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thyroid AND meta-analysis

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https://www.readbyqxmd.com/read/28812918/tyrosine-kinase-inhibitors-for-advanced-or-metastatic-thyroid-cancer-a-meta-analysis-of-randomized-controlled-trials
#1
Jen-Wei Liu, Chiehfeng Chen, El-Wui Loh, Chun-Cheng Chu, Mu-Yi Wang, Hsin-Ju Ouyang, Ya-Ting Chang, Wei-Zhan Zhuang, Ching-Wen Chou, Der-Jr Huang, Chia-Hwa Lee, Yun Yen, Ka-Wai Tam
BACKGROUND AND AIMS: Radioiodine-refractory advanced or metastatic thyroid cancer has poor prognosis. We conducted a meta-analysis of randomized controlled trials to evaluate the effectiveness and safety of tyrosine kinase inhibitors (TKIs) for advanced or metastatic thyroid cancer treatment. METHODS: Studies published until April 2017 were selected. The pooled effect size was calculated through meta-analysis by using random effects models. Outcomes were overall survival (OS), progression-free survival (PFS), objective response rate (RR), and adverse events (AEs)...
August 16, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28807633/evaluating-the-effectiveness-of-prophylactic-central-neck-dissection-with-total-thyroidectomy-for-cn0-papillary-thyroid-carcinoma-an-update-meta-analysis
#2
REVIEW
W-J Zhao, H Luo, Y-M Zhou, W-Y Dai, J-Q Zhu
BACKGROUND: The effectiveness of prophylactic central neck dissection (pCND) following total thyroidectomy (TT) in patients with clinical node-negative (cN0) papillary thyroid carcinoma (PTC) is still controversial. The aim of the meta-analysis is to evaluate the outcome of pCND and provide quantitative evidence. METHOD: A detailed literature search of PubMed, EMBASE, ClinicalTrails.gov and Cochrane Library electronic databases for articles published until October 2016 was carried out...
August 3, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28800068/galectin-3-performance-in-histologic-a-cytologic-assessment-of-thyroid-nodules-a-systematic-review-and-meta-analysis
#3
REVIEW
Pierpaolo Trimboli, Camilla Virili, Francesco Romanelli, Anna Crescenzi, Luca Giovanella
The literature on Galectin-3 (Gal-3) was systematically reviewed to achieve more robust information on its histologic reliability in identifying thyroid cancers and on the concordance between Gal-3 test in histologic and cytologic samples. A computer search of the PubMed and Scopus databases was conducted by combinations of the terms thyroid and Gal-3. Initially, 545 articles were found and, after their critical review, 52 original papers were finally included. They reported 8172 nodules with histologic evaluation of Gal-3, of which 358 with also preoperative FNAC Gal-3 assessment...
August 11, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28747386/the-association-of-autoimmune-thyroid-disease-aitd-with-psoriatic-disease-a-prospective-cohort-study-systematic-review-and-meta-analysis
#4
Samer R Khan, Arjola Bano, Marlies Wakkee, Tim Korevaar, Oscar Franco, Tamar Nijsten, Robin P Peeters, L Chaker
Objective Autoimmune thyroid disease (AITD) and psoriatic disease share auto-immunological components. Few studies have investigated the link between both, yielding inconclusive results. Design We assessed the association of AITD with psoriatic disease in a prospective cohort study, and performed a systematic review and meta-analysis. Methods 8,214 participants of the Rotterdam Study (RS) with thyroid peroxidase antibodies (TPO-Abs), thyroid stimulating hormone (TSH) and/or free thyroxine (FT4) measurements and information on psoriatic disease were included...
July 26, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28740401/the-diagnostic-and-prognostic-values-of-ki-67-mib-1-expression-in-thyroid-cancer-a-meta-analysis-with-6-051-cases
#5
REVIEW
Deng-Hua Pan, Dong-Yue Wen, Yi-Huan Luo, Gang Chen, Hong Yang, Jun-Qiang Chen, Yun He
BACKGROUND: Growing evidence has demonstrated that Ki-67/MIB-1 has an effect on the clinical progression and prognosis in cancers. However, the diagnostic and prognostic values of Ki-67/MIB-1 in thyroid cancer remain unclear. MATERIALS AND METHODS: The meta-analysis was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Studies were retrieved from PubMed, EBSCO, EMBASE, ISI Web of Science, China National Knowledge Infrastructure, WanFang and Chinese VIP databases...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28723620/association-between-8q24-rs6983267-polymorphism-and-cancer-susceptibility-a-meta-analysis-involving-170-737-subjects
#6
Man Zhu, Xue Wen, Xuefang Liu, Yingchao Wang, Chunzi Liang, Jiancheng Tu
Published data on the association between 8q24 rs6983267 polymorphism and cancer risk are inconsistent. Thus, we conducted a meta-analysis to evaluate the relationship between rs6983267 polymorphism and cancer risk. We searched on PubMed, EMBASE, Web of Science and China National Knowledge Infrastructure (CNKI) up to November 1, 2016 for relevant studies. Odds ratios (ORs) and 95% confidence intervals (CIs) were used to estimate the strength of this association. We included 78 case-control studies with a total of 73,996 cases and 96,741 controls in this meta-analysis...
July 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28679865/a-meta-analysis-of-hashimoto-s-thyroiditis-and-papillary-thyroid-carcinoma-risk
#7
Xingjian Lai, Yu Xia, Bo Zhang, Jianchu Li, Yuxin Jiang
OBJECTIVE: It remains inconclusive whether Hashimoto's thyroiditis (HT) predisposes patients to the development of papillary thyroid carcinoma (PTC). We conducted a meta-analysis of the available data to address this question. RESULTS: Twenty-seven eligible studies were selected, including 18 archival thyroidectomy studies, 6 fine-needle aspiration (FNA) studies, and 3 selective FNA or thyroidectomy studies. A total of 76,281 patients, including 12,476 cases of thyroid cancer, were included in these studies...
June 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28678751/association-between-cd40-rs1883832-and-immune-related-diseases-susceptibility-a-meta-analysis
#8
Jiaxuan Qin, Jinchun Xing, Rongfu Liu, Bin Chen, Yuedong Chen, Xuan Zhuang
BACKGROUND/OBJECTIVE: It has been reported that CD40 rs1883832 might be associated with immune-related diseases susceptibility. Owing to mixed and inconclusive results, we conducted a meta-analysis of case-control studies to summarize and clarify this association.Methods/main results: A systematic search of studies on the association between CD40 rs1883832 and immune-related diseases susceptibility was conducted in databases. Odds ratios and 95% confidence intervals were used to pool the effect size...
June 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28666074/prognostic-implication-of-braf-and-tert-promoter-mutation-combination-in-papillary-thyroid-carcinoma-a-meta-analysis
#9
REVIEW
Huy Gia Vuong, Ahmed M A Altibi, Uyen N P Duong, Lewis Hassell
INTRODUCTION: he use of molecular markers, especially BRAF and TERT promoter mutations, for risk stratification in papillary thyroid carcinoma (PTC) is subject to continuing debate. In this study, we aimed to investigate the clinicopathological implication of each genotype when combining BRAF and TERT promoter mutations in PTCs. METHODS: We searched four electronic databases including PubMed, Scopus, Web of Science and Virtual Health Library for relevant studies...
June 30, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28653886/the-mir-608-rs4919510-polymorphism-may-modify-cancer-susceptibility-based-on-type
#10
Shuangshuang Wu, Weiyan Yuan, Yu Shen, Xiao Lu, Yue Li, Tian Tian, Liying Jiang, Xun Zhuang, Jianqing Wu, Minjie Chu
Previous meta-analysis has not shown different effects of miR-608 rs4919510 polymorphism in specific cancer types and reported no significant association between rs4919510 and cancer risk among Chinese. However, more recent findings have been inconsistent. Therefore, we performed an updated meta-analysis to examine whether this polymorphism is associated with cancer risk based on ethnicity and type. A total of 18 case-control studies, comprising 12,517 cases and 15,624 controls, were included in our study. Surprisingly, in contrast with previous meta-analysis, a significant association between the rs4919510 polymorphism and cancer risk was observed in Chinese (CG vs CC: odds ratio = 1...
June 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28640139/a-prisma-compliant-systematic-review-and-meta-analysis-of-the-relationship-between-thyroid-disease-and-different-levels-of-iodine-intake-in-mainland-china
#11
REVIEW
Wanwen Weng, Mengjie Dong, Jun Zhan, Jun Yang, Bo Zhang, Xingdong Zhao
BACKGROUND: Low-iodine intake has historically been an issue in China, causing widespread iodine deficiency diseases (IDD). China started to introduce universal salt iodization in 1995, but reports of increased thyroid disease are a concern and appropriate levels of iodine intake must be considered. OBJECTIVE: To assess the prevalence of thyroid disease with different urinary iodine concentrations (UICs) in the general population of those residing in mainland China...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28588772/ultrasound-guided-core-needle-biopsy-for-differential-diagnosis-of-thyroid-nodules-a-systematic-review-and-meta-analysis
#12
Na Liu, Zhaowei Meng, Qiang Jia, Xianghui He, Weijun Tian, Jian Tan, Yujie Zhang, Xue Li, Tianpeng Hu, Pingping Zhou, Sen Wang, Arun Upadhyaya
Ultrasound-guided core needle biopsy (US-CNB) of thyroid nodules is a relatively new technique used in surgical workup. However, no systematic review of this method has yet been performed. In the present meta-analysis, literature databases consisting of Cochrane Library, Medline, Embase, Scopus and Google Scholar were searched. Following eligibility assessments of the studies, quality appraisals were performed on the included studies using the Quality Assessment Tool for Diagnostic Accuracy Studies-2 method...
June 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28585717/a-meta-analysis-of-intraoperative-neuromonitoring-of-recurrent-laryngeal-nerve-palsy-during-thyroid-reoperations
#13
Wei Sun, Jinhao Liu, Hao Zhang, Ping Zhang, Zhihong Wang, Wenwu Dong, Liang He, Ting Zhang
BACKGROUND: The rate of recurrent laryngeal nerve (RLN) palsy, a common complication of thyroid surgery, is especially high in thyroid reoperations. The present meta-analysis assesses whether intraoperative neuromonitoring (IONM) reduces the prevalence of RLN palsy in thyroid reoperations. DESIGN AND METHODS: A systematic literature search was conducted in the PubMed, SCIE, and Wan Fang databases for studies published up to August 31, 2016. All data were analysed using STATA (version 11) software...
June 6, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28575853/percutaneous-laser-ablation-for-benign-thyroid-nodules-a-meta-analysis
#14
REVIEW
Wei Fan Sui, Jian Yun Li, Jian Hua Fu
PURPOSE: To evaluate percutaneous laser ablation in treating benign thyroid nodules, we conducted a meta-analysis based on summarizing existing researches. MATERIALS AND METHODS: A literature search for clinical trial was performed in PubMed, Cochrane Library and Excerpt Medica Database. The qualities of included studies were evaluated. We calculated the indexes with mean difference. Heterogeneity and publication bias were tested and explored. We performed subgroup analyses and sensitivity analysis further...
May 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/28574441/gene-expression-mrna-markers-for-differentiating-between-malignant-and-benign-follicular-thyroid-tumours
#15
Bartosz Wojtas, Aleksandra Pfeifer, Malgorzata Oczko-Wojciechowska, Jolanta Krajewska, Agnieszka Czarniecka, Aleksandra Kukulska, Markus Eszlinger, Thomas Musholt, Tomasz Stokowy, Michal Swierniak, Ewa Stobiecka, Ewa Chmielik, Dagmara Rusinek, Tomasz Tyszkiewicz, Monika Halczok, Steffen Hauptmann, Dariusz Lange, Michal Jarzab, Ralf Paschke, Barbara Jarzab
Distinguishing between follicular thyroid cancer (FTC) and follicular thyroid adenoma (FTA) constitutes a long-standing diagnostic problem resulting in equivocal histopathological diagnoses. There is therefore a need for additional molecular markers. To identify molecular differences between FTC and FTA, we analyzed the gene expression microarray data of 52 follicular neoplasms. We also performed a meta-analysis involving 14 studies employing high throughput methods (365 follicular neoplasms analyzed). Based on these two analyses, we selected 18 genes differentially expressed between FTA and FTC...
June 2, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28566564/effect-of-thyroxin-treatment-on-carotid-intima-media-thickness-cimt-reduction-in-patients-with-subclinical-hypothyroidism-sch-a-meta-analysis-of-clinical-trials
#16
Muhammad Aziz, Yugandhar Kandimalla, Archana Machavarapu, Anshul Saxena, Sankalp Das, Adnan Younus, Michelle Nguyen, Rehan Malik, Dixitha Anugula, Muhammad A Latif, Choudhry Humayun, Idrees M Khan, Ali Adus, Aisha Rasool, Emir Veledar, Khurram Nasir
AIM: Research shows that subclinical hypothyroidism (SCH) is related to an increased carotid intima-media thickness (CIMT), a surrogate marker of subclinical cardiovascular disease (CVD). It is controversial whether or not SCH should be treated to reduce CVD morbidity and mortality. This meta-analysis aimed to determine whether SCH is associated with an increase in CIMT as compared to Euthyroidism (EU) and whether thyroxin (T4) treatment in SCH can reverse the change in CIMT. METHODS: Two independent reviewers conducted an extensive database research up to December 2016...
July 1, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28566444/prognostic-impact-of-vascular-invasion-in-differentiated-thyroid-carcinoma-a-systematic-review-and-meta-analysis
#17
Huy Gia Vuong, Tetsuo Kondo, Uyen N P Duong, Thong Quang Pham, Naoki Oishi, Kunio Mochizuki, Tadao Nakazawa, Lewis Hassell, Ryohei Katoh
BACKGROUND: The role of vascular invasion (VI) as a prognostic marker in thyroid cancer is continuously debated among investigators. In this systematic review and meta-analysis, we aimed to investigate the association of VI with tumor recurrence and patient mortality in differentiated thyroid cancers (DTCs). METHODS: We searched five electronic databases for cases of DTC matching our criteria. Data of tumor persistence, locoregional recurrence (LRR), distant recurrence (DR) and overall recurrence/persistence (RP) were extracted and pooled into odds ratios (OR) and corresponding 95% confidence intervals (CIs) using random effect model...
August 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28565997/safety-of-radiofrequency-ablation-of-benign-thyroid-nodules-and-recurrent-thyroid-cancers-a-systematic-review-and-meta-analysis
#18
Sae Rom Chung, Chong Hyun Suh, Jung Hwan Baek, Hye Sun Park, Young Jun Choi, Jeong Hyun Lee
OBJECTIVE: We performed a systematic review and meta-analysis to evaluate the safety of radiofrequency ablation (RFA) for the treatment of benign thyroid nodules and recurrent thyroid cancers. MATERIALS AND METHODS: Ovid-MEDLINE, EMBASE, and Library of Cochrane databases were searched up to July 12, 2016 for studies on the safety of RFA for treating benign thyroid nodules or recurrent thyroid cancers. Pooled proportions of overall and major complications were assessed using random-effects modeling...
June 1, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28561328/inferior-thyroid-artery-ligation-increases-hypocalcemia-after-thyroidectomy-a-meta-analysis
#19
Alvaro Sanabria, Luiz P Kowalski, Francesco Tartaglia
OBJECTIVE: To assess the effect of truncal ligation of the inferior thyroid artery in comparison with ligation of secondary branches as a risk factor for postoperative hypocalcemia. DATA SOURCES: A search was conducted using the Medical Subject Headings and free-text terms "thyroid*" and "truncal ligation*" in PubMed Central, PubMed, Embase, and Latin American and Caribbean Health Sciences Literature databases for trials published between January 1985 and October 2016...
May 31, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28546524/light-alcohol-drinking-and-risk-of-cancer-a-meta-analysis-of-cohort-studies
#20
Yoon-Jung Choi, Seung-Kwon Myung, Ji-Ho Lee
Purpose: To determine whether light alcohol drinking increases the risk of cancer by using a meta-analysis of cohort studies because the newly revised 2015 European Code against Cancer 4th edition on alcohol and cancer was based on critical flaws in the interpretation and citation of the previous meta-analyses. Materials and Methods: PubMed and EMBASE were searched in April, 2016. Two authors independently reviewed and selected cohort studies on the association between very light (≤0...
May 22, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
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