keyword
MENU ▼
Read by QxMD icon Read
search

Dry mouth treatment

keyword
https://www.readbyqxmd.com/read/28431302/quality-of-life-in-survivors-of-oropharyngeal-cancer-a%C3%A2-systematic-review-and-meta-analysis-of-1366-patients
#1
REVIEW
Sanne Høxbroe Michaelsen, Christian Grønhøj, Jacob Høxbroe Michaelsen, Jeppe Friborg, Christian von Buchwald
Human papillomavirus (HPV)-associated oropharyngeal cancer (OPC) is rapidly increasing in incidence and has a favourable prognosis compared with HPV-negative disease. Current combined therapies include significant risks of morbidity for the growing group of survivors. This systematic review and meta-analysis investigates how treatment affects quality of life (QoL) in survivors of oropharyngeal cancer. PubMed, EMBASE and the Cochrane Library were systematically searched for all studies reporting patient-assessed QoL at least 1 year after treatment for OPC...
April 18, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28413925/triple-bead-mixed-amphetamine-salts-shp465-in-adults-with-adhd-results-of-a-phase-3-double-blind-randomized-forced-dose-trial
#2
Glen Frick, Brian Yan, Lenard A Adler
OBJECTIVE: Evaluate the efficacy and tolerability of triple-bead mixed amphetamine salts (MAS) in ADHD. METHOD: Adults with ADHD Rating Scale IV (ADHD-RS-IV) total scores ≥32 were randomized to 6 weeks of triple-bead MAS (25, 50, or 75 mg) or placebo. The primary endpoint was ADHD-RS-IV total score change from baseline at end of study (EOS). RESULTS: Least squares mean (95% confidence interval [CI]) treatment differences for ADHD-RS-IV total score changes from baseline to EOS significantly favored triple-bead MAS (all doses combined: -10...
April 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28412886/a-long-term-open-label-safety-study-of-triple-bead-mixed-amphetamine-salts-shp465-in-adults-with-adhd
#3
Lenard A Adler, Glen Frick, Brian Yan
OBJECTIVE: The aim of this study was to evaluate the long-term safety of triple-bead mixed amphetamine salts (MAS) in adults with ADHD. METHOD: Adults meeting Diagnostic and Statistical Manual of Mental Disorders (4th ed., text rev.; DSM-IV-TR) ADHD criteria and satisfying study criteria from one of two antecedent studies were enrolled in this 52-week (dose titration, 4 weeks; dose maintenance, 11 months) open-label extension. The protocol included 12.5- to 75-mg triple-bead MAS but was amended to a maximum of 50-mg triple-bead MAS...
April 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28384980/anti-bacterial-efficacy-of-terminalia-chebula-terminalia-bellirica-embilica-officinalis-and-triphala-on-salivary-streptococcus-mutans-count-a-linear-randomized-cross-over-trial
#4
Smariti Saxena, Nagesh Lakshminarayan, Shanmukha Gudli, Manish Kumar
INTRODUCTION: From the oral health perspective, it is well established that microorganisms have an important role in caries aetiology. From the dawn of civilization, herbal plants have served an array of roles. Triphala a tradtional herbal Ayurvedic formula consists of three native fruits of india including Terminalia Chebula (T. chebula), Terminalia Bellirica (T. bellirica) and Embilica Officinalis (E. officinalis). As per Ayurvedic Formulary of India (AFI) Triphala is prepared by combining a 1:1:1 mixture of ground dry fruits called myrobalans...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28383364/a-phase-3-multicenter-open-label-12-month-extension-safety-and-tolerability-trial-of-lisdexamfetamine-dimesylate-in-adults-with-binge-eating-disorder
#5
Maria Gasior, James Hudson, Javier Quintero, M Celeste Ferreira-Cornwell, Jana Radewonuk, Susan L McElroy
BACKGROUND: A 12-month, open-label extension study assessed the long-term safety and tolerability of lisdexamfetamine dimesylate (LDX) in adults with binge eating disorder (BED). METHODS: Adults (aged 18-55 y) with BED who completed 1 of 3 antecedent studies were enrolled in a 52-week, open-label extension study (dose optimization, 4 weeks [initial titration dose, 30-mg LDX; target doses, 50- or 70-mg LDX]; dose maintenance, 48 weeks). Safety evaluations included the occurrence of treatment-emergent adverse events (TEAEs), vital sign and weight assessments, and Columbia-Suicide Severity Rating Scale responses...
June 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28353022/topical-application-of-morphine-for-wound-healing-and-analgesia-in-patients-with-oral-lichen-planus-a-randomized-double-blind-placebo-controlled-study
#6
Ruth Zaslansky, Cynthia Schramm, Christoph Stein, Claas Güthoff, Andrea Maria Schmidt-Westhausen
OBJECTIVE: The objective of this study was to investigate the effect of topical morphine on erosive/ulcerative lesions in patients with oral lichen planus (OLP). Previous studies reported on an enhanced remission of skin wounds when morphine was applied topically. MATERIALS AND METHODS: This was single-center, prospective, double-blind, placebo-controlled, randomized, multi-arm (3), phase II study (RCT). Patients diagnosed with erosive and/or ulcerative OLP applied 0...
March 28, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28303381/differences-in-dietary-intake-during-chemotherapy-in-breast-cancer-patients-compared-to-women-without-cancer
#7
Y C de Vries, M M G A van den Berg, J H M de Vries, S Boesveldt, J Th C M de Kruif, N Buist, A Haringhuizen, M Los, D W Sommeijer, J H N Timmer-Bonte, H W M van Laarhoven, M Visser, E Kampman, R M Winkels
PURPOSE: Breast cancer patients receiving chemotherapy often experience symptoms such as nausea, vomiting and loss of appetite that potentially affect dietary habits. This study assessed the intake of energy, macronutrients and food groups before and during chemotherapy in breast cancer patients compared with women without cancer, and determined the association between symptoms and energy and macronutrient intake. METHODS: This study included 117 newly diagnosed breast cancer patients scheduled for chemotherapy and 88 women without cancer...
March 16, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28300854/randomized-placebo-and-active-controlled-crossover-study-of-the-safety-and-efficacy-of-thvd-102-a-fixed-dose-combination-of-oxybutynin-and-pilocarpine-in-subjects-with-primary-focal-hyperhidrosis
#8
David M Pariser, Janakan Krishnaraja, Thomas M Tremblay, R Michael Rubison, Ted W Love, Benjamin F McGraw
BACKGROUND: While muscarinic antagonists (anticholinergics) have shown efficacy in treating primary focal hyperhidrosis (PFH), side effects - most commonly dry mouth - are intolerable for most patients. THVD-102, a fixed-dose combination product has been developed combining oxybutynin, a muscarinic antagonist, and pilocarpine, a muscarinic agonist. The pilocarpine is at a dose level and release profile optimized to correct salivary flow impaired by oxybutynin yet not interfere with the therapeutic muscarinic antagonist effect of oxybutynin upon the sweat glands...
February 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28299770/does-systemic-disease-aggravate-the-severity-of-dry-mouth-by-anticholinergics-in-overactive-bladder-patients
#9
Keon-Cheol Lee, Bong-Mo Seong
PURPOSE: In overactive bladder (OAB) patients with systemic diseases, dry mouth tends to be more prominent owing to the effects of systemic diseases or related medications. We evaluated how systemic diseases affect dry mouth before and after anticholinergic treatment. MATERIALS AND METHODS: OAB patients were enrolled in this study. The patients were divided according to the presence or absence of systemic diseases. Patients with systemic diseases were sub-grouped by the number of systemic diseases (only one or more than one disease)...
March 16, 2017: Urology Journal
https://www.readbyqxmd.com/read/28299626/efficacy-and-safety-of-escitalopram-in-treatment-of-severe-depression-in-chinese-population
#10
Tianmei Si, Gang Wang, Fude Yang, Yiru Fang, Maosheng Fang, Jijun Li, Jicheng Dong, Xinhua Shen, Jianmin Zhuo, Qing Rui, Jinan Wang, Hu Cuili
Severe depression accounts for one-third of depressed patients. Increasing severity of depression usually hinders patients from achieving remission. This study evaluated the efficacy and safety of escitalopram in acute-phase treatment of severe major depressive disorder (MDD). A total of 225 participants with severe MDD (Diagnostic and Statistical Manual of Mental Disorders, 4th Edition criteria), with a current depressive episode and Montgomery-Asberg Depression Rating Scale (MADRS) score of ≥30 were enrolled...
March 15, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28298775/a-comparative-study-of-intravenous-dexmedetomidine-and-intravenous-clonidine-for-postspinal-shivering-in-patients-undergoing-lower-limb-orthopedic-surgeries
#11
Manohar Panneer, Prakash Murugaiyan, Sufala Viswas Rao
BACKGROUND: Dexmedetomidine and clonidine have been used for the prevention and treatment of shivering following spinal blockade. A prospective randomized, double-blinded study was conducted to compare the efficacy and safety of dexmedetomidine and clonidine in controlling postspinal shivering. METHODS: A total of sixty participants of equal sex, aged between 18 and 60 years of American Society of Anesthesiologists (ASA) I/II Class, who underwent orthopedic lower limb surgeries under spinal anesthesia with ≥Grade III shivering were randomly divided into two groups, Group D (n = 30) received injection dexmedetomidine 0...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28288692/does-cimicifuga-racemosa-have-the-effects-like-estrogen-on-the-sublingual-gland-in-ovariectomized-rats
#12
Yun-Meng Da, Kai-Yu Niu, Shu-Ya Liu, Ke Wang, Wen-Juan Wang, Jing Jia, Li-Hua Qin, Wen-Pei Bai
BACKGROUND: Cimicifuga racemosa is one of the herbs used for the treatment of climacteric syndrome, and it has been cited as an alternative therapy to estrogen. Apart from hectic fevers, dyspareunia and so on, dry mouth also increase significantly after menopause. It has not yet been reported whether C. racemosa has any impact on the sublingual gland, which may relate to dry mouth. In an attempt to determine this, we have compared the effects of estrogen and C. racemosa on the sublingual gland of ovariectomized rats...
March 14, 2017: Biological Research
https://www.readbyqxmd.com/read/28286566/gastrointestinal-manifestations-of-mitochondrial-disorders-a-systematic-review
#13
REVIEW
Josef Finsterer, Marlies Frank
Mitochondrial disorders (MIDs) due to respiratory-chain defects or nonrespiratory chain defects are usually multisystem conditions [mitochondrial multiorgan disorder syndrome (MIMODS)] affecting the central nervous system (CNS), peripheral nervous system, eyes, ears, endocrine organs, heart, kidneys, bone marrow, lungs, arteries, and also the intestinal tract. Frequent gastrointestinal (GI) manifestations of MIDs include poor appetite, gastroesophageal sphincter dysfunction, constipation, dysphagia, vomiting, gastroparesis, GI pseudo-obstruction, diarrhea, or pancreatitis and hepatopathy...
January 2017: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/28280616/differences-in-symptom-occurrence-severity-and-distress-ratings-between-patients-with-gastrointestinal-cancers-who-received-chemotherapy-alone-or-chemotherapy-with-targeted-therapy
#14
Ilufredo Y Tantoy, Anand Dhruva, Janine Cataldo, Alan Venook, Bruce A Cooper, Steven M Paul, Jon D Levine, Yvette P Conley, Frances Cartwright, Kathryn Lee, Fay Wright, Christine Miaskowski
BACKGROUND: Approximately 28% of patients with gastrointestinal (GI) cancers will receive targeted therapy (TT) because of the associated increases in survival. Only four studies have examined the symptom experience of these patients. To date, no studies have evaluated for differences in symptom occurrence, severity, and distress between patients who received chemotherapy (CTX) alone (n=304) or CTX with TT (n=93). METHODS: Patients completed self-report questionnaires, approximately one week after they received CTX...
February 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28270954/the-attitudes-of-urologists-and-gynecologists-about-overactive-bladder-and-treatment-of-it-in-turkey-a-questionnaire-survey
#15
Burhan Coşkun, Ömer Bayrak, Murat Dinçer, Kadir Önem, Cenk Gürbüz, Rahmi Onur
OBJECTIVE: We aimed to review the approaches of urologist and gynecologist in the management of overactive bladder (OAB). MATERIAL AND METHODS: A questionnaire consisting of 12 items were answered by 375 urologist and 46 gynecologist. The differences between frequency of encountering OAB, their viewpoints concerning conservative treatment, and their experience related to anticholinergic drug use and the management of refractory OAB were compared. RESULTS: The majority of the urologists, and gynecologists responded to the question "How often do you encounter OAB patients in your daily practice?" as 'in 10-25, and 50% of our patients', respectively (<0...
March 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28270706/patients-with-burning-mouth-sensations-a-clinical-investigation-of-causative-factors-in-a-group-of-compete-denture-wearers-jordanian-population
#16
Gadeer Elea Mukatash-Nimri, Marwan A Al-Nimri, Omar G Al-Jadeed, Zaid R Al-Zobe, Khuzama K Aburumman, Nader A Masarwa
AIM: To find out the prevalence of "true" burning mouth syndrome and study the association between patients' spontaneous complaints of burning mouth and systemic conditions in a group of middle age and elderly "denture wearers" patients in Jordan. METHODS: A group of 129 patients (112 female and 17 male) of "complete denture wearers" subjects aged 40 years and over attended prosthetic clinic at King Hussein Medical Hospital complaining from oral burning, with no oral lesion possibly responsible for the burning sensations were selected...
January 2017: Saudi Dental Journal
https://www.readbyqxmd.com/read/28228331/-efficacy-and-safety-of-available-therapies-in-the-management-of-idiopathic-overactive-bladder-a-systematic-review-of-the-literature
#17
J Moyson, F Legrand, M Vanden Bossche, T Quackels, T Roumeguère
OBJECTIVE: Study the efficacy and adverse events of different pharmacological lines in the treatment of idiopathic overactive bladder (iOAB). METHODS: PubMed research on meta-analyses and randomized controlled trials (RCT) focused on the efficacy and adverse effects of anticholinergics, botulinum toxin and mirabegron since 2005. RESULTS: Ten meta-analyses of anticholinergics were selected; 16 randomized controlled trials (ERC) comparing botulinum toxin A to either anticholinergic or placebo and 10 ERC studying mirabegron...
February 19, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28209359/safety-and-efficacy-of-fimasartan-in-mexican-patients-with-grade-1-2-essential-hypertension
#18
Ernesto G Cardona-Muñoz, Agustín López-Alvarado, Ignacio Conde-Carmona, Gerardo Sánchez-Mejorada, Sara Pascoe-González, Ramiro G Banda-Elizondo, Armando García-Castillo, Guillermo González-Gálvez, Raúl G Velasco-Sánchez, Maricela Vidrio-Velázquez, José L Leiva-Pons, Efraín Villeda-Espinosa, Arturo Guerra-López, Ramón M Esturau-Santalo
OBJECTIVE: To evaluate efficacy and safety of 60mg and 120mg Fimasartan (FMS) alone or combined with 12.5mg hydrochlorothiazide (HCTZ) in Mexican population. METHODS: Six month, treat-to-target, open study in subjects with grade 1-2 hypertension. Subjects were initially treated with 60mg FMS once daily; on week 8, those with Diastolic Blood Pressure (DBP) <90mmHg continued on the same FMS dose during the rest of the study while those with DBP ≥90mmHg were randomized to either 120mg FMS or 60mg FMS+12...
February 10, 2017: Archivos de Cardiología de México
https://www.readbyqxmd.com/read/28203322/congenital-ichthyosis-a-case-treated-successfully-with-acitretin
#19
Selvi Gulasi
INTRODUCTION: Lamellar ichthyosis (collodion baby) is a cornification disorder classified under the category of autosomal recessive congenital ichthyosis and characterized by hyperkeratosis. Early-stage retinoid treatment has been shown to improve survival in these patients. In this article, a lamellar ichthyosis case is presented of an infant who had the symptoms at birth and was treated successfully with acitretin. CASE PRESENTATION: A term newborn infant presented after delivery...
October 2016: Iranian Journal of Pediatrics
https://www.readbyqxmd.com/read/28196783/symptom-cluster-trajectories-during-chemotherapy-in-breast-cancer-outpatients
#20
Hsin-Tien Hsu, Kuan-Chia Lin, Li-Min Wu, Chiung-Hui Juan, Ming-Feng Hou, Shiow-Li Hwang, Yi Liu, Marylin J Dodd
CONTEXT: Breast cancer patients often experience multiple symptoms and substantial discomfort. Some symptoms may occur simultaneously and throughout the duration of chemotherapy treatment OBJECTIVES: The aim of this study was to investigate symptom severity and symptom cluster trajectories during chemotherapy in outpatients with breast cancer in Taiwan. METHODS: This prospective, longitudinal, repeated measures study administered a standardized questionnaire (M...
February 11, 2017: Journal of Pain and Symptom Management
keyword
keyword
97779
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"