keyword
MENU ▼
Read by QxMD icon Read
search

Xerostomia

keyword
https://www.readbyqxmd.com/read/29664218/parotid-gland-radiation-dose-xerostomia-relationships-based-on-actual-delivered-dose-for-nasopharyngeal-carcinoma
#1
Jingjiao Lou, Pu Huang, Changsheng Ma, Yue Zheng, Jinhu Chen, Yueqiang Liang, Hongsheng Li, Yong Yin, Danhua Liu, Gang Yu, Dengwang Li
Xerostomia induced by radiotherapy is a common toxicity for head and neck carcinoma patients. In this study, the deformable image registration of planning computed tomography (CT) and weekly cone-beam CT (CBCT) was used to override the Hounsfield unit value of CBCT, and the modified CBCT was introduced to estimate the radiation dose delivered during the course of treatment. Herein, the beams from each patient's treatment plan were applied to the modified CBCT to construct the weekly delivered dose. Then, weekly doses were summed together to obtain the accumulated dose...
April 17, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29661437/development-of-routine-dental-care-for-liver-transplant-outpatients
#2
S V Nascimento, A M Gonzalez, B Aguiar Roza, C F M G Pimentel, J Schirmer, S Mucci, D C Abranches
BACKGROUND: Liver transplantation has become commonplace for patients with end-stage liver disease. The liver is a bodily organ of great importance, and its dysfunction can cause significant complications throughout the body. Patients with hepatic disease should be able to acquire knowledge of the physiology of the liver via the dental profession, and it is also necessary to modify some aspects of dental treatment even in healthy patients. Problems such as excessive bleeding and hepatotoxicity caused by some of the drugs used in dental treatment can lead to a decrease in systemic health...
April 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29657585/deterioration-in-saliva-quality-in-patients-with-sj%C3%A3-gren-s-syndrome-impact-of-decrease-in-salivary-epidermal-growth-factor-on-the-severity-of-intraoral-manifestations
#3
REVIEW
Naoto Azuma, Yoshinori Katada, Hajime Sano
Background: Sjögren's syndrome (SS) is a chronic inflammatory autoimmune disease characterized by lymphocytic infiltration of the exocrine glands, especially the salivary and lacrimal glands. As a result of salivary gland dysfunction, most patients with SS have xerostomia related to a reduced salivary flow rate. In addition to the discomfort due to xerostomia, dry mouth can cause various intraoral manifestations such as refractory stomatitis, ulcer, and atrophic changes in the oral mucosa and tongue, and the patient's quality of life (QoL) is severely impaired...
2018: Inflammation and Regeneration
https://www.readbyqxmd.com/read/29656422/role-of-lactoferrin-and-lactoferrin-derived-peptides-in-oral-and-maxillofacial-diseases
#4
REVIEW
Kabilan Velliyagounder, Dania Bahdila, Siddhi Pawar, Daniel H Fine
The oral cavity harbors different taxonomic groups, the evolutionary co-existence of which develops the oral ecosystem. These resident microorganisms can alter the balance between the physiologic and pathologic conditions that affect the host, both locally and systemically. This highly sophisticated nature of the oral cavity poses a significant therapeutic challenge. Numerous human and animal studies have been conducted to potentiate the efficacy and competence of current treatments of pathologic conditions as well as to develop novel therapeutic modalities...
April 14, 2018: Oral Diseases
https://www.readbyqxmd.com/read/29645367/saliva-and-gastrointestinal-functions-of-mastication-taste-and-textural-perception-swallowing-and-initial-digestion
#5
Anne Marie Lynge Pedersen, Christiane E Sørensen, Gordon Proctor, Guy Carpenter
Saliva exerts multiple functions in relation to the initial digestive processes taking place in the upper parts of the gastrointestinal tract. Ingestion of food and beverages, in turn, is a strong stimulus for secretion of saliva with a differential composition depending on the neuronal stimulation pattern. This review paper provides insight into the mechanisms by which saliva acts in relation to taste, mastication, bolus formation, enzymatic digestion, and swallowing. Also the protective functions of saliva including maintenance of dental and mucosal integrity will be discussed as they indirectly influence the digestive process...
April 12, 2018: Oral Diseases
https://www.readbyqxmd.com/read/29620098/maintenance-of-the-spheroid-organization-and-properties-of-glandular-progenitor-cells-by-fabricated-chitosan-based-biomaterials
#6
Hao-Wei Lee, Ya-Chuan Hsiao, Tai-Horng Young, Tsung-Lin Yang
Dysfunctional salivary gland (SG) is an unsolved clinical challenge, which is presented as xerostomia. Cell therapy is a promising treatment for restoring SG function. Salispheres are spheroid cellular organizations derived from SG stem cells. Benefitting from these cellular organizations, SG stem cells can be expanded to regenerate SG. During in vitro culture, the spontaneous reorganization of salispheres may change the features of residing SG stem cells. Therefore, it is imperative to explore ways to maintain the spheroid structure of salispheres during cell expansion in vitro...
April 5, 2018: Biomaterials Science
https://www.readbyqxmd.com/read/29619560/dysphagia-and-oral-morbidities-in-chemoradiation-treated-head-and-neck-cancer-patients
#7
Yoshiaki Ihara, Michael A Crary, Aarthi Madhavan, David C Gregorio, Ikjae Im, Sarah E Ross, Giselle D Carnaby
This study prospectively evaluated relationships between oral morbidities and swallowing ability in head/neck cancer patients following chemoradiation therapy (CRT) and at 3 months following CRT. Thirty patients with confirmed head/neck cancer undergoing chemoradiation were assessed with a battery of swallowing measures and measures of oral morbidities related to chemoradiation (xerostomia, mucositis, pain, taste/smell, oral moisture). All measures were completed at baseline (within the first week of CRT), at 6 weeks (end of treatment), and at 3 months following chemoradiation...
April 4, 2018: Dysphagia
https://www.readbyqxmd.com/read/29614832/ixeris-dentata-extract-increases-salivary-secretion-through-the-regulation-of-endoplasmic-reticulum-stress-in-a-diabetes-induced-xerostomia-rat-model
#8
Kashi Raj Bhattarai, Hwa-Young Lee, Seung-Hyun Kim, Hyung-Ryong Kim, Han-Jung Chae
This study aimed to investigate the molecular mechanism of diabetes mellitus (DM)-induced dry mouth and an application of natural products from Ixeris dentata (IXD), a recently suggested regulator of amylase secretion in salivary cells. Vehicle-treated or diabetic rats were orally treated with either water or an IXD extract for 10 days to observe the effect on salivary flow. We found that the IXD extract increased aquaporin 5 (AQP5) and alpha-amylase protein expression in the submandibular gland along with salivary flow rate...
April 2, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29610453/sj%C3%A3-gren-s-syndrome-associated-with-fanconi-s-syndrome-and-osteomalacia
#9
Jorge O Gutierrez, Maria F Zurita, Luis A Zurita
BACKGROUND Sjögren's syndrome is a chronic inflammatory autoimmune disease, which is also known as sicca syndrome, due to the symptoms of dry eyes and dry mouth, and is associated with other connective tissue diseases and autoimmune diseases. Sjögren's syndrome can also be associated with renal involvement. Fanconi's syndrome is associated with impaired reabsorption in the proximal renal tubule associated with tubulointerstitial nephritis and is associated with renal tubular acidosis and hypophosphatemia...
April 3, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29607456/oral-health-and-chemotherapy-act-as-cofactors-in-malnutrition-in-the-elderly-with-other-cancers-than-head-and-neck-malignancies
#10
Nada El Osta, Lana El Osta, Claire Lassauzay, Marwan Ghosn, Stephanie Tubert-Jeannin, Martine Hennequin
OBJECTIVES: This study explores whether the chemotherapy regimen has a role in inducing oral health problems and malnutrition in elderly patients with other cancers than head and neck malignancies. MATERIAL AND METHODS: An observational cross-sectional study was designed to compare the relationships between oral health and nutritional status between four groups of elderly differing in cancer or chemotherapy regimen. Data were collected using a questionnaire including the Mini-Nutritional Assessment (MNA), the Geriatric Oral Health Assessment Index (GOHAI) and questions about perception of xerostomia...
April 2, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29604122/salivary-flow-and-xerostomia-in-patients-with-type-2-diabetes
#11
Esther Carramolino-Cuéllar, Dorina Lauritano, Francisco-Javier Silvestre, Francesco Carinci, Alberta Lucchese, Javier Silvestre-Rangil
BACKGROUND: Saliva is secreted by the major and minor salivary glands. There are a number of physiological factors that can reduce this secretion such as age, sex, body weight, number of teeth present in the mouth, or time of day. This decrease may also be caused by the use of certain drugs, radiotherapy for head and neck cancer, chronic rheumatic diseases such as Sjögren's syndrome, and other systemic disorders such as diabetes mellitus (DM). Objective of this study was to investigate the effect of type 2 DM on salivary secretion and its relation to the sensation of xerostomia...
March 31, 2018: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/29602165/sonographic-evaluation-of-salivary-glands-in-juvenile-sj%C3%A3-gren-s-syndrome
#12
Vanessa Ramos Guissa, Evelyne Lopes Martinelli, Letícia Maria Kolachinski Raposo Brandão, Leandro Diniz Garcia, José Roberto Provenza, José Alexandre Mendonça
IIntroduction: Sjögren's syndrome in childhood is a rare autoimmune disease and mostly under-diagnosed. The aim of this study is to highlight the importance of ultrasonographic assessment of the salivary glands in children with recurrent parotitis and positive autoantibodies. Two cases of ultrasonographic patterns typical of Sjögren's syndrome have been described below. Case 1: Female, 7 years old, reporting for 2 years recurrent parotitis, xerophthalmia, xerostomia, polyarthralgia and fever. Immunological tests were positive for antinuclear antibodies, rheumatoid factor, anti-SSA/Ro and anti-SSB/La...
January 2018: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/29600237/prospective-study-of-sequential-volumetric-changes-of-parotid-gland-in-early-oropharyngeal-carcinoma-patients-treated-by-intensity-modulated-radiation-therapy-an-institutional-experience
#13
Pooja Nandwani Patel, Sumit Goyal, Anand Shah, Mehul Gohel, Unnikrishnan Suryanarayana
Aims and Objectives: During course of radiation therapy, anatomical variations occur risking overdose of parotid gland. We tried to quantify volume of parotid gland and mean dose to parotid gland after every 10 fractions (#). Materials and Methods: We conducted the prospective study from July 2016 to May 2017 in 25 patients of early-stage oropharyngeal carcinoma. Patients had Karnofsy Performance Score of 80-100, median age was 54 years, and 18 patients were males...
January 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29599172/submandibular-gland-transfer-a-potential-imaging-pitfall
#14
X Wu, S S Yom, P K Ha, C M Heaton, C M Glastonbury
BACKGROUND AND PURPOSE: The Seikaly and Jha submandibular gland transfer surgery is performed to facilitate gland shielding during radiation therapy for head and neck tumors to circumvent radiation-induced xerostomia. It results in an asymmetric postsurgical appearance of the submandibular and submental spaces. Our purpose was to characterize the morphologic and enhancement characteristics of the transferred submandibular gland and identify potential pitfalls in postoperative radiologic interpretation...
March 29, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29579324/salvage-treatment-using-carbon-ion-radiation-in-patients-with-locoregionally-recurrent-nasopharyngeal-carcinoma-initial-results
#15
Jiyi Hu, Cihang Bao, Jing Gao, Xiyin Guan, Weixu Hu, Jing Yang, Chaosu Hu, Lin Kong, Jiade J Lu
BACKGROUND: Reirradiation for locoregionally recurrent nasopharyngeal carcinoma (NPC) after a definitive dose of radiotherapy (RT) is challenging and usually associated with severe toxicities. Intensity-modulated carbon ion RT (IMCT) offers physical/biologic advantages over photon-based intensity-modulated RT. Herein, the authors report their initial experience of IMCT in previously irradiated patients with locoregionally recurrent NPC. METHODS: Patients with locoregionally recurrent, poorly differentiated or undifferentiated NPC who underwent salvage therapy with IMCT at the Shanghai Proton and Heavy Ion Center between May 2015 and August 2017 were included in the current study...
March 26, 2018: Cancer
https://www.readbyqxmd.com/read/29577637/patient-s-perspective-on-long-term-complications-after-superficial-parotidectomy-for-benign-lesions-prospective-analysis-of-a-two-year-follow-up
#16
P Wolber, G F Volk, L Horstmann, M Finkensieper, S Shabli, C Wittekindt, J P Klussmann, O Guntinas-Lichius, D Beutner, M Grosheva
OBJECTIVE: Evaluation of patient's perspective on long-term complications after superficial parotidectomy for benign lesions. DESIGN: A prospective nonrandomized controlled multicenter study. SETTING: Three university-based tertiary referral centers (Departments of Otorhinolaryngology of Cologne, Jena and Giessen; all in Germany). PARTICIPANTS: 130 adult patients, who underwent a primary superficial parotidectomy for benign tumors of the parotid gland, were consecutively included from 09/2010 to 05/2012...
March 26, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29569726/xerostomia-salivary-characteristics-and-gland-volumes-following-intensity-modulated-radiotherapy-for-nasopharyngeal-carcinoma-two-year-follow-up
#17
Christina P C Sim, Yoke-Lim Soong, Eric P P Pang, Cindy Lim, Glenn D Walker, David J Manton, Eric C Reynolds, Joseph T S Wee
BACKGROUND: To evaluate changes in xerostomia status, salivary characteristics and gland volumes two years following radiotherapy in nasopharyngeal carcinoma patients. METHODS: Xerostomia scores, salivary flow rates, pH and buffering capacity were measured at pre-radiotherapy, mid-radiotherapy, two-weeks, three-months and two-years post-radiotherapy. Salivary gland volumes and their correlation with radiation dose were also assessed. RESULTS: Mean radiation dose to oral cavity, parotid and submandibular glands was 44...
March 23, 2018: Australian Dental Journal
https://www.readbyqxmd.com/read/29568026/insufficient-evidence-for-interventions-to-prevent-dry-mouth-and-salivary-gland-dysfunction-post-head-and-neck-radiotherapy
#18
Debra M Ferraiolo, Analia Veitz-Keenan
Data sourcesCochrane Oral Health's Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, CINAHL, EBSCO (Cumulative Index to Nursing and Allied Health Literature, LILACS, BIREME, Virtual Health Library (Latin American and Caribbean Health Science Information database), Zetoc Conference Proceedings, the US National Institutes of Health Ongoing Trials Register, (ClinicalTrials.gov) and the World Health Organization International Clinical Trials Registry Platform for ongoing trials...
March 23, 2018: Evidence-based Dentistry
https://www.readbyqxmd.com/read/29559836/orofacial-manifestations-and-temporomandibular-disorders-of-sj%C3%A3-gren-syndrome-an-observational-study
#19
Vito Crincoli, Mariasevera Di Comite, Mariateresa Guerrieri, Rossana Patricia Rotolo, Luisa Limongelli, Angela Tempesta, Florenzo Iannone, Angela Rinaldi, Giovanni Lapadula, Gianfranco Favia
AIMS : Sjӧgren Syndrome is a disorder involving oral tissues, with xerostomia, dysgeusia, dysphagia, tooth decay, gingivitis, angular cheilitis and glossitis. Temporomandibular disorders are a generic term referred to clinical conditions involving the jaw muscles and temporomandibular joint. The aim of this study was to investigate the prevalence of oral manifestations and temporomandibular disorders (TMD) in Sjӧgren Syndrome (SS) patients compared with healthy people. METHODS : The study group included 72 SS patients (2 men, 70 women) diagnosed according to the American-European Consensus Group (AECG) Criteria...
2018: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/29556926/nutrition-impact-symptoms-and-associated-outcomes-in-post-chemoradiotherapy-head-and-neck-cancer-survivors-a-systematic-review
#20
REVIEW
Sylvia L Crowder, Katherine G Douglas, M Yanina Pepino, Kalika P Sarma, Anna E Arthur
PURPOSE: It is estimated that more than 90% of head and neck cancer (HNC) survivors who underwent chemoradiotherapy experience one or more nutrition impact symptoms (NIS) in the months or years thereafter. Despite the high prevalence, there is limited research addressing long-term impact of NIS on outcomes such as nutrition and quality of life in HNC survivors treated with chemoradiotherapy. IMPLICATIONS FOR CANCER SURVIVORS: The prevalence and consequences of nutrition impact symptoms are substantial among head and neck cancer survivors beyond the acute phase of cancer treatment...
March 20, 2018: Journal of Cancer Survivorship: Research and Practice
keyword
keyword
97792
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"