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https://www.readbyqxmd.com/read/28814294/canine-intrathoracic-sarcoma-with-ultrastructural-characteristics-of-human-synovial-sarcoma-case-report
#1
Ser Lovell, R K Burchell, P J Roady, R L Fredrickson, A Gal
BACKGROUND: Canine joint sarcomas, designated synovial sarcomas, are uncommon malignant mesenchymal neoplasms that occur in the large joints of the extremities of middle-aged, large-breed dogs. We report the diagnosis of an intrathoracic sarcoma with ultrastructural characteristics reminiscent of human synovial sarcoma in a dog. CASE PRESENTATION: A 7-year-old female spayed Tibetan terrier crossbred dog was presented for acute severe labored breathing and diagnosed with an intrathoracic neoplastic mass...
August 16, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28814191/maternal-overweight-disrupts-the-sexual-maturation-of-the-offspring
#2
Rocío A Galarza, Eric A Rhon Calderón, Analía E Cortez, Alicia G Faletti
The aims of the present work were to study the effect of maternal overweight and obesity on the ovarian reserve, follicular development, and ovulation of the offspring and to assess whether this maternal condition alters oocyte integrity. To this end, female offspring from rats fed standard (OSD) or cafeteria (OCD) diet were used. Body weight, vaginal opening, and estrous cycle were recorded and ovaries were obtained on the day of the second estrus. In addition, ovarian weight, ovulation rate (measured by the number of oocytes within oviducts), follicular development (determined by histology), and oocyte integrity were examined...
September 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28814138/finnish-nurses-attitudes-towards-their-role-in-the-euthanasia-process
#3
Anja Terkamo-Moisio, Chris Gastmans, Olli-Pekka Ryynänen, Anna-Maija Pietilä
BACKGROUND: Nurses' voices remain unheard in most debates about euthanasia, although their crucial role in the euthanasia process is widely acknowledged. Moreover, in Canadian euthanasia law, nurses have a more active role, which further highlights the need for knowledge about nurses' attitudes towards their role in the euthanasia process. RESEARCH QUESTIONS: What are Finnish nurses' attitudes towards their potential role in the euthanasia process? Which characteristics are associated with those attitudes? RESEARCH DESIGN: Cross-sectional web-based survey...
January 1, 2017: Nursing Ethics
https://www.readbyqxmd.com/read/28808193/evaluation-of-atherosclerotic-lesions-in-cholesterol-fed-mice-during-treatment-with-paclitaxel-in-lipid-nanoparticles-a-magnetic-resonance-imaging-study
#4
Aline D Lima, Ning Hua, Raul C Maranhão, James A Hamilton
Cholesterol-core nanoparticles (LDE) have been shown to be recognized by low-density lipoprotein receptors (LDLR) after administration; therefore, LDE is an ideal vehicle to deliver drug with targeting property. Paclitaxel, when incorporated into LDE, promotes atherosclerosis regression with reduced drug toxicity in rabbits through LDLR. Here, we tested whether LDE-paclitaxel could still be effective in reducing diet-induced atherosclerosis in a mouse model without LDLR. Nineteen LDLR knockout male mice were fed 1% cholesterol for 12 weeks...
January 19, 2017: Journal of Biomedical Research
https://www.readbyqxmd.com/read/28805256/effects-of-euthanasia-methods-on-stable-carbon-%C3%AE-13-c-value-and-nitrogen-%C3%AE-15-n-value-isotopic-composition-of-fry-and-juvenile-rainbow-trout-oncorhynchus-mykiss
#5
Sarah Nahon, Sarah Séité, Joanna Kolasinski, Pierre Aguirre, Inge Geurden
RATIONALE: Carbon and nitrogen stable isotope analyses of fish tissues are now commonly used in ecological studies but mostly require the sacrifice of the animal. Ethical considerations recommend the use of anesthetics for tissue sampling. This study examines how anesthetics affect stable isotope ratios of fish compared with other euthanasia methods. METHODS: Rainbow trout fry and juveniles were sacrificed using ice-freezing (as this common method used to kill fish does not affect natural isotopic ratios), electronarcosis or an overdose of chemical anesthetics (2-phenoxyethanol, benzocaine and clove oil)...
August 14, 2017: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/28803015/calf-and-replacement-heifer-mortality-from-birth-until-weaning-in-pasture-based-dairy-herds-in-new-zealand
#6
E L Cuttance, W A Mason, J McDermott, R A Laven, S McDougall, C V C Phyn
The aims of this study were to (1) estimate the perinatal (birth to 24 h) and postnatal (∼24 h to the mean weaning age of 13 wk) mortality risk in pasture-based dairy calves until weaning, and (2) identify associated risk factors in the 2015 calving season. A prospective survey of 32 seasonal calving dairy farms was undertaken. Farmers recorded (daily) the number and sex of the calves alive or dead in the paddocks where cows calved. All daily animal movements in and out of the calf rearing facilities, including death and euthanasia, and the identification of the animals (if applicable) were recorded, and a survey of the farm management practices was undertaken...
August 9, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28801443/the-provision-of-medical-assistance-in-dying-protocol-for-a-scoping-review
#7
Simon J W Oczkowski, Ian Ball, Carol Saleh, Gaelen Kalles, Anatoli Chkaroubo, Mike Kekewich, Paul Miller, Marianne Dees, Andrea Frolic
INTRODUCTION: Medical assistance in dying (MAID), a term encompassing both euthanasia and assisted suicide, was decriminalised in Canada in 2015. Although Bill C-14 legislated eligibility criteria under which patients could receive MAID, it did not provide guidance regarding the technical aspects of providing an assisted death. Therefore, we propose a scoping review to map the characteristics of the existing medical literature describing the medications, settings, participants and outcomes of MAID, in order to identify knowledge gaps and areas for future research...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28799288/neuroprotective-activity-of-cannabinoid-receptor-2-against-oxidative-stress-and-apoptosis-in-rat-pups-having-experimentally-induced-congenital-hypothyroidism
#8
Mehmet Eray Alcigir, Halef Okan Dogan, Sevil Atalay Vural, Fatma Meriç Yilmaz
In this study, it was aimed to show the cannabinoid receptor-2 (CB2) role, which is a part of neuroprotective endocannabinoidal system, against increasing nitric oxide synthetase (iNOS, eNOS) levels and the apoptotic activity (caspase-3, caspase-9 and DNA in situ fragmentation) within the postnatal critical period in pups of pregnant rats with artificially induced maternal thyroid hormone (TH) deficiency. Each of the 3 groups established comprised 1 male and 2 female rats, and they were coupled. Their pups were used...
August 11, 2017: Developmental Neurobiology
https://www.readbyqxmd.com/read/28793837/further-investigation-of-equine-fescue-oedema-induced-by-mediterranean-tall-fescue-lolium-arundinaceum-infected-with-selected-fungal-endophytes-epichlo%C3%A3-coenophiala
#9
S C Finch, J S Munday, B L Sutherland, J B Vlaming, L R Fletcher
AIMS: To determine if equine fescue oedema (EFO) induced by grazing Mediterranean-type tall fescue (Lolium arundinaceum) infected with selected endophytes (Epichloë coenophiala) could be prevented by treatment with the corticosteroid, methylprednisolone, and anti-histamine cetirizine, and to determine concentrations of lolines, specifically N-acetyl norloline (NANL), in grasses grazed by horses that did and did not develop EFO. METHODS: Four horses were grazed on AR542-infected Mediterranean tall fescue pasture (from Day 0) for 7 days prior to being subjected to euthanasia...
August 9, 2017: New Zealand Veterinary Journal
https://www.readbyqxmd.com/read/28793032/protein-from-hevea-brasiliensis-hev-b-13-latex-attenuates-systemic-inflammatory-response-and-lung-lesions-in-rats-with-sepsis
#10
L A Araújo, P R Melo-Reis, F Mrue, C M Gomes, M A P Oliveira, H M Silva, M M Alves, N J Silva-Júnior
Sepsis induces a severe systemic inflammatory response that may result in multiple organ dysfunction and death. Studies using a protein derived from natural Hevea brasiliensis (rubber tree) latex, denominated Hev b 13, have demonstrated important anti-inflammatory effects, but no data have been published regarding its effects on sepsis. The aim of this study was to investigate the effects of Hev b 13 on the inflammatory response and lung lesions of septal rats. Male Wistar rats were submitted to cecal ligation and puncture (CLP), randomized into groups and treated with subcutaneously administered doses of 0...
July 27, 2017: Brazilian Journal of Biology, Revista Brasleira de Biologia
https://www.readbyqxmd.com/read/28792626/advanced-three-dimensional-culture-of-equine-intestinal-epithelial-stem-cells
#11
A Stieler Stewart, J M Freund, L M Gonzalez
BACKGROUND: Intestinal epithelial stem cells are critical to epithelial repair following gastrointestinal injury. The culture of intestinal stem cells has quickly become a cornerstone of a vast number of new research endeavours that range from determining tissue viability to testing drug efficacy for humans. This study aims to describe the methods of equine stem cell culture and highlights the future benefits of these techniques for the advancement of equine medicine. OBJECTIVES: To describe the isolation and culture of small intestinal stem cells into three-dimensional (3D) enteroids in horses without clinical gastrointestinal abnormalities...
August 9, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28789711/does-growth-restriction-increase-the-vulnerability-to-acute-ventilation-induced-brain-injury-in-newborn-lambs-implications-for-future-health-and-disease
#12
B J Allison, S B Hooper, E Coia, G Jenkin, A Malhotra, V Zahra, A Sehgal, M Kluckow, A W Gill, T Yawno, G R Polglase, M Castillo-Melendez, S L Miller
Fetal growth restriction (FGR) and preterm birth are frequent co-morbidities, both are independent risks for brain injury. However, few studies have examined the mechanisms by which preterm FGR increases the risk of adverse neurological outcomes. We aimed to determine the effects of prematurity and mechanical ventilation (VENT) on the brain of FGR and appropriately grown (AG, control) lambs. We hypothesized that FGR preterm lambs are more vulnerable to ventilation-induced acute brain injury. FGR was surgically induced in fetal sheep (0...
August 9, 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/28782218/was-sigmund-freud-s-death-hastened
#13
Alastair D Sandy Macleod
The terminal illness of Sigmund Freud has been considered by many authors to be an example of physician-enacted euthanasia. A review and a reconsideration of the published literature by Freud's doctors and biographers cast doubt on this opinion. Over his last 48 h, Freud was administered substantial morphine doses to sedate and relieve his pain. However, from a pharmacological perspective, the timing of his death would not be consistent with that of a fatal dose of opioid. Freud died a natural death.
August 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28776069/porcine-arteriogenesis-based-on-vasa-vasorum-in-a-novel-semi-acute-occlusion-model-using-high-resolution-imaging
#14
Jonathan M Harnoss, Florian Krackhardt, Zully Ritter, Susanne Granzow, Dieter Felsenberg, Konrad Neumann, Lilach O Lerman, Fabian Riediger, Philipp Hillmeister, Peter Bramlage, Ivo R Buschmann
Bridging collaterals (BC) develop in several chronic total artery occlusion diseases, and can prevent extensive myocardial necrosis. Yet, their origin, growth process, and histo-morphology are still unclear. Since vasa vasorum (VV) may take part in collateralization, we hypothesized that VV are the basis for BCs. To comprehensively investigate this arteriogenesis process, we used high-resolution imaging, including corrosion casts, post-mortem angiography with stereoscopy, micro-CT, and immunohistology, in combination with a novel semi-acute vessel occlusion model...
August 3, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28775037/low-volume-pentobarbital-for-euthanasia
#15
(no author information available yet)
No abstract text is available yet for this article.
August 5, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28774942/on-farm-euthanasia-practices-and-attitudes-of-commercial-meat-rabbit-producers
#16
Jessica Walsh, Aaron Percival, Brian Tapscott, Patricia V Turner
Appropriate and timely on-farm euthanasia is the responsibility of the producer, working together with their herd veterinarian. Unfortunately, validated methods for euthanasia of commercial meat rabbits are lacking and there are few educational materials available for producer training. Because euthanasia must be performed in a timely fashion to minimise suffering, it is critical to ensure that methods used are aesthetic, humane and effective. We surveyed Canadian meat rabbit producers for current on-farm euthanasia practices as well as attitudes towards the methods they employed and thoughts on novel euthanasia techniques...
August 3, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28774941/transmission-of-mycobacterium-xenopi-to-a-pet-albino-ferret-mustela-putorius-furo-from-a-domestic-aquarium
#17
Natasha Davendralingam, Indran Davagnanam, Mark Frederick Stidworthy, Vicki Baldrey, Laureen Michele Peters, Nadene Stapleton
A three-year-old ferret presented with a three-month history of rapid clinical deterioration necessitating euthanasia shortly after initial veterinary assessment. Postmortem PCR testing confirmed Mycobacterium xenopi which is most commonly identified in amphibians, reptiles and aquatic life. Infection of a captive-bred domestic ferret is highly unusual. A collaborative effort involving medical doctors, clinical veterinarians and veterinary pathologists investigated the potential sources of human-animal, animal-animal and environmental-animal M xenopi transmission...
August 3, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28772215/treatment-with-tucum%C3%A3-oil-astrocaryum-vulgare-for-diabetic-mice-prevents-changes-in-seric-enzymes-of-the-purinergic-system-improvement-of-immune-system
#18
Matheus D Baldissera, Carine F Souza, Pedro H Doleski, Thirssa H Grando, Michele R Sagrillo, Aleksandro S da Silva, Daniela B R Leal, Silvia G Monteiro
The aim of this study was to evaluate the enzymatic activity of the purinergic system in sera samples from alloxan-induced diabetic mice treated with tucumã oil (Astrocaryum vulgare). For this, the mice were divided into four groups (n=6): control/water (the group CW); control/tucumã oil (the group CT); diabetic/water (the group DW), and diabetic/tucumã oil (the group DT) treated for 14days with 5.0mLkg(-1) via oral gavage. On day 14 post-treatment, mice were submitted to euthanasia and blood samples were collected by cardiac puncture...
July 31, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28769117/species-specific-anaesthetics-for-fish-anaesthesia-and-euthanasia
#19
Gareth D Readman, Stewart F Owen, Toby G Knowles, Joanna C Murrell
There is a need to ensure that the care and welfare for fish maintained in the laboratory are to the highest standards. This extends to the use of anaesthetics for both scientific study, humane killing and euthanasia at end of life. An anaesthetic should not induce negative behaviours and fish should not seek to avoid the anaesthetic. Surprisingly little information is available to facilitate a humane choice of anaesthetic agent for fish despite over 100 years of use and the millions of fish currently held in thousands of laboratories worldwide...
August 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28764714/testis-specific-histone-2b-is-associated-with-sperm-chromatin-dynamics-and-bull-fertility-a-pilot-study
#20
Naseer A Kutchy, Ana Velho, Erika S B Menezes, Marie Jacobsen, Giselle Thibaudeau, Robert W Wills, Arlindo Moura, Abdullah Kaya, Andy Perkins, Erdogan Memili
BACKGROUND: Bull fertility is the degree of sperm's ability to fertilize and activate the egg and support embryo development, and this is critical for herd reproductive performance. We used the bull as a unique model organism for the study of male fertility because cattle genetics and physiology is similar to those of other mammals including humans. Moreover, reliable fertility data along with well-established in vitro systems are available for bovine. The objective of this original study was to ascertain evolutionary diversification and expression dynamics of Testis Specific Histone 2B (TH2B) in sperm from Holstein bulls with different fertility scores...
August 1, 2017: Reproductive Biology and Endocrinology: RB&E
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