception into the mechanisms underlying the dental and periodontal disease. This review paper discusses the application of PCR as a diagnostic technique in periodontology, endodontic infections, implant-related, and peri-implantitis infection, immune and inflammatory markers identification and genetic polymorphism as well as application of next generation sequencing and gene microarray technology in dentistry mentioned...
May 17, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29772991/reconstruction-plate-based-antibiotic-cement-spacers-clinical-outcomes-and-description-of-technique
#2
Aditya V Maheshwari, Robert Pivec, Roby Abraham, Qais Naziri
The standard of care for chronic deep peri-prosthetic hip infection is a two-stage exchange with placement of a temporary antibiotic cement spacer and treatment with intravenous antibiotics. Several commercially available cement spacer options exist. We report on a novel antibiotic spacer that may be an efficient, cost-effective alternative. Medical records of all patients treated for deep peri-prosthetic hip infection after total hip arthroplasty between 2004 and 2012 were reviewed. Each antibiotic spacer was constructed from a 12- to 16-hole recon plate bent to provide adequate soft tissue tension and a cement ball that matched the acetabulum...
2018: Journal of Long-term Effects of Medical Implants
https://www.readbyqxmd.com/read/29771975/development-and-characterization-of-an-oral-multispecies-biofilm-implant-flow-chamber-model
#3
Nadine Kommerein, Katharina Doll, Nico S Stumpp, Meike Stiesch
Peri-implant infections are the most common cause of implant failure in modern dental implantology. These are caused by the formation of biofilms on the implant surface and consist of oral commensal and pathogenic bacteria, which harm adjacent soft and hard tissues and may ultimately lead to implant loss. In order to improve the clinical situation, there has to be a better understanding of biofilm formation on abiotic surfaces. Therefore, we successfully developed a system to cultivate an oral multispecies biofilm model in a flow chamber system, optimized for the evaluation of biofilm formation on solid materials by direct microscopic investigation...
2018: PloS One
https://www.readbyqxmd.com/read/29758001/an-antimicrobial-peptide-loaded-gelatin-chitosan-nanofibrous-membrane-fabricated-by-sequential-layer-by-layer-electrospinning-and-electrospraying-techniques
#4
Yuzhu He, Yahui Jin, Xiumei Wang, Shenglian Yao, Yuanyuan Li, Qiong Wu, Guowu Ma, Fuzhai Cui, Huiying Liu
Guided bone regeneration (GBR) technique is widely used in the treatment of bone defects caused by peri-implantitis, periodontal disease, etc. However, the GBR membranes commonly used in clinical treatments currently have no antibacterial activity. Therefore, in this study, sequential layer-by-layer electrospinning and electrospraying techniques were utilized to prepare a gelatin (Gln) and chitosan (CS) composite GBR membrane containing hydroxyapatite nanoparticles (nHAp) and antimicrobial peptide (Pac-525)-loaded PLGA microspheres (AMP@PLGA-MS), which was supposed to have osteogenic and antibacterial activities...
May 14, 2018: Nanomaterials
https://www.readbyqxmd.com/read/29753881/confocal-fluorescence-imaging-to-evaluate-the-effect-of-antimicrobial-photodynamic-therapy-depth-on-p-gingivalis-and-t-denticola-biofilms
#5
Stephen Rogers, Kiyonobu Honma, Thomas S Mang
BACKGROUND: Porphyromonas gingivalis and Treponema denticola are both principally implicated in the incidence of both periodontal disease and peri-implantitis. Recent studies have demonstrated that these bacteria exhibit symbiotic growth in vitro and a synergistic virulence in co-infection of animal models. Found at varying depths throughout the biofilm, these bacteria present a significant challenge to traditional antimicrobial treatment modalities. Antimicrobial photodynamic therapy ( aPDT ) has yielded high success against bacterial biofilms, namely those found in the oral cavity...
May 10, 2018: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/29730314/comparison-of-infrapubic-vs-penoscrotal-approaches-for-3-piece-inflatable-penile-prosthesis-placement-do-we-have-a-winner
#6
REVIEW
Franco Palmisano, Luca Boeri, Cristiano Cristini, Gabriele Antonini, Matteo Giulio Spinelli, Giorgio Franco, Fabrizio Longo, Franco Gadda, Fulvio Colombo, Emanuele Montanari
BACKGROUND: The 3-piece inflatable penile prosthesis (IPP) is the gold standard treatment for male erectile dysfunction when other less invasive approaches are contra-indicated or unacceptable for the patient. There are currently 2 surgical approaches for IPP implantation: the penoscrotal (PS) and the infrapubic (IP) incision. AIM: To assess the most recent evidence on the impact of surgical approach for 3-piece IPP implantation in patients with erectile dysfunction...
May 2, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29718532/the-subcutaneous-implantable-cardioverter-defibrillator-a-tertiary-center-experience
#7
Cesar Khazen, Peter Magnusson, Johannes Flandorfer, Christoph Schukro
BACKGROUND: The aim of the study was to evaluate subcutaneous implantable cardioverter-defibrillator (S-ICD) patients with regard to underlying etiology, peri-procedural outcome, appropriate/inappropriate shocks, and complications during follow-up. METHODS: All patients who underwent S-ICD implantation from February 2013 to March 2017 at an academic hospital in Vienna were included. Medical records were examined and follow-up interrogations of devices were conducted...
May 2, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29717484/microbiologic-effect-of-two-topical-anti-infective-treatments-on-ligature-induced-peri-implantitis-a-pilot-study-in-dogs
#8
Umberto Demoner Ramos, Flavia Suaid, Ulf Me Wikesjö, Cristiano Susin, Patrícia Conde Vital, Sérgio Luis Scombatti de Souza, Michel Reis Messora, Daniela Bazan Palioto, Arthur Belém Novaes
BACKGROUND: The aim of this split-mouth design pilot study was to assess microbiologic effects of two topical anti-infective treatment protocols on dental implants subject to ligature-induced peri-implantitis in dogs, without the use of systemic antibiotics. METHODS: Eight adult Beagle dogs each received four dental implants in contralateral edentulated mandibular jaw quadrants. After 8 wks, silk ligatures were installed to be removed following another 8 wks. After additional 6 wks induced peri-implantitis lesions were subject to either antimicrobial photodynamic therapy (aPDT) or a topical tetracycline HCL (50 mg/mL) solution...
May 1, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/29709241/in-vitro-and-in-vivo-studies-of-anti-bacterial-copper-bearing-titanium-alloy-for-dental-application
#9
Rui Liu, Yulong Tang, Lilan Zeng, Ying Zhao, Zheng Ma, Ziqing Sun, Liangbi Xiang, Ling Ren, Ke Yang
OBJECTIVE: A novel copper-bearing titanium alloy (Ti-Cu) was fabricated for dental application that is expected to efficiently restrain the growth of bacteria and discourage biofilm formation. The aim of this study was to investigate both the antibacterial activity and biofilm inhibition of Ti-Cu alloy in vitro, and the antibacterial effect of Ti-Cu implant in early stage of peri-implantitis in vivo. METHODS: Staphylococcus aureus and Escherichia coli were selected to evaluate the antibacterial activity of Ti-Cu alloy and Ti served as control...
April 27, 2018: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29706210/influence-of-antibiotic-prophylaxis-on-the-stability-of-orthodontic-microimplants-a-pilot-randomized-controlled-trial
#10
RANDOMIZED CONTROLLED TRIAL
Jan Łyczek, Beata Kawala, Joanna Antoszewska-Smith
INTRODUCTION: The aims of this 2-arm parallel pilot randomized controlled trial were to investigate the influence of antibiotic prophylaxis on the stability of orthodontic microimplants and to evaluate the efficacy of systemic inflammatory marker measurements in detecting infections in tissues surrounding microscrews. METHODS: Orthodontic patients requiring en-masse distalization in the maxilla received antibiotics or a placebo before microimplant placement. Eligibility criteria included 13 years of age, and good general and oral health...
May 2018: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/29665602/the-use-of-bioactive-glass-s53p4-as-bone-graft-substitute-in-the-treatment-of-chronic-osteomyelitis-and-infected-non-unions-a-retrospective-study-of-50-patients
#11
Tarek Al Malat, Martin Glombitza, Janosch Dahmen, Peter-Michael Hax, Eva Steinhausen
BACKGROUND: Treatment of chronic osteomyelitis (COM) remains challenging and often results in large bone defects. Dead space management and proper defect filling are essential for successful treatment. Bioactive glass S53P4 (BAG-S53P4) is an anorganic bone graft substitute with antibacterial, osteoconductive, osteostimulative and angiogenic properties. The aim of our study was to analyse the outcome of patients with COM and infected non-unions, whose bone defects were filled with BAG-S53P4...
April 2018: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29609540/cost-benefit-analysis-of-antibiofilm-microbiological-techniques-for-peri-prosthetic-joint-infection-diagnosis
#12
Carlo L Romanò, Maria Teresa Trentinaglia, Elena De Vecchi, Nicola Logoluso, David A George, Ilaria Morelli, Lorenzo Drago
BACKGROUND: Implant-related infections, including those of peri-prosthetic joint (PJIs), osteosynthesis and other biomaterials, are biofilm-related. Pathogen identification is considered the diagnostic benchmark; however, the presence of bacterial biofilms makes pathogen detection with traditional microbiological techniques only partially effective. To improve microbiological diagnostic accuracy, some biofilm debonding techniques have been recently proposed. Aim of this health economics assessment study was to evaluate their economic impact on hospital costs...
April 2, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29608404/apicoectomy-and-sem-analysis-of-an-implant-infected-by-apical-retrograde-peri-implantitis-a-case-letter
#13
Rafael Manfro, Gislaine Felipe Garcia, Marcelo Carlos Bortoluzzi, Vinicius Fabris, Atais Bacchi, Carlos Nelson Elias
No abstract text is available yet for this article.
April 2, 2018: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29556679/-infections-after-reconstructive-spinal-interventions-how-do-i-deal-with-them
#14
REVIEW
Burkhard Lehner, Michael Akbar, Nicholas A Beckmann
BASICS: Postoperative surgical site infections of the spine have been described in up to 20% of patients and can result in serious consequences for the patient and substantial treatment costs. Typical bacteria often arise from skin or fecal flora. Various risk factors for infection have been described, including obesity, diabetes, high ASA scores, as well as intraoperative factors such as heavy blood loss, dural tears, or several revision procedures. Consequently, the prophylaxis with pre- and postoperative risk minimization is of particular importance...
March 20, 2018: Der Orthopäde
https://www.readbyqxmd.com/read/29549387/one-stage-exchange-with-antibacterial-hydrogel-coated-implants-provides-similar-results-to-two-stage-revision-without-the-coating-for-the-treatment-of-peri-prosthetic-infection
#15
Nicola Capuano, Nicola Logoluso, Enrico Gallazzi, Lorenzo Drago, Carlo Luca Romanò
PURPOSE: Aim of this study was to verify the hypothesis that a one-stage exchange procedure, performed with an antibiotic-loaded, fast-resorbable hydrogel coating, provides similar infection recurrence rate than a two-stage procedure without the coating, in patients affected by peri-prosthetic joint infection (PJI). METHODS: In this two-center case-control, study, 22 patients, treated with a one-stage procedure, using implants coated with an antibiotic-loaded hydrogel [defensive antibacterial coating (DAC)], were compared with 22 retrospective matched controls, treated with a two-stage revision procedure, without the coating...
March 16, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29544919/duration-of-hospital-admission-need-of-on-demand-analgesia-and-other-peri-procedural-and-short-term-outcomes-in-sub-cutaneous-vs-transvenous-implantable-cardioverter-defibrillators
#16
Serge Boveda, Tej Elbanet Chalbia, Sophie Jacob, Stéphane Combes, Nicolas Combes, Christelle Cardin, Guillaume Laborie, Maria Joao Sousa, Zeynab Jebberi, Sophia Mzoughi, Jean-Paul Albenque, Rui Providencia
BACKGROUND: Post-procedural recovery following sub-cutaneous ICD (S-ICD) implantation is feared to be more painful and to require more prolonged hospital admission. The purpose of this study was to compare peri-procedural and short clinical outcomes of the S-ICD vs. the Transvenous ICD (TV-ICD). METHODS: We conducted a single-center cross-sectional study including all consecutive patients who underwent S-ICD implantation by the same operator since January 2016 and a gender and age-matched control group with all single chamber TV-ICD implanted patients over a contemporary time period...
May 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29534130/single-dose-bioavailability-for-prophylactic-coverage-in-patients-undergoing-dental-implant-surgery
#17
Pedro C Aravena, Camila P Oyarzún, María F Arias, Héctor Monardes, Alejandro Jerez, Bruna Benso
PURPOSE: The use of antibiotic prophylaxis in dental implant surgery is a routine dental practice to prevent implant failure. Current systematic reviews have yet to confirm the effectiveness of antibiotic treatment at reducing postoperative infection rates in implant procedures. The aim of this study was to quantify amoxicillin plasma levels at the peripheral venous blood and at the surgical implant site in patients undergoing dental treatment. MATERIALS AND METHODS: A prospective study was conducted...
March 2018: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29533729/five-year-survival-of-short-single-tooth-implants-6-mm-a-randomized-controlled-clinical-trial
#18
N Naenni, P Sahrmann, P R Schmidlin, T Attin, D B Wiedemeier, V Sapata, C H F Hämmerle, R E Jung
The aim of the present study was to evaluate whether 6-mm dental implants in the posterior segments of either jaw perform equally well in terms of clinical and radiographic outcomes when compared with 10-mm implants after 5 y of loading. Patients with single-tooth gaps in the posterior area who were scheduled for implant therapy were randomly assigned to a group receiving either a 6- or 10-mm implant. After a healing period of 10 wk, implants were loaded with a screw-retained single crown and followed up at yearly intervals...
March 1, 2018: Journal of Dental Research
https://www.readbyqxmd.com/read/29520941/in-vitro-evaluation-of-controlled-release-14-doxycycline-gel-for-decontamination-of-machined-and-sandblasted-acid-etched-implants
#19
Giuseppe Patianna, Nicola Alberto Valente, Antonio D'Addona, Sebastiano Andreana
BACKGROUND: Peri-implant infections are associated with the establishment and maturation of a bacterial biofilm characterized by a predominance of Gram-negative fusiform anaerobic species. The decontamination of implant surfaces is then crucial for a successful peri-implant therapy. METHODS: Twenty-one smooth and 21 rough implants, divided into four groups according to surface and treatment modality, were contaminated with Streptococcus sanguinis and then placed in an incubator with the atmosphere of 5% CO2 at 37°C for 24 hours to allow the bacteria to grow...
March 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/29520781/effects-of-d-valine-on-periodontal-or-peri-implant-pathogens-porphyromonas-gingivalis-biofilm
#20
Hua Qi, Baosheng Li, Heling Wang, Qing Cai, Xu Quan, Yunxia Cui, Weiyan Meng
BACKGROUND: When presented with a surface or an interface, bacteria often grow as biofilms in which cells are held together by an extracellular matrix. Biofilm formation on implants is an initiating factor for their failure. Porphyromonas gingivalis is the primary etiologic bacteria of initiation and progression of periodontal disease. This microorganism is also the risk factor of many systemic diseases, such as cardiovascular disease, diabetes, and pulmonary infection. To date, no medication that can remove such biofilm has been accepted for clinical use...
March 2018: Journal of Periodontology
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